Issue 7, 2014

Use of a new water-soluble Zn sensor to determine Zn affinity for the amyloid-β peptide and relevant mutants

Abstract

Evaluation of Zn affinity for the amyloid-β peptide involved in Alzheimer's disease and its modified counterparts is reported. This was made possible by the use of a new water-soluble chelator, the properties of which have also been described. Changes in the peptide sequence that impact Zn affinity are briefly discussed.

Graphical abstract: Use of a new water-soluble Zn sensor to determine Zn affinity for the amyloid-β peptide and relevant mutants

Supplementary files

Article information

Article type
Communication
Submitted
17 1 2014
Accepted
05 3 2014
First published
06 3 2014

Metallomics, 2014,6, 1220-1222

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