Resurgence and advancement of photochemical hydrogen atom transfer processes in selective alkane functionalizations

Liang Chang, Shun Wang, Qing An, Linxuan Liu, Hexiang Wang, Yubo Li, Kaixuan Feng and Zhiwei Zuo

Chem. Sci., 2023, 14, 6841
DOI: 10.1039/D3SC01118F

Photocatalytic C(sp3) radical generationviaC–H, C–C, and C–X bond cleavage

Chia-Yu Huang, Jianbin Li and Chao-Jun Li

Chem. Sci., 2022, 13, 5465
DOI: 10.1039/D2SC00202G

Regiodivergent sulfonylarylation of 1,3-enynes via nickel/photoredox dual catalysis

Ya Chen, Kun Zhu, Qingqin Huang and Yixin Lu

Chem. Sci., 2021, 12, 13564
DOI: 10.1039/D1SC04320J

S-Trifluoromethyl thioesters as bifunctional reagents for acyl-trifluoromethylthiolation of alkenes and 1,3-enynesviaphotoredox/copper dual catalysis

Zhong Zhang, Yang Tian, Xiaowei Li, Zemin Wang, Ruihua Liu, Ping Chen, Xiangqian Li, Jiajia Dai and Dayong Shi

Green Chem., 2023, 25, 2723
DOI: 10.1039/D3GC00266G

Visible-light-promoted C(sp3)–H thiolation of aliphatic ethers with thiosulfonates

Wen-Zhu Bi, Qing-Pu Liu, Chen-Yu Li, Wen-Jie Zhang, Su-Xiang Feng, Yang Geng, Xiao-Lan Chen and Ling-Bo Qu

New J. Chem., 2023, 47, 9035
DOI: 10.1039/D3NJ01029E

A Cu/Cd-cocatalysed cascade reaction for constructing nitrogen-tethered 1,6-enynes enabled by 1,5-hydride transfer

Tiantian Zhang, Hexiang Wang, Liliang Huang, Junhai Huang and Huangdi Feng

Org. Chem. Front., 2025, 12, 3856
DOI: 10.1039/D5QO00174A

Photo-induced 1,2-alkylarylation/cyclization of alkenes, alkyl halides and N-alkylindoles via an EDA-complex

Tao Ju, Min Ge, Li-Hang Ren, Ai-Ling Lu, Zhi-Hao Wang, Shi-Ji He, Jing Sun, Ying Han and Chao-Guo Yan

Org. Chem. Front., 2024, 11, 1412
DOI: 10.1039/D3QO01908J

Multicomponent reactions and photo/electrochemistry join forces: atom economy meets energy efficiency

Guglielmo A. Coppola, Serena Pillitteri, Erik V. Van der Eycken, Shu-Li You and Upendra K. Sharma

Chem. Soc. Rev., 2022, 51, 2313
DOI: 10.1039/D1CS00510C

Merging cobalt and photoredox catalysis for the C8–H alkoxylation of 1-naphthylamine derivatives with alcohols

Zhaoliang Xu, Yu Hu, Lei Wang, Mingli Sun and Pinhua Li

Org. Biomol. Chem., 2021, 19, 10112
DOI: 10.1039/D1OB01721G

Metal-free stereoselective intramolecular oxyamination of alkynes using a robotic and rapid photocatalytic synthesis and screening system

Jia-Min Lu, Yihui Mao, Qihang Guo, Chengcheng Zhong, Xian-Ge Gao, Qun Fang and Zhan Lu

Green Chem., 2025, 27, 560
DOI: 10.1039/D4GC05100A

Visible-light-induced metal-free coupling of C(sp3)–H sources with heteroarenes

Anogh Ghosh, Pranjal Pyne, Sumit Ghosh, Debashis Ghosh, Souvik Majumder and Alakananda Hajra

Green Chem., 2022, 24, 3056
DOI: 10.1039/D1GC04384F

An electrochemical multicomponent cascade annulation and functionalization reaction to enable C(sp3)–H trifluoromethylation

Yuxin Ding, Hao Zhang, Dingyuan Lou, Wenkai Huang, Yuan Shi, Hongmei Luo, Changjun Zhang and Yuanyuan Xie

Org. Chem. Front., 2024, 11, 1662
DOI: 10.1039/D3QO01684F

A cobalt covalent organic framework: a dual-functional atomic-level catalyst for visible-light-driven C–H annulation of amides with alkynes

Jingwen Jia, Xiubin Bu and Xiaobo Yang

J. Mater. Chem. A, 2022, 10, 11514
DOI: 10.1039/D2TA01325H

Redox-neutral synthesis of π-allylcobalt complexes from alkenes for aldehyde allylation via photoredox catalysis

Dandan Zhang, Haoyu Li, Zhuowen Guo, Yuqing Chen, Huaipu Yan, Zenghui Ye, Fengzhi Zhang, Binghui Lu, Erjun Hao and Lei Shi

Green Chem., 2022, 24, 9027
DOI: 10.1039/D2GC02990A

Catalytic three-component carboamination of unactivated alkenes with primary sulfonamides

Ying Zhang, Kai-Dian Li, Chang-Quan Zhou, Zhi-Xi Xing and Huan-Ming Huang

Green Chem., 2024, 26, 10434
DOI: 10.1039/D4GC02879A

Recent advances in C(sp3)–N bond formation via metallaphoto-redox catalysis

Juan Zhang, Xiao-Die Huan, Xin Wang, Guo-Qing Li, Wen-Jing Xiao and Jia-Rong Chen

Chem. Commun., 2024, 60, 6340
DOI: 10.1039/D4CC01969E

Recent advances in dual photoredox/nickel catalyzed alkene carbofunctionalised reactions

Anilkumar Kommoju, Kattamuri Snehita, Kandi Sowjanya, Saratchandra Babu Mukkamala and Kishor Padala

Chem. Commun., 2024, 60, 8946
DOI: 10.1039/D4CC02914C

Photoinduced copper-catalyzed asymmetric radical three-component cross-coupling of 1,3-enynes with oxime esters and carboxylic acids

Guo-Qing Li, Fan-Rong Meng, Wen-Jing Xiao and Jia-Rong Chen

Org. Chem. Front., 2023, 10, 2773
DOI: 10.1039/D3QO00513E

Rhodium(ii)-incorporated metal–organic framework catalyst combined with flow chemistry for efficient carbene-mediated three-component reactions

Haiqing Wang, Hekun Huang, Xinke Zhang, Chunan Wang, Zhuodi Chen, Chengyong Su, Xiang Fu and Wenhao Hu

Org. Biomol. Chem., 2026, 24, 324
DOI: 10.1039/D5OB01742D

Fe-mediated oxidative cascade [1 + 2 + 3]-cyclization/esterification reaction: synthesis of 4-alkylated 1,4-dihydropyridines

Zhuoyuan Liu, Yulin Sun, Mingshuai Zhang, Longkun Chen, Xue-Bing Chen, Xiang Li and Fuchao Yu

Org. Biomol. Chem., 2023, 21, 5475
DOI: 10.1039/D3OB00704A

Photoinduced cobaloxime catalysis for allylic mono- and diphosphinylation of alkenes with hydrogen evolution

Aijun Zhang, Miao-Miao Li, Lei Guo, Huaixiang Yang, Jiefei Guo, Da Xu and Wei Ding

Org. Chem. Front., 2025, 12, 148
DOI: 10.1039/D4QO01638F

Visible-light-mediated radical difunctionalization of alkenes with aromatic aldehydes

Zhenhua Xu, Tao Geng, Jun Du, Youpeng Zuo, Xiaoxiao Hu, Lin Liu, Zhiqiang Shi and Huawen Huang

Org. Biomol. Chem., 2025, 23, 2625
DOI: 10.1039/D4OB02090A

Synthesis of trisubstituted hydroxylamines by a visible light-promoted multicomponent reaction

Bao-Gui Cai, Qian Li, Qiong Zhang, Lei Li and Jun Xuan

Org. Chem. Front., 2021, 8, 5982
DOI: 10.1039/D1QO01102B

The position-tuned nitrogen atom in Ni(ii)-metalated covalent organic frameworks enables highly efficient and sustainable C–N coupling

Rui Zhang, Jinyang Hai, Huiying Chen, Mingxiang Zhu and Fang Zhang

Green Chem., 2025, 27, 13311
DOI: 10.1039/D5GC03438H

Metallaphotoredox catalysis for sp3C–H functionalizations through hydrogen atom transfer (HAT)

Jingchang Zhang and Magnus Rueping

Chem. Soc. Rev., 2023, 52, 4099
DOI: 10.1039/D3CS00023K

Three-component 1,2-dicarbofunctionalization of alkenes involving alkyl radicals

Pin Gao, Yue-Jie Niu, Fan Yang, Li-Na Guo and Xin-Hua Duan

Chem. Commun., 2022, 58, 730
DOI: 10.1039/D1CC05730H

Three-component carboacylation of alkenes via cooperative nickelaphotoredox catalysis

Dingyi Wang and Lutz Ackermann

Chem. Sci., 2022, 13, 7256
DOI: 10.1039/D2SC02277J

Rapid construction of a polysubstituted “caged” oxa-bishomocubane framework from vinylidenecyclopropanes through a sequential dual catalysis of copper(i) and visible-light-induced photosensitization

Yan-Shun Zhang, Yin Wei and Min Shi

Org. Chem. Front., 2022, 9, 3739
DOI: 10.1039/D2QO00508E

Direct alkene functionalization via photocatalytic hydrogen atom transfer from C(sp3)–H compounds: a route to pharmaceutically important molecules

Hangqian Fan, Yuxin Fang and Jingbo Yu

Chem. Commun., 2024, 60, 13796
DOI: 10.1039/D4CC05026F

Intramolecular dehydrogenative amination of alkenes via dual organic photoredox and cobalt catalysis without a hydrogen acceptor

Wan-Lei Yu, Zi-Gang Ren, Wei Ma, Haixue Zheng, Wangsuo Wu and Peng-Fei Xu

Green Chem., 2022, 24, 6131
DOI: 10.1039/D2GC02084J

Recent Advances in Carbonyl‐Photoredox/Transition Metal Dual Catalysis

Da‐Liang Zhu, Jie Li, David James Young, Yanqing Wang and Hong‐Xi Li

Asian J Org Chem, 2023, 12
DOI: 10.1002/ajoc.202300275

One-Pot, Five-Component Condensation Reaction of Isatin, Secondary Amines, Malononitrile, Alcohols, and Molecular Oxygen to Access 3-Functionalized 2-Oxindoles

Kaushik Bora, Uma Devi Newar and Ram Awatar Maurya

J. Org. Chem., 2023, 88, 14216
DOI: 10.1021/acs.joc.3c01510

Visible‐Light Mediated Ugi‐Type Reaction for the Synthesis of 3,3‐Disubstituted Phthalides

Feiyu Gao, Chenxin Yin, Yi He, Shuang Zhao, Mengxiao Chen, Jia Zheng, Dan Ni, Houhua Yin, Xian Fu, Xiaoyong Zhang and Shenyou Nie

Adv Synth Catal, 2024, 366, 2728
DOI: 10.1002/adsc.202400040

Alkylcyanation of Unactivated Alkenes with Protic C(sp3)−H Feedstocks via Radical‐Initiated Intramolecular Cyano Group Migration Enabled by Photoredox/Brønsted Base Dual Catalysis

Yang Hong and Hong‐Ping Deng

ChemPhotoChem, 2025, 9
DOI: 10.1002/cptc.202400282

Ketone-Derived Pro-aromatic Reagents for Radical Group Transfer Reactions and Deconstructive Functionalizations

Shinje Miñoza, Ivy L. Librando and Hsuan-Hung Liao

Synlett, 2024, 35, 1072
DOI: 10.1055/a-2197-1909

Nickel-embedded covalent organic frameworks for dual photocatalytic hydrogen evolution and cross-coupling catalysis

Swati Jindal, Kuntal Pal, Mostafa Zeama, Partha Maity, Tian Jin, Mickaele Bonneau, Rajesh Kancherla, Omar F. Mohammed, Osama Shekhah, Magnus Rueping and Mohamed Eddaoudi

Chem, 2026, 12, 102751
DOI: 10.1016/j.chempr.2025.102751

Photoinduced Copper-Catalyzed Late-Stage Azidoarylation of Alkenes via Arylthianthrenium Salts

Yuan Cai, Sagnik Chatterjee and Tobias Ritter

J. Am. Chem. Soc., 2023, 145, 13542
DOI: 10.1021/jacs.3c04016

Construction of Tetrazole Derivatives via Sequential Ugi‐N3/Pd‐Catalyzed Isocyanide Insertion Reactions

Hao‐Jie Fan, A‐Ting Li, Jun Li, Zi‐Qi Du, Long Wang, Xian‐Min Zhou, Ping He and Zhi‐Lin Ren

ChemistrySelect, 2023, 8
DOI: 10.1002/slct.202204294

Synergistic Photoredox/Palladium Catalyzed Enantioconvergent Carboxylation of Racemic Heterobiaryl (Pseudo)Halides with CO2

Bihai Ye, Lei Su, Kaiting Zheng, Shen Gao and Jiawang Liu

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202413949

Mono- and dicarboxylation of alkenes with oxalate catalyzed by a spiro-NHC-Ir(III) photocatalyst system

Wen-Ping Xie, Zhi-Min Chen, Yi-Zhe Zhao, Heng Cai, Xu-Rui Liu, Yu-Bo Qiao, Qi-Long Chen, Tong-Mei Ding and Yong-Qiang Tu

Sci. China Chem., 2026, 69, 1873
DOI: 10.1007/s11426-025-2887-2

Synthesis of Homoallylic Amines by Radical Allylation of Imines with Butadiene under Photoredox Catalysis

Yuqing Chen, Huaipu Yan, Qian Liao, Dandan Zhang, Shuangjie Lin, Erjun Hao, Rukhsana Murtaza, Chenchen Li, Chao Wu, Chunying Duan and Lei Shi

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202204516

Benzocarbazole Synthesis via Visible-Light-Accelerated Rh(III)-Catalyzed C–H Annulation of Aromatic Amines with Bicyclic Alkenes

Yichun Wang, Deyang Jia, Jing Zeng, Yuming Liu, Xiubin Bu and Xiaobo Yang

Org. Lett., 2021, 23, 7740
DOI: 10.1021/acs.orglett.1c02709

Synergistic Photoredox/Palladium Catalyzed Enantioconvergent Carboxylation of Racemic Heterobiaryl (Pseudo)Halides with CO2

Bihai Ye, Lei Su, Kaiting Zheng, Shen Gao and Jiawang Liu

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202413949

Light-empowered contra-thermodynamic stereochemical editing

Peng-Zi Wang, Wen-Jing Xiao and Jia-Rong Chen

Nat Rev Chem, 2022, 7, 35
DOI: 10.1038/s41570-022-00441-2

Metallaphotoredox catalysis for sp3 C–H functionalizations through single-electron transfer

Jingchang Zhang and Magnus Rueping

Nat Catal, 2024, 7, 963
DOI: 10.1038/s41929-024-01215-3

Radical Cascade Reaction of Heterocyclic Ketene Aminals with Thiocyanates Promoted by Visible Light: Synthesis of Functionalized Fused 2-Iminothiazolines

Shu Yang, Ting-Ting Guo, Jian-Bo Ma, Hui-Ting Jia, Jin Liu and Sheng-Jiao Yan

J. Org. Chem., 2024, 89, 13678
DOI: 10.1021/acs.joc.4c01899

Photo‐Catalyzed Redox‐Neutral 1,2‐Dialkylation of Alkenes

Wen‐Hui Sun, Jian‐Yu Zou, Xiao‐Jing Xu, Jin‐Lin Wang, Mei‐Ling Liu and Xue‐Yuan Liu

Adv Synth Catal, 2022, 364, 2260
DOI: 10.1002/adsc.202200310

Towards a More Sustainable Photocatalyzed α‐Arylation of Amines: Green Solvents, Catalyst Recycling and Low Loading

Arianna Quintavalla, Davide Carboni, Cecilia Sepe, Liviana Mummolo, Nelsi Zaccheroni and Marco Lombardo

Adv Synth Catal, 2023, 365, 252
DOI: 10.1002/adsc.202201123

The Application Research on Cu-Al/Sba-15 Bimetallic Synergistic Effect in the C-X Bond Sequential Assembly

Mengyu Pei, Xianghao Luo, Quan Tang, Nianyu Huang and Long Wang

SSRN Journal, 2022
DOI: 10.2139/ssrn.4184986

Visible‐Light‐Induced Multicomponent Reaction of Aromatic Aldehydes, Amines and Sodium Difluoromethanesulfinate: Synthesis of CF2H‐Substituted Secondary Amines

Shanshan Zhang, Yang Geng, Jialong Jiao, Dapeng Zou, Yangjie Wu and Yusheng Wu

Adv Synth Catal, 2023, 365, 4132
DOI: 10.1002/adsc.202300822

Photomediated One-Pot Three-Component Approach Enables the Formal Direct N-Acylation/Sulfonylation and α-C–H Functionalization of 1,2,3,4-Tetrahydroisoquinoline

Yun Zhang, Zheng-Qian Zhang, Yao Du, Jia-Huan Nie, Yan Wang, Bao-Dong Cui, Xue-Qing Mou, Ming-Qiang Zhou and Yong-Zheng Chen

J. Org. Chem., 2024, 89, 11513
DOI: 10.1021/acs.joc.4c01229

Alkylcyanation of unactivated alkenes via photoinduced hydrogen atom transfer and 1,4-cyano migration

Meichen Xu, Pandaram Sakthivel, Zongyang Ma and Juntao Ye

Tetrahedron Letters, 2025, 159, 155516
DOI: 10.1016/j.tetlet.2025.155516

Visible‐Light‐Catalyzed N‐Radical‐Enabled Cyclization of Alkenes for the Synthesis of Five‐Membered N‐Heterocycles

Hui‐Zhi Wang, Jiao‐Zhe Li, Zhiyong Guo, Hongxing Zheng and Wen‐Ting Wei

ChemSusChem, 2021, 14, 4658
DOI: 10.1002/cssc.202101586

Visible-Light-Induced Energy-Transfer-Mediated Hydrofunctionalization and Difunctionalization of Unsaturated Compounds via Sigma-Bond Homolysis of Energy-Transfer Acceptors

Qiao Sun, Shao-Peng Wang, Yuan Xu, Aihua Yin, Liu Yang, Jingheng Zhu, Chun-Ling Zheng, Guowei Wang, Zheng Fang, Shanhong Sui, Daixi Wang, Yan Dong, Dongshun Zhang, Chang-Sheng Wang and Kai Guo

ACS Catal., 2025, 15, 1854
DOI: 10.1021/acscatal.4c07316

Electrochemical Difunctionalization of Alkenes

Jing-Hao Qin, Ning Nan and Jin-Heng Li

Synthesis, 2023, 55, 2843
DOI: 10.1055/a-2036-2074

Photobiocatalytic Reaction: From Single Component to Triple Components

Rui‐Tao Sun, Peng Chen, Sheng‐Zhen Xu, Liang‐Qiu Lu and Wen‐Jing Xiao

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202502489

Lewis Acid Catalyzed Three‐Component Carbofunctionalization of Styrenes with Diacyl Peroxides and Nucleophiles

Shuang‐Long Li, Ren Wang, Jiajie Chen, Hao Zhang, Gao‐Kai Hou, Xin Lu, Qing Sun and Yang Li

Adv Synth Catal, 2023, 365, 17
DOI: 10.1002/adsc.202200897

Recent Advances in the Synthesis of Amino Acid Derivatives through Multicomponent Reactions

Yue Wu, Tingwei Gu, Jing Zhao, Binbin Li and Leifeng Wang

Eur J Org Chem, 2025, 28
DOI: 10.1002/ejoc.202401299

Three-Component Cycloaddition Reaction of Aryne, Acrylate, and Imine Derivatives: Divergent Synthesis of Hexahydropyrrolo[1,2-a]quinolines and 1,4-Dihydroquinolines

Wenbo Cai, Xin Wang, Yanyan Zhu and Chuanjun Song

Org. Lett., 2025, 27, 11918
DOI: 10.1021/acs.orglett.5c03900

Highly Functional Allyl-Bicyclo[1.1.1]pentane Synthesis by Radical-Initiated Three-Component Stereoselective Allylation

Qian Zeng, Wangyu Shi and Arjan W. Kleij

JACS Au, 2025, 5, 913
DOI: 10.1021/jacsau.4c01129

Application of α-Keto Acids in Metal-Free Photocatalysis

Kunchen Xie, Mingxuan Jiang, Xiaolan Chen, Qiyan Lü and Bing Yu

Chinese Journal of Organic Chemistry, 2021, 41, 4575
DOI: 10.6023/cjoc202109008

Metallaphotoredox-enabled aminocarboxylation of alkenes with CO2

Jun-Ping Yue, Jin-Cheng Xu, Hai-Tian Luo, Xiao-Wang Chen, He-Xin Song, Yu Deng, Lihua Yuan, Jian-Heng Ye and Da-Gang Yu

Nat Catal, 2023, 6, 959
DOI: 10.1038/s41929-023-01029-9

Intermolecular Photocatalytic Chemo‐, Stereo‐ and Regioselective Thiol–Yne–Ene Coupling Reaction

Julia V. Burykina, Andrey D. Kobelev, Nikita S. Shlapakov, Alexander Yu. Kostyukovich, Artem N. Fakhrutdinov, Burkhard König and Valentine P. Ananikov

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202116888

Visible-Light-Driven Multicomponent Diamination and Oxyamination of Alkene

Mengping He, Chengcheng Shi, Mengqi Luo, Chao Yang, Lin Guo, Yating Zhao and Wujiong Xia

J. Org. Chem., 2024, 89, 1967
DOI: 10.1021/acs.joc.3c02690

Engaging Alkenes in Metallaphotoredox: A Triple Catalytic, Radical Sorting Approach to Olefin-Alcohol Cross-Coupling

Qinyan Cai, Iona M. McWhinnie, Nathan W. Dow, Amy Y. Chan and David W. C. MacMillan

J. Am. Chem. Soc., 2024, 146, 12300
DOI: 10.1021/jacs.4c02316

Theoretical Underpinning of Synergetic Ir/Cu-Metallaphotoredox Catalysis in Multicomponent C–N Cross-Coupling Reactions

Manoj V. Mane, Sayan Dutta, Luigi Cavallo and Bholanath Maity

ACS Catal., 2023, 13, 6249
DOI: 10.1021/acscatal.3c00567

Bottom‐Up Construction of Ni(II)‐Incorporated Covalent Organic Framework for Metallaphotoredox Catalysis

Hai‐Chao Hu, Zhi‐Peng Wang, Lin Liang, Xin‐Yu Du, Ting Li, Jie Feng, Tian‐Tian Xiao, Ze‐Ming Jin, San‐Yuan Ding, Qiang Liu, Liang‐Qiu Lu, Wen‐Jing Xiao and Wei Wang

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202303476

Copper‐Catalyzed[3 + 2 + 1] Cycloaddition of Alkenes with Benzoquinones and Dicarbonyl Compounds via Tandem Oxidative Dicarbofunctionalization/Cyclization Sequence

Tianxing Du, Song Li, Yunfei He, Huan Long, Xigong Liu, Hai‐Bei Li and Lei Liu

Chin. J. Chem., 2022, 40, 1681
DOI: 10.1002/cjoc.202200113

Decarboxylative Cross-Coupling Enabled by Fe and Ni Metallaphotoredox Catalysis

Reem Nsouli, Sneha Nayak, Venkadesh Balakrishnan, Jung-Ying Lin, Benjamin K. Chi, Hannah G. Ford, Andrew V. Tran, Ilia A. Guzei, John Bacsa, Nicholas R. Armada, Fedor Zenov, Daniel J. Weix and Laura K. G. Ackerman-Biegasiewicz

J. Am. Chem. Soc., 2024, 146, 29551
DOI: 10.1021/jacs.4c09621

Copper-Catalyzed Enantioselective Three-Component Carboamidation of Styrenes with Alkanes and Amides

Ying-Ying Chen, Ling Dai, Xuan-Ge Zhang and Qi-Lin Zhou

J. Am. Chem. Soc., 2025, 147, 12397
DOI: 10.1021/jacs.5c02348

Visible-Light-Induced Ru-Catalyzed Ortho C−H Diarylation of 2-Phenyl-2H-Indazoles and 1-Phenyl-1H-Pyrazoles

Sumit Ghosh, Asim Kumar Ghosh, Frenki Mahato, Abu Taher, Subrata Sinha and Alakananda Hajra

Synlett, 2026, 37, 212
DOI: 10.1055/a-2705-9302

Photoredox‐Induced Deaminative Radical‐Cationic Three‐Component Couplings with N‐Alkylpyridinium Salts and Alkenes

Paul Seefeldt, Rajesh Dasi, Alexander Villinger and Malte Brasholz

ChemPhotoChem, 2021, 5, 979
DOI: 10.1002/cptc.202100226

Catalytic Aldehyde–Alkyne Couplings Triggered by Ketyl Radicals

Zhi-Xi Xing, Shu-Sheng Chen and Huan-Ming Huang

Org. Lett., 2024, 26, 9949
DOI: 10.1021/acs.orglett.4c03802

Light-Driven N-Heterocyclic Carbene-Catalyzed Multi-Component Reaction for the Synthesis of β-Amino Ketones

Chengcheng Shi, Nan Zhong, Lin Guo, Jiawen Yin, Chao Yang and Wujiong Xia

Org. Lett., 2024, 26, 8848
DOI: 10.1021/acs.orglett.4c03288

Dihydroquinazolinones as adaptative C(sp3) handles in arylations and alkylations via dual catalytic C–C bond-functionalization

Xin-Yang Lv, Roman Abrams and Ruben Martin

Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-29984-0

Visible-Light-Mediated Multicomponent Synthesis of Azido-Substituted gem-Difluoroalkenes

Jiabin Shen, Du Hu, Yi Chen, Hao Xu, Donghao Wang, Kai Ge, Chao Shen and Min Wang

J. Org. Chem., 2026
DOI: 10.1021/acs.joc.6c00207

CF3SO2Na-Mediated Five-Component Carbonylation of Triarylboroxines with TMSCF3 and THF/LiOH/NaI to Give Aroyloxyalkyl Iodides

Wenjian Guan, Dong Lu, Xiaogang Yang, Wei Deng, Jiannan Xiang, Nobuaki Kambe and Renhua Qiu

J. Org. Chem., 2022, 87, 9635
DOI: 10.1021/acs.joc.2c00662

Photocatalytic vinyl radical-mediated multicomponent 1,4-/1,8-carboimination across alkynes and olefins/(hetero)arenes

Shan-Shan Li, Yu-Shi Jiang, Xue-Ling Luo, Xuming Ran, Yuqiang Li, Dong Wu, Cheng-Xue Pan and Peng-Ju Xia

Sci. China Chem., 2024, 67, 558
DOI: 10.1007/s11426-023-1812-x

Intermolecular Photocatalytic Chemo‐, Stereo‐ and Regioselective Thiol–Yne–Ene Coupling Reaction

Julia V. Burykina, Andrey D. Kobelev, Nikita S. Shlapakov, Alexander Yu. Kostyukovich, Artem N. Fakhrutdinov, Burkhard König and Valentine P. Ananikov

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202116888

A Highly Regioselective Three‐Component Radical Coupling of Alkenes with Carboxylic Acids and Their Derivatives

Bo Ling, Haonan Bai, Siwei Hu, Zhehan Liang, Hongliang Chen, Xianli Yang, Weipeng Li, Chengjian Zhu and Jin Xie

Chin. J. Chem., 2026
DOI: 10.1002/cjoc.70498

Extending Photocatalyst Activity through Choice of Electron Donor

Felicity Draper, Egan H. Doeven, Jacqui L. Adcock, Paul S. Francis and Timothy U. Connell

J. Org. Chem., 2023, 88, 6445
DOI: 10.1021/acs.joc.2c02460

Metallaphotoredox Enabled Single Carbon Atom Insertion into Alkenes for Allene Synthesis

Gang Liu, Zhaoxin Shi, Chuning Guo, Danyu Gu and Zhaobin Wang

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202418746

Enantioselective Copper-Catalyzed Fukuyama Indole Synthesis from 2-Vinylphenyl Isocyanides

Till Drennhaus, Dirk Leifert, Jessika Lammert, Jan Philipp Drennhaus, Klaus Bergander, Constantin G. Daniliuc and Armido Studer

J. Am. Chem. Soc., 2023, 145, 8665
DOI: 10.1021/jacs.3c01667

Dual Palladium‐Photoredox Catalyzed C−H functionalization

Partha Sarathi Saha and Purushothaman Gopinath

Eur J Org Chem, 2022, 2022
DOI: 10.1002/ejoc.202200733

Allenyl Radicals in Organic Synthesis: Challenges and Recent Advances

Yang Yu and Jitang Zhang

Eur J Org Chem, 2022, 2022
DOI: 10.1002/ejoc.202201017

Design, synthesis and biological evaluation of difluoroalkylated protoilludanes obtained by a practical radical cascade difluoroalkylation-cyclization reaction

Juan Fang, Tao Yang, Min An, Yingle Liu, Yi Liu, Yi Yang, Jie Zhou, Ting Cao, Qijun Ren and Hui Huang

Tetrahedron Letters, 2022, 89, 153594
DOI: 10.1016/j.tetlet.2021.153594

Green photocatalytic syntheses using water as solvent/hydrogen source/oxygen source

Wen-Tao Ouyang, Fang Xiao, Li-Juan Ou and Wei-Min He

Current Opinion in Green and Sustainable Chemistry, 2023, 40, 100760
DOI: 10.1016/j.cogsc.2023.100760

Photoredox/Nickel Dual-Catalytic Asymmetric Silylarylation of Alkenes

Qiyang Yuan, Zhengrong Deng, Yi Wan and Yongqiang Zhang

Org. Lett., 2025, 27, 680
DOI: 10.1021/acs.orglett.4c04570

Bifunctional Copper Metal–Organic Framework Catalyst for Late-Stage Functionalization of Alkenes

Lu Dong, Hu Chen, Xiaoli Tan, Ning Zhang, Wei Sun, Dechao Li, Guangchao Liang, Yanyuan Jia and Shuo Guo

ACS Catal., 2025, 15, 4198
DOI: 10.1021/acscatal.5c00755

Controllable Radical Reactions of 1,3-Dienes with Light

Shiwei Lü and Jin Xie

ACS Catal., 2025, 15, 7749
DOI: 10.1021/acscatal.5c01867

Three-Component Aminoheteroarylation of Alkenes via Photoinduced EDA Complex Activation

Chengcheng Shi, Lin Guo, Han Gao, Mengqi Luo, Xiao Zhou, Chao Yang and Wujiong Xia

Org. Lett., 2023, 25, 7661
DOI: 10.1021/acs.orglett.3c02988

Synthesis of Homoallylic Amines by Radical Allylation of Imines with Butadiene under Photoredox Catalysis

Yuqing Chen, Huaipu Yan, Qian Liao, Dandan Zhang, Shuangjie Lin, Erjun Hao, Rukhsana Murtaza, Chenchen Li, Chao Wu, Chunying Duan and Lei Shi

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202204516

Recent Advances on Catalytic Asymmetric Synthesis of Molecules Bearing a Fluorine-Containing Stereogenic Carbon Center (2015–2024)

Subarna Jyoti Kalita, Jing Qi, Lu Xiao, Debarshi Saha, Yi-Yong Huang and Norio Shibata

Chem. Rev., 2025, 125, 8477
DOI: 10.1021/acs.chemrev.5c00177

Recent advances in copper-catalyzed multicomponent reactions with photoinduction

Liangliang Song, Lingchao Cai, Erik V. Van der Eycken and Lei Gong

Coordination Chemistry Reviews, 2025, 528, 216428
DOI: 10.1016/j.ccr.2024.216428

Photoredox‐mediated Multicomponent Reactions

Pooja Yadav, A. Anagha Varma, A. J. Punnya and Purushothaman Gopinath

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202200390

Metallaphotoredox Enabled Single Carbon Atom Insertion into Alkenes for Allene Synthesis

Gang Liu, Zhaoxin Shi, Chuning Guo, Danyu Gu and Zhaobin Wang

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202418746

Photocatalytic Selective Synthesis of Hemiketals from Alkenes, α-Halo Acylarenes, and Water via N-Methylindole Catalysis

Tao Ju, Zhi-Cheng Wei, Min Ge, Ying-Ying Ma, Sheng Huang, Jing Sun, Qiang Fu, Ying Han and Chao-Guo Yan

Org. Lett., 2026, 28, 2711
DOI: 10.1021/acs.orglett.6c00192

Elaborating azaaryl alkanes enabled by photoredox/palladium dual catalyzed dialkylation of azaaryl alkenes

Yunqiang Li, Yongxian Huang, Sinuo Li, He Huang and Zhiwei Jiao

Chinese Chemical Letters, 2025, 36, 110051
DOI: 10.1016/j.cclet.2024.110051

Nickel-catalysed enantioselective alkene dicarbofunctionalization enabled by photochemical aliphatic C–H bond activation

Xia Hu, Iván Cheng-Sánchez, Wangqing Kong, Gary A. Molander and Cristina Nevado

Nat Catal, 2024, 7, 655
DOI: 10.1038/s41929-024-01153-0

Cu-Catalyzed Asymmetric Three-Component Radical Acylarylation of Vinylarenes with Aldehydes and Aryl Boronic Acids

Zhiheng Li, Shang Wang, Si-Cong Chen, Xiangwen Zhu, Zhengzhen Lian and Dong Xing

J. Am. Chem. Soc., 2024, 146, 32235
DOI: 10.1021/jacs.4c08957

Grafting Schiff base Cu(II) complex on magnetic graphene oxide as an efficient recyclable catalyst for the synthesis of 4H-pyrano[2,3-b]pyridine-3-carboxylate derivatives

Samaneh Mahmoudi-Gom Yek, Mahmoud Nasrollahzadeh, Davood Azarifar, Akbar Rostami-Vartooni, Masoumeh Ghaemi and Mohammadreza Shokouhimehr

Materials Chemistry and Physics, 2022, 284, 126053
DOI: 10.1016/j.matchemphys.2022.126053

Visible Light-Promoted Transformation of Diazo Compounds via the Formation of Free Carbene as Key Intermediate

Baogui Cai and Jun Xuan

Chinese Journal of Organic Chemistry, 2021, 41, 4565
DOI: 10.6023/cjoc202109040

Cobalt Metallaphotoredox Catalysis Enabled Three‐Component Radical Allylic Sulfonylation via C–H Functionalization†

Maojian Lu, Qian Xiao, Ting‐Ting Miao, Sanliang Li, Qing‐Xiao Tong and Jian‐Ji Zhong

Chin. J. Chem., 2026, 44, 671
DOI: 10.1002/cjoc.70411

Multicomponent Synthesis of 5‐Cyano‐pyrazolo[1,5‐a]pyrimidines Enabled by Aerobic Manganese Catalysis

Heng‐Tong Qu, Zeng‐Hui Wu, Guo‐Chen Zhong, Yan‐Chun Zhang, Cheng‐Tao Feng and Kun Xu

Adv Synth Catal, 2023, 365, 871
DOI: 10.1002/adsc.202201361

Visible-Light-Mediated Three-Component Decarboxylative Coupling Reactions to Synthesize 1,4-Diol Monoethers

Ai Wang, Yu-Yun Yin, Rukhsana, Le-Quan Wang, Jia-Hui Jin and Yong-Miao Shen

J. Org. Chem., 2023, 88, 13871
DOI: 10.1021/acs.joc.3c01483

Photobiocatalytic Reaction: From Single Component to Triple Components

Rui‐Tao Sun, Peng Chen, Sheng‐Zhen Xu, Liang‐Qiu Lu and Wen‐Jing Xiao

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202502489

Pd-Catalyzed 1,4-Difluoromethylative Functionalization of 1,3-Dienes Using Freon-22

Qixin Zhou, Jing Wang, Tiancen Bian, Yan Liang, Weikang Yan, Liejin Zhou and Zuxiao Zhang

Org. Lett., 2024, 26, 9091
DOI: 10.1021/acs.orglett.4c03338

Late‐Stage Deaminative Radical Diversification of Sulfonamides via CuI/Photoredox Synergy: A Direct Strategy for (E)‐β‐Iodovinyl Sulfones

Cheng‐Liang Liu, Jia Liu, Jia‐Ying Dai, Zi‐Rui Kuang, Zhi‐Xing Liu, Qian Yan, Zhi‐Wei Li and Jiang‐Sheng Li

Adv Synth Catal, 2026, 368
DOI: 10.1002/adsc.70068

Arylformylacetonitriles in Multicomponent Reactions Leading to Heterocycles

Yuan Zhong

Eur J Org Chem, 2022, 2022
DOI: 10.1002/ejoc.202201038

Recent Advances in Nickel Catalyzed Asymmetric Acylation Reactions

Yanyan Zhang, Zhuzhu Zhang, Shengqing Zhu and Lingling Chu

Chinese Journal of Organic Chemistry, 2023, 43, 1023
DOI: 10.6023/cjoc202211032

Studying Photochemical Transformations using Electrospray Ionization Mass Spectrometry (ESI‐MS)

Julia V. Burykina and Valentine P. Ananikov

ChemPhotoChem, 2023, 7
DOI: 10.1002/cptc.202200175

Stereoselective vicinal C(sp³)–C bond formation via metallaphotoredox 1,2-difunctionalization of internal alkenes

Yanyan Zhang, Tianyu Long, Yangxing Sun, Ye Yuan, Jing Li, Chuqian Tang, Feng-Ling Qing and Lingling Chu

Nat Commun, 2026, 17
DOI: 10.1038/s41467-026-69838-7

Photocatalytic Reactions Involving Diazo Compounds as Radical Precursors

Yang Xie and Jun Xuan

Chinese Journal of Organic Chemistry, 2022, 42, 4247
DOI: 10.6023/cjoc202207016

Selective 1,4-syn-Addition to Cyclic 1,3-Dienes via Hybrid Palladium Catalysis

Yan Liang, Tiancen Bian, Komal Yadav, Qixin Zhou, Liejin Zhou, Rui Sun and Zuxiao Zhang

ACS Cent. Sci., 2024, 10, 1191
DOI: 10.1021/acscentsci.4c00094

Alkyl-Trifluoromethylation of Glycine Derivatives

Chenxing Zhou, Xudong Wang, Peng Kong, Dongsheng Ji, Pengxin Zhou and Congde Huo

Org. Lett., 2025, 27, 7126
DOI: 10.1021/acs.orglett.5c02028