Issue 1, 2024

Eu3+-MOF fluorescence sensor based on a dual-ligand strategy for visualised detection of an anthrax biomarker 2,6-pyridine dicarboxylic acid

Abstract

Bacillus anthracis is an extremely dangerous bacterium that causes high morbidity and mortality. Developing a simple and effective sensor to detect its unique biomarker 2,6-pyridine dicarboxylic acid (DPA) is urgently required to prevent anthrax infection. In this work, a ratiometric fluorescence sensor based on lanthanide–metal–organic frameworks (MOFs) was developed for the sensitive and selective recognition of DPA. Eu-MOF was successfully synthesised by Eu3+, 2,5-thiophenedicarboxylic acid, 2-aminoterephthalic acid, and dimethylformamide (DMF) through a simple solvothermal method. The rationally designed Eu-MOF not only exhibited outstanding sensitivity, strong stability and excellent anti-interference ability for DPA detection but also realised an obvious naked-eye colour change from red to blue with the increasing DPA concentration under UV light. Moreover, a possible detection mechanism involving hydrogen bonding, coordination and photoinduced electron transfer between the Eu-MOF and DPA was proposed. More importantly, the application of Eu-MOF probes in fetal calf serum and tap water also obtained satisfactory results, and the Eu-MOF probes were immobolised onto polyvinyl alcohol membrane, achieving a portable and convenient approach to monitoring DPA.

Graphical abstract: Eu3+-MOF fluorescence sensor based on a dual-ligand strategy for visualised detection of an anthrax biomarker 2,6-pyridine dicarboxylic acid

Supplementary files

Article information

Article type
Research Article
Submitted
14 9 2023
Accepted
08 11 2023
First published
17 11 2023

Inorg. Chem. Front., 2024,11, 269-277

Eu3+-MOF fluorescence sensor based on a dual-ligand strategy for visualised detection of an anthrax biomarker 2,6-pyridine dicarboxylic acid

R. Wang, H. Zhang, J. Sun and Z. Su, Inorg. Chem. Front., 2024, 11, 269 DOI: 10.1039/D3QI01852K

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