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“On-water” defluorophosphorylation of trifluoromethylated enones with phosphine oxides

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Defluorinative functionalization of perfluoroalkyl alkenes with ureas: synthesis of C4-perfluoroalkenyl 2-imidazolones

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Electrochemical trifluoromethylation of alkenyl oximes for the synthesis of isoxazolines and cyclic nitrones via radical annulation

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HP(O)Ph2/H2O-promoted hydrodefluorination of trifluoromethyl alkenes

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Green Chem., 2022, 24, 2777
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Chemo-, regio-, and stereoselective tetrafunctionalization of fluoroalkynes enables divergent synthesis of 5-7-membered azacycles

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Water-promoted defluorinative synthesis of fluoroalkylated 1,5-diazapentadienes by using (NH4)2CO3 as an NH2 and NH source

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Green Chem., 2023, 25, 9672
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Recent advances in N-heterocyclic carbene (NHC)-catalyzed fluorination and fluoroalkylation

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Four-component defluorinative reaction of allylic fluorides, amidines, and Cs2CO3under transition-metal-free conditions

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Green Chem., 2022, 24, 6816
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Photocatalytic fluoroalkyl radical-initiated construction of fluorinated heterocycles: mechanisms and applications

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Transition-metal-catalyzed asymmetric defluorinative reactions

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Sustainable defluorination pathway: from perfluoro gem diol hydration to electrocatalytic removal of CF3 at room temperature

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A general Fe-catalysed azidation of iododifluoroketones and its utilization for the synthesis of gem-difluoromethylenated triazoles

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Divergent Construction of Thiochromanes and N-Arylbutanamides via Arylthiodifluoromethyl Radical-Triggered Cascade of Alkenes

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Three-Component Sulfonylation and Heteroannulation Enabled by 3-Fold Defluorofunctionalization of Trifluoromethyl Enones

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Perfluoroalkyl Editing of Fluoroalkynes: Chemo-, Regio-, and Stereoselective Synthesis of (E)-(2-Amino-fluoroalkenyl)pyrimidines

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Difluorocarbene-Triggered Acyl Rearrangement Reaction: A Strategy for the Direct Introduction of the gem-Difluoromethylene Group

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Dual Role of (NH4)2CO3 Enables Defluorinative Synthesis of β-Fluoroalkylated Aminovinyl Ketones

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Experimental and computational journey on transition-metal-catalyzed C H functionalization with fluorinated π-systems

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Modular Synthesis of Furans with Four Nonidentical Substituents by Aqueous Defluorinative Reaction of Trifluoromethyl Enones with Two Nucleophiles

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Difluorinated Silyl Enol Ethers as Fluorine-Containing Building Blocks for the Synthesis of Organofluorine Compounds

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Chinese Journal of Organic Chemistry, 2022, 42, 3562
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Palladium-catalyzed ring-opening defluorinative cross-coupling of gem‑difluorocyclopropanes with fluoromalonates or fluorobis(phenylsulfonyl)methane

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Transition‐Metal‐Free Carbonyl Reduction and Hydrodefluorination of β‐Trifluoromethyl Enones with Hydrosilanes: Synthesis of gem‐Difluorovinyl Alcohols

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Eur J Org Chem, 2024, 27
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1,2‐Dichloroethane‐Assisted Defluorinative Ring‐Opening Reaction of DABCO and Polyfluoroalkyl Peroxides: Synthesis of Fluorinated N‐Ethyl Piperazines

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Construction of Fused Azacyclic Systems via Cascade Cyclizations of Vinyl Sulfonium Salts

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Catalytic and Chemodivergent Synthesis of 1-Substituted 9H-Pyrrolo[1,2-a]indoles via Annulation of β-CF3 Enones with 3-Substituted Indoles

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Chemo‐, Stereo‐ and Regioselective Fluoroallylation/Annulation of Hydrazones with gem‐Difluorocyclopropanes via Tunable Palladium/NHC Catalysis

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Thermal hydrolysis-induced molecular transformations in sludge: Implications for photochemical reactivity and dissolved antibiotics photodissipation

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Single-site modification of the P450-BM3 substrate-entrance facilitates the synthesis of optically pure pharmaceutically useful methyl trans-3-phenylglycidates

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Combining Hydrodefluorination and Defluorophosphorylation for Chemo- and Stereoselective Synthesis of gem-Fluorophosphine Alkenes

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Transition-metal-free defluorinative cyclization of perfluoroalkyl alkenyl iodides with C,N-dinucleophiles: Synthesis of (E)-perfluoroalkenyl pyrroles

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Green Synthesis and Catalysis, 2024
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Sulfinate-Promoted Defluorinative Cyclization of Polyfluoroalkyl Tetralones Enabled by Photocatalysis

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Switchable Multicomponent Cyclization Reactions to Access Fluoroalkylated Dihydropyrimidines and Pyrimidines under Solvent‐Free Conditions

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Divergent and Selective Synthesis of Functionalized Fluoroalkenes through Switchable Photocatalytic Dialkylation/Cyclization of Alkenes

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Tandem defluorination/annulation of α-CF3 carbonyls with bis-nucleophiles: Stereodivergent synthesis of 2-alkylidene-1,3-heterocycles

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Tetrahedron Letters, 2022, 100, 153902
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Water-Involved 1,3-Aminoxylation of Fluoroalkenes: Chemo-, Regio-, and Stereoselective Synthesis of β-Fluoroacyl Vinylamines

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Palladium‐Catalyzed Ring‐Opening/Defluorinative Annulation of gem‐Difluorocyclopropanes With β‐Keto Sulfones: Synthesis of Multi‐Substituted Furans

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Chemistry A European J, 2026
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Transition-Metal Free Synthesis of Cyclopropanone Ketals via Double Defluorinative Alkoxylation of gem-Difluorinated Cyclopropanes

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(E)-Selective Defluorinative Diphenothiazination of Trifluoromethyl Styrenes

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Na2S·9H2O Enabled Defluorodisulfuration and Hydrodefluorination of Perfluorobutyl Tetralones: Synthesis of Trifluoromethyl 1,2-Dithioles

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Highly Regioselective Synthesis of N‐β‐trifluoromethyl 2‐pyridones via anti‐Markovnikov Hydroamination of α‐(trifluoromethyl)styrenes with 2‐pyridones

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Chemistry An Asian Journal, 2023, 18
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Bulky and electron-rich Pd/NHC catalyzed Z-selective defluoroarylation of gem-difluorocyclopropanes under mild conditions

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Silver-Promoted Three-Component Synthesis of Perfluoroalkenyl Pyrroles through Partial Defluorinative Functionalization of Perfluoroalkyl Halides

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Efficient cyanation of amides and thioamides via difluorocarbene-mediated dehydration and desulfurization

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Chemo‐, Stereo‐ and Regioselective Fluoroallylation/Annulation of Hydrazones with gem‐Difluorocyclopropanes via Tunable Palladium/NHC Catalysis

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Controllable Synthesis of Trifluoromethyl- or gem-Difluorovinyl-containing Analogues of Neonicotinoids by the Reaction of α-(Trifluoromethyl)styrenes with 2-Nitroimino-imidazolidine

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Catalytic Diversification of gem‐Difluorocyclopropanes: Recent Advances and Challenges

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Electrochemical or Photoelectrochemical Alkenylpolyfluoroalkylation of 3-Aza-1,5-dienes: Regioselective Entry to Polyfluoroalkylated 4-Pyrrolin-2-ones

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Transition-Metal-Free Hydrodefluoroamination of Trifluoromethyl Enones for the Synthesis of α-Fluoroenamides

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Primary Amination of Enones Using Inorganic Ammonium Salts and Nitrogen Isotope Incorporation

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Electrochemically Promoted Trifluoromethylation/Cyclization for the Synthesis of Isoxazoles and Phosphoramide Compounds Bearing Trifluoromethyl

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Picking Two out of Three: Defluorinative Annulation of Trifluoromethyl Alkenes for the Synthesis of Monofluorinated Carbo‐ and Heterocycles

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The Chemical Record, 2024, 24
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[4+2] Defluorocycloaddition of Perfluoroalkyl Alkynes and Benzylamines: Synthesis of meta-Fluoroalkylated Pyridin-4-amines

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Transition‐Metal‐Free Dehalogenative 1,2‐Dichalcogenation of Internal Fluoroalkyl Alkenes

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Cryogenic Organometallic Carbon–Fluoride Bond Functionalization with Broad Functional Group Tolerance

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Photoredox Decarboxylative 3‐Fluoroallylation of α‐Amino Acids

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