A new class of fused imidazonaphthyridine N,N,N-ligands were used for nickel-catalyzed ethylene dimerization, achieving high activity with high selectivity. Isolation of a key Ni–Al intermediate elucidates the critical role of the co-catalyst.
A series of novel 2,7-naphthyridine derivatives were designed with potential applications in optical switching. The electronic properties and nonlinear optical properties of the designed compounds were extensively studied using DFT.
This review highlights advances in one-pot multicomponent synthesis of naphthyridine derivatives, focusing on efficient, atom-economical methods, diverse scaffolds and mechanistic insights fostering innovation in organic synthesis.
An 131I-labeled α-amylase inhibitor shows exceptional stomach retention (59.6% ID per g) and sustained intestinal uptake, highlighting its promise as a GI-targeted antidiabetic agent and potential GI imaging probe.
A silver-catalyzed one-pot, regio- and chemoselective synthesis of benzo[b][1,7]- and benzo[c][2,7]-naphthyridines via Michael addition–cyclization is reported, supported by NMR evidence and enabling access to novel perlolidine analogs.