Issue 40, 2014

A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation

Abstract

The 5-lysyl-hydroxylation has been found among protein post-translational modifications. In this report, we have devised a fluorescence turn-on probe which allows for selectively recognizing 5-hydroxylysine-containing peptides.

Graphical abstract: A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation

Supplementary files

Article information

Article type
Communication
Submitted
30 9 2013
Accepted
22 10 2013
First published
22 10 2013

Chem. Commun., 2014,50, 5298-5300

A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation

C. L. Tung, H. Y. Lam, J. Xu and X. Li, Chem. Commun., 2014, 50, 5298 DOI: 10.1039/C3CC47465H

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