Issue 10, 2014

Enantioselective allylic amination of MBH carbonates catalyzed by novel chiral 4-dialkylaminopyridine catalysts

Abstract

We have investigated the asymmetric allylic amination of Morita–Baylis–Hillman (MBH) carbonates with nitrogen nucleophiles in the presence of newly designed chiral DMAP catalysts. A series of α-methylene β-amino esters were obtained with good yield and selectivities.

Graphical abstract: Enantioselective allylic amination of MBH carbonates catalyzed by novel chiral 4-dialkylaminopyridine catalysts

Supplementary files

Article information

Article type
Research Article
Submitted
26 7 2014
Accepted
09 9 2014
First published
10 9 2014

Org. Chem. Front., 2014,1, 1152-1156

Enantioselective allylic amination of MBH carbonates catalyzed by novel chiral 4-dialkylaminopyridine catalysts

G. Ma and M. P. Sibi, Org. Chem. Front., 2014, 1, 1152 DOI: 10.1039/C4QO00210E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements