Nickel-responsive regulation of two novelHelicobacter pyloriNikR-targeted genes

M. D. Jones, I. Ademi, X. Yin, Y. Gong and D. B. Zamble

Metallomics, 2015, 7, 662
DOI: 10.1039/C4MT00210E

Novel insights into nickel import in Staphylococcus aureus: the positive role of free histidine and structural characterization of a new thiazolidine-type nickel chelator

H. Lebrette, E. Borezée-Durant, L. Martin, P. Richaud, E. Boeri Erba and C. Cavazza

Metallomics, 2015, 7, 613
DOI: 10.1039/C4MT00295D

Rhizobium leguminosarum HupE is a highly-specific diffusion facilitator for nickel uptake

Marta Albareda, Agnès Rodrigue, Belén Brito, Tomás Ruiz-Argüeso, Juan Imperial, Marie-Andrée Mandrand-Berthelot and Jose Palacios

Metallomics, 2015, 7, 691
DOI: 10.1039/C4MT00298A

Cu binding by the Escherichia coli metal-efflux accessory protein RcnB

Camille Blériot, Manon Gault, Erwan Gueguen, Pascal Arnoux, David Pignol, Marie-Andrée Mandrand-Berthelot and Agnès Rodrigue

Metallomics, 2014, 6, 1400
DOI: 10.1039/C4MT00036F

Ni2+chemistry in pathogens – a possible target for eradication

Magdalena Rowinska-Zyrek, Jolanta Zakrzewska-Czerwinska, Anna Zawilak-Pawlik and Henryk Kozlowski

Dalton Trans., 2014, 43, 8976
DOI: 10.1039/C4DT00421C

The impact of species, respiration type, growth phase and genetic inventory on absolute metal content of intact bacterial cells

Rohit Budhraja, Chang Ding, Philipp Walter, Stephan Wagner, Thorsten Reemtsma, R Gary Sawers and Lorenz Adrian

Metallomics, 2019, 11, 925
DOI: 10.1039/c9mt00009g

Nickel recognition by bacterial importer proteins

Peter T. Chivers

Metallomics, 2015, 7, 590
DOI: 10.1039/C4MT00310A

Elucidation of the biosynthesis of the methane catalyst coenzyme F430

Simon J. Moore, Sven T. Sowa, Christopher Schuchardt, Evelyne Deery, Andrew D. Lawrence, José Vazquez Ramos, Susan Billig, Claudia Birkemeyer, Peter T. Chivers, Mark J. Howard, Stephen E. J. Rigby, Gunhild Layer and Martin J. Warren

Nature, 2017, 543, 78
DOI: 10.1038/nature21427

Chalkophores

Grace E. Kenney and Amy C. Rosenzweig

Annu. Rev. Biochem., 2018, 87, 645
DOI: 10.1146/annurev-biochem-062917-012300

Metal Preferences and Metallation

Andrew W. Foster, Deenah Osman and Nigel J. Robinson

Journal of Biological Chemistry, 2014, 289, 28095
DOI: 10.1074/jbc.R114.588145

The Staphylococcus aureusOpp1 ABC transporter imports nickel and cobalt in zinc‐depleted conditions and contributes to virulence

Laetitia Remy, Marie Carrière, Aurélie Derré‐Bobillot, Cécilia Martini, Maurizio Sanguinetti and Elise Borezée‐Durant

Molecular Microbiology, 2013, 87, 730
DOI: 10.1111/mmi.12126

Geochemical, metagenomic and metaproteomic insights into trace metal utilization by methane‐oxidizing microbial consortia in sulphidic marine sediments

Jennifer B. Glass, Hang Yu, Joshua A. Steele, Katherine S. Dawson, Shulei Sun, Karuna Chourey, Chongle Pan, Robert L. Hettich and Victoria J. Orphan

Environmental Microbiology, 2014, 16, 1592
DOI: 10.1111/1462-2920.12314

Microbial nickel: cellular uptake and delivery to enzyme centers

Conor J Zeer-Wanklyn and Deborah B Zamble

Current Opinion in Chemical Biology, 2017, 37, 80
DOI: 10.1016/j.cbpa.2017.01.014

Direct Detection of the Labile Nickel Pool in Escherichia coli: New Perspectives on Labile Metal Pools

Hayley N. Brawley and Paul A. Lindahl

J. Am. Chem. Soc., 2021, 143, 18571
DOI: 10.1021/jacs.1c08213

An overview of the biological metal uptake pathways in Pseudomonas aeruginosa

Isabelle J. Schalk and Olivier Cunrath

Environmental Microbiology, 2016, 18, 3227
DOI: 10.1111/1462-2920.13525

Bacterial sensors define intracellular free energies for correct enzyme metalation

Deenah Osman, Maria Alessandra Martini, Andrew W. Foster, Junjun Chen, Andrew J. P. Scott, Richard J. Morton, Jonathan W. Steed, Elena Lurie-Luke, Thomas G. Huggins, Andrew D. Lawrence, Evelyne Deery, Martin J. Warren, Peter T. Chivers and Nigel J. Robinson

Nat Chem Biol, 2019, 15, 241
DOI: 10.1038/s41589-018-0211-4

Cadmium thiosulfate complexes can be assimilated by a green alga via a sulfate transporter but do not increase Cd toxicity

Frédéric Boily, Claude Fortin, Peter G. C. Campbell and Kevin Wilkinson

Environmental Chemistry, 2022, 19, 167
DOI: 10.1071/EN22038

Structural insights into the ligand recognition and catalysis of the key aminobutanoyltransferase CntL in staphylopine biosynthesis

Zhiteng Luo, Siting Luo, Yingchen Ju, Peng Ding, Jun Xu, Qiong Gu and Huihao Zhou

The FASEB Journal, 2021, 35
DOI: 10.1096/fj.202002287RR

Biochemical studies highlight determinants for metal selectivity in the Escherichia coli periplasmic solute binding protein NikA

Wayne W H Law, Voula Kanelis and Deborah B Zamble

Metallomics, 2022, 14
DOI: 10.1093/mtomcs/mfac084

Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes

David Sychantha, Xuefei Chen, Kalinka Koteva, Gerd Prehna and Gerard D. Wright

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-48232-1

Low-molecular-mass labile metal pools in Escherichia coli: advances using chromatography and mass spectrometry

Hayley N. Brawley and Paul A. Lindahl

J Biol Inorg Chem, 2021, 26, 479
DOI: 10.1007/s00775-021-01864-w

Characterization in Helicobacter pylori of a Nickel Transporter Essential for Colonization That Was Acquired during Evolution by Gastric Helicobacter Species

Frédéric Fischer, Marie Robbe-Saule, Evelyne Turlin, Francesco Mancuso, Valérie Michel, Pierre Richaud, Frédéric J. Veyrier, Hilde De Reuse, Daniel Vinella and Andreas J Baumler

PLoS Pathog, 2016, 12, e1006018
DOI: 10.1371/journal.ppat.1006018

An investigation of inter-ligand coordination and flexibility: IRMPD spectroscopic and theoretical evaluation of calcium and nickel histidine dimers

Brandon C. Stevenson, Katrin Peckelsen, Jonathan Martens, Giel Berden, Jos Oomens, Mathias Schäfer and P.B. Armentrout

Journal of Molecular Spectroscopy, 2021, 381, 111532
DOI: 10.1016/j.jms.2021.111532

In vitro maturation of NiSOD reveals a role for cytoplasmic histidine in processing and metalation

Priyanka Basak, Diane E Cabelli, Peter T Chivers, Erik R Farquhar and Michael J Maroney

Metallomics, 2023, 15
DOI: 10.1093/mtomcs/mfad054

Helicobacter pylori periplasmic receptor CeuE (HP1561) modulates its nickel affinity via organic metallophores

Md Munan Shaik, Laura Cendron, Marco Salamina, Maria Ruzzene and Giuseppe Zanotti

Molecular Microbiology, 2014, 91, 724
DOI: 10.1111/mmi.12487

Mechanism of Selective Nickel Transfer from HypB to HypA, Escherichia coli [NiFe]-Hydrogenase Accessory Proteins

Michael J. Lacasse, Colin D. Douglas and Deborah B. Zamble

Biochemistry, 2016, 55, 6821
DOI: 10.1021/acs.biochem.6b00706

Ni(II) Sensing by RcnR Does Not Require an FrmR-Like Intersubunit Linkage

Hsin-Ting Huang and Michael J. Maroney

Inorg. Chem., 2019, 58, 13639
DOI: 10.1021/acs.inorgchem.9b01096

Role of Nickel in Microbial Pathogenesis

Robert Maier and Stéphane Benoit

Inorganics, 2019, 7, 80
DOI: 10.3390/inorganics7070080

Transport of nickel and cobalt ions into bacterial cells by S components of ECF transporters

Franziska Kirsch and Thomas Eitinger

Biometals, 2014, 27, 653
DOI: 10.1007/s10534-014-9738-3

Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus

Ghassan Ghssein, Catherine Brutesco, Laurent Ouerdane, Clémentine Fojcik, Amélie Izaute, Shuanglong Wang, Christine Hajjar, Ryszard Lobinski, David Lemaire, Pierre Richaud, Romé Voulhoux, Akbar Espaillat, Felipe Cava, David Pignol, Elise Borezée-Durant and Pascal Arnoux

Science, 2016, 352, 1105
DOI: 10.1126/science.aaf1018

Promiscuous Nickel Import in Human Pathogens: Structure, Thermodynamics, and Evolution of Extracytoplasmic Nickel-Binding Proteins

Hugo Lebrette, Céline Brochier-armanet, Barbara Zambelli, Hilde de Reuse, Elise Borezée-Durant, Stefano Ciurli and Christine Cavazza

Structure, 2014, 22, 1421
DOI: 10.1016/j.str.2014.07.012

The Pseudomonas aeruginosa PA14 ABC Transporter NppA1A2BCD Is Required for Uptake of Peptidyl Nucleoside Antibiotics

Daniel Pletzer, Yvonne Braun, Svetlana Dubiley, Corinne Lafon, Thilo Köhler, Malcolm G. P. Page, Michael Mourez, Konstantin Severinov, Helge Weingart and A. M. Stock

J. Bacteriol., 2015, 197, 2217
DOI: 10.1128/JB.00234-15

One His, two His…the emerging roles of histidine in cellular nickel trafficking

Peter T. Chivers, Priyanka Basak and Michael J. Maroney

Journal of Inorganic Biochemistry, 2024, 259, 112668
DOI: 10.1016/j.jinorgbio.2024.112668

Structural investigations connect the disordered N‐terminal extension of HypB to the activities of HypB and SlyD in E. coli

Wayne W. H. Law, Dmitry Pichugin, Ranjith Muhandiram, Deborah B. Zamble and Voula Kanelis

Protein Science, 2025, 34
DOI: 10.1002/pro.70231

Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance

Andrew S. Bray, Christopher A. Broberg, Andrew W. Hudson, Weisheng Wu, Ravinder K. Nagpal, Maidul Islam, Juan D. Valencia-Bacca, Fawaz Shahid, Giovanna E. Hernandez, Noah A. Nutter, Kimberly A. Walker, Emma F. Bennett, Taylor M. Young, Andrew J. Barnes, David A. Ornelles, Virginia L. Miller and M. Ammar Zafar

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-56309-8

The biosynthesis of methanobactin

Grace E. Kenney, Laura M. K. Dassama, Maria-Eirini Pandelia, Anthony S. Gizzi, Ryan J. Martinie, Peng Gao, Caroline J. DeHart, Luis F. Schachner, Owen S. Skinner, Soo Y. Ro, Xiao Zhu, Monica Sadek, Paul M. Thomas, Steven C. Almo, J. Martin Bollinger, Carsten Krebs, Neil L. Kelleher and Amy C. Rosenzweig

Science, 2018, 359, 1411
DOI: 10.1126/science.aap9437

The Extracellular Metallometabolome: Metallophores, Metal Ionophores, and Other Chelating Agents as Natural Products

Wolfgang Maret

Natural Product Communications, 2024, 19
DOI: 10.1177/1934578X241271701

Bacterial iron acquisition by Escherichia coli is facilitated by amino acid complexation in a rapid-renewal environment

Juanita Lara-Gutiérrez, Jen Nguyen, Matthew R. McIlvin, Ichiko Sugiyama, Zachary C. Landry, Uria Alcolombri, Sammy Pontrelli, Joaquín Jiménez-Martínez, Uwe Sauer, Terence Hwa, Johannes M. Keegstra, Mak A. Saito and Roman Stocker

Proc. Natl. Acad. Sci. U.S.A., 2026, 123
DOI: 10.1073/pnas.2520431123

EcNikA, a versatile tool in the field of artificial metalloenzymes

Caroline Marchi-Delapierre, Christine Cavazza and Stéphane Ménage

Journal of Inorganic Biochemistry, 2025, 262, 112740
DOI: 10.1016/j.jinorgbio.2024.112740

The binding mode of Ni-(L-His)2 in NikA revealed by X-ray crystallography

Hugo Lebrette, Marina Iannello, Juan C. Fontecilla-Camps and Christine Cavazza

Journal of Inorganic Biochemistry, 2013, 121, 16
DOI: 10.1016/j.jinorgbio.2012.12.010

In Vivo Assembly of a Genetically Encoded Artificial Metalloenzyme for Hydrogen Production

Kassandra J. Naughton, Regina E. Treviño, Peter J. Moore, Ashlee E. Wertz, J. Alex Dickson and Hannah S. Shafaat

ACS Synth. Biol., 2021, 10, 2116
DOI: 10.1021/acssynbio.1c00177

Uropathogenic enterobacteria use the yersiniabactin metallophore system to acquire nickel

Anne E. Robinson, Jessica E. Lowe, Eun-Ik Koh and Jeffrey P. Henderson

Journal of Biological Chemistry, 2018, 293, 14953
DOI: 10.1074/jbc.RA118.004483

Exploration into the nickel ‘microcosmos’ in prokaryotes

Tianfan Cheng, Hongyan Li, Wei Xia, Lijian Jin and Hongzhe Sun

Coordination Chemistry Reviews, 2016, 311, 24
DOI: 10.1016/j.ccr.2015.12.007

Periplasmic HupE region-Ni2+ interactions: Thermodynamics, binding mode and competition with Cu2+ and Zn2+

Magdalena Rowińska-Żyrek

Inorganica Chimica Acta, 2017, 460, 141
DOI: 10.1016/j.ica.2016.08.007

The requirement for cobalt in vitamin B12: A paradigm for protein metalation

Deenah Osman, Anastasia Cooke, Tessa R. Young, Evelyne Deery, Nigel J. Robinson and Martin J. Warren

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2021, 1868, 118896
DOI: 10.1016/j.bbamcr.2020.118896

Antihistamine drug loratadine at environmentally relevant concentrations promotes conjugative transfer of antibiotic resistance genes: Coeffect of oxidative stress and ion transport

Yong-Qiang Li, Chong-Miao Zhang and Yi Liu

Journal of Environmental Management, 2025, 376, 124430
DOI: 10.1016/j.jenvman.2025.124430

Metallophores and Trace Metal Biogeochemistry

Stephan M. Kraemer, Owen W. Duckworth, James M. Harrington and Walter D. C. Schenkeveld

Aquat Geochem, 2015, 21, 159
DOI: 10.1007/s10498-014-9246-7

Comparative genomic analysis of nickel homeostasis in cable bacteria

Anwar Hiralal, Jeanine S. Geelhoed, Sinje Neukirchen and Filip J. R. Meysman

BMC Genomics, 2024, 25
DOI: 10.1186/s12864-024-10594-7

Selective inhibition of NikA mediated Ni(II) import in E. coli by the Indium(III)-EDTA complex

Stephanie Sebastiampillai and Mark Nitz

Metallomics, 2025, 17
DOI: 10.1093/mtomcs/mfaf008

[NiFe]-Hydrogenase Maturation

Michael J. Lacasse and Deborah B. Zamble

Biochemistry, 2016, 55, 1689
DOI: 10.1021/acs.biochem.5b01328