Microwave irradiation: a green approach for the synthesis of functionalizedN-methyl-1,4-dihydropyridines

M. Musawwer Khan, Saigal Saigal, Sarfaraz Khan, Sumbulunnisan Shareef and Subash C. Sahoo

RSC Adv., 2018, 8, 41892
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A methanol and protic ionic liquid Ugi multicomponent reaction path to cytotoxic α-phenylacetamido amides

Ahmed Al Otaibi, Fiona M. Deane, Cecilia C. Russell, Lacey Hizartzidis, Siobhann N. McCluskey, Jennette A. Sakoff and Adam McCluskey

RSC Adv., 2019, 9, 7652
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Aryl glyoxal: a prime synthetic equivalent for multicomponent reactions in the designing of oxygen heterocycles

Abdur Rehman Sheikh, Anam Arif and Md. Musawwer Khan

RSC Adv., 2023, 13, 11652
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One-pot construction of carbohydrate scaffolds mediated by metal catalysts

Mana Mohan Mukherjee, Sajal Kumar Maity and Rina Ghosh

RSC Adv., 2020, 10, 32450
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Potentially antibreast cancer enamidines via azide–alkyne–amine coupling and their molecular docking studies

Prakash Bansode, Jagannath Jadhav, Rajanikant Kurane, Prafulla Choudhari, Manish Bhatia, Sharanabasappa Khanapure, Rajashri Salunkhe and Gajanan Rashinkar

RSC Adv., 2016, 6, 90597
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Metal–organic frameworks: advanced tools for multicomponent reactions

Mohammad Ali Ghasemzadeh, Boshra Mirhosseini-Eshkevari, Mona Tavakoli and Farzad Zamani

Green Chem., 2020, 22, 7265
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Harnessing alcohols as sustainable reagents for late-stage functionalisation: synthesis of drugs and bio-inspired compounds

Sourajit Bera, Lalit Mohan Kabadwal and Debasis Banerjee

Chem. Soc. Rev., 2024, 53, 4607
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DBU-functionalized MCM-41-coated nanosized hematite (DBU-F-MCM-41-CNSH): a new magnetically separable basic nanocatalyst for the diastereoselective one-pot four-component synthesis of 2-(N-carbamoylacetamide)-substituted 2,3-dihydrothiophenes

Reza Kordnezhadian, Mohsen Shekouhy and Ali Khalafi-Nezhad

New J. Chem., 2019, 43, 18559
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Facile one-pot multicomponent synthesis of peptoid based gelators as novel scaffolds for drug incorporation and pH-sensitive release

Sharol Sebastian, Eqvinshi Yadav, Priya Bhardwaj, Mulaka Maruthi, Deepak Kumar and Manoj K. Gupta

J. Mater. Chem. B, 2023, 11, 9975
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Aryl glyoxal: a prime synthetic equivalent for multicomponent reactions in the designing of oxygen heterocycles

Abdur Rehman Sheikh, Anam Arif and Md. Musawwer Khan

RSC Adv., 2025, 15, 13235
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Cycloamination strategies for renewable N-heterocycles

Hu Li, Haixin Guo, Zhen Fang, Taku Michael Aida and Richard Lee Smith

Green Chem., 2020, 22, 582
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One-step bimodel grafting via a multicomponent reaction toward antifouling and antibacterial TFC RO membranes

Ying Pan, Liujia Ma, Song Lin, Yufeng Zhang, Bowen Cheng and Jianqiang Meng

J. Mater. Chem. A, 2016, 4, 15945
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Recent advances in transition metal-catalyzed (1,n) annulation using (de)-hydrogenative coupling with alcohols

Sourajit Bera, Lalit Mohan Kabadwal and Debasis Banerjee

Chem. Commun., 2021, 57, 9807
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An acid-catalyzed 1,4-addition isocyanide-based multicomponent reaction in neat water

Jie Lei, Yong Li, Jia Xu, Dian-Yong Tang, Jing-Wei Shao, Hong-yu Li, Zhong-Zhu Chen and Zhi-Gang Xu

Green Chem., 2020, 22, 3716
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Recent developments in the synthesis of polysubstituted pyridinesviamulticomponent reactions using nanocatalysts

Fatemeh Majidi Arlan, Ahmad Poursattar Marjani, Ramin Javahershenas and Jabbar Khalafy

New J. Chem., 2021, 45, 12328
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α-Aminoazoles/azines: key reaction partners for multicomponent reactions

Shah Imtiaz, Jahangir Ahmad war, Syqa Banoo and Sarfaraz khan

RSC Adv., 2021, 11, 11083
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NitroketeneN,S-acetals: synergistic building blocks for the synthesis of heterocycles

Saigal Saigal, Sarfaraz Khan, Habibur Rahman, Shafiullah Shafiullah and Md. Musawwer Khan

RSC Adv., 2019, 9, 14477
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Eu2O3 modified CeO2 nanoparticles as a heterogeneous catalyst for an efficient green multicomponent synthesis of novel phenyldiazenyl-acridinedione-carboxylic acid derivatives in aqueous medium

P. Sagar Vijay Kumar, L. Suresh, T. Vinodkumar and G. V. P. Chandramouli

RSC Adv., 2016, 6, 91133
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Multicomponent polysaccharide–protein bioconjugation in the development of antibacterial glycoconjugate vaccine candidates

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Chem. Sci., 2018, 9, 2581
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Efficient one-pot synthesis of new fused pyridines and bis-pyridines catalyzed by triazine diphosphonium hydrogen sulfate ionic liquid supported on functionalized nano-silica

Fahime Rahmani, Iraj Mohammadpoor-Baltork, Ahmad R. Khosropour, Majid Moghadam, Shahram Tangestaninejad and Valiollah Mirkhani

Tetrahedron Letters, 2016, 57, 2294
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An Efficient Five‐Component Reaction for the Synthesis of 4,4′‐((2‐Oxoindoline‐3,3‐diyl)bis(methylene))bis(2‐aryl‐1H‐pyrrolo[3,4‐c]quinoline‐1,3(2H)‐dione) Derivatives

Kaimin Mao, Lei Dai, Yun Liu and Liangce Rong

Journal of Heterocyclic Chem, 2019, 56, 2111
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Trityl Isocyanide as a Mechanistic Probe in Multicomponent Chemistry: Walking the Line between Ugi‐ and Strecker‐type Reactions

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Chemistry A European J, 2016, 22, 7837
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One pot, three component 1,3 dipolar cycloaddition: Regio and diastereoselective synthesis of spiropyrrolidinyl indenoquinoxaline derivatives

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Tetrahedron Letters, 2018, 59, 2688
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Synthesis of various pyrimidines and fused pyrimidines derivatives by telescopic reactions

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Synthesis of Glycomimetics by Diastereoselective Passerini Reaction

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J. Org. Chem., 2018, 83, 13146
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Sugars in Multicomponent Reactions: A Toolbox for Diversity-Oriented Synthesis

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Ca(II)‐Mediated Regioselective One‐pot Sequential Annulation of Acyclic compounds to Polycyclic Fluorenopyrans

Srinivasarao Yaragorla, P. Rajesh, Abhishek Pareek and Ankit Kumar

Adv Synth Catal, 2018, 360, 4422
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Efficient Synthesis of Novel Quinolinone Derivatives via Catalyst-free Multicomponent Reaction

Rui Du, Liangliang Han, Zhongqiang Zhou and Victor Borovkov

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Fe 3 O 4 ‐supported sulfonated graphene oxide as a green and magnetically separable nanocatalyst for synthesis of 2-amino-3-cyano-4 H- chromene derivatives and their in-silico studies

Shaily Sharma, Mahesh Meena, Himanshu Sharma, Dinesh Kumar Yadav, Atul Tiwari and Ved Prakash Verma

Synthetic Communications, 2022, 52, 1926
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Green and Mechanochemical One-Pot Multicomponent Synthesis of Bioactive 2-amino-4H-benzo[b]pyrans via Highly Efficient Amine-Functionalized SiO2@Fe3O4 Nanoparticles

Preeti Singh, Priyanka Yadav, Anupam Mishra and Satish K. Awasthi

ACS Omega, 2020, 5, 4223
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N‐Alkylated C‐Glycosyl Amino Acid Derivatives: Synthesis by a One‐Pot Four‐Component Ugi Reaction

Kristina Vlahoviček‐Kahlina, Zoran Štefanić, Katarina Vazdar and Ivanka Jerić

ChemPlusChem, 2020, 85, 838
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One‐Pot Knoevenagel–Michael–Cyclization Cascade Reaction for the Synthesis of Functionalized Novel 4H‐pyrans by Using ZnCl2 as a Catalyst

M. Musawwer Khan, Saigal and Sarfaraz Khan

Journal of Heterocyclic Chem, 2019, 56, 1020
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Organobase catalyzed synthesis of pyranopyrazoles with X-ray crystallography, docking and ADME studies

Md. Musawwer Khan, Bhoomika Singh, Anam Arif, Saigal and Subash C. Sahoo

Tetrahedron Green Chem, 2024, 4, 100050
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Synthesis and Antioxidant Activity Evaluation of Some Novel Aminocarbonitrile Derivatives Incorporating Carbohydrate Moieties

Soheila Khajeh Dangolani, Farhad Panahi, Zohreh Tavaf, Maryam Nourisefat, Reza Yousefi and Ali Khalafi-Nezhad

ACS Omega, 2018, 3, 10341
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Catalytic synthesis of thiazolidines by the reaction of Nef-isocyanide reaction

Amneh Daghlavi, Elaheh Kowsari, Majid Abdouss, Mohammad Hadi Ghasemi and Elham Asadi

Res Chem Intermed, 2020, 46, 3593
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ZrOCl2·8H2O as an efficient and recyclable catalyst for the one‐pot multicomponent synthesis of novel [1,3]oxazino[5,6‐c]quinolin‐5‐one derivatives

Liangliang Han and Zhongqiang Zhou

Applied Organom Chemis, 2019, 33
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Synthesis of bioactive and fluorescent pyridine-triazole-coumarin peptidomimetics through sequential click-multicomponent reactions

T.V. Soumya, C. Muhammed Ajmal and D. Bahulayan

Bioorganic & Medicinal Chemistry Letters, 2017, 27, 450
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Isocyanide-based Multicomponent Reactions (IMCRs) in Water or Aqueous Biphasic Systems

Chitteti Divyavani, Pannala Padmaja and Pedavenkatagari Narayana Reddy

COS, 2024, 21, 140
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Synthesis of stereo-enriched bis glyco-cyclohexylamines by a one pot dual Petasis reaction

Ayon Sengupta, Rajib Sarkar, Sonali Rudra and Chhanda Mukhopadhyay

Tetrahedron Letters, 2024, 140, 155025
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Multicomponent Reactions in Ligation and Bioconjugation Chemistry

Leslie Reguera, Yanira Méndez, Ana R. Humpierre, Oscar Valdés and Daniel G. Rivera

Acc. Chem. Res., 2018, 51, 1475
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Synthesis, characterization, X-ray crystallographic study and in silico ADME predictions of functionalized nitropyrrole derivatives

Saigal, Mohammad Khizr, Subash C. Sahoo and Md. Musawwer Khan

Journal of Molecular Structure, 2022, 1250, 131655
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Pseudo‐Seven‐Component Double Azido‐Ugi Reaction: an Efficient Synthesis of Bistetrazole Derivatives

Irina V. Kutovaya, Danil P. Zarezin, Olga I. Shmatova and Valentine G. Nenajdenko

Eur J Org Chem, 2019, 2019, 3908
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Reduced graphene oxide-immobilized iron nanoparticles Fe(0)@rGO as heterogeneous catalyst for one-pot synthesis of series of propargylamines

Shelly Kujur and Devendra Deo Pathak

Res Chem Intermed, 2020, 46, 369
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Multicomponent Approach to Homo- and Hetero-Multivalent Glycomimetics Bearing Rare Monosaccharides

Andreja Jakas, Aleksandar Višnjevac and Ivanka Jerić

J. Org. Chem., 2020, 85, 3766
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Organocatalyzed Synthesis and Antifungal Activity of Fully Substituted 1,4‐Dihydropyridines

M. Musawwer Khan, Saigal, Sarfaraz Khan, Sumbulunnisan Shareef and Mohammad Danish

ChemistrySelect, 2018, 3, 6830
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Pyridine-based rigid polymeric structure as a metal-free heterogeneous catalyst for solvent-free synthesis of dihydropyrano[2,3-c]chromene derivatives

Sara Saki, Mohsen Bakhtiarian and Mohammad Mehdi Khodaei

Materials Chemistry and Physics, 2025, 346, 131381
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Facile one-pot synthesis of novel highly functionalized dihydro-1H-pyrrole derivatives catalyzed by molecular iodine

Md. Musawwer Khan, Sarfaraz Khan, Saigal and Abhijeet Singh

Tetrahedron Letters, 2019, 60, 150996
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C-Linked Glycomimetic Libraries Accessed by the Passerini Reaction

Kristina Vlahoviček-Kahlina, Josipa Suć Sajko and Ivanka Jerić

IJMS, 2019, 20, 6236
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Transforming Carbohydrates Through Multicomponent Reactions: Advances and Applications

Priyank Purohit, Ravi Kumar Mittal, Prabhat Kumar Upadhyay and Akanksha Bhatt

ChemistrySelect, 2025, 10
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Heteropolyacid-Containing Ionic Liquid-Catalyzed Multicomponent Synthesis of Bridgehead Nitrogen Heterocycles: Mechanisms and Mitochondrial Staining

Haline G. O. Alvim, Jose R. Correa, José A. F. Assumpção, Wender A. da Silva, Marcelo O. Rodrigues, Julio L. de Macedo, Mariana Fioramonte, Fabio C. Gozzo, Claudia C. Gatto and Brenno A. D. Neto

J. Org. Chem., 2018, 83, 4044
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Multicomponent Reactions Using C,N-Binucleophilic Nature of Aminopyrazoles: Construction of Pyrazole-Fused Heterocycles

Tasneem Parvin

Top Curr Chem (Z), 2023, 381
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Steroid diversification by multicomponent reactions

Leslie Reguera, Cecilia I Attorresi, Javier A Ramírez and Daniel G Rivera

Beilstein J. Org. Chem., 2019, 15, 1236
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Ultrasound assisted synthesis of pyrano[3,2-b]pyran and 7-tosyl-4,7-dihydropyrano[2,3-e]indole scaffolds using barium titanate nanoparticles

Sarfaraz Shaikh, Sarika Rasal and M. M. V. Ramana

Reac Kinet Mech Cat, 2021, 133, 405
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Heterocyclic steroids: Efficient routes for annulation of pentacyclic steroidal pyrimidines

M. Monier, Ahmed El-Mekabaty, Doaa Abdel-Latif, Başak Doğru Mert and Khaled M. Elattar

Steroids, 2020, 154, 108548
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Synthesis library of phthalazines by novel magnetized inorganic-monosaccharide nanohybrid (Ni0.4Zn0.6Fe2O4@SiO2/galactose) under green conditions

Mansoorehsadat Sadathosainy and Kobra Nikoofar

Res Chem Intermed, 2024, 50, 1557
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2-Isocyano glucose used in Ugi four-component reaction: An approach to enhance inhibitory effect against DNA oxidation

Peng-Fei Zhao and Zai-Qun Liu

European Journal of Medicinal Chemistry, 2017, 135, 458
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A green protocol for the synthesis of new 1,4-dihydropyridine derivatives using Fe2O3/ZrO2 as a reusable catalyst

Sandeep V. H. S. Bhaskaruni, Suresh Maddila, Werner E. van Zyl and Sreekantha B. Jonnalagadda

Res Chem Intermed, 2019, 45, 4555
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A Facile and Green Approach for One‐Pot Synthesis of Functionalized Chromeno[3, 4‐b]quinolines and Spiro Chromeno[3, 4‐b]quinolines by Using Molecular Iodine as a Catalyst

M. Musawwer Khan, Saigal, Sarfaraz Khan, Sumbulunnisan Shareef and Sahid Hussain

ChemistrySelect, 2018, 3, 2261
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ChemInform Abstract: Recent Advances in Multicomponent Reactions Involving Carbohydrates

Md. Musawwer Khan, Raveed Yousuf, Sarfaraz Khan and Shafiullah Shafiullah

ChemInform, 2015, 46
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Carbohydrates-based (nano)catalysts in multicomponent reactions: Advances, Limitations and Prospects

Mahdia Hamidinasab, Naeimeh Salehi, Mahsa Alsadat Mostafavi, Mohammad Ali Bodaghifard, Alireza Foroumadi, Tayebeh Akbari and Mehdi Khoobi

Journal of Molecular Structure, 2025, 1341, 142531
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Corrosion inhibition of mild steel in 1M HCl by D-glucose derivatives of dihydropyrido [2,3-d:6,5-d′] dipyrimidine-2, 4, 6, 8(1H,3H, 5H,7H)-tetraone

Chandrabhan Verma, M. A. Quraishi, K. Kluza, M. Makowska-Janusik, Lukman O. Olasunkanmi and Eno E. Ebenso

Sci Rep, 2017, 7
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Amino acids and peptides as reactants in multicomponent reactions: modification of peptides with heterocycle backbones through combinatorial chemistry

Maryam Nourisefat, Farhad Panahi and Ali Khalafi-Nezhad

Mol Divers, 2019, 23, 317
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Efficient and Eco‐Friendly One‐Pot Synthesis of Functionalized Furan‐2‐one, Pyrrol‐2‐one, and Tetrahydropyridine Using Lemon Juice as a Biodegradable Catalyst

M. Musawwer Khan, Sarfaraz Khan, Saigal and Subash C. Sahoo

ChemistrySelect, 2018, 3, 1371
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Cu(BTC)-MOF catalyzed multicomponent reaction to construct 1,4-disubstituted-1,2,3-triazoles

Xiangru Jia, Guangli Xu, Zhengyin Du and Ying Fu

Polyhedron, 2018, 151, 515
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Adsorption Behavior of Glucosamine-Based, Pyrimidine-Fused Heterocycles as Green Corrosion Inhibitors for Mild Steel: Experimental and Theoretical Studies

Chandrabhan Verma, Lukman O. Olasunkanmi, Eno E. Ebenso, M. A. Quraishi and I. B. Obot

J. Phys. Chem. C, 2016, 120, 11598
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Recent progress in metal assisted multicomponent reactions in organic synthesis

Kokila Sakthivel, R. J. Gana, Toshitaka Shoji, Naoko Takenaga, Toshifumi Dohi and Fateh V. Singh

Front. Chem., 2023, 11
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Application of Chiral Isocyanides in Multicomponent Reactions

Vaezeh Fathi Vavsari, Pegah Shakeri and Saeed Balalaie

COC, 2020, 24, 162
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Green Synthesis of Pyrazolo Pyrano Pyrimidine Derivatives Using ZnFe2O4/GA as a New Effective Catalyst in Water Media

Haneye Amini, Shekofeh Neamani and Leila Moradi

ChemistrySelect, 2021, 6, 9608
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Synthesis, Biological Evaluation and Docking Studies of Functionalized Pyrrolo[3,4‐b]pyridine Derivatives

Saigal, Younes S. A. Ghanem, Amad Uddin, Sarfaraz Khan, Mohammad Abid and Md. Musawwer Khan

ChemistrySelect, 2021, 6, 2323
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A new paradigm for designing ring construction strategies for green organic synthesis: implications for the discovery of multicomponent reactions to build molecules containing a single ring

John Andraos

Beilstein J. Org. Chem., 2016, 12, 2420
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On-resin multicomponent protocols for biopolymer assembly and derivatization

Daniel G. Rivera, Manuel G. Ricardo, Aldrin V. Vasco, Ludger A. Wessjohann and Erik V. Van der Eycken

Nat Protoc, 2021, 16, 561
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