Small lectin ligands as a basis for applications in glycoscience and glycomedicine

Paul V. Murphy, Ashis Dhara, Liam S. Fitzgerald, Eoin Hever, Saidulu Konda and Kishan Mandal

Chem. Soc. Rev., 2024, 53, 9428
DOI: 10.1039/D4CS00642A

Sugared biomaterial binding lectins: achievements and perspectives

P. Bojarová and V. Křen

Biomater. Sci., 2016, 4, 1142
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Revealing biomedically relevant cell and lectin type-dependent structure–activity profiles for glycoclusters by using tissue sections as an assay platform

Herbert Kaltner, Joachim C. Manning, Gabriel García Caballero, Claudia Di Salvo, Adele Gabba, Laura L. Romero-Hernández, Clemens Knospe, Dan Wu, Harrison C. Daly, Donal F. O'Shea, Hans-Joachim Gabius and Paul V. Murphy

RSC Adv., 2018, 8, 28716
DOI: 10.1039/C8RA05382K

Fluorescent glycoconjugates and their applications

Baptiste Thomas, Kai-Cheng Yan, Xi-Le Hu, Marion Donnier-Maréchal, Guo-Rong Chen, Xiao-Peng He and Sébastien Vidal

Chem. Soc. Rev., 2020, 49, 593
DOI: 10.1039/C8CS00118A

Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin

Donella M. Beckwith, Forrest G. FitzGerald, Maria C. Rodriguez Benavente, Elizabeth R. Mercer, Anna-Kristin Ludwig, Malwina Michalak, Herbert Kaltner, Jürgen Kopitz, Hans-Joachim Gabius and Maré Cudic

Biochemistry, 2021, 60, 547
DOI: 10.1021/acs.biochem.0c00942

Enantioselective Degrader for Elimination of Extracellular Aggregation-Prone Proteins hIAPP Associated with Type 2 Diabetes

Zhenqi Liu, Dongqin Yu, Hualong Song, Miles L. Postings, Peter Scott, Zhao Wang, Jinsong Ren and Xiaogang Qu

ACS Nano, 2023, 17, 8141
DOI: 10.1021/acsnano.2c11476

Coiled coil type neoglycoproteins presenting three lactose residues

Sinclair M. Sweeney, Gemma A. Bullen, Richard B. Gillis, Gary G. Adams, Arthur J. Rowe, Stephen E. Harding, James H.R. Tucker, Anna F.A. Peacock and Paul V. Murphy

Tetrahedron Letters, 2016, 57, 1414
DOI: 10.1016/j.tetlet.2016.02.005

MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response

Adele Gabba, Riem Attariya, Sandra Behren, Christian Pett, Joost C. van der Horst, Hajime Yurugi, Jin Yu, Moritz Urschbach, Juan Sabin, Gabriel Birrane, Edgar Schmitt, Sandra J. van Vliet, Pol Besenius, Ulrika Westerlind and Paul V. Murphy

J. Am. Chem. Soc., 2023, 145, 13027
DOI: 10.1021/jacs.2c12843

How altering the modular architecture affects aspects of lectin activity: case study on human galectin-1

Tanja J Kutzner, Adele Gabba, Forrest G FitzGerald, Nadezhda V Shilova, Gabriel García Caballero, Anna-Kristin Ludwig, Joachim C Manning, Clemens Knospe, Herbert Kaltner, Fred Sinowatz, Paul V Murphy, Mare Cudic, Nicolai V Bovin and Hans-Joachim Gabius

Glycobiology, 2019, 29, 593
DOI: 10.1093/glycob/cwz034

Mechanistic Insight into Nanomolar Binding of Multivalent Neoglycopeptides to Wheat Germ Agglutinin

Philipp Rohse and Valentin Wittmann

Chemistry A European J, 2016, 22, 9724
DOI: 10.1002/chem.201600657

Design and Synthesis of Dual Galectin‐3 and EGFR Inhibitors Against Liver Fibrosis

Shuanglin Liu, Fei He, Can Jin, Qing Li, Guilong Zhao and Kan Ding

Chemistry An Asian Journal, 2025, 20
DOI: 10.1002/asia.202401078

Structural Insights into the Binding of Sugar Receptors (Lectins) to a Synthetic Tricyclic Tn Mimetic and Its Glycopeptide Version

Ana Ardá, Rosa Bosco, Javier Sastre, F. Javier Cañada, Sabine André, Hans‐Joachim Gabius, Barbara Richichi, Jesus Jiménez‐Barbero and Cristina Nativi

Eur J Org Chem, 2015, 2015, 6823
DOI: 10.1002/ejoc.201500874

Cu(I)-Catalyzed Click Chemistry in Glycoscience and Their Diverse Applications

Anand K. Agrahari, Priyanka Bose, Manoj K. Jaiswal, Sanchayita Rajkhowa, Anoop S. Singh, Srinivas Hotha, Nidhi Mishra and Vinod K. Tiwari

Chem. Rev., 2021, 121, 7638
DOI: 10.1021/acs.chemrev.0c00920

Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context

Sabine André, Herbert Kaltner, Klaus Kayser, Paul V. Murphy and Hans-Joachim Gabius

Histochem Cell Biol, 2016, 145, 185
DOI: 10.1007/s00418-015-1383-6

Synthesis of 1,4-imino-L-lyxitols modified at C-5 and their evaluation as inhibitors of GH38 α-mannosidases

Maroš Bella, Sergej Šesták, Ján Moncoľ, Miroslav Koóš and Monika Poláková

Beilstein J. Org. Chem., 2018, 14, 2156
DOI: 10.3762/bjoc.14.189

GalNAc-Tyrosine Is a Ligand of Plant Lectins, Antibodies, and Human and Murine Macrophage Galactose-Type Lectins

Ruslan Gibadullin, David Wayne Farnsworth, Joseph J. Barchi and Jeffrey C. Gildersleeve

ACS Chem. Biol., 2017, 12, 2172
DOI: 10.1021/acschembio.7b00471

Promotion of a Reaction by Cooling: Stereoselective 1,2‐cis‐α‐Thioglycoconjugation by Thiol‐Ene Coupling at −80 °C

Dániel Eszenyi, Viktor Kelemen, Fanny Balogh, Miklós Bege, Magdolna Csávás, Pál Herczegh and Anikó Borbás

Chemistry A European J, 2018, 24, 4532
DOI: 10.1002/chem.201800668

Lewis Acid Induced Anomerization of Se-Glycosides. Application to Synthesis of α-Se-GalCer

Anthony W. McDonagh, Mary F. Mahon and Paul V. Murphy

Org. Lett., 2016, 18, 552
DOI: 10.1021/acs.orglett.5b03591

Glycoclusters as lectin inhibitors: comparative analysis on two plant agglutinins with different folding as a step towards rules for selectivity

Sabine André, Shane O'Sullivan, Hans-Joachim Gabius and Paul V. Murphy

Tetrahedron, 2015, 71, 6867
DOI: 10.1016/j.tet.2015.07.020