Issue 27, 2019

A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Abstract

A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

Graphical abstract: A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Supplementary files

Article information

Article type
Communication
Submitted
25 2 2019
Accepted
08 3 2019
First published
08 3 2019
This article is Open Access
Creative Commons BY license

Chem. Commun., 2019,55, 3951-3954

A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Z. Tian, Q. Yan, L. Feng, S. Deng, C. Wang, J. Cui, C. Wang, Z. Zhang, T. D. James and X. Ma, Chem. Commun., 2019, 55, 3951 DOI: 10.1039/C9CC01579E

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