Modified nucleoside triphosphates in bacterial research for in vitro and live-cell applications

Adeline Espinasse, Hannah K. Lembke, Angela A. Cao and Erin E. Carlson

RSC Chem. Biol., 2020, 1, 333
DOI: 10.1039/D0CB00078G

A gene-targeted polymerase-mediated strategy to identifyO6-methylguanine damage

Claudia M. N. Aloisi, Shana J. Sturla and Hailey L. Gahlon

Chem. Commun., 2019, 55, 3895
DOI: 10.1039/C9CC00278B

DNA Adduct-Directed Synthetic Nucleosides

Michael H. Räz, Claudia M. N. Aloisi, Hailey L. Gahlon and Shana J. Sturla

Acc. Chem. Res., 2019, 52, 1391
DOI: 10.1021/acs.accounts.9b00054

Sequence-Specific Quantitation of Mutagenic DNA Damage via Polymerase Amplification with an Artificial Nucleotide

Claudia M. N. Aloisi, Arman Nilforoushan, Nathalie Ziegler and Shana J. Sturla

J. Am. Chem. Soc., 2020, 142, 6962
DOI: 10.1021/jacs.9b11746

The Base Pairing Partner Modulates Alkylguanine Alkyltransferase

Maureen McKeague, Claudia Otto, Michael H. Räz, Todor Angelov and Shana J. Sturla

ACS Chem. Biol., 2018, 13, 2534
DOI: 10.1021/acschembio.8b00446

Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O6-methylguanine in vivo

Alexander Kraus, Maureen McKeague, Nina Seiwert, Georg Nagel, Susanne M. Geisen, Nathalie Ziegler, Ioannis A. Trantakis, Bernd Kaina, Adam D. Thomas, Shana J. Sturla and Jörg Fahrer

Arch Toxicol, 2019, 93, 559
DOI: 10.1007/s00204-018-2355-0

Modified nucleic acids: replication, evolution, and next-generation therapeutics

Karen Duffy, Sebastian Arangundy-Franklin and Philipp Holliger

BMC Biol, 2020, 18
DOI: 10.1186/s12915-020-00803-6

Conformation and Pairing Properties of anO6-Methyl-2′-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA

Andrew H. Kellum, Pradeep S. Pallan, Arman Nilforoushan, Shana J. Sturla, Michael P. Stone and Martin Egli

Chem. Res. Toxicol., 2022, 35, 1903
DOI: 10.1021/acs.chemrestox.2c00165

Snapshots of a modified nucleotide moving through the confines of a DNA polymerase

Heike Maria Kropp, Simon Leonard Dürr, Christine Peter, Kay Diederichs and Andreas Marx

Proc. Natl. Acad. Sci. U.S.A., 2018, 115, 9992
DOI: 10.1073/pnas.1811518115