Protein-encapsulated fluorogenic probes for the selective detection of endogenous O-GlcNAcase (OGA)

Yuan-Hao Wu, Chen Guo, Zi-Ru Ye, Xi-Le Hu, Tony D. James, Jia Li and Xiao-Peng He

Chem. Sci., 2026
DOI: 10.1039/D5SC06843F

Exploring conformational preferences of proteins: ionic liquid effects on the energy landscape of avidin

Talia A. Shmool, Laura K. Martin, Coby J. Clarke, Liem Bui-Le, Karen M. Polizzi and Jason P. Hallett

Chem. Sci., 2021, 12, 196
DOI: 10.1039/D0SC04991C

Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes

Hai-Hao Han, Adam C. Sedgwick, Ying Shang, Na Li, Tingting Liu, Bo-Han Li, Kunqian Yu, Yi Zang, James T. Brewster, Maria L. Odyniec, Maria Weber, Steven D. Bull, Jia Li, Jonathan L. Sessler, Tony D. James, Xiao-Peng He and He Tian

Chem. Sci., 2020, 11, 1107
DOI: 10.1039/C9SC03961A

Preorganized cyclic modules facilitate the self-assembly of protein nanostructures

Jaka Snoj, Fabio Lapenta and Roman Jerala

Chem. Sci., 2024, 15, 3673
DOI: 10.1039/D3SC06658D

Perspectives on solution-based small angle X-ray scattering for protein and biological macromolecule structural biology

Ahmed S. A. Mohammed, Dmytro Soloviov and Cy M. Jeffries

Phys. Chem. Chem. Phys., 2024, 26, 25268
DOI: 10.1039/D4CP02001D

Structural analysis of the LDL receptor–interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site

Luca Martinelli, Athanassios Adamopoulos, Patrik Johansson, Paul T. Wan, Jenny Gunnarsson, Hongwei Guo, Helen Boyd, Noam Zelcer and Titia K. Sixma

Journal of Biological Chemistry, 2020, 295, 13570
DOI: 10.1074/jbc.RA120.014349

Possibility of two-dimensional ordering of cryptochrome 4a from European robin

Shigeki Arai, Ryoma Kobayashi, Motoyasu Adachi, Koji Kimura and Hirokazu Masai

Biochemical and Biophysical Research Communications, 2024, 737, 150513
DOI: 10.1016/j.bbrc.2024.150513

Projection to extract the perpendicular component (PEPC) method for extracting kinetics from time-resolved data

H. Ki, J. Gu, Y. Cha, K. W. Lee and H. Ihee

Structural Dynamics, 2023, 10
DOI: 10.1063/4.0000189

Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme

Ashish

Journal of Biomolecular Structure and Dynamics, 2022, 40, 12975
DOI: 10.1080/07391102.2021.1977704

Visualizing gaussian-chain like structural models of human α-synuclein in monomeric pre-fibrillar state: Solution SAXS data and modeling analysis

Madhumita Dey, Arpit Gupta, Maulik D. Badmalia, Ashish and Deepak Sharma

International Journal of Biological Macromolecules, 2025, 288, 138614
DOI: 10.1016/j.ijbiomac.2024.138614

Three-dimensional structure of the 3′X-tail of hepatitis C virus RNA in monomeric and dimeric states

Ángel Cantero-Camacho, Lixin Fan, Yun-Xing Wang and José Gallego

RNA, 2017, 23, 1465
DOI: 10.1261/rna.060632.117

Alginate-ionic liquid injectable hydrogels supporting protein crystallization

Qi Han, Junhua Li, Zachary P.J. Candiloro, Xudong Cai, Yuyu Su, Haiyan Li, Nhiem Tran, Jiali Zhai, Andrew V. Martin, Calum J. Drummond and Tamar L. Greaves

International Journal of Biological Macromolecules, 2025, 307, 142166
DOI: 10.1016/j.ijbiomac.2025.142166

Analysis of biostructural changes, dynamics, and interactions – Small-angle X-ray scattering to the rescue

Bente Vestergaard

Archives of Biochemistry and Biophysics, 2016, 602, 69
DOI: 10.1016/j.abb.2016.02.029

A Giant Extracellular Matrix Binding Protein of Staphylococcus epidermidis Binds Surface-Immobilized Fibronectin via a Novel Mechanism

Henning Büttner, Markus Perbandt, Thomas Kohler, Alexey Kikhney, Manuel Wolters, Martin Christner, Marisol Heise, Jérôme Wilde, Samira Weißelberg, Anna Both, Christian Betzel, Sven Hammerschmidt, Dmitri Svergun, Martin Aepfelbacher, Holger Rohde and Tarek Msadek

mBio, 2020, 11
DOI: 10.1128/mBio.01612-20

SANS investigation of fungal loosenins reveals substrate-dependent impacts of protein action on the inter-microfibril arrangement of cellulosic substrates

Deepika Dahiya, Zsuzsanna Péter-Szabó, Manjula Senanayake, Sai Venkatesh Pingali, Wellington C. Leite, James Byrnes, Garry W. Buchko, Pramod Sivan, Francisco Vilaplana, Emma R. Master and Hugh O’Neill

Biotechnol. Biofuels Bioprod., 2025, 18
DOI: 10.1186/s13068-025-02618-5

Form factor determination of biological molecules with X-ray free electron laser small-angle scattering (XFEL-SAS)

Clement E. Blanchet, Adam Round, Haydyn D. T. Mertens, Kartik Ayyer, Melissa Graewert, Salah Awel, Daniel Franke, Katerina Dörner, Saša Bajt, Richard Bean, Tânia F. Custódio, Raphael de Wijn, E. Juncheng, Alessandra Henkel, Andrey Gruzinov, Cy M. Jeffries, Yoonhee Kim, Henry Kirkwood, Marco Kloos, Juraj Knoška, Jayanath Koliyadu, Romain Letrun, Christian Löw, Jana Makroczyova, Abhishek Mall, Rob Meijers, Gisel Esperanza Pena Murillo, Dominik Oberthür, Ekaterina Round, Carolin Seuring, Marcin Sikorski, Patrik Vagovic, Joana Valerio, Tamme Wollweber, Yulong Zhuang, Joachim Schulz, Heinrich Haas, Henry N. Chapman, Adrian P. Mancuso and Dmitri Svergun

Commun Biol, 2023, 6
DOI: 10.1038/s42003-023-05416-7

Coupling of Spectrin Repeat Modules for the Assembly of Nanorods and Presentation of Protein Domains

Klemen Mezgec, Jaka Snoj, Liza Ulčakar, Ajasja Ljubetič, Magda Tušek Žnidarič, Miha Škarabot and Roman Jerala

ACS Nano, 2024, 18, 28748
DOI: 10.1021/acsnano.4c07701

Structural insights of an LCP protein–LytR–from Streptococcus dysgalactiae subs. dysgalactiae through biophysical and in silico methods

João Paquete-Ferreira, Filipe Freire, Henrique S. Fernandes, Jayaraman Muthukumaran, João Ramos, Joana Bryton, Alejandro Panjkovich, Dmitri Svergun, Marino F. A. Santos, Márcia A. S. Correia, Alexandra R. Fernandes, Maria João Romão, Sérgio F. Sousa and Teresa Santos-Silva

Front. Chem., 2024, 12
DOI: 10.3389/fchem.2024.1379914

Structure of the mouse acidic amino acid decarboxylase GADL1

Arne Raasakka, Elaheh Mahootchi, Ingeborg Winge, Weisha Luan, Petri Kursula and Jan Haavik

Acta Crystallogr F Struct Biol Commun, 2018, 74, 65
DOI: 10.1107/S2053230X17017848

Conformational multiplicity of bacterial ferric binding protein revealed by small angle x-ray scattering and molecular dynamics calculations

Goksin Liu, Erhan Ekmen, Farzaneh Jalalypour, Haydyn D. T. Mertens, Cy M. Jeffries, Dmitri Svergun, Ali Rana Atilgan, Canan Atilgan and Zehra Sayers

The Journal of Chemical Physics, 2023, 158
DOI: 10.1063/5.0136558

Structural characterization of the human DjC20/HscB cochaperone in solution

Amanda Lais de Souza Coto, Arthur Alexandre Pereira, Sabrina Dorta Oliveira, Milene Nobrega de Oliveira Moritz, Arthur Moraes Franco da Rocha, Paulo Roberto Dores-Silva, Noeli Soares Melo da Silva, Ana Rita de Araújo Nogueira, Lisandra Marques Gava, Thiago Vagas Seraphim and Júlio César Borges

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2024, 1872, 140970
DOI: 10.1016/j.bbapap.2023.140970

Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation

Komal Soni, Georg Kempf, Karen Manalastas-Cantos, Astrid Hendricks, Dirk Flemming, Julien Guizetti, Bernd Simon, Friedrich Frischknecht, Dmitri I. Svergun, Klemens Wild and Irmgard Sinning

Commun Biol, 2021, 4
DOI: 10.1038/s42003-021-02132-y

Small angle X-ray scattering investigation of ionic liquid effect on the aggregation behavior of globular proteins

Qi Han, Mohamad El Mohamad, Stuart Brown, Jiali Zhai, Carlos J. Rosado, Yi Shen, Ewan W. Blanch, Calum J. Drummond and Tamar L. Greaves

Journal of Colloid and Interface Science, 2023, 648, 376
DOI: 10.1016/j.jcis.2023.05.130

Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors

Victor Hugo Pérez Carrillo, Jacob J. Whittaker, Christoph Wiedemann, Jean-Martin Harder, Theresa Lohr, Anil K. Jamithireddy, Marina Dajka, Benedikt Goretzki, Benesh Joseph, Albert Guskov, Nicholas J. Harmer, Ulrike Holzgrabe and Ute A. Hellmich

J. Med. Chem., 2025, 68, 5926
DOI: 10.1021/acs.jmedchem.5c00134

Normal Mode Analysis as a Routine Part of a Structural Investigation

Jacob A. Bauer, Jelena Pavlović and Vladena Bauerová-Hlinková

Molecules, 2019, 24, 3293
DOI: 10.3390/molecules24183293

X‐ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double‐strand break repair impacting cell and cancer biology

Michal Hammel and John A. Tainer

Protein Science, 2021, 30, 1735
DOI: 10.1002/pro.4133

Evolutionary shaping of low-dimensional path facilitates robust and plastic switching between phenotypes

Ayaka Sakata and Kunihiko Kaneko

Phys. Rev. Research, 2023, 5
DOI: 10.1103/PhysRevResearch.5.043296

Silica Nanoparticle–Protein Aggregation and Protein Corona Formation Investigated with Scattering Techniques

Qi Han, Zachary P. J. Candiloro, Xudong Cai, Mohamad El Mohamad, Brendan P. Dyett, Carlos J. Rosado, Jiali Zhai, Gary Bryant, Calum J. Drummond and Tamar L. Greaves

ACS Appl. Mater. Interfaces, 2025, 17, 8574
DOI: 10.1021/acsami.4c19591

Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain

Yovana Cabrera, Leire Dublang, José Angel Fernández-Higuero, David Albesa-Jové, Maria Lucas, Ana Rosa Viguera, Marcelo E. Guerin, Jose M.G. Vilar, Arturo Muga and Fernando Moro

Journal of Molecular Biology, 2019, 431, 444
DOI: 10.1016/j.jmb.2018.11.026

Recent advances in structural characterization of biomacromolecules in foods via small-angle X-ray scattering

Yang Sun, Xiujuan Li, Ruixin Chen, Fei Liu and Song Wei

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.1039762

Albumin in patients with liver disease shows an altered conformation

Margret Paar, Vera H. Fengler, Daniel J. Rosenberg, Angelika Krebs, Rudolf E. Stauber, Karl Oettl and Michal Hammel

Commun Biol, 2021, 4
DOI: 10.1038/s42003-021-02269-w

Unconventional structure and mechanisms for membrane interaction and translocation of the NF-κB-targeting toxin AIP56

Johnny Lisboa, Cassilda Pereira, Rute D. Pinto, Inês S. Rodrigues, Liliana M. G. Pereira, Bruno Pinheiro, Pedro Oliveira, Pedro José Barbosa Pereira, Jorge E. Azevedo, Dominique Durand, Roland Benz, Ana do Vale and Nuno M. S. dos Santos

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-43054-z

The structure of the MutL-CTD:processivity-clamp complex provides insight regarding strand discrimination in non-methyl-directed DNA mismatch repair

Shivlee Nirwal, Ritika Jha, Naveen Narayanan, Minakshi Sharma, Dhananjaya S Kulkarni, Dalchand Sharma, Amith S Babu, Dhiraj K Suthar, Desirazu N Rao and Deepak T Nair

Nucleic Acids Research, 2025, 53
DOI: 10.1093/nar/gkaf094

Solution structure and flexibility of the condensin HEAT-repeat subunit Ycg1

Karen Manalastas-Cantos, Marc Kschonsak, Christian H. Haering and Dmitri I. Svergun

Journal of Biological Chemistry, 2019, 294, 13822
DOI: 10.1074/jbc.RA119.008661

Extended Sampling of Macromolecular Conformations from Uniformly Distributed Points on Multidimensional Normal Mode Hyperspheres

Antoniel A. S. Gomes, Mauricio G. S. Costa, Maxime Louet, Nicolas Floquet, Paulo M. Bisch and David Perahia

J. Chem. Theory Comput., 2024, 20, 10770
DOI: 10.1021/acs.jctc.4c01054

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

Daniel P. Duarte, Allan J. Lamontanara, Giuseppina La Sala, Sukyo Jeong, Yoo-Kyoung Sohn, Alejandro Panjkovich, Sandrine Georgeon, Tim Kükenshöner, Maria J. Marcaida, Florence Pojer, Marco De Vivo, Dmitri Svergun, Hak-Sung Kim, Matteo Dal Peraro and Oliver Hantschel

Nat Commun, 2020, 11
DOI: 10.1038/s41467-020-16128-5

Conformational Changes and Flexibility of DNA Devices Observed by Small-Angle X-ray Scattering

Linda K. Bruetzel, Thomas Gerling, Steffen M. Sedlak, Philipp U. Walker, Wenjun Zheng, Hendrik Dietz and Jan Lipfert

Nano Lett., 2016, 16, 4871
DOI: 10.1021/acs.nanolett.6b01338

Search for non-lactam inhibitors of mtb β-lactamase led to its open shape in apo state: new concept for antibiotic design

Amin Sagar, Nazia Haleem, Yaawar Mir Bashir and Ashish

Sci Rep, 2017, 7
DOI: 10.1038/s41598-017-06023-3

Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM

Michal Hammel, Daniel J. Rosenberg, Jan Bierma, Gregory L. Hura, Roopa Thapar, Susan P. Lees-Miller and John A. Tainer

Progress in Biophysics and Molecular Biology, 2021, 163, 74
DOI: 10.1016/j.pbiomolbio.2020.09.003

Toscana virusnucleoprotein oligomer organization observed in solution

Amal Baklouti, Adeline Goulet, Julie Lichière, Bruno Canard, Rémi N. Charrel, François Ferron, Bruno Coutard and Nicolas Papageorgiou

Acta Crystallogr D Struct Biol, 2017, 73, 650
DOI: 10.1107/S2059798317008774

Structural Characterization of Arabidopsis thaliana NAP1-Related Protein 2 (AtNRP2) and Comparison with Its Homolog AtNRP1

Ashish Kumar, Ajit Kumar Singh, Ruchir Chandrakant Bobde and Dileep Vasudevan

Molecules, 2019, 24, 2258
DOI: 10.3390/molecules24122258

Heme-Edge Residues Modulate Signal Transduction within a Bifunctional Homo-Dimeric Sensor Protein

Dayna C. Patterson, Yilin Liu, Sayan Das, Neela H. Yennawar, Jean-Paul Armache, James R. Kincaid and Emily E. Weinert

Biochemistry, 2021, 60, 3801
DOI: 10.1021/acs.biochem.1c00581

Structural basis of CDNF interaction with the UPR regulator GRP78

Melissa A. Graewert, Maria Volkova, Klara Jonasson, Juha A. E. Määttä, Tobias Gräwert, Samara Mamidi, Natalia Kulesskaya, Johan Evenäs, Richard E. Johnsson, Dmitri Svergun, Arnab Bhattacharjee and Henri J. Huttunen

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-52478-0

Structural basis for the role of C-terminus acidic tail of Saccharomyces cerevisiae ubiquitin-conjugating enzyme (Rad6) in E3 ligase (Bre1) mediated recognition of histones

Pawan Yadav, Manish Gupta, Rushna Wazahat, Zeyaul Islam, Susan E. Tsutakawa, Mohan Kamthan and Pankaj Kumar

International Journal of Biological Macromolecules, 2024, 254, 127717
DOI: 10.1016/j.ijbiomac.2023.127717

Structural Features of a Full-Length Ubiquitin Ligase Responsible for the Formation of Patches at the Plasma Membrane

Jan Knop, Tim Lienemann, Haifa El-Kilani, Sven Falke, Catharina Krings, Maria Sindalovskaya, Johannes Bergler, Christian Betzel and Stefan Hoth

IJMS, 2021, 22, 9455
DOI: 10.3390/ijms22179455

Small-angle X-ray and neutron scattering

Cy M. Jeffries, Jan Ilavsky, Anne Martel, Stephan Hinrichs, Andreas Meyer, Jan Skov Pedersen, Anna V. Sokolova and Dmitri I. Svergun

Nat Rev Methods Primers, 2021, 1
DOI: 10.1038/s43586-021-00064-9

Oligomerization processes limit photoactivation and recovery of the orange carotenoid protein

Elena A. Andreeva, Stanisław Niziński, Adjélé Wilson, Matteo Levantino, Elke De Zitter, Rory Munro, Fernando Muzzopappa, Aurélien Thureau, Ninon Zala, Gotard Burdzinski, Michel Sliwa, Diana Kirilovsky, Giorgio Schirò and Jacques-Philippe Colletier

Biophysical Journal, 2022, 121, 2849
DOI: 10.1016/j.bpj.2022.07.004

Correlating Conformational Equilibria with Catalysis in the Electron Bifurcating EtfABCX of Thermotoga maritima

Daniel T. Murray, Xiaoxuan Ge, Gerrit J. Schut, Daniel J. Rosenberg, Michal Hammel, Jan C. Bierma, Russ Hille, Michael W. W. Adams and Greg L. Hura

Biochemistry, 2024, 63, 128
DOI: 10.1021/acs.biochem.3c00472

Recent developments in small-angle X-ray scattering and hybrid method approaches for biomacromolecular solutions

Marcellus Ubbink, Anastassis Perrakis, Martin A. Schroer and Dmitri I. Svergun

Emerging Topics in Life Sciences, 2018, 2, 69
DOI: 10.1042/ETLS20170138

Using normal mode analysis on protein structural models. How far can we go on our predictions?

Nuria Cirauqui Diaz, Elisa Frezza and Juliette Martin

Proteins, 2021, 89, 531
DOI: 10.1002/prot.26037

Structure and substrate specificity determinants of the taurine biosynthetic enzyme cysteine sulphinic acid decarboxylase

Elaheh Mahootchi, Arne Raasakka, Weisha Luan, Gopinath Muruganandam, Remy Loris, Jan Haavik and Petri Kursula

Journal of Structural Biology, 2021, 213, 107674
DOI: 10.1016/j.jsb.2020.107674

Reversible and irreversible fluorescence activity of the Enhanced Green Fluorescent Protein in pH: Insights for the development of pH-biosensors

Nathalia Vieira dos Santos, Carolina Falaschi Saponi, Timothy M. Ryan, Fernando L. Primo, Tamar L. Greaves and Jorge F.B. Pereira

International Journal of Biological Macromolecules, 2020, 164, 3474
DOI: 10.1016/j.ijbiomac.2020.08.224

Oxygen-selective regulation of cyclic di-GMP synthesis by a globin coupled sensor with a shortened linking domain modulates Shewanella sp. ANA-3 biofilm

Ariel Schuelke-Sanchez, Neela H. Yennawar and Emily E. Weinert

Journal of Inorganic Biochemistry, 2024, 252, 112482
DOI: 10.1016/j.jinorgbio.2024.112482

Crystal structure of an extracellular superoxide dismutase from Onchocerca volvulus and implications for parasite-specific drug development

Amr Moustafa, Markus Perbandt, Eva Liebau, Christian Betzel and Sven Falke

Acta Crystallogr F Struct Biol Commun, 2022, 78, 232
DOI: 10.1107/S2053230X22005350

Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2

Syed Arif Abdul Rehman, Lee A. Armstrong, Sven M. Lange, Yosua Adi Kristariyanto, Tobias W. Gräwert, Axel Knebel, Dmitri I. Svergun and Yogesh Kulathu

Molecular Cell, 2021, 81, 4176
DOI: 10.1016/j.molcel.2021.08.024

X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin

Camila Campos-Escamilla, Dritan Siliqi, Luis A. Gonzalez-Ramirez, Carmen Lopez-Sanchez, Jose Antonio Gavira and Abel Moreno

IJMS, 2021, 22, 13392
DOI: 10.3390/ijms222413392

Structure–Function Studies of the Antibiotic Target l,l-Diaminopimelate Aminotransferase from Verrucomicrobium spinosum Reveal an Unusual Oligomeric Structure

Anthony W. Weatherhead, Jennifer M. Crowther, Christopher R. Horne, Yanxiang Meng, David Coombes, Michael J. Currie, Serena A. J. Watkin, Lily E. Adams, Anutthaman Parthasarathy, Renwick C. J. Dobson and André O. Hudson

Biochemistry, 2020, 59, 2274
DOI: 10.1021/acs.biochem.0c00185

Adjuvant effect of mesoporous silica SBA-15 on anti-diphtheria and anti-tetanus humoral immune response

Aryene Góes Trezena, Pedro Leonidas Oseliero Filho, Luís Carlos Cides da Silva, Cristiano Luis Pinto Oliveira, José Luiz de Souza Lopes, Nayara da Silva Antonio, Viktor Fonseca Barbosa Dettmann, Milena Apetito Akamatsu, Tereza da Silva Martins, Orlando Garcia Ribeiro, Márcia Carvalho de Abreu Fantini, Osvaldo Augusto Sant'Anna and Milene Tino-De-Franco

Biologicals, 2022, 80, 18
DOI: 10.1016/j.biologicals.2022.10.001

PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ

Miguel Á. Casado-Combreras, Francisco Rivero-Rodríguez, Carlos A. Elena-Real, Dmitry Molodenskiy, Antonio Díaz-Quintana, Marlène Martinho, Guillaume Gerbaud, Katiuska González-Arzola, Adrián Velázquez-Campoy, Dmitri Svergun, Valérie Belle, Miguel A. De la Rosa and Irene Díaz-Moreno

Computational and Structural Biotechnology Journal, 2022, 20, 3695
DOI: 10.1016/j.csbj.2022.07.009

Electrochemical Small-Angle X-ray Scattering for Potential-Dependent Structural Analysis of Redox Enzymes

Noya Loew, Chika Miura, Chiaki Sawahara, Saki Otobe, Taku Ogura, Yuichi Takasaki, Hikari Watanabe, Isao Shitanda and Masayuki Itagaki

Langmuir, 2025, 41, 383
DOI: 10.1021/acs.langmuir.4c03661

Interdomain communication suppressing high intrinsic ATPase activity of Sse1 is essential for its co‐disaggregase activity with Ssa1

Vignesh Kumar, Joshua Jebakumar Peter, Amin Sagar, Arjun Ray, Mainak Pratim Jha, Mathieu E. Rebeaud, Satyam Tiwari, Pierre Goloubinoff, Fnu Ashish and Koyeli Mapa

The FEBS Journal, 2020, 287, 671
DOI: 10.1111/febs.15045

Structural and molecular comparison of bacterial and eukaryotic trigger factors

Fabian Ries, Yvonne Carius, Marina Rohr, Karin Gries, Sandro Keller, C. Roy D. Lancaster and Felix Willmund

Sci Rep, 2017, 7
DOI: 10.1038/s41598-017-10625-2

Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity

Dorothée Houry, Arne Raasakka, Eugenio Ferrario, Marc Niere, Ersilia Bifulco, Petri Kursula and Mathias Ziegler

Journal of Structural Biology, 2023, 215, 108004
DOI: 10.1016/j.jsb.2023.108004

Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering

Aldrex Munsayac, Wellington C. Leite, Jesse B. Hopkins, Ian Hall, Hugh M. O’Neill and Sarah C. Keane

Structure, 2025, 33, 728
DOI: 10.1016/j.str.2025.01.017

Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A

Tatu J.K. Haataja, Rafael C. Bernardi, Simon Lecointe, Romain Capoulade, Jean Merot and Ulla Pentikäinen

Structure, 2019, 27, 102
DOI: 10.1016/j.str.2018.09.007

Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein

Archit Garg, Roberto Orru, Weixiang Ye, Ute Distler, Jeremy E. Chojnacki, Maja Köhn, Stefan Tenzer, Carsten Sönnichsen and Eva Wolf

Journal of Biological Chemistry, 2019, 294, 16604
DOI: 10.1074/jbc.RA119.009845

High-Throughput Computation of Anharmonic Low-Frequency Protein Vibrations

Michael A. Sauer, Souvik Mondal, Madeline Cano and Matthias Heyden

J. Phys. Chem. B, 2025, 129, 10739
DOI: 10.1021/acs.jpcb.5c04622

On the function of TRAP substrate-binding proteins: Conformational variation of the sialic acid binding protein SiaP

Te-Rina J. King-Hudson, James S. Davies, Senwei Quan, Michael J. Currie, Zachary D. Tillett, Jack Copping, Santosh Panjikar, Rosmarie Friemann, Jane R. Allison, Rachel A. North and Renwick C.J. Dobson

Journal of Biological Chemistry, 2024, 300, 107851
DOI: 10.1016/j.jbc.2024.107851

Pyrrolizwillin, ein Einzigartiges Bakterielles Alkaloid, Gebildet durch eine Kombination aus Nichtribosomaler Peptidsynthetase und nicht‐Enzymatischer Dimerisierung

Juliana Effert, Margaretha Westphalen, Andrea Calderari, Yi‐Ming Shi, Isam Elamri, Soumaya Najah, Peter Grün, Yanyan Li, Arnaud Gruez, Kira J. Weissman and Helge B. Bode

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202411258

Methods, development and applications of small-angle X-ray scattering to characterize biological macromolecules in solution

Stefano Da Vela and Dmitri I. Svergun

Current Research in Structural Biology, 2020, 2, 164
DOI: 10.1016/j.crstbi.2020.08.004

High-affinity anti-Arc nanobodies provide tools for structural and functional studies

Sigurbjörn Markússon, Erik I. Hallin, Helene J. Bustad, Arne Raasakka, Ju Xu, Gopinath Muruganandam, Remy Loris, Aurora Martinez, Clive R. Bramham, Petri Kursula and Andreas Hofmann

PLoS ONE, 2022, 17, e0269281
DOI: 10.1371/journal.pone.0269281

Matrix proteins of enveloped viruses: a case study of Influenza A virus M1 protein

Larisa V. Kordyukova, Eleonora V. Shtykova, Lyudmila A. Baratova, Dmitri I. Svergun and Oleg V. Batishchev

Journal of Biomolecular Structure and Dynamics, 2019, 37, 671
DOI: 10.1080/07391102.2018.1436089

Legionella pneumophila macrophage infectivity potentiator protein appendage domains modulate protein dynamics and inhibitor binding

C. Wiedemann, J.J. Whittaker, V.H. Pérez Carrillo, B. Goretzki, M. Dajka, F. Tebbe, J.-M. Harder, P.R. Krajczy, B. Joseph, F. Hausch, A. Guskov and U.A. Hellmich

International Journal of Biological Macromolecules, 2023, 252, 126366
DOI: 10.1016/j.ijbiomac.2023.126366

Large conformational changes of a highly dynamic pre-protein binding domain in SecA

Isabel Ernst, Maximilian Haase, Stefan Ernst, Shuguang Yuan, Andreas Kuhn and Sebastian Leptihn

Commun Biol, 2018, 1
DOI: 10.1038/s42003-018-0133-4

An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis

Timothy M. Ryan, Jill Trewhella, James M. Murphy, Jeremy R. Keown, Lachlan Casey, F. Grant Pearce, David C. Goldstone, Kelan Chen, Zhenyao Luo, Bostjan Kobe, Christopher A. McDevitt, Serena A. Watkin, Adrian M. Hawley, Stephen T. Mudie, Vesna Samardzic Boban and Nigel Kirby

J Appl Crystallogr, 2018, 51, 97
DOI: 10.1107/S1600576717017101

Normal‐mode driven exploration of protein domain motions

Yves‐Henri Sanejouand

J Comput Chem, 2021, 42, 2250
DOI: 10.1002/jcc.26755

Study on internal structure of casein micelles in reconstituted skim milk powder

Zhongyao Du, Ning Xu, Ying Yang, Guimei Li, Zhonghong Tai, Na Li and Yang Sun

International Journal of Biological Macromolecules, 2023, 224, 437
DOI: 10.1016/j.ijbiomac.2022.10.135

Small-angle X-ray scattering profile calculation for high-resolution models of biomacromolecules

Kristian Lytje and Jan Skov Pedersen

J Appl Crystallogr, 2025, 58, 1332
DOI: 10.1107/S160057672500562X

Insights into dynamic changes in ADC-7 and P99 cephalosporinases using small angle x-ray scattering (SAXS)

Ish Kumar, Amin Sagar, Kanika Dhiman, Christopher R. Bethel, Andrea M. Hujer, Justin Carifi, Ashish and Robert A. Bonomo

Journal of Biomolecular Structure and Dynamics, 2024, 42, 7541
DOI: 10.1080/07391102.2023.2240427

Structural basis of cell wall peptidoglycan amidation by the GatD/MurT complex of Staphylococcus aureus

Erik R. Nöldeke, Lena M. Muckenfuss, Volker Niemann, Anna Müller, Elena Störk, Georg Zocher, Tanja Schneider and Thilo Stehle

Sci Rep, 2018, 8
DOI: 10.1038/s41598-018-31098-x

Structure–Activity Relationship of the Dimeric and Oligomeric Forms of a Cytotoxic Biotherapeutic Based on Diphtheria Toxin

Marcin Mielecki, Marcin Ziemniak, Magdalena Ozga, Radosław Borowski, Jarosław Antosik, Angelika Kaczyńska and Beata Pająk

Biomolecules, 2022, 12, 1111
DOI: 10.3390/biom12081111

Unlocking the secrets of SARS-CoV-2 nsp3 by combining experiments with AlphaFold2 domain prediction

Maximilian Edich, Yunyun Gao, David C Briggs and Andrea Thorn

Life Sci. Alliance, 2026, 9, e202503247
DOI: 10.26508/lsa.202503247

Structural insights into the role and targeting of EGFRvIII

Atrish Bagchi, Steven E. Stayrook, Katerina T. Xenaki, Chrystal A. Starbird, Sofia Doulkeridou, Rachid el Khoulati, Rob C. Roovers, Karl R. Schmitz, Paul M.P. van Bergen en Henegouwen and Kathryn M. Ferguson

Structure, 2024, 32, 1367
DOI: 10.1016/j.str.2024.05.018

The Structure of Saccharomyces cerevisiae Arginyltransferase 1 (ATE1)

Verna Van, Nna-Emeka Ejimogu, Toan S. Bui and Aaron T. Smith

Journal of Molecular Biology, 2022, 434, 167816
DOI: 10.1016/j.jmb.2022.167816

Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface

Angélica Luana C. Barra, Najeeb Ullah, Hévila Brognaro, Raissa F. Gutierrez, Carsten Wrenger, Christian Betzel and Alessandro S. Nascimento

Journal of Biological Chemistry, 2024, 300, 107404
DOI: 10.1016/j.jbc.2024.107404

ARL15, a GTPase implicated in rheumatoid arthritis, potentially repositions its truncated N-terminus as a function of guanine nucleotide binding

Manisha Saini, Neelam Upadhyay, Kanika Dhiman, Satish Kumar Manjhi, Aman Achutan Kattuparambil, Antara Ghoshal, Richa Arya, Sanjay Kumar Dey, Aditya Sharma, Raviprasad Aduri, B.K. Thelma, Fnu Ashish and Suman Kundu

International Journal of Biological Macromolecules, 2024, 254, 127898
DOI: 10.1016/j.ijbiomac.2023.127898

Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly

Serena A.J. Watkin, Jeremy R. Keown, Eric Richards, David C. Goldstone, Sean R.A. Devenish and F. Grant Pearce

Biochemical Journal, 2018, 475, 137
DOI: 10.1042/BCJ20170709

NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor

Kim Krighaar Rasmussen, Maria Hansen Falkesgaard, Malene Winther, Nikolaj Kulahin Roed, Christine Louise Quistgaard, Marie Nygaard Teisen, Sofie Marie Edslev, David Leander Petersen, Ali Aljubouri, Claus Christensen, Peter Waaben Thulstrup, Leila Lo Leggio, Kaare Teilum and Peter Schledermann Walmod

Sci Rep, 2018, 8
DOI: 10.1038/s41598-018-27089-7

A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies

Manickam Gurusaran and Owen Richard Davies

eLife, 2021, 10
DOI: 10.7554/eLife.60175

Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis

Amit Luthra, Jairo M. Montezuma-Rusca, Carson J. La Vake, Morgan LeDoyt, Kristina N. Delgado, Timothy C. Davenport, Mary Fiel-Gan, Melissa J. Caimano, Justin D. Radolf, Kelly L. Hawley and D. Scott Samuels

PLoS Pathog, 2020, 16, e1008871
DOI: 10.1371/journal.ppat.1008871

Recombinant AcnB, NrdR and RibD of Acinetobacter baumannii and their potential interaction with DNA adenine methyltransferase AamA

Kristin Weber, Joerg Doellinger, Cy M. Jeffries and Gottfried Wilharm

Protein Expression and Purification, 2022, 199, 106134
DOI: 10.1016/j.pep.2022.106134

Structural Plasticity within 3-Hydroxy-3-Methylglutaryl Synthases Catalyzing the First Step of β-Branching in Polyketide Biosynthesis Underpins a Dynamic Mechanism of Substrate Accommodation

Sabrina Collin, Kira J. Weissman and Arnaud Gruez

JACS Au, 2024, 4, 3833
DOI: 10.1021/jacsau.4c00477

Characterization of the OMP biogenesis machinery in Fusobacterium nucleatum

Claire Overly Cottom, Eva Heinz, Satchal Erramilli, Anthony Kossiakoff, Daniel J. Slade and Nicholas Noinaj

Structure, 2025, 33, 1878
DOI: 10.1016/j.str.2025.08.008

Structure and mechanism of a bacterial t6A biosynthesis system

Amit Luthra, William Swinehart, Susan Bayooz, Phuc Phan, Boguslaw Stec, Dirk Iwata-Reuyl and Manal A Swairjo

Nucleic Acids Research, 2018, 46, 1395
DOI: 10.1093/nar/gkx1300

Insights on lysozyme aggregation in protic ionic liquid solvents by using small angle X-ray scattering and high throughput screening

Qi Han, Jack Binns, Jiali Zhai, Xingyu Guo, Timothy M. Ryan, Calum J. Drummond and Tamar L. Greaves

Journal of Molecular Liquids, 2022, 345, 117816
DOI: 10.1016/j.molliq.2021.117816

Structure, aggregation dynamics and crystallization of superfolder green fluorescent protein: Effect of long alkyl chain imidazolium ionic liquids

Qi Han, Connie Darmanin, Carlos J. Rosado, Nathalia Vieira Veríssimo, Jorge F.B. Pereira, Gary Bryant, Calum J. Drummond and Tamar L. Greaves

International Journal of Biological Macromolecules, 2023, 253, 127456
DOI: 10.1016/j.ijbiomac.2023.127456

Unveiling the structure of the primary caseinate particle using small-angle X-ray scattering and simulation methodologies

Yang Sun, Zhonghong Tai, Tingting Yan, Yiqi Dai, Yacine Hemar and Na Li

Food Research International, 2021, 149, 110653
DOI: 10.1016/j.foodres.2021.110653

A THz transparent 3D printed microfluidic cell for small angle x-ray scattering

S. Schewa, M. A. Schroer, T. Zickmantel, Y.-H. Song, C. E. Blanchet, A. Yu. Gruzinov, G. Katona, D. I. Svergun and M. Roessle

Review of Scientific Instruments, 2020, 91
DOI: 10.1063/5.0004706

Structural Characterization of Functionally Important Chloride Binding Sites in the Marine Vibrio Alkaline Phosphatase

Sigurbjörn Markússon, Jens G. Hjörleifsson, Petri Kursula and Bjarni Ásgeirsson

Biochemistry, 2022, 61, 2248
DOI: 10.1021/acs.biochem.2c00438

Effect of ionic liquids on the fluorescence properties and aggregation of superfolder green fluorescence protein

Qi Han, Timothy M. Ryan, Carlos J. Rosado, Calum J. Drummond and Tamar L. Greaves

Journal of Colloid and Interface Science, 2021, 591, 96
DOI: 10.1016/j.jcis.2021.02.002

Molecular mechanism of cellulose depolymerization by the two-domain BlCel9A enzyme from the glycoside hydrolase family 9

Evandro Ares de Araújo, Anelyse Abreu Cortez, Vanessa de Oliveira Arnoldi Pellegrini, Milena Moreira Vacilotto, Amanda Freitas Cruz, Paulo Ricardo Batista and Igor Polikarpov

Carbohydrate Polymers, 2024, 329, 121739
DOI: 10.1016/j.carbpol.2023.121739

Structure and function of an atypical homodimeric actin capping protein from the malaria parasite

Ábris Ádám Bendes, Petri Kursula and Inari Kursula

Cell. Mol. Life Sci., 2022, 79
DOI: 10.1007/s00018-021-04032-0

Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments

Cy M Jeffries, Melissa A Graewert, Clément E Blanchet, David B Langley, Andrew E Whitten and Dmitri I Svergun

Nat Protoc, 2016, 11, 2122
DOI: 10.1038/nprot.2016.113

Structural Modeling Using Solution Small-Angle X-ray Scattering (SAXS)

Tobias W. Gräwert and Dmitri I. Svergun

Journal of Molecular Biology, 2020, 432, 3078
DOI: 10.1016/j.jmb.2020.01.030

Visualizing the nucleating and capped states of f-actin by Ca2+-gelsolin: Saxs data based structures of binary and ternary complexes

Amin Sagar, Nagesh Peddada, Vikas Choudhary, Yawar Mir, Renu Garg and Ashish

International Journal of Biological Macromolecules, 2024, 278, 134556
DOI: 10.1016/j.ijbiomac.2024.134556

Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase

Sina Reckel, Charlotte Gehin, Delphine Tardivon, Sandrine Georgeon, Tim Kükenshöner, Frank Löhr, Akiko Koide, Lena Buchner, Alejandro Panjkovich, Aline Reynaud, Sara Pinho, Barbara Gerig, Dmitri Svergun, Florence Pojer, Peter Güntert, Volker Dötsch, Shohei Koide, Anne-Claude Gavin and Oliver Hantschel

Nat Commun, 2017, 8
DOI: 10.1038/s41467-017-02313-6

Tailoring the NIR‐II Photoluminescence of Single Thiolated Au25 Nanoclusters by Selective Binding to Proteins**

Franck Bertorelle, K. David Wegner, Martina Perić Bakulić, Hussein Fakhouri, Clothilde Comby‐Zerbino, Amin Sagar, Pau Bernadó, Ute Resch‐Genger, Vlasta Bonačić‐Koutecký, Xavier Le Guével and Rodolphe Antoine

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202200570

TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life

Emma Davé, Oliver Durrant, Neha Dhami, Joanne Compson, Janice Broadbridge, Sophie Archer, Asher Maroof, Kevin Whale, Karelle Menochet, Pierre Bonnaillie, Emily Barry, Gavin Wild, Claude Peerboom, Pallavi Bhatta, Mark Ellis, Matthew Hinchliffe, David P. Humphreys and Sam P. Heywood

mAbs, 2023, 15
DOI: 10.1080/19420862.2022.2160229

Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation

Lori Buetow, Giancarlo Tria, Syed Feroj Ahmed, Andreas Hock, Hao Dou, Gary J. Sibbet, Dmitri I. Svergun and Danny T. Huang

BMC Biol, 2016, 14
DOI: 10.1186/s12915-016-0298-6

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

D. Franke, M. V. Petoukhov, P. V. Konarev, A. Panjkovich, A. Tuukkanen, H. D. T. Mertens, A. G. Kikhney, N. R. Hajizadeh, J. M. Franklin, C. M. Jeffries and D. I. Svergun

J Appl Crystallogr, 2017, 50, 1212
DOI: 10.1107/S1600576717007786

Probing ion-binding at a protein interface: Modulation of protein properties by ionic liquids

Qi Han, Yuyu Su, Kate M. Smith, Jack Binns, Calum J. Drummond, Connie Darmanin and Tamar L. Greaves

Journal of Colloid and Interface Science, 2023, 650, 1393
DOI: 10.1016/j.jcis.2023.07.045

Investigating the quaternary structure of a homomultimeric catechol 1,2-dioxygenase: An integrative structural biology study

Arisbeth Guadalupe Almeida-Juarez, Shirish Chodankar, Liliana Pardo-López, Guadalupe Zavala-Padilla, Enrique Rudiño-Piñera and Matteo De March

PLoS One, 2025, 20, e0315992
DOI: 10.1371/journal.pone.0315992

SASpy: a PyMOL plugin for manipulation and refinement of hybrid models against small angle X-ray scattering data

Alejandro Panjkovich and Dmitri I. Svergun

Bioinformatics, 2016, 32, 2062
DOI: 10.1093/bioinformatics/btw071

Lysozyme conformational changes with ionic liquids: Spectroscopic, small angle x-ray scattering and crystallographic study

Qi Han, Kate M. Smith, Connie Darmanin, Timothy M. Ryan, Calum J. Drummond and Tamar L. Greaves

Journal of Colloid and Interface Science, 2021, 585, 433
DOI: 10.1016/j.jcis.2020.10.024

On the function of TRAP substrate-binding proteins: the isethionate-specific binding protein IseP

Michael C. Newton-Vesty, Michael J. Currie, James S. Davies, Santosh Panjikar, Ashish Sethi, Andrew E. Whitten, Zachary D. Tillett, David M. Wood, Joshua D. Wright, Michael J. Love, Timothy M. Allison, Sam A. Jamieson, Peter D. Mace, Rachel A. North and Renwick C.J. Dobson

Biochemical Journal, 2024, 481, 1901
DOI: 10.1042/BCJ20240540

Reduction of small-angle scattering profiles to finite sets of structural invariants

Jérôme Houdayer and Frédéric Poitevin

Acta Crystallogr A Found Adv, 2017, 73, 317
DOI: 10.1107/S205327331700451X

The mechanism of complex formation between calmodulin and voltage gated calcium channels revealed by molecular dynamics

Shivani Yaduvanshi, Rya Ero, Veerendra Kumar and Eugene A. Permyakov

PLoS ONE, 2021, 16, e0258112
DOI: 10.1371/journal.pone.0258112

Solution scattering approaches to dynamical ordering in biomolecular systems

Pau Bernadó, Nobutaka Shimizu, Giuseppe Zaccai, Hironari Kamikubo and Masaaki Sugiyama

Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862, 253
DOI: 10.1016/j.bbagen.2017.10.015

Signaling ammonium across membranes through an ammonium sensor histidine kinase

Tobias Pflüger, Camila F. Hernández, Philipp Lewe, Fabian Frank, Haydyn Mertens, Dmitri Svergun, Manfred W. Baumstark, Vladimir Y. Lunin, Mike S. M. Jetten and Susana L. A. Andrade

Nat Commun, 2018, 9
DOI: 10.1038/s41467-017-02637-3

Global shape of SvGT, a metal-dependent bacteriocin modifying S/O-HexNActransferase from actinobacteria: c -terminal dimerization modulates the function of this GT

Yogita Sharma, Shimona Ahlawat, Ashish and Alka Rao

Journal of Biomolecular Structure and Dynamics, 2024, 42, 10150
DOI: 10.1080/07391102.2023.2255906

Disease-associated mutations alter the dynamic motion of the N-terminal domain of the human cardiac ryanodine receptor

Jacob A. Bauer, Ľubomír Borko, Jelena Pavlović, Eva Kutejová and Vladena Bauerová-Hlinková

Journal of Biomolecular Structure and Dynamics, 2020, 38, 1054
DOI: 10.1080/07391102.2019.1600027

Crystal structure of the phospholipase A and acyltransferase 4 (PLAAT4) catalytic domain

Anna Wehlin, Irina Cornaciu, José Antonio Marquez, Anastassis Perrakis and Eleonore von Castelmur

Journal of Structural Biology, 2022, 214, 107903
DOI: 10.1016/j.jsb.2022.107903

PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi

Ashley M. Groshong, André A. Grassmann, Amit Luthra, Melissa A. McLain, Anthony A. Provatas, Justin D. Radolf, Melissa J. Caimano and Jenifer Coburn

PLoS Pathog, 2021, 17, e1009725
DOI: 10.1371/journal.ppat.1009725

Atypical Domain Communication and Domain Functions of a Hsp110 Chaperone

Vignesh Kumar, Joshua Jebakumar Peter, Amin Sagar, Arjun Ray and Koyeli Mapa

SSRN Journal, 2018
DOI: 10.2139/ssrn.3155865

Scattering approaches to unravel protein solution behaviors in ionic liquids and deep eutectic solvents: From basic principles to recent developments

Qi Han, Nathalia V.P. Veríssimo, Saffron J. Bryant, Andrew V. Martin, Yuhong Huang, Jorge F.B. Pereira, Valéria C. Santos-Ebinuma, Jiali Zhai, Gary Bryant, Calum J. Drummond and Tamar L. Greaves

Advances in Colloid and Interface Science, 2024, 331, 103242
DOI: 10.1016/j.cis.2024.103242

ATSAS 3.0: expanded functionality and new tools for small-angle scattering data analysis

Karen Manalastas-Cantos, Petr V. Konarev, Nelly R. Hajizadeh, Alexey G. Kikhney, Maxim V. Petoukhov, Dmitry S. Molodenskiy, Alejandro Panjkovich, Haydyn D. T. Mertens, Andrey Gruzinov, Clemente Borges, Cy M. Jeffries, Dmitri I. Svergun and Daniel Franke

J Appl Crystallogr, 2021, 54, 343
DOI: 10.1107/S1600576720013412

Recombinant production of A1S_0222 from Acinetobacter baumannii ATCC 17978 and confirmation of its DNA-(adenine N6)-methyltransferase activity

Ulrike Blaschke, Beneditta Suwono, Sachli Zafari, Ingo Ebersberger, Evelyn Skiebe, Cy M. Jeffries, Dmitri I. Svergun and Gottfried Wilharm

Protein Expression and Purification, 2018, 151, 78
DOI: 10.1016/j.pep.2018.06.009

A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15

Pedro De-la-Torre, Deepanshu Choudhary, Raul Araya-Secchi, Yoshie Narui and Marcos Sotomayor

Biophysical Journal, 2018, 115, 2368
DOI: 10.1016/j.bpj.2018.11.010

Pyrrolizwilline, a Unique Bacterial Alkaloid Assembled by a Nonribosomal Peptide Synthetase and non‐Enzymatic Dimerization

Juliana Effert, Margaretha Westphalen, Andrea Calderari, Yi‐Ming Shi, Isam Elamri, Soumaya Najah, Peter Grün, Yanyan Li, Arnaud Gruez, Kira J. Weissman and Helge B. Bode

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202411258

Martini bead form factors for nucleic acids and their application in the refinement of protein–nucleic acid complexes against SAXS data

Cristina Paissoni, Alexander Jussupow and Carlo Camilloni

J Appl Crystallogr, 2019, 52, 394
DOI: 10.1107/S1600576719002450

New open conformation of SMYD3 implicates conformational selection and allostery

Nicholas Spellmon, Xiaonan Sun, Wen Xue, Joshua Holcomb, Srinivas Chakravarthy, Weifeng Shang, Brian Edwards, Nualpun Sirinupong, Chunying Li and Zhe Yang

AIMS Biophysics, 2016, 4, 1
DOI: 10.3934/biophy.2017.1.1

Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A

Baisen Zeng, Tung-Chung Mou, Tzanko I. Doukov, Andrea Steiner, Wenxi Yu, Makaia Papasergi-Scott, Gregory G. Tall, Franz Hagn and Stephen R. Sprang

Structure, 2019, 27, 1137
DOI: 10.1016/j.str.2019.04.013

Sampling globally and locally correct RNA 3D structures using Ernwin, SPQR and experimental SAXS data

Bernhard C Thiel, Giovanni Bussi, Simón Poblete and Ivo L Hofacker

Nucleic Acids Research, 2024, 52, e73
DOI: 10.1093/nar/gkae602

Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

Levi J. McClelland, Kaiming Zhang, Tung-Chung Mou, Jake Johnston, Cindee Yates-Hansen, Shanshan Li, Celestine J. Thomas, Tzanko I. Doukov, Sarah Triest, Alexandre Wohlkonig, Gregory G. Tall, Jan Steyaert, Wah Chiu and Stephen R. Sprang

Nat Commun, 2020, 11
DOI: 10.1038/s41467-020-14943-4

Structural interpretations of a flexible cold-active AMS8 lipase by combining small-angle X-ray scattering and molecular dynamics simulation (SAXS-MD)

Norhayati Yaacob, Nuntaporn Kamonsutthipaijit, Siriwat Soontaranon, Thean Chor Leow, Raja Noor Zaliha Raja Abd Rahman and Mohd Shukuri Mohamad Ali

International Journal of Biological Macromolecules, 2022, 220, 1095
DOI: 10.1016/j.ijbiomac.2022.08.145

Despite the odds: formation of the SARS-CoV-2 methylation complex

Alex Matsuda, Jacek Plewka, Michał Rawski, André Mourão, Weronika Zajko, Till Siebenmorgen, Leanid Kresik, Kinga Lis, Alisha N Jones, Magdalena Pachota, Abdulkarim Karim, Kinga Hartman, Shivlee Nirwal, Ravi Sonani, Yuliya Chykunova, Igor Minia, Paweł Mak, Markus Landthaler, Marcin Nowotny, Grzegorz Dubin, Michael Sattler, Piotr Suder, Grzegorz M Popowicz, Krzysztof Pyrć and Anna Czarna

Nucleic Acids Research, 2024, 52, 6441
DOI: 10.1093/nar/gkae165

Integrative Structural Characterization of Candida glabrata Phosphoglycerate Kinase by Small-Angle X-ray Scattering and AlphaFold: Implications for Therapeutic Targeting in Candidiasis

Mayra Cuéllar-Cruz, Edson E. Maqueda Cabrera, Dritan Siliqi and Abel Moreno

ACS Omega, 2026, 11, 6628
DOI: 10.1021/acsomega.5c11751

Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases

Raphael Dos Santos Morais, Paulo E. Santo, Marie Ley, Cédric Schelcher, Yoann Abel, Laura Plassart, Evolène Deslignière, Marie-Eve Chagot, Marc Quinternet, Ana C.F. Paiva, Steve Hessmann, Nelly Morellet, Pedro M. F. Sousa, Franck Vandermoere, Edouard Bertrand, Bruno Charpentier, Tiago M. Bandeiras, Célia Plisson-Chastang, Céline Verheggen, Sarah Cianférani and Xavier Manival

Journal of Molecular Biology, 2022, 434, 167760
DOI: 10.1016/j.jmb.2022.167760

Acyl chains stabilize the acylated domain and determine the receptor-mediated interaction of the Bordetella adenylate cyclase toxin with cell membrane

Carlos Espinosa-Vinals, Jan Stransky, Radim Osicka, Adriana Osickova, David Jurnecka, Peter Sebo and Ladislav Bumba

Journal of Biological Chemistry, 2025, 301, 110392
DOI: 10.1016/j.jbc.2025.110392

Structural features of NS3 ofDengue virusserotypes 2 and 4 in solution and insight into RNA binding and the inhibitory role of quercetin

Ankita Pan, Wuan Geok Saw, Malathy Sony Subramanian Manimekalai, Ardina Grüber, Shin Joon, Tsutomu Matsui, Thomas M. Weiss and Gerhard Grüber

Acta Crystallogr D Struct Biol, 2017, 73, 402
DOI: 10.1107/S2059798317003849

Insights on the structure of caseinate particles based on surfactants-induced dissociation

Feng Cao, Yuanyuan Xia, Dan Chen, Ning Xu, Yacine Hemar, Na Li and Yang Sun

Food Hydrocolloids, 2020, 104, 105766
DOI: 10.1016/j.foodhyd.2020.105766

Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane

Si Hoon Park, Juhyun Han, Byung-Cheon Jeong, Ju Han Song, Se Hwan Jang, Hyeongseop Jeong, Bong Heon Kim, Young-Gyu Ko, Zee-Yong Park, Kyung Eun Lee, Jaekyung Hyun and Hyun Kyu Song

Nat Struct Mol Biol, 2023, 30, 1695
DOI: 10.1038/s41594-023-01111-7

Response regulator PorX coordinates oligonucleotide signalling and gene expression to control the secretion of virulence factors

Claus Schmitz, Mariusz Madej, Zuzanna Nowakowska, Anna Cuppari, Anna Jacula, Miroslaw Ksiazek, Katarzyna Mikruta, Jerzy Wisniewski, Natalia Pudelko-Malik, Anshu Saran, Natalie Zeytuni, Piotr Mlynarz, Richard J Lamont, Isabel Usón, Virginijus Siksnys, Jan Potempa and Maria Solà

Nucleic Acids Research, 2022, 50, 12558
DOI: 10.1093/nar/gkac1103

The Shigella Virulence Factor IcsA Relieves N-WASP Autoinhibition by Displacing the Verprolin Homology/Cofilin/Acidic (VCA) Domain

Rui P.M. Mauricio, Cy M. Jeffries, Dmitri I. Svergun and Janet E. Deane

Journal of Biological Chemistry, 2017, 292, 134
DOI: 10.1074/jbc.M116.758003

Structural changes of ovalbumin under alkaline-thermal induction and its gelation mechanism

Shende Hu, Xiaochen Liu, Jun Sun, Xiaosan Wang, Lulu Guo, Luping Gu, Cuihua Chang, Junhua Li, Yanjun Yang and Yujie Su

International Journal of Biological Macromolecules, 2026, 354, 151364
DOI: 10.1016/j.ijbiomac.2026.151364

Structure and Dynamics of a Promiscuous Xanthan Lyase from Paenibacillus nanensis and the Design of Variants with Increased Stability and Activity

Pernille Foged Jensen, Anders Kadziola, Gerard Comamala, Dorotea R. Segura, Lars Anderson, Jens-Christian N. Poulsen, Kim Krighaar Rasmussen, Shilpi Agarwal, Rajendra K. Sainathan, Rune Nygaard Monrad, Allan Svendsen, Jens Erik Nielsen, Leila Lo Leggio and Kasper D. Rand

Cell Chemical Biology, 2019, 26, 191
DOI: 10.1016/j.chembiol.2018.10.016

Dynamics and conformational propensities of staphylococcal CntA

Zain Ul Abideen, Ashfaq Ahmad, Muhammad Usman, Sidra Majaz, Waqar Ali, Shumaila Noreen, Tariq Mahmood and Faisal Nouroz

Journal of Biomolecular Structure and Dynamics, 2021, 39, 4923
DOI: 10.1080/07391102.2020.1782263

Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S

Beatriz Trastoy, Erik Klontz, Jared Orwenyo, Alberto Marina, Lai-Xi Wang, Eric J. Sundberg and Marcelo E. Guerin

Nat Commun, 2018, 9
DOI: 10.1038/s41467-018-04300-x

Shape–function insights into bifunctional O-GlcNActransferase of Listeria monocytogenes EGD-e

Pravinkumar Choudhary, Maulik D Badmalia and Alka Rao

Glycobiology, 2021, 31, 275
DOI: 10.1093/glycob/cwaa076

REC domain stabilizes the active heptamer of σ54-dependent transcription factor, FleR from Pseudomonas aeruginosa

Pankaj Kumar Sahoo, Sheenu and Deepti Jain

iScience, 2023, 26, 108397
DOI: 10.1016/j.isci.2023.108397

Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor

Nathanael A. Caveney, Anja Pavlin, Guillermo Caballero, Miha Bahun, Vesna Hodnik, Liza de Castro, Nadine Fornelos, Matej Butala and Natalie C.J. Strynadka

Structure, 2019, 27, 1094
DOI: 10.1016/j.str.2019.03.019

The allosteric modulation of complement C5 by knob domain peptides

Alex Macpherson, Maisem Laabei, Zainab Ahdash, Melissa A Graewert, James R Birtley, Monika-Sarah ED Schulze, Susan Crennell, Sarah A Robinson, Ben Holmes, Vladas Oleinikovas, Per H Nilsson, James Snowden, Victoria Ellis, Tom Eirik Mollnes, Charlotte M Deane, Dmitri Svergun, Alastair DG Lawson and Jean MH van den Elsen

eLife, 2021, 10
DOI: 10.7554/eLife.63586

Small angle X-ray scattering analysis of thermophilic cytochrome P450 CYP119 and the effects of the N-terminal histidine tag

Ekin Kestevur Doğru, Tuğçe Sakallı, Goksin Liu, Zehra Sayers and Nur Basak Surmeli

International Journal of Biological Macromolecules, 2024, 265, 131026
DOI: 10.1016/j.ijbiomac.2024.131026

Recent Progress in Solution Structure Studies of Photosynthetic Proteins Using Small-Angle Scattering Methods

Maksym Golub and Jörg Pieper

Molecules, 2023, 28, 7414
DOI: 10.3390/molecules28217414

N-terminal half of transportin SR2 interacts with HIV integrase

Vicky G. Tsirkone, Jolien Blokken, Flore De Wit, Jolien Breemans, Stéphanie De Houwer, Zeger Debyser, Frauke Christ and Sergei V. Strelkov

Journal of Biological Chemistry, 2017, 292, 9699
DOI: 10.1074/jbc.M117.777029

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein

Mariana Sacerdoti, Lissy Z. F. Gross, Andrew M. Riley, Karin Zehnder, Abhijeet Ghode, Sebastián Klinke, Ganesh Srinivasan Anand, Kristina Paris, Angelika Winkel, Amanda K. Herbrand, H. Yasmin Godage, Gyles E. Cozier, Evelyn Süß, Jörg O. Schulze, Daniel Pastor-Flores, Mariela Bollini, María Victoria Cappellari, Dmitri Svergun, Melissa A. Gräwert, Pedro F. Aramendia, Alejandro E. Leroux, Barry V. L. Potter, Carlos J. Camacho and Ricardo M. Biondi

Sci. Signal., 2023, 16
DOI: 10.1126/scisignal.add3184

A small angle X-ray scattering study comparing protic ionic liquid solvent effects on the solution behaviors of hen egg white and human lysozyme

Stuart J. Brown, Calum J. Drummond, Tamar L. Greaves and Qi Han

Journal of Molecular Liquids, 2024, 404, 124970
DOI: 10.1016/j.molliq.2024.124970

Protic Ionic Liquid Cation Alkyl Chain Length Effect on Lysozyme Structure

Qi Han, Hayden C. Broomhall, Nathalia Vieira Veríssimo, Timothy M. Ryan, Calum J. Drummond, Jorge F. B. Pereira and Tamar L. Greaves

Molecules, 2022, 27, 984
DOI: 10.3390/molecules27030984

Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility

Christian M. Orr, Hayden Fisher, Xiaojie Yu, Claude H.-T. Chan, Yunyun Gao, Patrick J. Duriez, Steven G. Booth, Isabel Elliott, Tatyana Inzhelevskaya, Ian Mockridge, Christine A. Penfold, Armin Wagner, Martin J. Glennie, Ann L. White, Jonathan W. Essex, Arwen R. Pearson, Mark S. Cragg and Ivo Tews

Sci. Immunol., 2022, 7
DOI: 10.1126/sciimmunol.abm3723

Matthias Fellner, George Randall, Ianah R. C. G. Bitac, Annmaree K. Warrender, Ashish Sethi, Raz Jelinek and Itamar Kass

Proteins, 2025, 93, 1009
DOI: 10.1002/prot.26785

Structural and biophysical insights into RomR, MglB, and MglC interactions involved in regulating cell polarity in Myxococcus xanthus

Akriti Kodesia, Srajan Kapoor and Krishan Gopal Thakur

Journal of Biological Chemistry, 2025, 301, 110907
DOI: 10.1016/j.jbc.2025.110907

Heme pocket modulates protein conformation and diguanylate cyclase activity of a tetrameric globin coupled sensor

Jacob R. Potter, Shannon Rivera, Paul G. Young, Dayna C. Patterson, Kevin E. Namitz, Neela Yennawar, James R. Kincaid, Yilin Liu and Emily E. Weinert

Journal of Inorganic Biochemistry, 2024, 258, 112638
DOI: 10.1016/j.jinorgbio.2024.112638

Biophysical analysis of Arabidopsis protein-only RNase P alone and in complex with tRNA provides a refined model of tRNA binding

Franziska Pinker, Cédric Schelcher, Pablo Fernandez-Millan, Anthony Gobert, Catherine Birck, Aurélien Thureau, Pierre Roblin, Philippe Giegé and Claude Sauter

Journal of Biological Chemistry, 2017, 292, 13904
DOI: 10.1074/jbc.M117.782078

Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20

Ana Rita Otrelo-Cardoso, Rashmi R. Nair, Márcia A. S. Correia, Raquel S. Correia Cordeiro, Alejandro Panjkovich, Dmitri I. Svergun, Teresa Santos-Silva and Maria G. Rivas

Sci Rep, 2017, 7
DOI: 10.1038/s41598-017-06133-y

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2

Tânia F. Custódio, Hrishikesh Das, Daniel J. Sheward, Leo Hanke, Samuel Pazicky, Joanna Pieprzyk, Michèle Sorgenfrei, Martin A. Schroer, Andrey Yu. Gruzinov, Cy M. Jeffries, Melissa A. Graewert, Dmitri I. Svergun, Nikolay Dobrev, Kim Remans, Markus A. Seeger, Gerald M. McInerney, Ben Murrell, B. Martin Hällberg and Christian Löw

Nat Commun, 2020, 11
DOI: 10.1038/s41467-020-19204-y

SAXS analysis of the intrinsic tenase complex bound to a lipid nanodisc highlights intermolecular contacts between factors VIIIa/IXa

Kenneth C. Childers, Shaun C. Peters, Pete Lollar, Harold Trent Spencer, Christopher B. Doering and Paul C. Spiegel

Blood Advances, 2022, 6, 3240
DOI: 10.1182/bloodadvances.2021005874

Probing the existence of non-thermal Terahertz radiation induced changes of the protein solution structure

Martin A. Schroer, Siawosch Schewa, Andrey Yu. Gruzinov, Christian Rönnau, Janine Mia Lahey-Rudolph, Clement E. Blanchet, Till Zickmantel, Young-Hwa Song, Dmitri I. Svergun and Manfred Roessle

Sci Rep, 2021, 11
DOI: 10.1038/s41598-021-01774-6