Issue 84, 2019

Metal-free sulfonyl radical-initiated cascade cyclization to access sulfonated indolo[1,2-a]quinolines

Abstract

A metal-free cascade reaction was developed for the synthesis of indolo[1,2-a]quinoline derivatives from arylsulfonyl hydrazides and 1-(2-(arylethynyl)phenyl)indoles in the presence of TBAI/TBHP. Impressively, these products exhibit excellent fluorescence properties, which is promising for cell imaging.

Graphical abstract: Metal-free sulfonyl radical-initiated cascade cyclization to access sulfonated indolo[1,2-a]quinolines

Supplementary files

Article information

Article type
Communication
Submitted
05 9 2019
Accepted
19 9 2019
First published
20 9 2019

Chem. Commun., 2019,55, 12615-12618

Metal-free sulfonyl radical-initiated cascade cyclization to access sulfonated indolo[1,2-a]quinolines

K. Sun, X. Chen, Y. Zhang, K. Li, X. Huang, Y. Peng, L. Qu and B. Yu, Chem. Commun., 2019, 55, 12615 DOI: 10.1039/C9CC06924K

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