An in vivo study of the antihypertensive effects of the umami peptide AHSVRFY from Parma ham and its intestinal digestion

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Blue mussel (Mytilus edulis) water extract ameliorates intestinal immune response in high-fat diet–streptozotocin-induced diabetic mice

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Mussels as sustainable marine resources for bioactive peptides for health and the food industry

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Comparison of polysaccharides from stem barks and flowers of Magnolia officinalis: Compositional characterization, hypoglycemic and photoprotection activities

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International Journal of Biological Macromolecules, 2024, 283, 137766
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Identification of novel angiotensin I-converting enzyme inhibitory peptides from walnut (Juglans sigillata Dode) protein hydrolysates and their vascular endothelial protective properties: In silico and in vitro studies

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Comparison of Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis Lipid Extracts Effects on UVA-Induced Changes in Human Skin Fibroblasts Proteome

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Marine Drugs, 2024, 22, 509
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Simultaneous effect of different chromatographic conditions on the chromatographic retention of pentapeptide derivatives (HGRFG and NPNPT)

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In Vitro Intestinal Transepithelial Transport, Safety, and Bioactivity Evaluation of Milk Peptides

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Journal of Food Biochemistry, 2025, 2025
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RETRACTED: Screening and Exploring the Application of the Multifunctional Antioxidant Peptides MSWLC and TSWLC

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Antioxidant and Anti-fatigue Activities of Seeds Oil of Ribes stenocarpum Maxim. from the Qinghai-Tibet Plateau

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Unconventional production strategies, action mechanisms, and structure-functional attributes of food-derived peptides

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Valorization of fish processing by-products for protein hydrolysate recovery: Opportunities, challenges and regulatory issues

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Production, characterisation, and biological properties of Tenebrio molitor-derived oligopeptides

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Structural characterization and in vitro anti-inflammatory activity of exopolysaccharide produced by Pediococcus pentosaceus 4412

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Preparation and Vasodilation Mechanism of Angiotensin-I-Converting Enzyme Inhibitory Peptide from Ulva prolifera Protein

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Production of Protein Hydrolysates Teff (Eragrostis tef) Flour with Antioxidant and Angiotensin-I-Converting Enzyme (ACE-I) Inhibitory Activity Using Pepsin and Cynara cardunculus L. Extract

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Purification, characterization, and toxicity of antioxidative peptides from ultrasonicated chickpea (Cicer arietinum L.) protein hydrolysate

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Cyperus peptide SFRWQ inhibits oxidation and inflammation in RAW264.7 cell model

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Identification of novel cancer chemopreventive peptides from bran residue of Riceberry cultivated in Northern Thailand

Aroonrat Pharapirom, Phatthawin Setthaya, Arpamas Vachiraarunwong, Akkasit Jongjareonrak, Kenji Sato, Rawiwan Wongpoomchai and Jetsada Ruangsuriya

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Tuna sidestream valorization: a circular blue bioeconomy approach

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The potential of protein hydrolysates from marine by-products: Mechanisms, health benefits, applications, future prospects, and challenges

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Two novel angiotensin‐converting enzyme (ACE) and dipeptidyl peptidase IV (DPP‐IV) inhibiting peptides from tilapia (Oreochromis mossambicus) skin and their molecular docking mechanism

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Functional food candidate from Indonesian green algae Caulerpa racemosa (Försskal) J. Agardh by two extraction methods: Metabolite profile, antioxidant activity, and cytotoxic properties

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Preparation, structural characterization, and performance evaluation of antler plate collagen peptide-calcium chelates

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Optimization of the Preparation Process and Ameliorative Efficacy in Osteoporotic Rats of Peptide–Calcium Chelates from Skipjack Tuna (Katsuwonus pelamis) Meat

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Differences in extraction methods influence the physicochemical properties, antiradical, and anti-inflammatory effects of porphyran from Pyropia dentata

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A novel angiotensin I-converting enzyme (ACE) inhibitory peptide from Wuyi rock tea residue: Preparation, identification, and its potential molecular mechanism

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Separation, purification, structure characterization, and immune activity of a polysaccharide from Alocasia cucullata obtained by freeze-thaw treatment

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A galactoglucomannan from Termitomyces intermedius: Structural characterization, anti-obesity and anti-inflammatory activities

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WITHDRAWN: Fractional ethanol precipitation of Gastrodiae Rhizoma -derived glucans triggers caspase-mediated apoptosis across diverse cancer cell lines.

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Research progress in the preparation and structure-activity relationship of bioactive peptides derived from aquatic foods

Zhenjie Mao, Hong Jiang, Jianan Sun, Yuanhui Zhao, Xin Gao and Xiangzhao Mao

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Purification, identification, and mechanism of action of novel antioxidant peptides from quinoa (Chenopodium quinoa wild.) protein hydrolysate

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Structures, antioxidant, and angiotensin I‐converting enzyme (ACE)‐inhibitory activities of peptides derived from protein hydrolysates of three phenolics‐rich legume genera

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Journal of Food Science, 2025, 90
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Investigating the impact of ultrasound-assisted extraction on the angiotensin-converting enzyme (ACE) inhibitory activity of chickpea (Cicer arietinum L.) peptides: In vitro, in silico, and acute toxicity study

Deia Tawalbeh, Muhammad Hussin Alu'datt, Wan Amir Nizam Wan Ahmad, Mannur Ismail Shaik, Nanda Kumar Yellapu, Hendrix Yulis Setyawan, Nurul Huda and Norizah Mhd Sarbon

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Soft-shelled turtle-derived antioxidant peptides inhibit advanced glycation end products (AGEs) formation and mitigate AGE-induced damage to HUVECs via the AGEs/RAGE signaling pathway

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Eighteen Novel Bioactive Peptides from Monkfish (Lophius litulon) Swim Bladders: Production, Identification, Antioxidant Activity, and Stability

Yan Sheng, Wan-Yi Wang, Ming-Feng Wu, Yu-Mei Wang, Wang-Yu Zhu, Chang-Feng Chi and Bin Wang

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Bioactive peptides of marine organisms: Roles in the reduction and control of cardiovascular diseases

Jia Du, Miao Xiao, Naomi Sudo and Qinghua Liu

Food Science & Nutrition, 2024, 12, 5271
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Therapeutic effects of blue mussel-derived peptides (PIISVYWK and FSVVPSPK) on non-alcoholic fatty liver disease by modulating lipid metabolism and inflammation in high-fat diet-induced mice

Indyaswan Tegar Suryaningtyas and Jae-Young Je

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GC‐MS/HPLC Profiling and Sono‐Maceration Mediated Extraction of Osbeckia Parvifolia Polyphenols: In Silico and In Vitro Analysis on Anti‐Proliferative Activity in Ovarian Cancer Cell Lines

Benedict Mathews Paul, Gowtham Kannan, Francis Jegan Raj, Vetri Velavan Sundararajan, Yamuna Annadurai, Shanmughavel Piramanayagam and Parimelazhagan Thangaraj

Chemistry & Biodiversity, 2025, 22
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Recent Advances on Bioactive Peptide Fractionation Methods

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Screening and mechanism of six angiotensin I-converting eneyme inhibitory peptides from protein hydrolysate of Coregonus peled visceral: A combined in computer and in vitro study

Yabo Wei, Xin Guo, Xuemei Fan, Yunfeng Zhao, Zhouping Wang, Xiaorong Deng and Jian Zhang

LWT, 2023, 188, 115426
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Exploring novel antioxidant cyclic peptides in corn protein hydrolysate: Preparation, identification and molecular docking analysis

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Food Chemistry, 2025, 464, 141747
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Unlocking the Potential of the Umami Taste-Presenting Compounds: A Review of the Health Benefits, Metabolic Mechanisms and Intelligent Detection Strategies

Rongrong Xia, Yitong Qiao, Heran Xu, Zhenshan Hou, Guanlin Qian, Yafei Wang, Yunting Li, Miao Yan, Song Pan and Guang Xin

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Antioxidant Peptides from Hizikia fusiformis: A Study of the Preparation, Identification, Molecular Docking, and Cytoprotective Function of H2O2-Damaged A549 Cells by Regulating the Keap1/Nrf2 Pathway

Shang Lv, Bin Hu, Su-Zhen Ran, Min Zhang, Chang-Feng Chi and Bin Wang

Foods, 2025, 14, 400
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Antioxidant Peptides from Monkfish Swim Bladders: Ameliorating NAFLD In Vitro by Suppressing Lipid Accumulation and Oxidative Stress via Regulating AMPK/Nrf2 Pathway

Ming-Feng Wu, Qing-Hao Xi, Yan Sheng, Yu-Mei Wang, Wan-Yi Wang, Chang-Feng Chi and Bin Wang

Marine Drugs, 2023, 21, 360
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Recent Advances in Marine-Derived Bioactives Towards Cancer Therapy

Nafisa Nawar Tamzi, Md Motiur Rahman and Subhadeep Das

IJTM, 2024, 4, 740
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Bioactive Peptides from Skipjack Tuna Cardiac Arterial Bulbs: Preparation, Identification, Antioxidant Activity, and Stability against Thermal, pH, and Simulated Gastrointestinal Digestion Treatments

Wei-Wei Cai, Xiao-Meng Hu, Yu-Mei Wang, Chang-Feng Chi and Bin Wang

Marine Drugs, 2022, 20, 626
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Novel ACE-Inhibitory Peptides from Royal Jelly Proteins: Comprehensive Screening, Mechanistic Insights, and Endothelial Protection

Wanyu Yang, Xinyu Zou, Tianrong Zhang, Qingqing Liu, Ziyan Liu, Fan Li, Yuhong Luo, Yiwen Wang, Zhijun Qiu and Bin Zhang

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Recent progress in the preparation, purification, characterization, encapsulation, and biological activities of peptides from shellfish

Shuangshuang Hu and Wanwen Chen

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A Novel Pentapeptide From Tilapia Skin Gelatin Gastrointestinal Digests Which Inhibits Scar Formation Through Anti‐Inflammatory and Antiangiogenesis

Yi Liu, Haiyan Zheng, Liyuan Lin, Huixue Huang, Chunxia Zhou, Pengzhi Hong, Zhong-Ji Qian and Yogesh Kumar

Journal of Food Biochemistry, 2024, 2024
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Preparation methods, inhibitory activity, and regulatory mechanisms of angiotensin-converting enzyme inhibitory peptides derived from eggs

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Food Bioscience, 2026, 79, 108759
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Novel Dipeptidyl Peptidase-IV (DPP-IV) Inhibitory Oligopeptides from Bovine Casein: Active Oligopeptides Screening, Enzyme and Cellular Validation, and Oligopeptide-Enzyme Binding Mechanisms

Ruibo Cao, Chi Zheng, Liangxiao Feng, Yan Liu, Sufang Duan, Jian He, Xuebo Liu and Lijun Sun

J. Agric. Food Chem., 2026, 74, 9344
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Mechanism of tilapia skin antioxidant pentapeptide on atherosclerosis: Inhibition of angiogenesis and oxidative stress

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Journal of Functional Foods, 2025, 133, 107009
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The polyphenol - altilisol from Artocarpus altilis leaves exhibits angiotensin-I converting enzyme inhibitory activity

Jalahalli M. Siddesha, Mahendra Mahadevaswamy, Pramod Halappa, Sushma Pradeep, Chandan Shivamallu, Vivek Hamse Kameshwar, Nanjundaswamy Vijendra Kumar and Bannikuppe Sannanaik Vishwanath

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Novel angiotensin-I-converting enzyme (ACE) inhibitory peptides from Porphyra haitanensis: Screening, digestion stability, and mechanistic insights

Xianjiang Ye, Ran Yang, Zhizhi Yang, Baote Huang, Talha Riaz, Chao Zhao and Jicheng Chen

Food Bioscience, 2025, 68, 106460
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From In Silico to a Cellular Model: Molecular Docking Approach to Evaluate Antioxidant Bioactive Peptides

Federica Tonolo, Alessandro Grinzato, Alberto Bindoli and Maria Pia Rigobello

Antioxidants, 2023, 12, 665
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Characterization of zinc-chelating peptides prepared from Arthrospira platensis proteins

Avisha Samimiazad, Saeed Mirdamadi, Abbas Akhavan Sepahi, Marjaneh Sedaghati and Maliheh Safavi

Food Bioscience, 2025, 65, 106096
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Bioactivity of Marine-Derived Peptides and Proteins: A Review

Fereidoon Shahidi and Abu Saeid

Marine Drugs, 2025, 23, 157
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Effect of the Type of Enzyme and Degree of Hydrolysis on the Antioxidant Properties of Paste Shrimp Protein Hydrolysates Prepared by Varying in Vitro Enzymatic Process

Vignaesh Dhanabalan, K. A. Martin Xavier, Kasturi Chattopadhyay, Kurukkan Kunnath Asha, Amjad K. Balange, L. N. Murthy and Binaya Bhushan Nayak

ACS Food Sci. Technol., 2025, 5, 1124
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Selenium Nanoparticles Decorated With Stevioside Potentially Attenuate Fructose Palmitate Induced Lipid Accumulation in HepG2 Cells

Shuai Li, Hui Yang, Wenjun Zhou, Ruoting Wang, Likang Li, Changfa Zhang, Jingyi Zhang, Yingxin Liu, Zhi Huang, Guowei Li and Mirella Giovarelli

Mediators of Inflammation, 2025, 2025
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Green preparation of low-molecular-weight galactomannan from Gleditsia sinensis and mechanistic investigation on ameliorating nonalcoholic fatty liver disease

Chi Feng, Xichuang Cheng, Mula Na, Fenglun Zhang, Jiufang Duan, Li Ji and Jianxin Jiang

Food Research International, 2025, 201, 115647
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Bioactive Peptides from Skipjack Tuna Cardiac Arterial Bulbs (II): Protective Function on UVB-Irradiated HaCaT Cells through Antioxidant and Anti-Apoptotic Mechanisms

Jing Kong, Xiao-Meng Hu, Wei-Wei Cai, Yu-Mei Wang, Chang-Feng Chi and Bin Wang

Marine Drugs, 2023, 21, 105
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Marine Bioactive Peptides—Structure, Function and Application

Chang-Feng Chi and Bin Wang

Marine Drugs, 2023, 21, 275
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Investigation of functional, antioxidant, anti-inflammatory, and antidiabetic properties of legume seed protein hydrolysates

Taiwo Scholes Adewole, Michael Chukwuemeka Bieni, Gbenga Emmanuel Ogundepo, Oludele Olayemi Odekanyin and Adenike Kuku

Food Hydrocolloids for Health, 2024, 5, 100175
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Blue mussel (Mytilus edulis) hydrolysates attenuate oxidized-low density lipoproteins (ox-LDL)-induced foam cell formation, inflammation, and oxidative stress in RAW264.7 macrophages

Chathuri Kaushalya Marasinghe, Soon-Do Yoon and Jae-Young Je

Process Biochemistry, 2023, 134, 131
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Blue Mussel-Derived Bioactive Peptides PIISVYWK (P1) and FSVVPSPK (P2): Promising Agents for Inhibiting Foam Cell Formation and Inflammation in Cardiovascular Diseases

Chathuri Kaushalya Marasinghe and Jae-Young Je

Marine Drugs, 2024, 22, 466
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Purification and Molecular Docking Study on the Angiotensin I-Converting Enzyme (ACE)-Inhibitory Peptide Isolated from Hydrolysates of the Deep-Sea Mussel Gigantidas vrijenhoeki

Seong-Yeong Heo, Nalae Kang, Eun-A Kim, Junseong Kim, Seung-Hong Lee, Ginnae Ahn, Je Hyeok Oh, A Young Shin, Dongsung Kim and Soo-Jin Heo

Marine Drugs, 2023, 21, 458
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Protein hydrolysates derived from superworm (Zophobas morio): Composition, bioactivity, and techno-functional properties

Alan Carvalho de Sousa Araujo, Andressa Coimbra Pereira, Robson Matheus Marreiro Gomes, Juan Rafael Buitrago Ramirez, Karoline da Silva Noda, Luan Gustavo Santos, Juliana Machado Latorres, Daniela Fernandes Ramos, José María Monserrat and Vilásia Guimarães Martins

International Journal of Biological Macromolecules, 2025, 295, 139668
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Revealing Novel Angiotensin‐Converting Enzyme (ACE)‐Inhibitory Peptides From Mackerel Hydrolysates and Potential Antihypertensive Mechanism Using Virtual Screening and Network Pharmacology Analysis

Hui Zhang, Chenxu Wang, Fang Wang, Xinyu Zhang, Yue Wang, Youping Xie, Baobei Wang and Zong‐Ping Zheng

Journal of Food Science, 2025, 90
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High Fischer ratio oligopeptides from hard-shelled mussel: Preparation and hepatoprotective effect against acetaminophen-induced liver injury in mice

Shuo-Lei Zheng, Yue-Zheng Wang, Yu-Qin Zhao, Chang-Feng Chi, Wang-Yu Zhu and Bin Wang

Food Bioscience, 2023, 53, 102638
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Valorization of Hakka Huangjiu lees: Optimization of ultrasound-assisted enzymatic extraction and identification of angiotensin I-converting enzyme inhibitory peptides

Shuchun Yang, Hong Wang, Weidong Bai, Wenhong Zhao, Gongliang Liu and Xiaoyan Liu

Food and Bioproducts Processing, 2024, 146, 77
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Mining of antioxidant sesquiterpene lactones from the aerial parts of Saussurea involucrata with feature-based molecular network strategy

Bodou Zhang, Lianting Liang, Jingwen Zhao, Sheng Li, Yong Sun, Lijun Fu, Xiumin Zhang, Wenyi Kang and Yu Zhang

Bioorganic Chemistry, 2025, 154, 108067
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Targeting the Cardiovascular-Alzheimer’s Disease Axis: The Promise of Marine Bioactive Peptides

Chathuri Kaushalya Marasinghe, Kumju Youn, Chi-Tang Ho and Mira Jun

Marine Drugs, 2026, 24, 56
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Screening and Antioxidant Activities Evaluation of Peptides From Abalone (Haliotis discus hannai Ino)

Jingna Wu, Xiaoya Wang, Kun Qiao, Nan Pan, Xiaoting Chen, Zhiyu Liu and Yuanxin Chen

Food Science & Nutrition, 2025, 13
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DPP-IV Inhibitory Peptides from Coix Seed Prolamins: Release, Identification, and Analysis of the Interaction between Key Residues and Enzyme Domains

Shu Zhang, Zhi-ming Li, Yuchao Feng, Shibo Yu, Zhijiang Li, Dongjie Zhang and Changyuan Wang

J. Agric. Food Chem., 2023, 71, 14575
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Potential Antioxidant Activity of Novel Antioxidant Peptides from Protein Hydrolysate of Peony Seed Dreg in Chemical and H2O2-Induced RAW264.7 Cells

Cuiling Wu, Chenxia Ren, Lianyun Zhang, Yingda Song, Huifang Gao and Kandi Sridhar

Journal of Food Biochemistry, 2023, 2023, 1
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Novel angiotensin-converting enzyme inhibitory peptides from tuna byproducts—milts: Preparation, characterization, molecular docking study, and antioxidant function on H2O2-damaged human umbilical vein endothelial cells

Shi-Kun Suo, Shuo-Lei Zheng, Chang-Feng Chi, Hong-Yu Luo and Bin Wang

Front. Nutr., 2022, 9
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Identification of angiotensin‐converting enzyme inhibitory peptides from peanut meal (Arachis hypogaea Linn) fermented by Lactobacillus pentosus using MALDI‐TOF–MS and LC–MS/MS

Wenjun Li, Yexia Guan, Lin Shi, Yang Chen, Huang Huang, Haiyin Zhen, Ping Wu, Chao Wang, Qian Wu and Wei Li

Food Frontiers, 2024, 5, 820
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Marine-Derived Bioactive Proteins and Peptides: A Review of Current Knowledge on Anticancer Potentials, Clinical Trials, and Future Prospects

Emmanuel Sunday Okeke, Innocent Uzochukwu Okagu, Kingsley Chukwudozie, Tobechukwu Christian Ezike and Timothy Prince Chidike Ezeorba

Natural Product Communications, 2024, 19
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Isolation, identification and in silico analysis of two novel cytoprotective peptides from tilapia skin against oxidative stress-induced ovarian granulosa cell damage

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