Issue 2, 2019

DNA-free directed assembly in single-molecule cut-and-paste

Abstract

Single-molecule cut-and-paste facilitates bottom-up directed assembly of nanoscale biomolecular networks in defined geometries and enables analysis with spatio-temporal resolution. However, arrangement of diverse molecules of interest requires versatile handling systems. The novel DNA-free, genetically encodable scheme described here utilises an orthogonal handling strategy to promote arrangement of enzymes and enzyme networks.

Graphical abstract: DNA-free directed assembly in single-molecule cut-and-paste

Supplementary files

Article information

Article type
Communication
Submitted
25 10 2018
Accepted
01 12 2018
First published
17 12 2018

Nanoscale, 2019,11, 407-411

DNA-free directed assembly in single-molecule cut-and-paste

K. R. Erlich, S. M. Sedlak, M. A. Jobst, L. F. Milles and H. E. Gaub, Nanoscale, 2019, 11, 407 DOI: 10.1039/C8NR08636B

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