Sanguinarine, a promising anticancer therapeutic: photochemical and nucleic acid binding properties

Gopinatha Suresh Kumar and Soumitra Hazra

RSC Adv., 2014, 4, 56518
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Superb-selective chemodosimetric signaling of sulfide in the absence and in the presence of CT-DNA and imaging in living cells by a plant alkaloid berberine analogue

Gopal Chandra Jana, Munira Khatun, Sk Nayim, Somnath Das, Anukul Maji, Maidul Beg, Anirudha Patra, Paromita Bhattacharjee, Kakali Bhadra and Maidul Hossain

New J. Chem., 2019, 43, 2368
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Chelerythrine as a fluorescent light-up ligand for an i-motif DNA structure

Hongbo Chen, Hongxia Sun, Wende Zhang, Qin Zhang, Jun Ma, Qian Li, Xiaomeng Guo, Kanyan Xu and Yalin Tang

New J. Chem., 2021, 45, 28
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Simultaneous fluorescence light-up and selective multicolor nucleobase recognition based on sequence-dependent strong binding of berberine to DNA abasic site

Fei Wu, Yong Shao, Kun Ma, Qinghua Cui, Guiying Liu and Shujuan Xu

Org. Biomol. Chem., 2012, 10, 3300
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Structuring polarity-inverted TBA to G-quadruplex for selective recognition of planarity of natural isoquinoline alkaloids

Yufeng Zhou, Yali Yu, Longlong Gao, Yifan Fei, Ting Ye, Qiusha Li, Xiaoshun Zhou, Ning Gan and Yong Shao

Analyst, 2018, 143, 4907
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New 13-pyridinealkyl berberine analogues intercalate to DNA and induce apoptosis in HepG2 and MCF-7 cells through ROS mediated p53 dependent pathway: biophysical, biochemical and molecular modeling studies

Sabyasachi Chatterjee, Sumana Mallick, Franco Buzzetti, Gaetano Fiorillo, Tanjia Monir Syeda, Paolo Lombardi, Krishna Das Saha and Gopinatha Suresh Kumar

RSC Adv., 2015, 5, 90632
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Novel Inhibitors of an Insect Pest Chitinase: Design and Optimization of 9-O-Aromatic and Heterocyclic Esters of Berberine

Ling Zhu, Lei Chen, Xusheng Shao, Jiagao Cheng, Qing Yang and Xuhong Qian

J. Agric. Food Chem., 2021, 69, 7526
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8,8-Dialkyldihydroberberines with Potent Antiprotozoal Activity

Molla Endeshaw, Xiaohua Zhu, Shanshan He, Trupti Pandharkar, Emily Cason, Kiran V. Mahasenan, Hitesh Agarwal, Chenglong Li, Manoj Munde, W. David Wilson, Mark Bahar, Raymond W. Doskotch, A. Douglas Kinghorn, Marcel Kaiser, Reto Brun, Mark E. Drew and Karl A. Werbovetz

J. Nat. Prod., 2013, 76, 311
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Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells

GAETANO MARVERTI, ALESSIO LIGABUE, PAOLO LOMBARDI, STEFANIA FERRARI, MARIA GIUSEPPINA MONTI, CHIARA FRASSINETI and MARIA PAOLA COSTI

International Journal of Oncology, 2013, 43, 1269
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Interaction of anticancer drug mitoxantrone with DNA hexamer sequence d-(CTCGAG)2 by absorption, fluorescence and circular dichroism spectroscopy

Shilpa Dogra, Pamita Awasthi, Maya Nair and Ritu Barthwal

Journal of Photochemistry and Photobiology B: Biology, 2013, 123, 48
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Biophysical Studies on the Effect of the 13 Position Substitution of the Anticancer Alkaloid Berberine on Its DNA Binding

Debipreeta Bhowmik, Maidul Hossain, Franco Buzzetti, Rosaria D’Auria, Paolo Lombardi and Gopinatha Suresh Kumar

J. Phys. Chem. B, 2012, 116, 2314
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Nucleic acids binding strategies of small molecules: Lessons from alkaloids

Anirban Basu and Gopinatha Suresh Kumar

Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862, 1995
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Evaluation of alkaloids binding to the parallel quadruplex structure [d(TGGGGT)]4 by electrospray ionization mass spectrometry

Niusheng Xu, Hongmei Yang, Meng Cui, Fengrui Song, Zhiqiang Liu and Shuying Liu

J. Mass. Spectrom., 2012, 47, 694
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NMR-based structure of anticancer drug mitoxantrone stacked with terminal base pair of DNA hexamer sequence d-(ATCGAT)2

Shilpa Dogra, Pamita Awasthi, Sweta Tripathi, T.P. Pradeep, Maya S. Nair and Ritu Barthwal

Journal of Biomolecular Structure and Dynamics, 2014, 32, 1164
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New copper complexes inducing bimodal death through apoptosis and autophagy in A549 cancer cells

Noor Shad Gul, Taj-Malook Khan, Ming Chen, Ke-Bin Huang, Cheng Hou, Muhammad Iqbal Choudhary, Hong Liang and Zhen-Feng Chen

Journal of Inorganic Biochemistry, 2020, 213, 111260
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The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1

Carla Bazzicalupi, Marta Ferraroni, Anna Rita Bilia, Francesca Scheggi and Paola Gratteri

Nucleic Acids Research, 2013, 41, 632
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Synthesis, cytotoxicity, and DNA-binding property of berberine derivatives

Cui Liu, Siyuan Liu, Yuechai Wang, Shuxiang Wang, Jinchao Zhang, Shenghui Li, Xinying Qin, Xiaoliu Li, Kerang Wang and Quoqiang Zhou

Med Chem Res, 2014, 23, 1899
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Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

Sneha Singh, Nandini Pathak, Eram Fatima and Arvind Singh Negi

European Journal of Medicinal Chemistry, 2021, 226, 113839
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Fluorescently Sensing of DNA Triplex Assembly Using an Isoquinoline Alkaloid as Selector, Stabilizer, Inducer, and Switch‐On Emitter

Yuehua Hu, Fan Lin, Tao Wu, Ying Wang, Xiao‐Shun Zhou and Yong Shao

Chemistry An Asian Journal, 2016, 11, 2041
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Study on noncovalent complexes of alkaloids with DNA duplex using electrospray ionization mass spectrometry

Lei Ma, Fengrui Song, Zhiqiang Liu and Shuying Liu

Rapid Comm Mass Spectrometry, 2013, 27, 51
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The Phytochemistry of Cherokee Aromatic Medicinal Plants

William N. Setzer

Medicines, 2018, 5, 121
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Advance in identified targets of berberine

Penghai Sun, Ziyuan Wang, Yinchao Ma, Yuan Liu, Yintong Xue, Yan Li, Xiang Gao, Yuedan Wang and Ming Chu

Front. Pharmacol., 2025, 16
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Berberrubine Phosphate: A Selective Fluorescent Probe for Quadruplex DNA

Peter Jonas Wickhorst and Heiko Ihmels

Molecules, 2021, 26, 2566
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Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells

Guojun Jiang, Shuying Dong, Meiling Yu, Xi Han, Chao Zheng, Xiaoguang Zhu and Xuhui Tong

Oncology Letters, 2017, 13, 857
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Evaluation of the size effect of hydrophobic ring substitution on 9-O position of berberine on DNA binding

Munira Khatun, Gopal Chandra Jana, Sk Nayim, Asima Dhal, Anirudha Patra and Maidul Hossain

Journal of Biomolecular Structure and Dynamics, 2023, 41, 14299
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Spectroscopic studies on the binding interaction of novel 13-phenylalkyl analogs of the natural alkaloid berberine to nucleic acid triplexes

Debipreeta Bhowmik, Franco Buzzetti, Gaetano Fiorillo, Paolo Lombardi and Gopinatha Suresh Kumar

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014, 120, 257
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Influence of DNA-binding compounds with cancer preventive activity on the mechanisms of gene expression regulation

K. I. Kirsanov, O. A. Vlasova, T. I. Fetisov, R. G. Zenkov, E. A. Lesovaya, G. A. Belitsky, K. Gurova and M. G. Yakubovskaya

Advances in Molecular Oncology, 2019, 5, 41
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Biophysical Characterization of the Strong Stabilization of the RNA Triplex poly(U)•poly(A)*poly(U) by 9-O-(ω-amino) Alkyl Ether Berberine Analogs

Debipreeta Bhowmik, Suman Das, Maidul Hossain, Lucy Haq, Gopinatha Suresh Kumar and Haiwei Song

PLoS ONE, 2012, 7, e37939
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NMR based structural studies decipher stacking of the alkaloid coralyne to terminal guanines at two different sites in parallel G-quadruplex DNA, [d(TTGGGGT)]4 and [d(TTAGGGT)]4

Kumar Padmapriya and Ritu Barthwal

Biochimica et Biophysica Acta (BBA) - General Subjects, 2017, 1861, 37
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Synthesis of a Naturally Occurring Plant Alkaloid Berberine Analogue and Its Application in Nanomolar Selective Detection of Hydrazine in Free and DNA‐Binding Situation.

Gopal C. Jana, Sk Nayim, Munira Khatun, Somnath Das, Anirudha Patra, Nandan K. Sahoo, Pradeep K. Jha, Samir Mandal, Keya Chaudhuri and Maidul Hossain

ChemistrySelect, 2017, 2, 6519
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A comparative study on the interaction of the putative anticancer alkaloids, sanguinarine and chelerythrine, with single- and double-stranded, and heat-denatured DNAs

Pritha Basu and Gopinatha Suresh Kumar

Journal of Biomolecular Structure and Dynamics, 2015, 33, 2594
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Binding of the anticancer alkaloid sanguinarine with tRNAphe: spectroscopic and calorimetric studies

Maidul Hossain, Ayesha Kabir and Gopinatha Suresh Kumar

Journal of Biomolecular Structure and Dynamics, 2012, 30, 223
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Comparative Analysis of Different DNA‐Binding Drugs for Leishmaniasis Cure: A Pharmacoinformatics Approach

Nutan Chauhan, Ambarish Sharan Vidyarthi and Raju Poddar

Chem Biol Drug Des, 2012, 80, 54
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The benzophenanthridine alkaloid chelerythrine binds to DNA by intercalation: Photophysical aspects and thermodynamic results of iminium versus alkanolamine interaction

Pritha Basu, Debipreeta Bhowmik and Gopinatha Suresh Kumar

Journal of Photochemistry and Photobiology B: Biology, 2013, 129, 57
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Study on the thermodynamics of the binding of iminium and alkanolamine forms of the anticancer agent sanguinarine to human serum albumin

Maidul Hossain, Asma Yasmeen Khan and Gopinatha Suresh Kumar

The Journal of Chemical Thermodynamics, 2012, 47, 90
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Spectroscopic investigation of the interaction between G-quadruplex of KRAS promoter sequence and three isoquinoline alkaloids

Li-Na Wen and Meng-Xia Xie

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017, 171, 287
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Unveiling the Mode of Interaction of Berberine Alkaloid in Different Supramolecular Confined Environments: Interplay of Surface Charge between Nano-Confined Charged Layer and DNA

Niloy Kundu, Arpita Roy, Debasis Banik and Nilmoni Sarkar

J. Phys. Chem. B, 2016, 120, 1106
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Human Telomeric G-Quadruplex Selective Fluoro-Isoquinolines Induce Apoptosis in Cancer Cells

Subhadip Maiti, Puja Saha, Tania Das, Irene Bessi, Harald Schwalbe and Jyotirmayee Dash

Bioconjugate Chem., 2018, 29, 1141
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Synthesis of novel 9-O-N-aryl/aryl–alkyl amino carbonyl methyl substituted berberine analogs and evaluation of DNA binding aspects

Anirban Basu, Parasuraman Jaisankar and Gopinatha Suresh Kumar

Bioorganic & Medicinal Chemistry, 2012, 20, 2498
DOI: 10.1016/j.bmc.2012.03.006

Versatile Triple-Output Molecular Logic Gate for Cysteine and Silver (I) in Foods and the Environment Based on I-Motif DNA Modulation

Yifeng Lan, Yuxin Wei, Yanli Wei, Li Wang and Chuan Dong

J. Agric. Food Chem., 2022, 70, 3608
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Binding of plant alkaloids berberine and palmatine to serum albumins: a thermodynamic investigation

Asma Yasmeen Khan, Maidul Hossain and Gopinatha Suresh Kumar

Mol Biol Rep, 2013, 40, 553
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Interaction of 9-O-N-aryl/arylalkyl amino carbonyl methyl berberine analogs with single stranded ribonucleotides

Anirban Basu, Parasuraman Jaisankar and Gopinatha Suresh Kumar

Journal of Photochemistry and Photobiology B: Biology, 2014, 134, 64
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Berberine-induced nucleolar stress response in a human breast cancer cell line

Minoru Sakaguchi, Daiki Kitaguchi, Shiho Morinami, Yuki Kurashiki, Haruna Hashida, Saki Miyata, Maki Yamaguchi, Miyu Sakai, Natsuko Murata and Satoshi Tanaka

Biochemical and Biophysical Research Communications, 2020, 528, 227
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Isoquinoline based alkaloid chemosensor for detection of alkanes and subsequent fluorescence switching inside surfactant coated bio-mimicking nanocavity

Bibhisan Roy and Partha Hazra

Journal of Molecular Liquids, 2018, 261, 520
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Highly sensitive analysis of tetrodotoxin based on free-label fluorescence aptamer sensing system

Yifeng Lan, Guojie Qin, Yanli Wei, Chuan Dong and Li Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 219, 411
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Cytotoxic and Proapoptotic Activity of Sanguinarine, Berberine, and Extracts of Chelidonium majus L. and Berberis thunbergii DC. toward Hematopoietic Cancer Cell Lines

Anna Och, Daniel Zalewski, Łukasz Komsta, Przemysław Kołodziej, Janusz Kocki and Anna Bogucka-Kocka

Toxins, 2019, 11, 485
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Molecular mechanisms of a promising inhibitor pseudocolumbamine targeting TcCht5 for crop storage pest control

Wenjuan Zhang, Jiaqi Zhang, Zhufeng Geng, Yujie Qu, Hanbing Song, Daowen Li, Chunxue You, Xiaoxue Yu, Chen Liu and Mengxin Li

Journal of Stored Products Research, 2026, 115, 102851
DOI: 10.1016/j.jspr.2025.102851