We have developed an organocatalytic approach for the construction of a 2,3-dihydrobenzofuran scaffold through a formal [4 + 1] annulation of 2-(2-nitrovinyl)phenols and α-bromoacetophenones in the presence of DBU.
The first denitrative Pd(II)-catalyzed alkyne annulation reaction is reported for the synthesis of cyclopenta[b]chromanes.
A bifunctional tertiary amine catalyzed [3 + 2] annulation of nitrovinylindoles with azlactones has been developed, delivering a wide range of pyrrolo[1,2-a]indoles and pyrrolo[3,2,1-ij]quinoline in excellent results (53–92% yield, 53–96% ee).
The present review summarizes the recent advances (2018–2023) in stereoselective annulation involving p-benzoquinones for the construction of fused, spiro and bridged/cage frameworks.
Coronene diimide was explored for generation of a stable radical anion (>50 minutes) using H2S in 40% water, which was used as a biochemical sensor for the rapid detection of H2O2 (58.27 pM) and glucose (16 pM).