Wearable sensors have emerged as a transformative technology, enabling real-time monitoring and advanced functionality in various fields, including healthcare, human–machine interaction, and environmental sensing. This review provides a comprehensive overview of the latest advancements in wearable sensor technologies, focusing on innovations in sensor design, material flexibility, and integration with machine learning. We explore the feasibility of wearable electronics in achieving high-performance, flexible devices and discuss their potential to enhance human–machine interactions through intelligent data processing and decision-making. The combination of wearable electronics and machine learning offers immense potential for applications requiring real-time responsiveness and advanced analytics. By analyzing recent developments of sensors, this review aims to inspire further innovations in this rapidly evolving field, paving the way for the next generation of wearable technologies.