Issue 68, 2020

Porous materials as carriers of gasotransmitters towards gas biology and therapeutic applications

Abstract

The discovery of NO, CO, and H2S as gasotransmitters and their beneficial role in multiple physiological functions opened an era of research devoted to exogenously delivering them as therapeutic agents. However, the gaseous nature of these molecules demands new forms of administration that enable one to control the location, dosage and timing of their delivery. Porous materials are among the most suitable scaffolds to store, deliver and release gasotransmitters due to their high surface area, tunable composition and reactivity. This review highlights the strategies employed to load and release gasotransmitters from different kinds of porous materials, including zeolites, mesoporous silica, metal–organic frameworks and protein assemblies.

Graphical abstract: Porous materials as carriers of gasotransmitters towards gas biology and therapeutic applications

Article information

Article type
Feature Article
Submitted
26 5 2020
Accepted
14 7 2020
First published
15 7 2020

Chem. Commun., 2020,56, 9750-9766

Porous materials as carriers of gasotransmitters towards gas biology and therapeutic applications

A. Carné-Sánchez, F. J. Carmona, C. Kim and S. Furukawa, Chem. Commun., 2020, 56, 9750 DOI: 10.1039/D0CC03740K

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