Themed collection Journal of Materials Chemistry B Recent Review Articles
A novel surface-enhanced Raman based molecular identification platform for multiplexed and highly accurate clinical diagnosis of viral diseases
Schematic illustration of the E-NoM platform. The workflow for the simultaneous detection of four viral antigens during the infection process.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00796D
Looking back, moving forward: protein corona of lipid nanoparticles
Intelligent delivery of lipid nanoparticles can be achieved through rational design of protein corona as a “troublemaker”.
J. Mater. Chem. B, 2024,12, 5573-5588
https://doi.org/10.1039/D4TB00186A
Trends in bioactivity: inducing and detecting mineralization of regenerative polymeric scaffolds
Advances in bioactive regenerative polymeric scaffolds continue to be made with new materials and methods of characterization.
J. Mater. Chem. B, 2024,12, 2720-2736
https://doi.org/10.1039/D3TB02674D
Enzymatic micro/nanomotors in biomedicine: from single motors to swarms
Micro/nanomotor swarms propelled by diverse mechanisms.
J. Mater. Chem. B, 2024,12, 2711-2719
https://doi.org/10.1039/D3TB02457A
Intestinal retentive systems – recent advances and emerging approaches
Intestinal retentive devices (IRDs) are devices designed to anchor within the lumen of the intestines for long-term residence in the gastrointestinal tract.
J. Mater. Chem. B, 2024,12, 64-78
https://doi.org/10.1039/D3TB01842C
Aggregable gold nanoparticles for cancer photothermal therapy
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB00403E
Exogenous MSCs based tissue regeneration: a review of immuno-protection strategies from biomaterial scaffolds
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB00778F
Application of calcium and phosphorus biomineralization strategy in teeth repair: A systematic review
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB00867G
Magneto-responsive biocomposites in wound healing: from characteristics to functions
Schematic illustrations of the pathways through which magneto-responsive biocomposites promote wound healing.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00743C
Use of photosensitive molecules in the crosslinking of biopolymers: applications and considerations in biomaterials development
The photophysics and photochemical aspects of different photosensitive molecules (photosensitizers and photoinitiators) employed for biopolymers’ crosslinking and their biological impact in developing biomaterials are reviewed.
J. Mater. Chem. B, 2024,12, 6550-6562
https://doi.org/10.1039/D4TB00299G
Progress in ultrasmall ferrite nanoparticles enhanced T1 magnetic resonance angiography
Schematic diagram of design, regulation, and application of UFNPs.
J. Mater. Chem. B, 2024,12, 6521-6531
https://doi.org/10.1039/D4TB00803K
Advances in drug delivery-based therapeutic strategies for renal fibrosis treatment
Renal fibrosis is the result of all chronic kidney diseases and is becoming a major global health hazard.
J. Mater. Chem. B, 2024,12, 6532-6549
https://doi.org/10.1039/D4TB00737A
Recent advances of functional modules for tooth regeneration
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01027B
Nanomaterial Revolutionizes Biosensing: 0D-3D Designs for Ultrasensitive Detection of Microorganisms and Viruses
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01077A
Building in vitro models for mechanistic understanding of liver regeneration in chronic liver diseases
The figure shows how impaired regeneration fuels CLD progression. It depicts how 3D bioprinted models can overcome the limitations of animal models and clinical/histopathological data, and provide mechanistic insights into liver regeneration.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00738G
DNA functionalized programmable hybrid biomaterials for targeted multiplexed applications
With the advent of DNA nanotechnology, DNA-based biomaterials have emerged as a unique class of materials at the center of various biological advances.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00287C
Advancements in electrochemical biosensing of cardiovascular disease biomarkers
Cutting-edge electrochemical biosensing techniques for detecting key cardiovascular disease biomarkers utilizing various technologies are explored.
J. Mater. Chem. B, 2024,12, 6305-6327
https://doi.org/10.1039/D4TB00333K
Advances and perspectives in phototherapy-based combination therapy for cancer treatment
Combining phototherapy with treatments such as chemotherapy and immunotherapy enhances efficacy. This review summarizes strategies, analyzes effects, and discusses future directions in combinational cancer therapies.
J. Mater. Chem. B, 2024,12, 6285-6304
https://doi.org/10.1039/D4TB00483C
Microfluidic-based cardiovascular systems for advanced study of atherosclerosis
This review summarizes the latest advancements in microfluidic-based cardiovascular systems for AS research, encompassing investigations of the underlying pathogenesis and development of diagnostic methods for efficient therapeutic treatments.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00756E
Recent breakthroughs in graphene quantum dot-enhanced sonodynamic and photodynamic therapy
Water-soluble graphene quantum dots (GQDs) have recently exhibited considerable potential for diverse biomedical applications owing to their exceptional optical and chemical properties.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00767K
Recent research progress on tumour-specific responsive hydrogels
Exploring novel advancements in hydrogels tailored for tumor-specific responsiveness, promising breakthroughs in cancer treatment.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00656A
Innovative approaches to wound healing: insights into interactive dressings and future directions
The objective of this review is to provide an up-to-date and all-encompassing account of the recent advancements in the domain of interactive wound dressings.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D3TB02912C
Expanding the boundaries of silk sericin biomaterials in biomedical applications
Unlock the potential of silk sericin (SS) in bioengineering. From its origins to market evolution, explore its diverse applications and future prospects.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00386A
Advances in skin gene therapy: utilizing innovative dressing scaffolds for wound healing, a comprehensive review
Gene-activated matrices are versatile and novel technologies to treat skin wounds. This approach offers a promising avenue for targeted treatment strategies in skin health care.
J. Mater. Chem. B, 2024,12, 6033-6062
https://doi.org/10.1039/D4TB00966E
Recent advances in injectable hydrogel therapies for periodontitis
Schematic illustration of injectable hydrogels in periodontitis treatment.
J. Mater. Chem. B, 2024,12, 6005-6032
https://doi.org/10.1039/D3TB03070A
Surface functionalization of hydroxyapatite nanoparticles for biomedical applications
This review described the highlight of surface engineering of hydroxyapatite nanoparticles and their interactions with ions and molecules, and summarized how the surface functionalization effectively work in biological situations.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00551A
Advances in biomimetic nanomaterial delivery systems: harnessing nature's inspiration for targeted drug delivery
The properties of nanomaterials make them promising and advantageous for use in drug delivery systems, but challenges arise from the immune system's recognition of exogenous nanoparticles, leading to their clearance and reduced targeting efficiency.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00565A
A nanoparticle-assisted signal-enhancement technique for lateral flow immunoassays
This review probes the nanoparticle-assisted amplification strategies for lateral flow immunoassay.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00865K
Advanced nanomaterials for electrochemical sensors: application in wearable tear glucose sensing technology
The recent applications of nanomaterials in tear fluid electrochemical bio-glucose sensors are systematically reviewed. The challenges, strategies, and prospects for those bio-glucose sensor nanomaterials are also emphasized.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00790E
Liquid crystal polymer actuators with complex and multiple actuations
Liquid crystal polymer (LCP) actuators with complex and multiple actuations becomes a hot topic recently. Here, we summarize efforts made for achieving the goals, and furthermore, propose an outlook for LCP actuators with higher intelligence.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01055H
Dissolving microneedles for transdermal drug delivery in cancer immunotherapy
Dissolving microneedles mediated immunotherapeutics delivery for cancer treatment.
J. Mater. Chem. B, 2024,12, 5812-5822
https://doi.org/10.1039/D4TB00659C
Recent advances in stimuli-responsive controlled release systems for neuromodulation
Stimuli-responsive controlled release systems are emerging as powerful tools for precise neuromodulation. This review summarizes the recent progress in different release mechanisms and provides insights into future research direction.
J. Mater. Chem. B, 2024,12, 5769-5786
https://doi.org/10.1039/D4TB00720D
Nanoparticles targeting the adenosine pathway for cancer immunotherapy
Outline of this review on adenosine pathway inhibitors for cancer immunotherapy.
J. Mater. Chem. B, 2024,12, 5787-5811
https://doi.org/10.1039/D4TB00292J
Recent advancements in bio-based dielectric and piezoelectric polymers and their biomedical applications
Bio-based polymers possess distinctive dielectric and piezoelectric properties that make them extremely attractive in a variety of biomedical applications.
J. Mater. Chem. B, 2024,12, 5272-5298
https://doi.org/10.1039/D4TB00231H
Cellular elasticity in cancer: a review of altered biomechanical features
The behavior of cancer cell elasticity is modulated by biological, chemical, and physical changes, which in turn have the potential to alter cellular elasticity, and this may be an encouraging prediction for the future discovery of cancer therapies.
J. Mater. Chem. B, 2024,12, 5299-5324
https://doi.org/10.1039/D4TB00328D
Recent advances in synergistic use of GQD-based hydrogels for bioimaging and drug delivery in cancer treatment
Hydrogel loaded GQDs can be used for targeted bioimaging in specific diseases, including cancer, due to their small size and biocompatibility. GQDs have potential for application in cancer therapy and ability to absorb radiation to make them suitable for photothermal and photodynamic therapies.
J. Mater. Chem. B, 2024,12, 5039-5060
https://doi.org/10.1039/D4TB00024B
Recent progress of UCNPs–MoS2 nanocomposites as a platform for biological applications
Research progress of the UCNPs–MoS2 nanoplatform in biological applications such as biosensing, phototherapy, bioimaging, and targeted drug delivery.
J. Mater. Chem. B, 2024,12, 5024-5038
https://doi.org/10.1039/D3TB02958A
Recent advances in micro/nanomotors for antibacterial applications
Currently, the rapid spread of multidrug-resistant bacteria derived from the indiscriminate use of traditional antibiotics poses a significant threat to public health worldwide.
J. Mater. Chem. B, 2024,12, 5000-5023
https://doi.org/10.1039/D3TB02718J
Antimicrobial therapy based on self-assembling peptides
This paper describes the antimicrobial activity of self-assembled peptides, research progress and assembly strategies.
J. Mater. Chem. B, 2024,12, 5061-5075
https://doi.org/10.1039/D4TB00260A
Nanocellulose-based hydrogels as versatile materials with interesting functional properties for tissue engineering applications
Tissue engineering has emerged as a remarkable field aiming to repair or replace damaged tissues through the use of biomimetic constructs.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00397G
Lipid nanoparticles as the drug carrier for targeted therapy of hepatic disorders
This paper provides a comprehensive review of the structure, composition, and applications of LNPs in the treatment of hepatic disorders and offers insights into prospects and challenges in the future development of LNPs.
J. Mater. Chem. B, 2024,12, 4759-4784
https://doi.org/10.1039/D3TB02766J
Review of NIR-responsive ‘‘Smart’’ carriers for photothermal chemotherapy
This review focuses on the versatile applications of near-infrared (NIR)-responsive smart carriers in biomedical applications, particularly drug delivery and photothermal chemotherapy.
J. Mater. Chem. B, 2024,12, 4785-4808
https://doi.org/10.1039/D3TB03004K
Nanomaterials in modulating tumor-associated macrophages and enhancing immunotherapy
Reprogramming anti-inflammatory macrophages into pro-inflammatory type becomes an efficient antitumor therapeutic approach. With the development of nanotechnology, the strategy of using nanomaterials is an effective option for TAM repolarization.
J. Mater. Chem. B, 2024,12, 4809-4823
https://doi.org/10.1039/D4TB00230J
Biological applications of lipoic acid-based polymers: an old material with new promise
This review highlights the ring-opening polymerization strategies of LA molecules and recent biomedical applications of PLA while discussing the challenges they face and future perspectives.
J. Mater. Chem. B, 2024,12, 4574-4583
https://doi.org/10.1039/D4TB00581C
Application of 3D, 4D, 5D, and 6D bioprinting in cancer research: what does the future look like?
Recent advancements pertaining to the application of 3D, 4D, 5D, and 6D bioprinting in cancer research are discussed, focusing on important challenges and future perspectives.
J. Mater. Chem. B, 2024,12, 4584-4612
https://doi.org/10.1039/D4TB00310A
Amyloid detection in neurodegenerative diseases using MOFs
The adaptability of MOFs allows precise detection and quantification of amyloid proteins. This study delves into how MOFs contribute to detecting amyloid diseases, sorting their uses according to different sensing methods.
J. Mater. Chem. B, 2024,12, 4553-4573
https://doi.org/10.1039/D4TB00373J
Strategies to improve the performance of polyetheretherketone (PEEK) as orthopedic implants: from surface modification to addition of bioactive materials
Various modification strategies have been used to improve the physicochemical and biological properties of PEEK as orthopedic implants.
J. Mater. Chem. B, 2024,12, 4533-4552
https://doi.org/10.1039/D3TB02740F
Advances in magnetoelectric composites for promoting bone regeneration: a review
Magnetoelectric composites are currently used in a number of applications and promote bone regeneration via multiple mechanisms.
J. Mater. Chem. B, 2024,12, 4361-4374
https://doi.org/10.1039/D3TB02617E
Revolutionizing transdermal drug delivery: unveiling the potential of cubosomes and ethosomes
The area of drug delivery systems has witnessed significant advancements in recent years, with a particular focus on improving efficacy, stability, and patient compliance.
J. Mater. Chem. B, 2024,12, 4335-4360
https://doi.org/10.1039/D3TB02927A
Innovative approaches for cancer treatment: graphene quantum dots for photodynamic and photothermal therapies
Recent advancements pertaining to the application of GQD-based nanosystems in photothermal and photodynamic cancer therapies are discussed, highlighting crucial challenges, advantages, and future perspectives.
J. Mater. Chem. B, 2024,12, 4307-4334
https://doi.org/10.1039/D4TB00255E
Self-assembly of peptides in living cells for disease theranostics
In situ self-assembly of peptides in living cells regulated by biocompatible stimuli allows for precise creation of well-defined nanostructures and thus offering a versatile strategy for formulation of biomedical agents at pathological lesions.
J. Mater. Chem. B, 2024,12, 4289-4306
https://doi.org/10.1039/D4TB00365A
Vaccine adjuvants: current status, research and development, licensing, and future opportunities
A comprehensive review of the current landscape and advancements in vaccine adjuvants, providing critical insights into research, development, regulatory licensing, and potential future opportunities for enhancing vaccine efficacy and safety.
J. Mater. Chem. B, 2024,12, 4118-4137
https://doi.org/10.1039/D3TB02861E
Manganese-based nanomaterials promote synergistic photo-immunotherapy: green synthesis, underlying mechanisms, and multiple applications
Manganese-based nanoparticles exhibit the multiple roles of immune adjuvants, photosensitizers and photothermal agents in photo-immunotherapy, enhancing anti-tumor immunity through multiple ways.
J. Mater. Chem. B, 2024,12, 4097-4117
https://doi.org/10.1039/D3TB02844E
Importance of DNA nanotechnology for DNA methyltransferases in biosensing assays
We explore how DNA assembly, including 2D techniques, as well as 3D structures, enhances DNA methyltransferases detection. We highlight the benefits of these DNA nanostructure-based biosensing technologies for clinical use and examine the challenges of standardizing these methods.
J. Mater. Chem. B, 2024,12, 4063-4079
https://doi.org/10.1039/D3TB02947F
A biomimetic camouflaged metal organic framework for enhanced siRNA delivery in the tumor environment
An illustrative depiction highlighting the targeted drug delivery mechanism by bio-functionalized camouflaged MOF nanocarriers that enhances precision by targeting diseased cells and minimizing side effects.
J. Mater. Chem. B, 2024,12, 4080-4096
https://doi.org/10.1039/D3TB02827E
Nanomedicine-induced cell pyroptosis to enhance antitumor immunotherapy
Nanomedicine-induced pyroptosis for efficient antitumor immunotherapy has been increasingly prominent at the current stage. In this review, we provide a comprehensive summary and deep discussion on the very-recent progresses achieved in this field.
J. Mater. Chem. B, 2024,12, 3857-3880
https://doi.org/10.1039/D3TB03017B
Native and engineered extracellular vesicles: novel tools for treating liver disease
This review summarizes the application of native and engineered EVs to treat various liver diseases, which helps understand the current scenario and future research direction.
J. Mater. Chem. B, 2024,12, 3840-3856
https://doi.org/10.1039/D3TB01921G
Synergistic applications of cyclodextrin-based systems and metal–organic frameworks in transdermal drug delivery for skin cancer therapy
This review article explores the innovative field of eco-friendly cyclodextrin-based coordination polymers and metal–organic frameworks (MOFs) for transdermal drug delivery in the case of skin cancer therapy.
J. Mater. Chem. B, 2024,12, 3807-3839
https://doi.org/10.1039/D4TB00312H
Near-infrared-driven upconversion nanoparticles with photocatalysts through water-splitting towards cancer treatment
NIR-driven UCNPs with photocatalysts can absorb UV/vis light via water splitting. Water splitting enables in situ H2, O2, and OH˙ generation under a light source. The nanocomposites can enhance therapeutic approaches for cancer treatment.
J. Mater. Chem. B, 2024,12, 3881-3907
https://doi.org/10.1039/D3TB01066J
Metal–organic framework-based adsorbents for blood purification: progress, challenges, and prospects
This review for the first time summarizes the structure–function relationship between MOFs and toxin adsorption, as well as the biocompatibility and practicality for HD, HP, and ECMO. It is anticipated that this review will expand the interest of researchers for more impact in this area.
J. Mater. Chem. B, 2024,12, 3594-3613
https://doi.org/10.1039/D3TB03047D
Ultrasound-augmented cancer immunotherapy
Illustration of ultrasound-induced enhancement of cancer immunotherapy.
J. Mater. Chem. B, 2024,12, 3636-3658
https://doi.org/10.1039/D3TB02705H
Inorganic nanoparticles for photothermal treatment of cancer
Photothermal therapy (PTT) is a minimally invasive procedure that uses nanoparticles to produce heat from light to kill cancer cells. This review highlights the mechanism of PTT, and the results obtained for the improved therapeutic effect of PTT using the inorganic nanoparticles platform.
J. Mater. Chem. B, 2024,12, 3569-3593
https://doi.org/10.1039/D3TB02797J
Bioinspired and biomimetic strategies for inflammatory bowel disease therapy
IBionic vector constructs have shown therapeutic efficacy in inflammatory bowel disease due to their highly biocompatible “self” nature and specificity in targeting tissues and organs.
J. Mater. Chem. B, 2024,12, 3614-3635
https://doi.org/10.1039/D3TB02995F
Nanocarrier-based gene delivery for immune cell engineering
Nanocarriers hold great potential for engineering immune cells based on their performance (efficiency, safety and specificity). This review focuses on different stages of the transfection process and some important challenges.
J. Mater. Chem. B, 2024,12, 3356-3375
https://doi.org/10.1039/D3TB02279J
Applications and prospects of microneedles in tumor drug delivery
Microneedles that can be inserted and attached to multiple organ sites are considered an innovative platform for delivering anti-tumor drugs, which can be used in various tumor treatment protocols.
J. Mater. Chem. B, 2024,12, 3336-3355
https://doi.org/10.1039/D3TB02646A
Synthesis of pure and doped nano-calcium phosphates using different conventional methods for biomedical applications: a review
Six commonly used synthesis techniques for calcium phosphates are solid-state, mechano-chemical, wet-chemical precipitation, hydrolysis, sol–gel, and hydrothermal methods.
J. Mater. Chem. B, 2024,12, 3376-3391
https://doi.org/10.1039/D3TB02846A
Review on sterilization techniques, and the application potential of phage lyase and lyase immobilization in fighting drug-resistant bacteria
Many human health problems and property losses caused by pathogenic contamination cannot be underestimated.
J. Mater. Chem. B, 2024,12, 3317-3335
https://doi.org/10.1039/D3TB02366D
Electrospun organic/inorganic hybrid nanofibers for accelerating wound healing: a review
This review summarizes fabrication strategies and manifold applications of electrospun organic/inorganic hybrid nanofibers in promoting the wound healing process.
J. Mater. Chem. B, 2024,12, 3171-3190
https://doi.org/10.1039/D4TB00149D
Recent advances in nanotechnology for programmed death ligand 1-targeted cancer theranostics
Advanced nanotechnology developed for PD-L1 detection and PD-L1/PD-1 immune checkpoint-relevant combined cancer therapies is reviewed.
J. Mater. Chem. B, 2024,12, 3191-3208
https://doi.org/10.1039/D3TB02787B
Nanoplatform-based strategies for enhancing the lethality of current antitumor PDT
This review summarizes the recent advances of nanoplatform-based strategies to efficiently amplify the tumoricidal capability of PDT.
J. Mater. Chem. B, 2024,12, 3209-3225
https://doi.org/10.1039/D4TB00008K
About this collection
This collection contains recent Review-type articles published by Journal of Materials Chemistry B, the home for high impact applications, properties and synthesis of exciting new materials for biology and medicine. New articles will be added to this collection as soon as possible after publication.