Issue 6, 2015

Copper-catalysed cross-couplings of arylboronate esters with aryl and heteroaryl iodides and bromides

Abstract

CuI-catalysed coupling of arylboronate esters with aryl and heteroaryl iodides and bromides is described. The transformation affords products in good yields using 5–10 mol% catalyst loadings. The described reaction requires a P,N-based bidentate ligand in combination with CuI for aryl–aryl coupling, but it proceeds without external ligands for aryl–heteroaryl coupling to afford the products. The reaction protocol can also be applied to achieve biarylation of diiodoarenes in reasonable yields.

Graphical abstract: Copper-catalysed cross-couplings of arylboronate esters with aryl and heteroaryl iodides and bromides

Supplementary files

Article information

Article type
Research Article
Submitted
16 12 2014
Accepted
14 2 2015
First published
16 2 2015

Org. Chem. Front., 2015,2, 649-653

Author version available

Copper-catalysed cross-couplings of arylboronate esters with aryl and heteroaryl iodides and bromides

S. K. Gurung, S. Thapa, B. Shrestha and R. Giri, Org. Chem. Front., 2015, 2, 649 DOI: 10.1039/C4QO00331D

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