Issue 94, 2023

Aggregation-induced emission (AIE)-active metallacycles with near-infrared emission for photodynamic therapy

Abstract

Multifunctional metallacycles with solid-state emission are highly important in cancer therapy. Here, an aggregation-induced emission (AIE)-active metallacycle of DTPABT-MC-R is developed with efficient emission in the NIR region in the solid state (PLQYs = 4.92%). DTPABT-MC-R-based nanoparticles also display excellent photo-stability, and impressive photosensitive characteristics (ROS efficiency = 10.74%), finally leading to applications in cellular imaging and photodynamic therapy (PDT).

Graphical abstract: Aggregation-induced emission (AIE)-active metallacycles with near-infrared emission for photodynamic therapy

Supplementary files

Article information

Article type
Communication
Submitted
25 8 2023
Accepted
01 11 2023
First published
02 11 2023

Chem. Commun., 2023,59, 14021-14024

Aggregation-induced emission (AIE)-active metallacycles with near-infrared emission for photodynamic therapy

Q. Shen, K. Gao, Z. Zhao, A. Gao, Y. Xu, H. Wang, L. Meng, M. Zhang and D. Dang, Chem. Commun., 2023, 59, 14021 DOI: 10.1039/D3CC04166B

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