Issue 30, 2017

Recent advances using [Cp*Co(CO)I2] catalysts as a powerful tool for C–H functionalisation

Abstract

Expansion of the synthetic chemists’ toolbox is currently a topic of great interest, with successes providing access to novel compounds and more efficient routes towards new and known pharmaceuticals and agrochemicals. In this context, the development and application of first-row transition metal-catalysed C–H functionalisation protocols is seen as a key opportunity. This perspective provides a brief background of the discovery and application of high-valent cobalt-catalysis in C–H functionalisation, before detailing examples of recent advances in this field using the powerful [Cp*Co(CO)I2] catalysts for both terminal couplings and heterocycle formation. Finally, a discussion on the detection and isolation of elusive reactive intermediates in high-valent cobalt-catalysed C–H functionalisation, shedding light on how these catalyst systems operate, will be provided.

Graphical abstract: Recent advances using [Cp*Co(CO)I2] catalysts as a powerful tool for C–H functionalisation

Article information

Article type
Perspective
Submitted
31 5 2017
Accepted
23 6 2017
First published
26 6 2017

Dalton Trans., 2017,46, 9721-9739

Recent advances using [Cp*Co(CO)I2] catalysts as a powerful tool for C–H functionalisation

P. G. Chirila and C. J. Whiteoak, Dalton Trans., 2017, 46, 9721 DOI: 10.1039/C7DT01980G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements