36 dibenzodiazepinone analogues were designed and synthesized, and their antiproliferative activities were evaluated. Compound 33 exhibited best inhibitory activity against Osimertinib resistant NSCLC cells.
Synthesis and fabrication of redox-switchable polymeric lipid hybrid nanocarriers that selectively deliver berberine and induce apoptosis in GSH-rich cancer cells while sparing healthy cells.
The activatable fluorescence probe Q-Atezol demonstrates great potential as an exceptional sensor for assessing PD-L1 expression in three-dimensional cell structures and for in vivo applications.
Novel bakuchiol derivatives containing thiosemicarbazone moieties exhibit cytotoxic activity against non-small cell lung cancer lines and inhibition of migration and invasion by suppressing EMT.
Lnc-TMEM132D-AS1 induces acquired resistance to osimertinib in NSCLC by the miR-766-5p/ENTPD1 axis.