A green process for the synthesis of optically active tert-alcohols has been developed by combining lipase- and H2SO4-catalysed reactions in a biphasic recycling flow system.
This review explores the fascinating world of molecules featuring multiple stereogenic elements, unraveling the different strategies designed over the years for their enantioselective synthesis.
Asymmetric organocatalysis has acquired a prominent place in modern synthesis of noncanonical α-amino acids (ncAAs), valuable structural elements in organic synthesis, chemical biology, and medicine.
This review highlights recent advances in the atroposelective preparation of axially chiral azole derivatives, emphasizing mechanistic insights and synthetic applications in the development of this class of five-membered heterocyclic frameworks.
3-Aryl-3-hydroxy-2-oxindoles were racemised under acid-catalysis in a water-in-oil Pickering emulsion comprising toluene and aqueous H2SO4.