Synthesis and characterization of CD133 targeted aptamer–drug conjugates for precision therapy of anaplastic thyroid cancer

Ming Hua Ge, Xu Hang Zhu, Yi Ming Shao, Chao Wang, Ping Huang, Yun Wang, Yu Jiang, Yasen Maimaitiyiming, En Chen, Chang Yang and Hua Naranmandura

Biomater. Sci., 2021, 9, 1313
DOI: 10.1039/D0BM01832E

Aptamers: an emerging navigation tool of therapeutic agents for targeted cancer therapy

Chang Yang, Yu Jiang, Sai Heng Hao, Xing Yi Yan, De Fei Hong and Hua Naranmandura

J. Mater. Chem. B, 2022, 10, 20
DOI: 10.1039/D1TB02098F

Nucleic acid therapeutics as differentiation agents for myeloid leukemias

Olivia Kovecses, François E. Mercier and Maureen McKeague

Leukemia, 2024, 38, 1441
DOI: 10.1038/s41375-024-02191-0

Applications of electrochemical biosensor of aptamers-based (APTASENSOR) for the detection of leukemia biomarker

Yuspian Nur, Shabarni Gaffar, Yeni Wahyuni Hartati and Toto Subroto

Sensing and Bio-Sensing Research, 2021, 32, 100416
DOI: 10.1016/j.sbsr.2021.100416

Advances in aptamer-mediated targeted delivery system for cancer treatment

Shiming He, Yue Du, Hongyu Tao and Huaiyu Duan

International Journal of Biological Macromolecules, 2023, 238, 124173
DOI: 10.1016/j.ijbiomac.2023.124173

Cell-specific aptamers as potential drugs in therapeutic applications: A review of current progress

Jieyu Yuhan, Liye Zhu, Longjiao Zhu, Kunlun Huang, Xiaoyun He and Wentao Xu

Journal of Controlled Release, 2022, 346, 405
DOI: 10.1016/j.jconrel.2022.04.039

Aptamers as an approach to targeted cancer therapy

Fatemeh Mahmoudian, Azin Ahmari, Shiva Shabani, Bahman Sadeghi, Shohreh Fahimirad and Fahimeh Fattahi

Cancer Cell Int, 2024, 24
DOI: 10.1186/s12935-024-03295-4

Aptamers: Potential Diagnostic and Therapeutic Agents for Blood Diseases

Maher M. Aljohani, Dana Cialla-May, Jürgen Popp, Raja Chinnappan, Khaled Al-Kattan and Mohammed Zourob

Molecules, 2022, 27, 383
DOI: 10.3390/molecules27020383

Recent progress of SELEX methods for screening nucleic acid aptamers

Chao Zhu, Ziru Feng, Hongwei Qin, Lu Chen, Mengmeng Yan, Linsen Li and Feng Qu

Talanta, 2024, 266, 124998
DOI: 10.1016/j.talanta.2023.124998

Diagnostic application of aptamers against leukemia, multiple myeloma and lymphoma: A review

Saghar Yousefnia and Masoud Negahdary

Journal of Drug Delivery Science and Technology, 2024, 100, 106103
DOI: 10.1016/j.jddst.2024.106103

CD33 targeted EzH1 regulated nanotherapy epigenetically inhibits fusion oncoprotein (AML1-ETO) rearranged acute myeloid leukemia in both in vitro and in vivo Patient Derived Xenograft models

Avinash Chandra Kushwaha, Boddu Mrunalini, Devangi Ghosh, Pankaj Malhotra, Surajit Karmakar and Subhasree Roy Choudhury

Nano Today, 2024, 59, 102542
DOI: 10.1016/j.nantod.2024.102542

Development of Aptamer Screening against Proteins and Its Applications

Li-Ping ZHAO, Ge YANG, Xiao-Min ZHANG and Feng QU

Chinese Journal of Analytical Chemistry, 2020, 48, 560
DOI: 10.1016/S1872-2040(20)60012-3

Recent Development of Aptasensor for Influenza Virus Detection

Soo Min Kim, Jinmyeong Kim, Seungwoo Noh, Hiesang Sohn and Taek Lee

BioChip J, 2020, 14, 327
DOI: 10.1007/s13206-020-4401-2

Aptamer-Drug Conjugates (ApDCs): Transformative approaches in targeted cancer therapy and precision oncology

Amir Mohammad Zahedi, Mohammad Pirouzbakht, Saeed Zanganeh and Ali Afgar

International Journal of Pharmaceutics, 2025, 681, 125902
DOI: 10.1016/j.ijpharm.2025.125902

Cell‐SELEX, an Effective Way to the Discovery of Biomarkers and Unexpected Molecular Events

Tao Bing, Nan Zhang and Dihua Shangguan

Adv. Biosys., 2019, 3
DOI: 10.1002/adbi.201900193

A beginners guide to SELEX and DNA aptamers

Cameron Stephens, Nina M. Goodey and Ueli Gubler

Analytical Biochemistry, 2025, 703, 115890
DOI: 10.1016/j.ab.2025.115890

Advances in aptamer technology and its updated applications in gastric cancer

Sayedeh Azimeh Hosseini, Arghavan Rakhshani Nejad, Hassan Valadbeigi, Mohammad Hossein Haddadi and Monireh Bazdar

Analytical Biochemistry, 2025, 706, 115950
DOI: 10.1016/j.ab.2025.115950

Emerging Biohybrids of Aptamer-Based Nano-Biosensing Technologies for Effective Early Cancer Detection

Thimmaiah Bargavi Ram, Saravanan Krishnan, Jaison Jeevanandam, Michael K. Danquah and Sabu Thomas

Mol Diagn Ther, 2024, 28, 425
DOI: 10.1007/s40291-024-00717-x

Aptamer-drug conjugates: New probes for imaging and targeted therapy

Pingping Liu, Lu Ga, Gerile Aodeng, Yong Wang and Jun Ai

Biosensors and Bioelectronics: X, 2022, 10, 100126
DOI: 10.1016/j.biosx.2022.100126

bioTCIs: Middle-to-Macro Biomolecular Targeted Covalent Inhibitors Possessing Both Semi-Permanent Drug Action and Stringent Target Specificity as Potential Antibody Replacements

Jay Yang, Yudai Tabuchi, Riku Katsuki and Masumi Taki

IJMS, 2023, 24, 3525
DOI: 10.3390/ijms24043525

DISCERN: Dual-Aptamer-Initiated Sensing Circuit via Engineered Nanozyme for Leukemia Stem Cells Phenotyping

Hai Shi, Lu Liu, Ying Shen, Yunlong Xiao, Renwu Mu, Suzhen Zhai, Bin Zhang, Xiaoyan Yang and Chunlin Zhang

ACS Sens., 2026, 11, 1547
DOI: 10.1021/acssensors.5c03906

Aptamer-based approaches in leukemia: a paradigm shift in targeted therapy

Alireza Bayani, Munthar Kadhim Abosaoda, Jasur Rizaev, Mobina Nazari, Zahra Jafari and Hamed Soleimani Samarkhazan

Clin Exp Med, 2025, 25
DOI: 10.1007/s10238-025-01724-w

The Research Advances of Aptamers in Hematologic Malignancies

Yongkang Liao, Shijun Xiong, Zaid Ur Rehman, Xiaoli He, Hongling Peng, Jing Liu and Shuming Sun

Cancers, 2023, 15, 300
DOI: 10.3390/cancers15010300

From Selection to Use: Aptamers as Targeting Reagents in Hematology

Brandon Albert, Fiona Ebanks, Kimia Gharagozloo, Xinying Hai, Raymond Ngu, Sietse Munting and Maureen McKeague

Biomedicines, 2026, 14, 534
DOI: 10.3390/biomedicines14030534

Novel insights into the role of aptamers in the fight against cancer

Yasen Maimaitiyiming, De Fei Hong, Chang Yang and Hua Naranmandura

J Cancer Res Clin Oncol, 2019, 145, 797
DOI: 10.1007/s00432-019-02882-7

The Landscape of Nucleic-Acid-Based Aptamers for Treatment of Hematologic Malignancies: Challenges and Future Directions

Si Wang, Xing Yan, Chang Yang and Hua Naranmandura

Bioengineering, 2022, 9, 635
DOI: 10.3390/bioengineering9110635

Integrating CRISPR-Cas12a with Aptamer as a Logic Gate Biosensing Platform for the Detection of CD33 and CD123

Xinyi Yang, Xiaolong Shi, Chenyu Lv, Wenbin Liu, Fengyue Zhang and Bo Liu

ACS Omega, 2025, 10, 13634
DOI: 10.1021/acsomega.5c00660

Upconversion and downconversion nanoparticles for biophotonics and nanomedicine

Jacky Fong-Chuen Loo, Yi-Hsin Chien, Feng Yin, Siu-Kai Kong, Ho-Pui Ho and Ken-Tye Yong

Coordination Chemistry Reviews, 2019, 400, 213042
DOI: 10.1016/j.ccr.2019.213042