Issue 18, 2013

Nanostructure-induced DNA condensation

Abstract

The control of the DNA condensation process is essential for compaction of DNA in chromatin, as well as for biological applications such as nonviral gene therapy. This review endeavours to reflect the progress of investigations on DNA condensation effects of nanostructure-based condensing agents (such as nanoparticles, nanotubes, cationic polymer and peptide agents) observed by using atomic force microscopy (AFM) and other techniques. The environmental effects on structural characteristics of nanostructure-induced DNA condensates are also discussed.

Graphical abstract: Nanostructure-induced DNA condensation

Article information

Article type
Review Article
Submitted
01 4 2013
Accepted
18 6 2013
First published
20 6 2013

Nanoscale, 2013,5, 8288-8306

Nanostructure-induced DNA condensation

T. Zhou, A. Llizo, C. Wang, G. Xu and Y. Yang, Nanoscale, 2013, 5, 8288 DOI: 10.1039/C3NR01630G

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