Issue 1, 2015
From the journal:

Organic Chemistry Frontiers

Chiroptical sensing of oligonucleotides with a cyclic octapyrrole†

Machiko Ie,a   Jun-ichiro Setsune,a   Kazuo Edaa  and  Akihiko Tsuda*a  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe 657-8501, Japan
E-mail: tsuda@harbor.kobe-u.ac.jp

Abstract

A cyclic octapyrrole 8P bearing alkyl and phenyl substituents shows chiroptical responses upon complexation with oligonucleotides in water. It specifically provides a strong CD response with an oligonucleotide that has high thymine content.

Graphical abstract: Chiroptical sensing of oligonucleotides with a cyclic octapyrrole

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Article information

DOI
https://doi.org/10.1039/C4QO00268G
Article type
Research Article
Submitted
20 10 2014
Accepted
27 11 2014
First published
28 11 2014

Org. Chem. Front., 2015,2, 29-33

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Chiroptical sensing of oligonucleotides with a cyclic octapyrrole

M. Ie, J. Setsune, K. Eda and A. Tsuda, Org. Chem. Front., 2015, 2, 29 DOI: 10.1039/C4QO00268G

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