Issue 14, 2014
From the journal:

Chemical Communications

A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells†

Meng Li,a   Xumeng Wu,b   Yao Wang,b   Yongsheng Li,b   Weihong Zhu*b  and  Tony D. James*ab  

* Corresponding authors

a Department of Chemistry, University of Bath, Claverton Down, Bath, UK
E-mail: t.d.james@bath.ac.uk
Fax: +44 (0)1225 386231
Tel: +44 (0)1225 383810

b Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science & Technology, Shanghai 200237, P. R. China
E-mail: whzhu@ecust.edu.cn
Fax: +86-21-6425-2758

Abstract

A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF–ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.

Graphical abstract: A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

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Article information

DOI
https://doi.org/10.1039/C3CC48128J
Article type
Communication
Submitted
23 10 2013
Accepted
03 12 2013
First published
04 12 2013
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 1751-1753

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A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

M. Li, X. Wu, Y. Wang, Y. Li, W. Zhu and T. D. James, Chem. Commun., 2014, 50, 1751 DOI: 10.1039/C3CC48128J

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