Issue 21, 2012

A chromenoquinoline-based fluorescent off–onthiol probe for bioimaging

Abstract

A new chromenoquinoline-based fluorescent off–onthiol probe 2 is reported. In aqueous buffer solutions at physiological pH, the probe exhibited 223-fold enhancement in fluorescence intensity by a Michael addition of cysteine to the maleimide appended to a chromenoquinoline. Cell permeability and live cell imaging of thiols are also demonstrated.

Graphical abstract: A chromenoquinoline-based fluorescent off–onthiol probe for bioimaging

Supplementary files

Article information

Article type
Communication
Submitted
24 10 2011
Accepted
19 1 2012
First published
19 1 2012

Chem. Commun., 2012,48, 2722-2724

A chromenoquinoline-based fluorescent off–onthiol probe for bioimaging

D. Kand, A. M. Kalle, S. J. Varma and P. Talukdar, Chem. Commun., 2012, 48, 2722 DOI: 10.1039/C2CC16593G

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