A Challenge for Engineering Biomimetic Microvascular Models: How do we Incorporate the Physiology?

Arinola O. Lampejo, Nien-Wen Hu, Daniela Lucas, Banks M. Lomel, Christian M. Nguyen, Carmen C. Dominguez, Bing Ren, Yong Huang and Walter L. Murfee

Front. Bioeng. Biotechnol., 2022, 10
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Temporal dynamics of angiogenesis: the emerging role of mechanoregulated pathways

Shayan Zarin-Bal, Margot Passier, Katie Bentley and Tommaso Ristori

Biochemical Society Transactions, 2025, 53, 909
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Fluid flow as a driver of embryonic morphogenesis

Margo Daems, Hanna M. Peacock and Elizabeth A. V. Jones

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Local fluid shear stress operates a molecular switch to drive fetal semilunar valve extension

Duc H. Pham, Charles R. Dai, Belle Y. Lin and Jonathan T. Butcher

Developmental Dynamics, 2022, 251, 481
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Instant Intracellular Delivery of miRNA via Photothermal Effect Induced on Plasmonic Pyramid Arrays

Min Sun, Zhenkai Ji, Le He, Chuanzhen Zhao, Liang Ma, Xiuzhen Xu, Erik Jan Cornel, Zhen Fan and Xiaobin Xu

Adv Funct Materials, 2022, 32
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Notch in mechanotransduction – from molecular mechanosensitivity to tissue mechanostasis

Oscar M. J. A. Stassen, Tommaso Ristori and Cecilia M. Sahlgren

Journal of Cell Science, 2020, 133
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Mechano-regulated cell–cell signaling in the context of cardiovascular tissue engineering

Cansu Karakaya, Jordy G. M. van Asten, Tommaso Ristori, Cecilia M. Sahlgren and Sandra Loerakker

Biomech Model Mechanobiol, 2022, 21, 5
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Leveraging femtosecond laser machining for the fabrication of tubular-based Organ-on-Chip systems: modeling cancer metastasis from invasion to intravasation

Mohammad Jouybar, Oscar Stassen, Hamed Moradi, Pan Zuo and Jaap M.J. den Toonder

Materials Today Bio, 2025, 33, 101926
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Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress

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Sci Rep, 2019, 9
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APOE–NOTCH axis governs elastogenesis during human cardiac valve remodeling

Ziyi Liu, Yu Liu, Zhiyun Yu, Cheng Tan, Nicole Pek, Anna O’Donnell, Angeline Wu, Ian Glass, David S. Winlaw, Minzhe Guo, Jason R. Spence, Ya-Wen Chen, Katherine E. Yutzey, Yifei Miao and Mingxia Gu

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High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

Tsutomu Shinohara, Jan-Renier Moonen, Yoon Hong Chun, Yannick C. Lee-Yow, Kenichi Okamura, Jason M. Szafron, Jordan Kaplan, Aiqin Cao, Lingli Wang, Divya Guntur, Shalina Taylor, Sarasa Isobe, Melody Dong, Weiguang Yang, Katherine Guo, Benjamin D. Franco, Cholawat Pacharinsak, Laura J. Pisani, Shinji Saitoh, Yoshihide Mitani, Alison L. Marsden, Jesse M. Engreitz, Jakob Körbelin and Marlene Rabinovitch

ATVB, 2025, 45, 218
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Influence of the Assembly State on the Functionality of a Supramolecular Jagged1-Mimicking Peptide Additive

Matilde Putti, Oscar M. J. A. Stassen, Maaike J. G. Schotman, Cecilia M. Sahlgren and Patricia Y. W. Dankers

ACS Omega, 2019, 4, 8178
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Computational analysis of the role of mechanosensitive Notch signaling in arterial adaptation to hypertension

Jordy G.M. van Asten, Tommaso Ristori, David R. Nolan, Caitríona Lally, Frank P.T. Baaijens, Cecilia M. Sahlgren and Sandra Loerakker

Journal of the Mechanical Behavior of Biomedical Materials, 2022, 133, 105325
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Mechanical regulation of the Notch signaling pathway

Freddy Suarez Rodriguez, Sami Sanlidag and Cecilia Sahlgren

Current Opinion in Cell Biology, 2023, 85, 102244
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Computational Characterization of the Dish-In-A-Dish, A High Yield Culture Platform for Endothelial Shear Stress Studies on the Orbital Shaker

Rob Driessen, Feihu Zhao, Sandra Hofmann, Carlijn Bouten, Cecilia Sahlgren and Oscar Stassen

Micromachines, 2020, 11, 552
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Ex VivoModels to Decipher the Molecular Mechanisms of Genetic Notch Cardiovascular Disorders

Tommaso Ristori, Marika Sjöqvist and Cecilia M. Sahlgren

Tissue Engineering Part C: Methods, 2021, 27, 167
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Notch3 in Development, Health and Disease

Samira Hosseini-Alghaderi and Martin Baron

Biomolecules, 2020, 10, 485
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A multiscale computational model of arterial growth and remodeling including Notch signaling

Jordy G. M. van Asten, Marcos Latorre, Cansu Karakaya, Frank P. T. Baaijens, Cecilia M. Sahlgren, Tommaso Ristori, Jay D. Humphrey and Sandra Loerakker

Biomech Model Mechanobiol, 2023, 22, 1569
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Interplay between Notch signaling and mechanical forces during developmental patterning processes

Shahar Kasirer and David Sprinzak

Current Opinion in Cell Biology, 2024, 91, 102444
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Smad1/5 is acetylated in the dorsal aortae of the mouse embryo before the onset of blood flow, driving early arterial gene expression

Margo Daems, Ljuba C Ponomarev, Rita Simoes-Faria, Max Nobis, Colinda L G J Scheele, Aernout Luttun, Bart Ghesquière, An Zwijsen and Elizabeth A V Jones

Cardiovascular Research, 2024, 120, 2078
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Estimation of shear stress values along endothelial tip cells past the lumen of capillary sprouts

Nien-Wen Hu, Camille D. Rodriguez, Julian A. Rey, Maximillian J. Rozenblum, Connor P. Courtney, Peter Balogh, Malisa Sarntinoranont and Walter L. Murfee

Microvascular Research, 2022, 142, 104360
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Connexin37 Regulates Cell Cycle in the Vasculature

Jennifer S. Fang and Janis M. Burt

J Vasc Res, 2023, 60, 73
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Notch signaling regulates strain-mediated phenotypic switching of vascular smooth muscle cells

Cansu Karakaya, Mark C. van Turnhout, Valery L. Visser, Tommaso Ristori, Carlijn V. C. Bouten, Cecilia M. Sahlgren and Sandra Loerakker

Front. Cell Dev. Biol., 2022, 10
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Notch NICD domains form biomolecular condensates

Tana R. Gazdik, Anamaria Zavala, Henry A. Charlier, Michael A. Detweiler, Jacob J. Crow, Tyler Lawton, David Oke, Saborni Sarker and Allan R. Albig

Journal of Cell Communication and Signaling, 2025, 19
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Understanding the Principles of Pattern Formation Driven by Notch Signaling by Integrating Experiments and Theoretical Models

Federico Bocci, José Nelson Onuchic and Mohit Kumar Jolly

Front. Physiol., 2020, 11
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The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition

Emanuele Azzoni, Vincent Frontera, Giorgio Anselmi, Christina Rode, Chela James, Elitza M. Deltcheva, Atanasiu S. Demian, John Brown, Cristiana Barone, Arianna Patelli, Joe R. Harman, Matthew Nicholls, Simon J. Conway, Edward Morrissey, Sten Eirik W. Jacobsen, Duncan B. Sparrow, Adrian L. Harris, Tariq Enver and Marella F.T.R. de Bruijn

Cell Reports, 2021, 37, 110103
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Mechanical regulation of the early stages of angiogenesis

Sara Barrasa-Ramos, Claire A. Dessalles, Mathieu Hautefeuille and Abdul I. Barakat

J. R. Soc. Interface., 2022, 19
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Endogenous expression of Notch pathway molecules in human trabecular meshwork cells

Kamesh Dhamodaran, Hasna Baidouri, Andrews Nartey, Julia Staverosky, Kate Keller, Ted Acott, Janice A Vranka and Vijay Krishna Raghunathan

Experimental Eye Research, 2022, 216, 108935
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