The parahydrogen-induced polarisation (PHIP) NMR signal enhancement technique is used to study H2 addition to Vaska’s complex (trans-[IrCl(CO)(PPh3)2]) and a mixture of Vaska’s complex derivatives with benchtop (1 T) NMR detection.
A benchtop NMR instrument in combination with spectral hard modeling enabled monitoring and subsequent kinetic fitting of a chlorination reaction. Different modes were investigated, an NMR tube, re-circulating batch and single pass continuous flow.
On-line reaction monitoring of hydrogenation reactions of oxygen-sensitive organometallic complexes is done via a 31P benchtop NMR spectrometer using the Multi-Resonance Sensitive Homogeneous And Resolved PEaks in Real time (MR-SHARPER) sequence.
A comparison of ultra-resolved pure shift NMR techniques, mitigating the resolution problem of compact NMR instruments, showed that the J-resolved double echo is the most performant technique, enabling the profiling of biological complex mixtures.
Benchtop NMR analyses of bio-oils are made safer and more sustainable by replacing DMF with bio-derived solvents.