Issue 36, 2018

5-Methyl-2-thienylcalcium iodide

Abstract

The reduction of 2-bromo- and 3-bromothiophene with calcium powder gives impure thienylcalcium complexes due to interference of various subsequent metalation and calcium–halogen exchange reactions as well as ether degradation. Therefore, calcium–iodine exchange succeeds via the reaction of trimethylsilylmethylcalcium halide with 3-iodothiophene in tetrahydrofuran at −78 °C in the presence of chloro-trimethylsilane, leading to the quantitative formation of 3-(trimethylsilyl)thiophene. The synthesis and isolation of a thienylcalcium halide, a heavy Grignard reagent with a thienyl group, is possible via the reduction of 2-iodo-5-methylthiophene with activated calcium in THF. Substitution of the thf ligands in 5-methyl-2-thienylcalcium iodide ([5-MeThien-2-Ca(thf)4I], 1) by dissolution in tetrahydropyran (THP) leads to the thp complex of 5-methyl-2-thienylcalcium iodide ([5-MeThien-2-Ca(thp)4I], 2). A low field shift of the calcium-bound carbon atom is characteristic of thienylcalcium complexes.

Graphical abstract: 5-Methyl-2-thienylcalcium iodide

Supplementary files

Article information

Article type
Paper
Submitted
10 4 2018
Accepted
24 4 2018
First published
25 4 2018

Dalton Trans., 2018,47, 12534-12539

5-Methyl-2-thienylcalcium iodide

A. Koch, S. Krieck, H. Görls and M. Westerhausen, Dalton Trans., 2018, 47, 12534 DOI: 10.1039/C8DT01398E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements