Crystal engineering: from promise to delivery

Dario Braga

Chem. Commun., 2023, 59, 14052
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Cocrystal formation by anti-solvent slurry

Yi Li, Shun-Yu Li, Xia-Lin Dai, Tong-Bu Lu and Jia-Mei Chen

CrystEngComm, 2023, 25, 5882
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Novel molecular adducts of an anti-cancer drug vandetanib with enhanced solubility

Ravi Kumar Bandaru, Lopamudra Giri, Gamidi Rama Krishna and Rambabu Dandela

CrystEngComm, 2024, 26, 248
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Cocrystals of Favipiravir: Improved Physicochemical Properties and Solution Stability Study

Huimin Li, Lei Wang, Guanying Xie, Changlin Yao, Shuhong Song, Yaqian Qu, Peizhuo Han, Hongshuai Wang, Yanyan Sun, Huachang Wu and Xutang Tao

Crystal Growth & Design, 2023, 23, 8656
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Fluorinated-Triazole-Modified ZnO and Its Application in Marine Antifouling

Yu Yang, Guoqing Wang, Longlin Lei, Yangkai Xiong, Zhiqiang Fang, Lei Huang, Jinbo Liu, Daxiong Hu and Jianhe Liao

Coatings, 2022, 12, 855
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Molecular salts of pipemedic acid and crystal structure, spectral properties, and Hirshfeld surface analysis

J. C. Shwetha, Anamika Sharma and K. Anand Solomon

J IRAN CHEM SOC, 2023, 20, 3161
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Diffusion and Flux Improvement of Drugs through Complexation

M. K. Chaitanya Mannava, Abhijit Garai and Ashwini K. Nangia

Mol. Pharmaceutics, 2023, 20, 2293
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Heterosynthons, Solid Form Design and Enhanced Drug Bioavailability

Ashwini K. Nangia and Gautam R. Desiraju

Angewandte Chemie, 2022, 134
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Synthesis, characterization, and computational studies of a gallic acid-nicotinic acid salt hydrate

Geethanjali N Karthammaiah, N.S. Venkataramanan and K. Anand Solomon

Journal of Molecular Structure, 2025, 1326, 141119
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Torsemide Crystalline Salts with a Significant Spring-Parachute Effect

Xuezhen Deng, Weimin Shi, Kun Qian, Jie Yang, Siyu Yuan and Hong Li

AAPS PharmSciTech, 2024, 25
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Combining crystal engineering and surface engineering to estimate the structure -functions relationship of Tafamidis solid state forms with the aid of machine learning

Prince K. Devadas, Balasankar Thirunavukkarasu and Senthil Kumar Natarajan

International Journal of Pharmaceutics, 2026, 689, 126482
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Co-crystal of nadifloxacin with oxalic acid

Geethanjali N. Karthammaiah, Sreenivasa Rao Amaraneni and Anand K. Solomon

Acta Crystallogr E Cryst Commun, 2023, 79, 319
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Crystal Engineering Strategies for Optimizing Skin Permeation

Ali Samie and Hoda Alavian

Crystal Growth & Design, 2025, 25, 3595
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A Perspective on the Permeability of Cocrystals/Organic Salts of Oral Drugs

Ali Samie and Hoda Alavian

Mol. Pharmaceutics, 2024, 21, 4860
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Importance of Structural Databases, Molecular Pharmacophores, Supramolecular Heterosynthons, and Artificial Intelligence–Machine Learning–Neural Network Tools in Drug Discovery

Ashwini K. Nangia

Crystal Growth & Design, 2024, 24, 6888
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Crystal Engineering of Pharmaceutical Cocrystals in the Discovery and Development of Improved Drugs

Geetha Bolla, Bipul Sarma and Ashwini K. Nangia

Chem. Rev., 2022, 122, 11514
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Heterosynthons, Solid Form Design and Enhanced Drug Bioavailability

Ashwini K. Nangia and Gautam R. Desiraju

Angew Chem Int Ed, 2022, 61
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Bile acids and nanotechnology as emerging platforms for drug delivery

Le Yang Sen, Mikhaela Lorenzo, Mengistie Diress, Susbin Raj Wagle, Abril Mena Balborin, Bozica Kovacevic, Armin Mooranian and Hani Al-Salami

Therapeutic Delivery, 2026, 1
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Cocrystals and Salts of Milrinone with Fluoro Coformers: Improving Drug Dissolution and Diffusion and Calculating Normalized Diffusion for Pharmaceutical Cocrystals

Madhu Rana, Abhijit Garai and Ashwini K. Nangia

Crystal Growth & Design, 2023, 23, 6461
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Exploration of different solid variants of the anticancer medication Panobinostat (PNB) with improved physicochemical attributes

Gowtham Kenguva, Lopamudra Giri, Smruti Rekha Rout, Achyuta Nanda Acharya and Rambabu Dandela

Journal of Molecular Structure, 2023, 1292, 136086
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Interpreting Lattice Water Incorporation in the Enhancement of Solubility and Membrane Permeability of Trimethoprim Molecular Salts

Archita Goswami, Swashat Pran Das, Bikash Kumar Kalita, Tamrat Yimenu Zeleke and Bipul Sarma

Crystal Growth & Design, 2025, 25, 6183
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Construction of a helical single crystal of an enoxacin-sulfosalicylic acid pharmaceutical salt via charge-assisted hydrogen bonds and water-bridge interactions for simultaneous enhancement of solubility and retention of permeability of enoxacin

Yunan Zhang, Xingqi Zhang, Yujiao Li, Lixin Liu, Zhihui Ye, Xiumei Zhang, Xiujuan Ma, Yingli Liu, Hang Geng, Ning Gao and Lingyu Xia

Journal of Molecular Structure, 2026, 1373, 146725
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Two crystalline polymorphs of voriconazole −2,4−dihydroxybenzoic acid cocrystals

Ningbo Gong, Yao Zou, Shiying Yang, Xin Meng, Hongmei Yu, Guorong He, Yang Lu and Guanhua Du

Journal of Molecular Structure, 2025, 1322, 140387
DOI: 10.1016/j.molstruc.2024.140387

Effect of OH and F Substitution in Benzoic Acid Coformers on the Solubility and Permeability of Fluorinated Drug Roflumilast

Shruti Sangwan, Abhijit Garai and Ashwini K. Nangia

Crystal Growth & Design, 2025, 25, 3137
DOI: 10.1021/acs.cgd.5c00191

Enhanced Dissolution and Diffusion of Ribociclib by Salt Formation with Fluorobenzoic Acid Coformers

Shruti Sangwan, Battini Swapna and Ashwini K. Nangia

Crystal Growth & Design, 2024, 24, 2126
DOI: 10.1021/acs.cgd.3c01460