Inhibition of Acinetobacter nosocomialis twitching motility by quinolones produced by Pseudomonas aeruginosa

Abstract

Twitching motility in A. nosocomialis is a key virulence factor linked to antibiotic resistance and pathogenicity. This study revealed that the Pseudomonas quinolone signal (PQS) and hydroxy-containing quinolones significantly inhibit motility without affecting bacterial growth, highlighting their potential as targets for controlling bacterial virulence.