Novel curcumin-based analogues as potential VEGFR2 inhibitors with promising metallic loading nanoparticles: synthesis, biological evaluation, and molecular modelling investigation

Asmaa S. A. Yassen, Sherief M. Abdel-Wahab, Khaled M. Darwish, Mohamed S. Nafie, Reda F. A. Abdelhameed, Gharieb S. El-Sayyad, Ahmed I. El-Batal, Khadiga M. Attia, Hosam A. Elshihawy and Ranza Elrayess

RSC Med. Chem., 2024, 15, 4039
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Design, synthesis, biological evaluation and molecular docking study of novel quinolone derivatives as potent HDAC1 (Histone Deacetylase) inhibitors and anticancer agents

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Journal of Molecular Structure, 2025, 1325, 141011
DOI: 10.1016/j.molstruc.2024.141011

Unraveling Extremely Damaging IRAK4 Variants and Their Potential Implications for IRAK4 Inhibitor Efficacy

Mohammed Y. Behairy, Refaat A. Eid, Hassan M. Otifi, Heitham M. Mohammed, Mohammed A. Alshehri, Ashwag Asiri, Majed Aldehri, Mohamed Samir A. Zaki, Khaled M. Darwish, Sameh S. Elhady, Nahla H. El-Shaer and Muhammad Alaa Eldeen

JPM, 2023, 13, 1648
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Expanding potential of quinoline hydrazide/hydrazone derivatives as anticancer agents

Sangeeta Verma, Sukhbir Lal and Rakesh Narang

Future Medicinal Chemistry, 2024, 16, 1283
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Quinaldehyde o-Nitrobenzoylhydrazone: Structure and Sensitization of HepG2 Cells to Anti-Cancer Drugs

Valeri V. Mossine, Steven P. Kelley and Thomas P. Mawhinney

Compounds, 2025, 5, 24
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Integration of Chemoinformatics and Multi-Omics Analysis Defines ECT2 as a Potential Target for Cancer Drug Therapy

Mohamed A. Soltan, Muhammad Alaa Eldeen, Bayan H. Sajer, Reda F. A. Abdelhameed, Fawziah A. Al-Salmi, Eman Fayad, Ibrahim Jafri, Hebatallah Emam Mohammed Ahmed, Refaat A. Eid, Hesham M. Hassan, Mubarak Al-Shraim, Amr Negm, Ahmed E. Noreldin and Khaled M. Darwish

Biology, 2023, 12, 613
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In Silico and DFT Analysis of a vic-Dioxime Ligand Bearing a Hydrazone Moiety and Its Zinc(II) Complex

Nursabah Sarıkavaklı, Onur Genç and Şerife Gökçe Çalışkan

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2025, 15, 913
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Synthesis, Characterization and Biological Evaluation of New Enamide Fluorinated‐Schiff Base Derivatives as Potential Cytotoxic and Apoptosis‐Inducing Agents

Hany M. Abd El‐Lateef, Eslam E. M. Toson, Ali H. Abu Almaaty, Rasha Mohammed Saleem, Ali Hassan Ahmed Maghrabi, Elsherbiny H. El‐Sayed, Islam Zaki and Magdy M. Youssef

ChemistrySelect, 2023, 8
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Deciphering Molecular Aspects of Potential α-Glucosidase Inhibitors within Aspergillus terreus: A Computational Odyssey of Molecular Docking-Coupled Dynamics Simulations and Pharmacokinetic Profiling

Sameh S. Elhady, Noha M. Alshobaki, Mahmoud A. Elfaky, Abdulrahman E. Koshak, Majed Alharbi, Reda F. A. Abdelhameed and Khaled M. Darwish

Metabolites, 2023, 13, 942
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Exploration of antiproliferative potential of modified triazole–benzohydrazone scaffold: Multitarget approach

Alaa M. Ali, Mohamed A. Khalaf, Bhoomendra A. Bhongade, Khalid B. Selim and Amany S. Mostafa

Archiv der Pharmazie, 2024, 357
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