Issue 19, 2014
From the journal:

Chemical Communications

A bispyrene derivative as a selective fluorescent probe for RNA†‡

Yifan Liu,a   Eun Jin Jun,a   Gyoungmi Kim,a   Ae-Ree Lee,b   Joon-Hwa Lee*b  and  Juyoung Yoon*a  

* Corresponding authors

a Department of Chemistry and Nano Science, Global Top 5 Research Program, Ewha Womans University, Seoul 120-750, Korea
E-mail: jyoon@ewha.ac.kr
Fax: +82-2-3277-3419
Tel: +82-2-3277-2400

b Department of Chemistry and RINS, Gyeongsang National University, Jinju, Gyeongnam 660-701, Korea
E-mail: joonhwa@gnu.ac.kr

Abstract

A novel bispyrene compound was synthesized to selectively detect RNA through excimer emission “turn-on” in aqueous solution at physiological pH (7.4). The compound was used to successfully image RNA in HeLa cells.

Graphical abstract: A bispyrene derivative as a selective fluorescent probe for RNA

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Article information

DOI
https://doi.org/10.1039/C3CC49430F
Article type
Communication
Submitted
17 12 2013
Accepted
13 1 2014
First published
13 1 2014

Chem. Commun., 2014,50, 2505-2507

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A bispyrene derivative as a selective fluorescent probe for RNA

Y. Liu, E. J. Jun, G. Kim, A. Lee, J. Lee and J. Yoon, Chem. Commun., 2014, 50, 2505 DOI: 10.1039/C3CC49430F

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