Nanozymes: new strategy for the management drug-induced acute liver injury

Minrui Kan, Yanan Wang, Nan Cheng, Kunlun Huang and Xiaoyun He

J. Mater. Chem. B, 2025, 13, 9023
DOI: 10.1039/D5TB00448A

Engineering inorganic nanozyme architectures for decomposition of reactive oxygen species

Tibor G. Halmagyi, Laila Noureen, Adél Szerlauth and Istvan Szilagyi

Dalton Trans., 2024, 53, 14132
DOI: 10.1039/D4DT01874E

Visualization of therapeutic intervention for acute liver injury using low-intensity pulsed ultrasound-responsive phase variant nanoparticles

You Yang, Ju-ying Zhang, Zi-jun Ma, Shi-chun Wang, Ping He, Xiao-qing Tang, Chao-feng Yang, Xia Luo, Xing Yang, Ling Li, Mao-chun Zhang, Yang Li and Jin-hong Yu

Biomater. Sci., 2024, 12, 1281
DOI: 10.1039/D3BM01423A

Recent advances in Prussian blue-based photothermal therapy in cancer treatment

Kaiyuan Tang, Xiao Li, Yanling Hu, Xiaonan Zhang, Nan Lu, Qiang Fang, Jinjun Shao, Shengke Li, Weijun Xiu, Yanni Song, Dongliang Yang and Junjie Zhang

Biomater. Sci., 2023, 11, 4411
DOI: 10.1039/D3BM00509G

Insights into the mechanism of a substituted metal center regulating the enzymatic activity of Prussian blue analogues for catalytic antioxidation

Genxiu Zhou, Qingrong Dong, Zhi Li, Feifei Yang, Xiaomei Shen, Quan Liu, Ge Fang and Cuicui Ge

Nanoscale, 2024, 16, 21039
DOI: 10.1039/D4NR02142H

Papain functionalized Prussian blue nanozyme colloids of triple enzymatic function

Attila Voros, Tibor G. Halmagyi, Szilard Saringer, Viktoria Hornok and Istvan Szilagyi

Chem. Commun., 2024, 60, 13032
DOI: 10.1039/D4CC04599H

Research progress on the synthesis, performance regulation, and applications of Prussian blue nanozymes

Yiyang Wang, Lei Gao, Yue Cao, Duanfeng Yan, Rilwanu Lukman, Jingxi Zhang, Quan Li, Jiaying Liu, Fengyi Du and Li Zhang

International Journal of Biological Macromolecules, 2025, 295, 139535
DOI: 10.1016/j.ijbiomac.2025.139535

Templated Synthesis of Hollow RuO2 Nanospheres for Alleviating Metal Wear Particle‐Induced Osteoclast Activation and Bone Loss

Ziying Sun, Faheem Muhammad, Chenfeng Qiao, Wenli Gong, Zheng Wang, Yuan Liu, Xin Yu, Jian Dong, Jie Lv, Xi Cheng, Zhihao Lu, Chenguang Lin, Zhongyang Lv, Wenshuang Sun, Tao Yuan, Jia Meng, Rui Wu, Dongquan Shi, Hui Wei and Nirong Bao

Small, 2025, 21
DOI: 10.1002/smll.202406210

Advanced Nanomedicines for Treating Refractory Inflammation-Related Diseases

Xiuxiu Wang, Xinran Song, Wei Feng, Meiqi Chang, Jishun Yang and Yu Chen

Nano-Micro Lett., 2025, 17
DOI: 10.1007/s40820-025-01829-7

Reactive oxygen species-scavenging nanoantioxidants in inflammation: Design and therapy

Jianqin Yan, Fei Sun, Min Wang and Xianwen Wang

Acta Biomaterialia, 2026, 212, 18
DOI: 10.1016/j.actbio.2025.12.046

Prussian blue nanotechnology in the treatment of spinal cord injury: application and challenges

XiaoPeng Gu, SongOu Zhang and WeiHu Ma

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1474711

Size and crystallinity effects on enzymatic activity and anti-inflammatory properties of cysteine-assisted Prussian blue nanozymes

Yilin He, Alberto Bianco and Cécilia Ménard-Moyon

Journal of Colloid and Interface Science, 2025, 679, 930
DOI: 10.1016/j.jcis.2024.10.008

The Protective Effect and Mechanism of a Phytochemical Extract from the Wild Vegetable Shutou (Crateva unilocularis Buch.) against Acetaminophen-Induced Liver Injury in Mice

Meimei Shan, Qian Ma, Yilin Sun, Fengyi Gao and Shengbao Cai

Foods, 2023, 12, 3109
DOI: 10.3390/foods12163109

Reactive Oxygen Species Scavenging Nanozymes: Emerging Therapeutics for Acute Liver Injury Alleviation

Tao Sun, Shilin Xiao, Miaomiao Wang, Qian Xie, Liang Zhang, Mingfu Gong, Dong Zhang and Chunyu Zhou

IJN, 2023, Volume 18, 7901
DOI: 10.2147/IJN.S435544

Tungsten disulfide atomic crystals with RONS scavenging and liver targeting capabilities for acetaminophen-induced acute liver injury therapy

Ziwen Xiao, Yu Liu, Zhenchao Tao, Yu Zhang, Qian Chen, Zhaohua Miao, Zhengbao Zha, Yan Ma, Hua Wang and Deyan Gong

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03771-7

Prussian blue nanoparticles coated with tumor cell membranes for precise photothermal therapy and subsequent inflammation reduction

Hairong Zou, Hui Wang, Yu Zhong, Zhijun Zhang, Zhigang Wang and Tingting Shang

Biochemical and Biophysical Research Communications, 2024, 723, 150173
DOI: 10.1016/j.bbrc.2024.150173

Endogenous stimuli-responsive drug delivery nanoplatforms for kidney disease therapy

Hufeng Fang, Shan Xu, Yu Wang, Hao Yang and Dan Su

Colloids and Surfaces B: Biointerfaces, 2023, 232, 113598
DOI: 10.1016/j.colsurfb.2023.113598

Polydopamine-Cloaked Nanoarchitectonics of Prussian Blue Nanoparticles Promote Functional Recovery in Neonatal and Adult Ischemic Stroke Models

Yijing Zhao, Cong Song, Haijun Wang, Chengcheng Gai, Tingting Li, Yahong Cheng, Junjie Liu, Yan Song, Qian Luo, Bing Gu, Weiyang Liu, Liwei Chai, Dexiang Liu and Zhen Wang

Biomater Res, 2024, 28
DOI: 10.34133/bmr.0079

Designing nanozymes for in vivo applications

Ruofei Zhang, Bing Jiang, Kelong Fan, Lizeng Gao and Xiyun Yan

Nat Rev Bioeng, 2024, 2, 849
DOI: 10.1038/s44222-024-00205-1

Polypyrrole nanozymes with cell-free DNA scavenging and ferroptosis inhibition capabilities for the treatment of acetaminophen-induced acute liver injury

Yu Liu, Ziwen Xiao, Yu Zhang, Qian Chen, Siyu Luo, Yaoqing Wang, Zhaohua Miao, Zhenchao Tao and Deyan Gong

Acta Biomaterialia, 2026
DOI: 10.1016/j.actbio.2026.03.030

Macrophage Membrane-Cloaked ROS-Responsive Albumin Nanoplatforms for Targeted Delivery of Curcumin to Alleviate Acute Liver Injury

Dandan Hu, Zhenqiu Huang, Wenlong Li, Lianhai Shan, Ming-yu Wu, Shun Feng and Yu Wan

Mol. Pharmaceutics, 2025, 22, 771
DOI: 10.1021/acs.molpharmaceut.4c00808

Development of Efficient Sodium Alginate/Polysuccinimide-Based Hydrogels as Biodegradable Acetaminophen Delivery Systems

Long Toan Trinh, Saebin Lim, Hyun Jong Lee and Il Tae Kim

Gels, 2023, 9, 980
DOI: 10.3390/gels9120980

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou and Chao Lu

Advanced Science, 2026, 13
DOI: 10.1002/advs.202509079