Issue 23, 2017

Enzyme-responsive reporter molecules for selective localization and fluorescence imaging of pathogenic biofilms

Abstract

Pathogenic bacteria and their biofilm formation are responsible for a broad spectrum of microbial infections. A novel enzyme-responsive reporter molecule (ERM-1), which can specifically recognize AmpC β-lactamase (Bla) in drug resistant bacteria, has been developed to enable the selective localization of biofilms.

Graphical abstract: Enzyme-responsive reporter molecules for selective localization and fluorescence imaging of pathogenic biofilms

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
21 11 2016
Accepted
22 12 2016
First published
22 12 2016

Chem. Commun., 2017,53, 3330-3333

Enzyme-responsive reporter molecules for selective localization and fluorescence imaging of pathogenic biofilms

J. Aw, F. Widjaja, Y. Ding, J. Mu, Y. Liang and B. Xing, Chem. Commun., 2017, 53, 3330 DOI: 10.1039/C6CC09296A

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