Issue 39, 2021

Desolvation induced crystal jumping: reversible hydration and dehydration of a spironolactone–saccharin cocrystal with water as the jumping-mate

Abstract

A jumping crystal of the channel-type hydrate of spironolactone–saccharin cocrystals was presented as the first example of a crystal that jumps without changes in both the lattice constant and the molecular conformation, emphasizing the general applicability of our newly proposed design concept that introduces an easy-to-escape component, the jumping-mate, to generate crystal motions.

Graphical abstract: Desolvation induced crystal jumping: reversible hydration and dehydration of a spironolactone–saccharin cocrystal with water as the jumping-mate

Supplementary files

Article information

Article type
Communication
Submitted
23 6 2021
Accepted
22 8 2021
First published
26 8 2021

CrystEngComm, 2021,23, 6838-6842

Desolvation induced crystal jumping: reversible hydration and dehydration of a spironolactone–saccharin cocrystal with water as the jumping-mate

Y. Chen, B. Jing, Z. Chang and J. Gong, CrystEngComm, 2021, 23, 6838 DOI: 10.1039/D1CE00830G

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