This review summarizes the latest trends and developments of isoxazole-enabled alkyne amination reactions and their applications in divergent heterocycle synthesis.
This review summaries the advances in Au-catalyzed asymmetric alkyne transformations over the past two decades. It is organized by the key intermediates and the chirality induction models, offering a toolkit for the implement of asymmetric catalysis.
A catalytic convergent assembly of a 6–6 bis-heterocyclic ring in one-go from the gold-catalyzed cycloisomerization of o-azidoarylynones in the presence of an anthranil with sequential C–N and C–O bond formation has been developed.
Synthetic potential of ynamides and ynamide-derived advanced intermediates in cycloaddition reactions with different reaction partners to yield versatile heterocyclic adducts.
Heterogeneous gold(III)-catalyzed annulation of anthranils and ynamides towards formylindoles using an MCM-41-anchored dichloro(pyridine-2-carboxylato)gold(III) complex [MCM-41-PicAuCl2] as a recyclable catalyst is described.