Cross Reference Logo
Citations to this article as recorded by CrossRef and RSC Journals (370 citations).

Stimuli responsive synthetic polypeptides derived from N-carboxyanhydride (NCA) polymerisation
Jin Huang and Andreas Heise
Chem. Soc. Rev., 2013, 42, 7373
DOI: 10.1039/c3cs60063g

pH-Responsive protein nanoparticlesviaconjugation of degradable PEG to the surface of cytochromec
Elena Steiert, Johannes Ewald, Annika Wagner, Ute A. Hellmich, Holger Frey and Peter R. Wich
Polym. Chem., 2020, 11, 551
DOI: 10.1039/C9PY01162E

Poly(N-(2-hydroxypropyl) methacrylamide)-based nanotherapeutics
Bryan S. Tucker and Brent S. Sumerlin
Polym. Chem., 2014, 5, 1566
DOI: 10.1039/C3PY01279D

A controlled and versatile NCA polymerization method for the synthesis of polypeptides
Inmaculada Conejos-Sánchez, Aroa Duro-Castano, Alexander Birke, Matthias Barz and María J. Vicent
Polym. Chem., 2013, 4, 3182
DOI: 10.1039/c3py00347g

Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery
Liwang Shi, Jinqiu Zhang, Man Zhao, Shukun Tang, Xu Cheng, Wenyuan Zhang, Wenhua Li, Xiaoying Liu, Haisheng Peng and Qun Wang
Nanoscale, 2021, 13, 10748
DOI: 10.1039/D1NR02065J

Biocompatible cationic polypeptoids with antibacterial selectivity depending on hydrophobic carbon chain length
Xiran Shen, Yu Rao, Di Liu, Jinghong Wang, Xiaomeng Niu, Yichen Wang, Wentao Chen, Fan Liu, Li Guo and Hong Chen
J. Mater. Chem. B, 2023, 11, 5786
DOI: 10.1039/D3TB00643C

Ethyl acetate as solvent for the synthesis of poly(2-ethyl-2-oxazoline)
Maarten Vergaelen, Bart Verbraeken, Joachim F. R. Van Guyse, Annelore Podevyn, Ali Tigrine, Victor R. de la Rosa, Bryn D. Monnery and Richard Hoogenboom
Green Chem., 2020, 22, 1747
DOI: 10.1039/C9GC03872H

Continuous poly(2-oxazoline) triblock copolymer synthesis in a microfluidic reactor cascade
Evelien Baeten, Bart Verbraeken, Richard Hoogenboom and Tanja Junkers
Chem. Commun., 2015, 51, 11701
DOI: 10.1039/C5CC04319K

Crystallisation-driven self-assembly of poly(2-isopropyl-2-oxazoline)-block-poly(2-methyl-2-oxazoline) above the LCST
Camille Legros, Marie-Claire De Pauw-Gillet, Kam Chiu Tam, Daniel Taton and Sébastien Lecommandoux
Soft Matter, 2015, 11, 3354
DOI: 10.1039/C5SM00313J

Fast and accurate partial hydrolysis of poly(2-ethyl-2-oxazoline) into tailored linear polyethylenimine copolymers
Victor R. de la Rosa, Eva Bauwens, Bryn D. Monnery, Bruno G. De Geest and Richard Hoogenboom
Polym. Chem., 2014, 5, 4957
DOI: 10.1039/C4PY00355A

Facile synthesis of drug-conjugated PHPMA core-crosslinked star polymers
Bryan S. Tucker, Stephen G. Getchell, Megan R. Hill and Brent S. Sumerlin
Polym. Chem., 2015, 6, 4258
DOI: 10.1039/C5PY00497G

Comparison of the hydrophilicity of water-soluble poly(2-alkyl-2-oxazoline)s, poly(2-alkyl-2-oxazine)s and poly(2,4-dialkyl-2-oxazoline)s
Kelly Mint, Joshua P. Morrow, Nicole M. Warne, Xie He, David Pizzi, Shaffiq Zainal Osman Shah, Gregory K. Pierens, Nicholas L. Fletcher, Craig A. Bell, Kristofer J. Thurecht and Kristian Kempe
Polym. Chem., 2024, 15, 2662
DOI: 10.1039/D4PY00332B

Triblock architecture and PEG hydrophilic blocks enable efficient thermogelation of poly(2-phenyl-2-oxazine)-based worm-gels
Anna-Lena Ziegler, Andrew Kerr, Florian T. Kaps and Robert Luxenhofer
Polym. Chem., 2025, 16, 1383
DOI: 10.1039/D4PY01345J

A transdermal device from 2-hydroxyethyl methacrylate grafted carboxymethyl guar gum–multi-walled carbon nanotube composites
Arindam Giri, Tridib Bhunia, Samir R. Mishra, Luna Goswami, Asit B. Panda and Abhijit Bandyopadhyay
RSC Adv., 2014, 4, 13546
DOI: 10.1039/c3ra47511e

Polypeptoids with tunable cloud point temperatures synthesized from N-substituted glycine N-thiocarboxyanhydrides
Xinfeng Tao, Jianwei Du, Youxiang Wang and Jun Ling
Polym. Chem., 2015, 6, 3164
DOI: 10.1039/C5PY00191A

Recent developments in antimicrobial polymers for biofilm inhibition
Gillian A. Kropp, Cassell N. McMillian, Jonathan D. Mase, Sanjana Kandagiri, Elizabeth S. Nowak and Michael D. Schulz
Chem. Commun., 2026
DOI: 10.1039/D5CC06617D

Synthesis of architecturally well-defined nanogels via RAFT polymerization for potential bioapplications
Zesheng An, Qian Qiu and Guangyao Liu
Chem. Commun., 2011, 47, 12424
DOI: 10.1039/c1cc13955j

Cationic ring-opening polymerization of protected oxazolidine imines resulting in gradient copolymers of poly(2-oxazoline) and poly(urea)
Meike N. Leiske, Matthias Hartlieb, Fabian H. Sobotta, Renzo M. Paulus, Helmar Görls, Peter Bellstedt and Ulrich S. Schubert
Polym. Chem., 2016, 7, 4924
DOI: 10.1039/C6PY00785F

Colloidal hydroxyethyl starch for tumor-targeted platinum delivery
Chen Xiao, Hang Hu, Hai Yang, Si Li, Hui Zhou, Jian Ruan, Yuting Zhu, Xiangliang Yang and Zifu Li
Nanoscale Adv., 2019, 1, 1002
DOI: 10.1039/C8NA00271A

A versatile post-polymerization modification method for polyglutamic acid: synthesis of orthogonal reactive polyglutamates and their use in “click chemistry”
Matthias Barz, Aroa Duro-Castano and María J. Vicent
Polym. Chem., 2013, 4, 2989
DOI: 10.1039/c3py00189j

Functional nanoscale metal–organic particles synthesized from a new vinylimidazole-based polymeric ligand and dysprosium ions
Jian Cui, Guangfa Zhang, Lanxia Xin, Peng Yun, Yehai Yan and Feng Su
J. Mater. Chem. C, 2018, 6, 280
DOI: 10.1039/C7TC03795C

Controlled aggregation and cell uptake of thermoresponsive polyoxazoline-grafted superparamagnetic iron oxide nanoparticles
Steffen Kurzhals, Noga Gal, Ronald Zirbs and Erik Reimhult
Nanoscale, 2017, 9, 2793
DOI: 10.1039/C6NR08654C

Soft amphiphilic polyesters obtained from PEGs and silicon fatty compounds: structural characterizations and self-assembly studies
Daniela Andrade, Claudio Moya, Felipe Olate, Nicolás Gatica, Susana Sanchez, Enzo Díaz, Elizabeth Elgueta, María Parra and Mohamed Dahrouch
RSC Adv., 2016, 6, 38505
DOI: 10.1039/C6RA03725A

pH degradable dendron-functionalized poly(2-ethyl-2-oxazoline) prepared by a cascade “double-click” reaction
Kristian Kempe, Sebla Onbulak, Ulrich S. Schubert, Amitav Sanyal and Richard Hoogenboom
Polym. Chem., 2013, 4, 3236
DOI: 10.1039/c3py00258f

Photocleavable core cross-linked polymeric micelles of polypept(o)ides and ruthenium(ii) complexes
Tobias Alexander Bauer, Jonas Eckrich, Nadine Wiesmann, Felix Kuczelinis, Wen Sun, Xiaolong Zeng, Benjamin Weber, Si Wu, Nicolas Hubert Bings, Sebastian Strieth and Matthias Barz
J. Mater. Chem. B, 2021, 9, 8211
DOI: 10.1039/D1TB01336J

Polyoxazoline hydrogels fabricated by stereolithography
Thomas Brossier, Belkacem Tarek Benkhaled, Maxime Colpaert, Gael Volpi, Olivier Guillaume, Sébastien Blanquer and Vincent Lapinte
Biomater. Sci., 2022, 10, 2681
DOI: 10.1039/D2BM00138A

Polysarcosine functionalised cationic polyesters efficiently deliver self-amplifying mRNA
Hulya Bayraktutan, Rafał J. Kopiasz, Amr Elsherbeny, Magda Martinez Espuga, Nurcan Gumus, Umut Can Oz, Krunal Polra, Paul F. McKay, Robin J. Shattock, Paloma Ordóñez-Morán, Alvaro Mata, Cameron Alexander and Pratik Gurnani
Polym. Chem., 2024, 15, 1862
DOI: 10.1039/D4PY00064A

Antibiofouling polymer interfaces: poly(ethylene glycol) and other promising candidates
Sean Lowe, Neil M. O'Brien-Simpson and Luke A. Connal
Polym. Chem., 2015, 6, 198
DOI: 10.1039/C4PY01356E

Monodisperse polyethylene glycol “brushes” with enhanced lipophilicity, and thermo and plasma stability
Yu Li, Xuemeng Wang, Yongping Chen, Zhigang Yang and Zhong-Xing Jiang
Chem. Commun., 2019, 55, 1895
DOI: 10.1039/C8CC09151J

Facile synthesis of well-defined hydrophilic polyesters as degradable poly(ethylene glycol)-like biomaterials
Xiwen Li, Hua Li, Yongye Zhao, Xiaoying Tang, Sufang Ma, Bing Gong and Minfeng Li
Polym. Chem., 2015, 6, 6452
DOI: 10.1039/C5PY00762C

Unexpected radical polymerization behavior of oligo(2-ethyl-2-oxazoline) macromonomers
Christine Weber, Krzysztof Babiuch, Sarah Rogers, Igor Y. Perevyazko, Richard Hoogenboom and Ulrich S. Schubert
Polym. Chem., 2012, 3, 2976
DOI: 10.1039/c2py20479g

pH and redox responsive hydrogels and nanogels made from poly(2-ethyl-2-oxazoline)
Camille Legros, Marie-Claire De Pauw-Gillet, Kam Chiu Tam, Sébastien Lecommmandoux and Daniel Taton
Polym. Chem., 2013, 4, 4801
DOI: 10.1039/c3py00685a

Poly(2-oxazoline) molecular brushes by grafting through of poly(2-oxazoline)methacrylates with aqueous ATRP
Dan Gieseler and Rainer Jordan
Polym. Chem., 2015, 6, 4678
DOI: 10.1039/C5PY00561B

Smart branched polymer drug conjugates as nano-sized drug delivery systems
A. Duro-Castano, J. Movellan and M. J. Vicent
Biomater. Sci., 2015, 3, 1321
DOI: 10.1039/C5BM00166H

Amidation of methyl ester-functionalised poly(2-oxazoline)s as a powerful tool to create dual pH- and temperature-responsive polymers as potential drug delivery systems
Meike N. Leiske, Ronak Singha, Somdeb Jana, Bruno G. De Geest and Richard Hoogenboom
Polym. Chem., 2023, 14, 2034
DOI: 10.1039/D3PY00050H

Amphiphilic star-shaped poly(sarcosine)-block-poly(ε-caprolactone) diblock copolymers: one-pot synthesis, characterization, and solution properties
Saide Cui, Xianfu Pan, Hailemariam Gebru, Xin Wang, Jiaqi Liu, Jingjing Liu, Zhenjiang Li and Kai Guo
J. Mater. Chem. B, 2017, 5, 679
DOI: 10.1039/C6TB02145J

3D bioprinting tumor models mimic the tumor microenvironment for drug screening
Xuelian Mi, Zhi Su, Xiaokun Yue, Ya Ren, Xue Yang, Lei Qiang, Weiqing Kong, Zhenjiang Ma, Changru Zhang and Jinwu Wang
Biomater. Sci., 2023, 11, 3813
DOI: 10.1039/D3BM00159H

Indocyanine green-functionalized bottle brushes of poly(2-oxazoline) on cellulose nanocrystals for photothermal cancer therapy
Liman Hou, Jianyong Fang, Weiqi Wang, Zhigang Xie, Dewen Dong and Ning Zhang
J. Mater. Chem. B, 2017, 5, 3348
DOI: 10.1039/C7TB00812K

Engineered non-toxic cationic nanocarriers with photo-triggered slow-release properties
Ionel A. Dinu, Jason T. Duskey, Anja Car, Cornelia G. Palivan and Wolfgang Meier
Polym. Chem., 2016, 7, 3451
DOI: 10.1039/C6PY00343E

An amphiphilic graft copolymer-based nanoparticle platform for reduction-responsive anticancer and antimalarial drug delivery
Adrian Najer, Dalin Wu, Martin G. Nussbaumer, Geoffrey Schwertz, Anatol Schwab, Matthias C. Witschel, Anja Schäfer, François Diederich, Matthias Rottmann, Cornelia G. Palivan, Hans-Peter Beck and Wolfgang Meier
Nanoscale, 2016, 8, 14858
DOI: 10.1039/C6NR04290B

Synthesis and characterization of chitosan-coated titanate nanotubes: towards a new safe nanocarrier
Fadoua Sallem, Julien Boudon, Olivier Heintz, Isabelle Séverin, Adel Megriche and Nadine Millot
Dalton Trans., 2017, 46, 15386
DOI: 10.1039/C7DT03029K

Poly-ethylene glycol induced super-diffusivity in lipid bilayer membranes
Thibault Tabarin, Aaron Martin, Robert J. Forster and Tia E. Keyes
Soft Matter, 2012, 8, 8743
DOI: 10.1039/c2sm25742d

Deepening the insight into poly(butylene oxide)-block-poly(glycidol) synthesis and self-assemblies: micelles, worms and vesicles
Riccardo Wehr, Jens Gaitzsch, Davy Daubian, Csaba Fodor and Wolfgang Meier
RSC Adv., 2020, 10, 22701
DOI: 10.1039/D0RA04274A

In situ formed hybrid hydrogels from PEG based multifunctional hyperbranched copolymers: a RAFT approach
Robert Kennedy, Waqar Ul Hassan, Anna Tochwin, Tianyu Zhao, Yixiao Dong, Qiang Wang, Hongyun Tai and Wenxin Wang
Polym. Chem., 2014, 5, 1838
DOI: 10.1039/c3py01513k

Reactive oxygen species-sensitive thioether-bearing poly(2-oxazoline)s: direct and controlled polymerization using an initiator salt
Saba Nemati Mahand, Anna-Lena Ziegler, Parsa Amin, Florian T. Kaps and Robert Luxenhofer
Polym. Chem., 2025, 16, 4961
DOI: 10.1039/D5PY00659G

Aerosol delivery of biocompatible dihydroergotamine-loaded PLGA-PSPE polymeric micelles for efficient lung cancer therapy
Jian-Bin Qiao, Yoonjeong Jang, Qian-Qian Fan, Seung-Hee Chang, Lei Xing, Peng-Fei Cui, Yu-Jing He, Soomin Lee, Sunghyun Hwang, Myung-Haing Cho and Hu-Lin Jiang
Polym. Chem., 2017, 8, 1540
DOI: 10.1039/C7PY00024C

A block copolymer of zwitterionic polyphosphoester and polylactic acid for drug delivery
Rong Sun, Xiao-Jiao Du, Chun-Yang Sun, Song Shen, Yang Liu, Xian-Zhu Yang, Yan Bao, Yan-Hua Zhu and Jun Wang
Biomater. Sci., 2015, 3, 1105
DOI: 10.1039/C4BM00430B

One-step RAFT synthesis of well-defined amphiphilic star polymers and their self-assembly in aqueous solution
Christoph Herfurth, Paula Malo de Molina, Christoph Wieland, Sarah Rogers, Michael Gradzielski and André Laschewsky
Polym. Chem., 2012, 3, 1606
DOI: 10.1039/c2py20126g

Synthesis of peptide-grafted comb polypeptidesviapolymerisation of NCA-peptides
Hiroshi Enomoto, Benjamin Nottelet, Soultan Al Halifa, Christine Enjalbal, Mathieu Dupré, Julien Tailhades, Jean Coudane, Gilles Subra, Jean Martinez and Muriel Amblard
Chem. Commun., 2013, 49, 409
DOI: 10.1039/C2CC37597D

One-pot aqueous synthesis of sub-10 nm responsive nanogels
Luxian Li, Aiping Chang, Yumei Hu, Laiying Zhang and Weitai Wu
Chem. Commun., 2013, 49, 6534
DOI: 10.1039/c3cc41398e

Antifouling polymers for nanomedicine and surfaces: recent advances
Yi Jie Eng, Tuan Minh Nguyen, He-Kuan Luo and Julian M. W. Chan
Nanoscale, 2023, 15, 15472
DOI: 10.1039/D3NR03164K

Exploiting poly(α-hydroxy acids) for the acid-mediated release of doxorubicin and reversible inside–out nanoparticle self-assembly
Mthulisi Khuphe, Nicola Ingram and Paul D. Thornton
Nanoscale, 2018, 10, 14201
DOI: 10.1039/C8NR03897J

Three-arm star compounds composed of 1,3,5-tri(azobenzeneethynyl)benzene cores and flexible PEO arms: synthesis, optical functions, hybrid Ormosil gel glasses
Zheng Xie, Haifeng He, Yonghong Deng, Xiaogong Wang and Chunyan Liu
J. Mater. Chem. C, 2013, 1, 1791
DOI: 10.1039/c2tc00772j

Glucose-bearing biodegradable poly(amino acid) and poly(amino acid)-poly(ester) conjugates for controlled payload release
Mthulisi Khuphe, Clare S. Mahon and Paul D. Thornton
Biomater. Sci., 2016, 4, 1792
DOI: 10.1039/C6BM00535G

Methods of protein surface PEGylation under structure preservation for the emulsion-based formation of stable nanoparticles
Lydia Radi, Matthias Fach, Mirko Montigny, Elena Berger-Nicoletti, Wolfgang Tremel and Peter R. Wich
Med. Chem. Commun., 2016, 7, 1738
DOI: 10.1039/C5MD00475F

Polymeric micelles for ocular drug delivery: From structural frameworks to recent preclinical studies
Abhirup Mandal, Rohit Bisht, Ilva D. Rupenthal and Ashim K. Mitra
Journal of Controlled Release, 2017, 248, 96
DOI: 10.1016/j.jconrel.2017.01.012

Manipulation of protein corona for nanomedicines
Tao Li, Yupeng Wang and Dongfang Zhou
WIREs Nanomed Nanobiotechnol, 2024, 16
DOI: 10.1002/wnan.1982

Utility of Triethyloxonium Tetrafluoroborate for Chloride Removal during Sarcosine N‐Carboxyanhydride Synthesis: Improving NCA Purity
Leon Capelôa, Rafael Miravet Martí, Aroa Duro‐Castaño, Vicent J. Nebot and Matthias Barz
Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202304375

Optimizing the Cross‐Linking of Poly(2‐oxazoline)‐Based Hybrid Microgels for Cell Encapsulation via Radiation‐free Thiol‐Michael‐Addition Reaction
Sophia Loeffelsend, Chien‐Hsin Yu, Jeanette Weigelt, Stephan Hauschild, Joerg Tessmar, Stephan Foerster and Juergen Groll
Macromolecular Bioscience, 2026, 26
DOI: 10.1002/mabi.202500403

Proteins Conjugated with Sulfoxide-Containing Polymers Show Reduced Macrophage Cellular Uptake and Improved Pharmacokinetics
Ye Yu, Weizhi Xu, Xumin Huang, Xin Xu, Ruirui Qiao, Yuhuan Li, Felicity Han, Hui Peng, Thomas P. Davis, Changkui Fu and Andrew K. Whittaker
ACS Macro Lett., 2020, 9, 799
DOI: 10.1021/acsmacrolett.0c00291

PEGose Block Poly(lactic acid) Nanoparticles for Cargo Delivery
Jean-Baptiste Masclef, Emmanuelle M. N. Acs, Jesko Koehnke, Joëlle Prunet and Bernhard V. K. J. Schmidt
Macromolecules, 2024, 57, 6013
DOI: 10.1021/acs.macromol.4c00528

Influence of Riboflavin Targeting on Tumor Accumulation and Internalization of Peptostar Based Drug Delivery Systems
Milita Darguzyte, Regina Holm, Jasmin Baier, Natascha Drude, Jennifer Schultze, Kaloian Koynov, David Schwiertz, Seyed Mohammadali Dadfar, Twan Lammers, Matthias Barz and Fabian Kiessling
Bioconjugate Chem., 2020, 31, 2691
DOI: 10.1021/acs.bioconjchem.0c00593

Linear-Hyperbranched Graft-Copolymers via Grafting-to Strategy Based on Hyperbranched Dendron Analogues and Reactive Ester Polymers
Christoph Schüll, Lutz Nuhn, Christine Mangold, Eva Christ, Rudolf Zentel and Holger Frey
Macromolecules, 2012, 45, 5901
DOI: 10.1021/ma300972v

Recent advances and prospects in nano drug delivery systems using lipopolyoxazolines
L. Simon, N. Marcotte, J.M. Devoisselle, S. Begu and V. Lapinte
International Journal of Pharmaceutics, 2020, 585, 119536
DOI: 10.1016/j.ijpharm.2020.119536

Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability
Mirja Harms, Rikke Fabech Hansson, Sheiliza Carmali, Yasser Almeida-Hernández, Elsa Sanchez-Garcia, Jan Münch and Alexander N. Zelikin
Bioconjugate Chem., 2022, 33, 594
DOI: 10.1021/acs.bioconjchem.2c00034

Poly(S-ethylsulfonyl-l-homocysteine): An α-Helical Polypeptide for Chemoselective Disulfide Formation
Christian Muhl, Olga Schäfer, Tobias Bauer, Hans-Joachim Räder and Matthias Barz
Macromolecules, 2018, 51, 8188
DOI: 10.1021/acs.macromol.8b01442

Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications
Michaela Jeong, Yeji Lee, Jeongeun Park, Hyein Jung and Hyukjin Lee
Advanced Drug Delivery Reviews, 2023, 200, 114990
DOI: 10.1016/j.addr.2023.114990

Facile synthesis of AA'B- and ABC-type polypept(o)ide miktoarm star polymers utilizing polysarcosine end group functionalization for core introduction
Leon Capelôa, David Schwiertz and Matthias Barz
European Polymer Journal, 2023, 187, 111896
DOI: 10.1016/j.eurpolymj.2023.111896

Understanding Acid-Promoted Polymerization of the N-Substituted Glycine N-Thiocarboxyanhydride in Polar Solvents
Botuo Zheng, Songyi Xu, Xufeng Ni and Jun Ling
Biomacromolecules, 2021, 22, 1579
DOI: 10.1021/acs.biomac.1c00016

Main-Chain Phosphorus-Containing Polymers for Therapeutic Applications
Paul Strasser and Ian Teasdale
Molecules, 2020, 25, 1716
DOI: 10.3390/molecules25071716

Low dose novel PARP-PI3K inhibition via nanoformulation improves colorectal cancer immunoradiotherapy
M.R. Landry, A.N. DuRoss, M.J. Neufeld, L. Hahn, G. Sahay, R. Luxenhofer and C. Sun
Materials Today Bio, 2020, 8, 100082
DOI: 10.1016/j.mtbio.2020.100082

Structure-property relationship in cytotoxicity and cell uptake of poly(2-oxazoline) amphiphiles
Robert Luxenhofer, Gaurav Sahay, Anita Schulz, Daria Alakhova, Tatiana K. Bronich, Rainer Jordan and Alexander V. Kabanov
Journal of Controlled Release, 2011, 153, 73
DOI: 10.1016/j.jconrel.2011.04.010

Quo Vadis Nanomedicine?
Robert Luxenhofer, Matthias Barz and Michael Schillmeier
Nanomedicine (Lond.), 2014, 9, 2083
DOI: 10.2217/nnm.14.140

Polypeptide‐Based Conjugates as Therapeutics: Opportunities and Challenges
Oleksandr Zagorodko, Juan José Arroyo‐Crespo, Vicent J. Nebot and María J. Vicent
Macromolecular Bioscience, 2017, 17
DOI: 10.1002/mabi.201600316

Star‐shaped amphiphilic block polyurethane with pentaerythritol core for a hydrophobic drug delivery carrier
Shihai Wang, Yu Zhou, Bo Zhuang, Peng Zheng, Hongxiang Chen, Tongcun Zhang, Haiman Hu and Dengcheng Huang
Polymer International, 2016, 65, 551
DOI: 10.1002/pi.5092

Macromolecular Prodrugs for Controlled Delivery of Ribavirin
Mille B. L. Kryger, Anton A. A. Smith, Benjamin M. Wohl and Alexander N. Zelikin
Macromolecular Bioscience, 2014, 14, 173
DOI: 10.1002/mabi.201300244

Core-crosslinked polymeric micelles: Principles, preparation, biomedical applications and clinical translation
Marina Talelli, Matthias Barz, Cristianne J.F. Rijcken, Fabian Kiessling, Wim E. Hennink and Twan Lammers
Nano Today, 2015, 10, 93
DOI: 10.1016/j.nantod.2015.01.005

α-Amino acid N-thiocarboxyanhydrides: A novel synthetic approach toward poly(α-amino acid)s
Xinfeng Tao, Min-Hui Li and Jun Ling
European Polymer Journal, 2018, 109, 26
DOI: 10.1016/j.eurpolymj.2018.08.039

Structural and bioactive roles of fucoidan in nanogel delivery systems. A review
Ana Mayela Ramos-de-la-Peña, Juan Carlos Contreras-Esquivel, Oscar Aguilar and José González-Valdez
Carbohydrate Polymer Technologies and Applications, 2022, 4, 100235
DOI: 10.1016/j.carpta.2022.100235

Recent advances in nano/micro systems for improved circulation stability, enhanced tumor targeting, penetration, and intracellular drug delivery: a review
Wei-Jen Chan and Huatian Li
Biomed. Phys. Eng. Express, 2024, 10, 022001
DOI: 10.1088/2057-1976/ad14f0

Indium-based and iodine-based labeling of HPMA copolymer–epirubicin conjugates: Impact of structure on the in vivo fate
Libin Zhang, Rui Zhang, Jiyuan Yang, Jiawei Wang and Jindřich Kopeček
Journal of Controlled Release, 2016, 235, 306
DOI: 10.1016/j.jconrel.2016.06.004

Chemical Approaches to Synthetic Drug Delivery Systems for Systemic Applications
Daniel Braatz, Mariam Cherri, Michael Tully, Mathias Dimde, Guoxin Ma, Ehsan Mohammadifar, Felix Reisbeck, Vahid Ahmadi, Michael Schirner and Rainer Haag
Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202203942

The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy
Valentina Francia, Raymond M. Schiffelers, Pieter R. Cullis and Dominik Witzigmann
Bioconjugate Chem., 2020, 31, 2046
DOI: 10.1021/acs.bioconjchem.0c00366

DPPC:MPOx chimeric advanced Drug Delivery nano Systems (chi-aDDnSs): Physicochemical and structural characterization, stability and drug release studies
Natassa Pippa, Maria Merkouraki, Stergios Pispas and Costas Demetzos
International Journal of Pharmaceutics, 2013, 450, 1
DOI: 10.1016/j.ijpharm.2013.03.052

Partial Hydrolysis of Poly(2‐ethyl‐2‐oxazoline) and Potential Implications for Biomedical Applications?
Huub P. C. Van Kuringen, Joke Lenoir, Els Adriaens, Johan Bender, Bruno G. De Geest and Richard Hoogenboom
Macromolecular Bioscience, 2012, 12, 1114
DOI: 10.1002/mabi.201200080

Poly(2‐Hydroxymethyl‐2‐Oxazoline) as Super‐Hydrophilic Antifouling Polymer
Somdeb Jana, Milan Roels, Meike N. Leiske, Yann Bernhard, Bruno G. De Geest., Kristof Van Hecke and Richard Hoogenboom
Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202424873

Recent advances in macromolecular prodrugs
Camilla Frich Riber and Alexander N. Zelikin
Current Opinion in Colloid & Interface Science, 2017, 31, 1
DOI: 10.1016/j.cocis.2017.06.002

Coordinative Binding of Polymers to Metal–Organic Framework Nanoparticles for Control of Interactions at the Biointerface
Andreas Zimpel, Nader Al Danaf, Benjamin Steinborn, Jasmin Kuhn, Miriam Höhn, Tobias Bauer, Patrick Hirschle, Waldemar Schrimpf, Hanna Engelke, Ernst Wagner, Matthias Barz, Don C. Lamb, Ulrich Lächelt and Stefan Wuttke
ACS Nano, 2019, 13, 3884
DOI: 10.1021/acsnano.8b06287

Poly(Oxanorbornene)‐Protein Conjugates Prepared by Grafting‐to ROMP as Alternatives for PEG
Elizabathe Davis, Adam A. Caparco, Nicole F. Steinmetz and Jonathan K. Pokorski
Macromolecular Bioscience, 2024, 24
DOI: 10.1002/mabi.202300255

Amphiphilic diblock and triblock copolymers based on poly(2-methyl-2-oxazoline) and poly(D,L-lactide): Synthesis, physicochemical characterizations and self-assembly properties
Gaëlle Le Fer, Clémence Le Cœur, Jean-Michel Guigner, Catherine Amiel and Gisèle Volet
Polymer, 2019, 171, 149
DOI: 10.1016/j.polymer.2019.03.037

Self‐Assembly of Amphiphilic Block Copolypeptoids with C2‐C5 Side Chains in Aqueous Solution
Corinna Fetsch, Silvana Flecks, Dan Gieseler, Claudia Marschelke, Juliane Ulbricht, Karl‐Heinz van Pée and Robert Luxenhofer
Macro Chemistry & Physics, 2015, 216, 547
DOI: 10.1002/macp.201400534

In vivo comparative study of distinct polymeric architectures bearing a combination of paclitaxel and doxorubicin at a synergistic ratio
Hemda Baabur-Cohen, Laura Isabel Vossen, Harald Rune Krüger, Anat Eldar-boock, Eilam Yeini, Natalie Landa-Rouben, Galia Tiram, Stefanie Wedepohl, Ela Markovsky, Jonathan Leor, Marcelo Calderón and Ronit Satchi-Fainaro
Journal of Controlled Release, 2017, 257, 118
DOI: 10.1016/j.jconrel.2016.06.037

Poly-l-Lysine-Poly[HPMA] Block Copolymers Obtained by RAFT Polymerization as Polyplex-Transfection Reagents with Minimal Toxicity
Kristof Tappertzhofen, Franziska Weiser, Evelyn Montermann, Angelika Reske-Kunz, Matthias Bros and Rudolf Zentel
Macromol. Biosci., 2015, 15, 1159
DOI: 10.1002/mabi.201500022

Materials and methods for delivery of biological drugs
Alexander N. Zelikin, Carsten Ehrhardt and Anne Marie Healy
Nature Chem, 2016, 8, 997
DOI: 10.1038/nchem.2629

Targeting Cancer Chemotherapy Resistance by Precision Medicine-Driven Nanoparticle-Formulated Cisplatin
Svenja Siemer, Tobias A. Bauer, Paul Scholz, Christina Breder, Federico Fenaroli, Gregory Harms, Dimo Dietrich, Jörn Dietrich, Christine Rosenauer, Matthias Barz, Sven Becker, Sebastian Strieth, Christoph Reinhardt, Torsten Fauth, Jan Hagemann and Roland H. Stauber
ACS Nano, 2021, 15, 18541
DOI: 10.1021/acsnano.1c08632

Importance of Thermally Induced Aggregation on 19F Magnetic Resonance Imaging of Perfluoropolyether-Based Comb-Shaped Poly(2-oxazoline)s
Cheng Zhang, Ronny Javier Pibaque Sanchez, Changkui Fu, Ryan Clayden-Zabik, Hui Peng, Kristian Kempe and Andrew K. Whittaker
Biomacromolecules, 2019, 20, 365
DOI: 10.1021/acs.biomac.8b01549

Macromolecular prodrugs of ribavirin: Polymer backbone defines blood safety, drug release, and efficacy of anti-inflammatory effects
Kaja Zuwala, Camilla F. Riber, Kaja Borup Løvschall, Anna H.F. Andersen, Lise Sørensen, Paulina Gajda, Martin Tolstrup and Alexander N. Zelikin
Journal of Controlled Release, 2018, 275, 53
DOI: 10.1016/j.jconrel.2018.02.012

High MW polyethylene glycol prolongs circulation of pegloticase in mice with anti-PEG antibodies
Anne M. Talkington, Morgan D. McSweeney, Tao Zhang, Zibo Li, Andrew C. Nyborg, Brian LaMoreaux, Eric W. Livingston, Jonathan E. Frank, Hong Yuan and Samuel K. Lai
Journal of Controlled Release, 2021, 338, 804
DOI: 10.1016/j.jconrel.2021.08.051

Novel self-assembled micelles of amphiphilic poly(2-ethyl-2-oxazoline) -poly(L-lactide) diblock copolymers for sustained drug delivery
Feng Su, Peng Yun, Chenglong Li, Rongye Li, Laishun Xi, Yuandou Wang, Yangsheng Chen and Suming Li
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2019, 566, 120
DOI: 10.1016/j.colsurfa.2019.01.015

Hetero‐Diels‐Alder‐Cycloaddition mit RAFT‐Polymeren als Biokonjugationsplattform
Ana Beloqui, Shivshankar R. Mane, Marcel Langer, Mathias Glassner, Dennis M. Bauer, Ljiljana Fruk, Christopher Barner‐Kowollik and Guillaume Delaittre
Angewandte Chemie, 2020, 132, 20123
DOI: 10.1002/ange.202005747

Tailored Poly(2‐oxazoline) Polymer Brushes to Control Protein Adsorption and Cell Adhesion
Ning Zhang, Tilo Pompe, Ihsan Amin, Robert Luxenhofer, Carsten Werner and Rainer Jordan
Macromolecular Bioscience, 2012, 12, 926
DOI: 10.1002/mabi.201200026

Polyoxazolines for Nonfouling Surface Coatings — A Direct Comparison to the Gold Standard PEG
Rupert Konradi, Canet Acikgoz and Marcus Textor
Macromol. Rapid Commun., 2012, 33, 1663
DOI: 10.1002/marc.201200422

PeptoSomes for Vaccination: Combining Antigen and Adjuvant in Polypept(o)ide‐Based Polymersomes
Benjamin Weber, Cinja Kappel, Martin Scherer, Mark Helm, Matthias Bros, Stephan Grabbe and Matthias Barz
Macromolecular Bioscience, 2017, 17
DOI: 10.1002/mabi.201700061

Thermoresponsive Polypeptoid‐Coated Superparamagnetic Iron Oxide Nanoparticles by Surface‐Initiated Polymerization
Steffen Kurzhals, Barbara Pretzner, Erik Reimhult and Ronald Zirbs
Macro Chemistry & Physics, 2017, 218
DOI: 10.1002/macp.201700116

μPET imaging of the pharmacokinetic behavior of medium and high molar mass 89 Zr-labeled poly(2-ethyl-2-oxazoline) in comparison to poly(ethylene glycol)
Leonie wyffels, Thomas Verbrugghen, Bryn D. Monnery, Mathias Glassner, Sigrid Stroobants, Richard Hoogenboom and Steven Staelens
Journal of Controlled Release, 2016, 235, 63
DOI: 10.1016/j.jconrel.2016.05.048

The Protein Corona as a Confounding Variable of Nanoparticle-Mediated Targeted Vaccine Delivery
Matthias Bros, Lutz Nuhn, Johanna Simon, Lorna Moll, Volker Mailänder, Katharina Landfester and Stephan Grabbe
Front. Immunol., 2018, 9
DOI: 10.3389/fimmu.2018.01760

Combined polymer-curcumin conjugate and ependymal progenitor/stem cell treatment enhances spinal cord injury functional recovery
Raquel Requejo-Aguilar, Ana Alastrue-Agudo, Marta Cases-Villar, Eric Lopez-Mocholi, Richard England, María J. Vicent and Victoria Moreno-Manzano
Biomaterials, 2017, 113, 18
DOI: 10.1016/j.biomaterials.2016.10.032

The challenges facing block copolymer micelles for cancer therapy: In vivo barriers and clinical translation
Sina Eetezadi, Sandra N. Ekdawi and Christine Allen
Advanced Drug Delivery Reviews, 2015, 91, 7
DOI: 10.1016/j.addr.2014.10.001

Amphiphilic and segmented polyurethanes based on poly(ε-caprolactone)diol and poly(2-ethyl-2-oxazoline)diol: Synthesis, properties, and a preliminary performance study of the 3D printing
Leonardo Bueno Bronzeri, Cony Gauche, Leslie Gudimard, Edwin-Joffrey Courtial, Christophe Marquette and Maria Isabel Felisberti
European Polymer Journal, 2021, 151, 110449
DOI: 10.1016/j.eurpolymj.2021.110449

Microwave-assisted one-step synthesis of poly(2-isopropyl-2-oxazoline) block copolymers using a dual initiator for CROP and RAFT polymerization
Munhyung Kang, Minsang Cho, Sunyoo Kim and Ji Ho Youk
Fibers Polym, 2017, 18, 1215
DOI: 10.1007/s12221-017-7309-2

Poly(2‐oxazoline) block copolymer based formulations of taxanes: effect of copolymer and drug structure, concentration, and environmental factors
Youngee Seo, Anita Schulz, Yingchao Han, Zhijian He, Herdis Bludau, Xiaomeng Wan, Jing Tong, Tatiana K. Bronich, Marina Sokolsky, Robert Luxenhofer, Rainer Jordan and Alexander V. Kabanov
Polymers for Advanced Techs, 2015, 26, 837
DOI: 10.1002/pat.3556

Polysarcosine: The Best Alternative of Poly (Ethylene Glycol)
Manu Singhai and Sankha Bhattacharya
CAPS, 2021, 4, 93
DOI: 10.2174/2452271604999201124222313

UV-Induced Cationic Ring-Opening Polymerization of 2-Oxazolines for Hot Lithography
Nicolas Klikovits, Lisa Sinawehl, Patrick Knaack, Thomas Koch, Jürgen Stampfl, Christian Gorsche and Robert Liska
ACS Macro Lett., 2020, 9, 546
DOI: 10.1021/acsmacrolett.0c00055

Analysis of multi-drug cancer nanomedicine
Karina Benderski, Twan Lammers and Alexandros Marios Sofias
Nat. Nanotechnol., 2025, 20, 1163
DOI: 10.1038/s41565-025-01932-1

Peptoidosomes as nanoparticles from amphiphilic block alpha-peptoids using solid-phase-synthesis
J. Gaitzsch, K. Karu and G. Battaglia
European Polymer Journal, 2015, 73, 447
DOI: 10.1016/j.eurpolymj.2015.10.026

Poly(2-oxazoline) Hydrogels for Controlled Fibroblast Attachment
Brooke L. Farrugia, Kristian Kempe, Ulrich S. Schubert, Richard Hoogenboom and Tim R. Dargaville
Biomacromolecules, 2013, 14, 2724
DOI: 10.1021/bm400518h

Facile synthesis of amphiphilic AB3 and A3B miktoarm PeptoMiktoStars
David Schwiertz, Regina Holm and Matthias Barz
Polym J, 2020, 52, 119
DOI: 10.1038/s41428-019-0269-1

Synthesis and Sequential Deprotection of Triblock Copolypept(o)ides Using Orthogonal Protective Group Chemistry
Philipp Heller, Benjamin Weber, Alexander Birke and Matthias Barz
Macromol. Rapid Commun., 2015, 36, 38
DOI: 10.1002/marc.201400466

One‐Pot Glovebox‐Free Synthesis, Characterization, and Self‐Assembly of Novel Amphiphilic Poly(Sarcosine‐b‐Caprolactone) Diblock Copolymers
Saide Cui, Xin Wang, Zhenjiang Li, Qiguo Zhang, Wenzhuo Wu, Jingjing Liu, Hao Wu, Cheng Chen and Kai Guo
Macromol. Rapid Commun., 2014, 35, 1954
DOI: 10.1002/marc.201400348

Increased the TMZ concentration in brain by poly(2-ethyl-2-oxazoline) conjugated temozolomide prodrug micelles for glioblastoma treatment
Kang Xu, Long Zhang, Yuqi Gu, Huasha Yang, Baixiang Du, Hongmei Liu and Yuling Li
European Polymer Journal, 2021, 145, 110232
DOI: 10.1016/j.eurpolymj.2020.110232

Are N‐substituted glycine N‐thiocarboxyanhydride monomers really hard to polymerize?
Xinfeng Tao, Botuo Zheng, Hans R. Kricheldorf and Jun Ling
J. Polym. Sci. Part A: Polym. Chem., 2017, 55, 404
DOI: 10.1002/pola.28402

Pyridyl Disulfide Functionalized Polymers as Nanotherapeutic Platforms
Binglin Sui, Chen Cheng and Peisheng Xu
Advanced Therapeutics, 2019, 2
DOI: 10.1002/adtp.201900062

From LC‐polymers to Nanomedicines: Different Aspects of Polymer Science from a Materials Viewpoint
Rudolf Zentel
Macro Chemistry & Physics, 2019, 220
DOI: 10.1002/macp.201900448

Toward Quantitative End-Group Fidelity in the Synthesis of High Molecular Weight Polysarcosine
Zlata Nagorna, Matthias Barz and Joachim F. R. Van Guyse
ACS Macro Lett., 2025, 14, 532
DOI: 10.1021/acsmacrolett.5c00165

Efficient Synthesis of Macromolecular DO3A@Gn Derivatives for Potential Application in MRI Diagnostics: From Polymer Conjugates to Polymer Nanoparticles
Anne‐Larissa Kampmann, Wolf Hiller and Ralf Weberskirch
Macro Chemistry & Physics, 2023, 224
DOI: 10.1002/macp.202200211

Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs
Sean A. Dilliard and Daniel J. Siegwart
Nat Rev Mater, 2023, 8, 282
DOI: 10.1038/s41578-022-00529-7

Challenges and Opportunities in the Delivery of Cancer Therapeutics: Update on Recent Progress
Mathilde Lorscheider, Alice Gaudin, Jessica Nakhlé, Kadi-Liis Veiman, Joël Richard and Christophe Chassaing
Ther. Deliv., 2021, 12, 55
DOI: 10.4155/tde-2020-0079

Liposomal Templating, Association with Mammalian Cells, and Cytotoxicity of Poly(vinyl alcohol) Physical Hydrogel Nanoparticles
Sidsel Ø. Andreasen, Siow‐Feng Chong, Mille B. L. Kryger, Bettina E. B. Jensen, Almar Postma, Marie‐Helene Alves, Brigitte Städler, Kenneth N. Goldie and Alexander N. Zelikin
Part & Part Syst Charact, 2013, 30, 514
DOI: 10.1002/ppsc.201200134

Poly-l-glutamic acid modification modulates the bio-nano interface of a therapeutic anti-IGF-1R antibody in prostate cancer
Sonia Vicente-Ruiz, Ana Armiñán, Katia Maso, Elena Gallon, Oleksandr Zagorodko, Julie Movellan, Fernanda Rodríguez-Otormín, Maike Baues, Jan-Niklas May, Federica De Lorenzi, Twan Lammers and María J. Vicent
Biomaterials, 2023, 301, 122280
DOI: 10.1016/j.biomaterials.2023.122280

Synthesis of tetraarm star block copolymer based on polytetrahydrofuran and poly(2-methyl-2-oxazoline) for gene delivery applications
Bazoly Rasolonjatovo, Bruno Pitard, Thomas Haudebourg, Véronique Bennevault and Philippe Guégan
European Polymer Journal, 2017, 88, 689
DOI: 10.1016/j.eurpolymj.2016.09.042

Glucose-Containing Diblock Polycations Exhibit Molecular Weight, Charge, and Cell-Type Dependence for pDNA Delivery
Yaoying Wu, Miao Wang, Dustin Sprouse, Adam E. Smith and Theresa M. Reineke
Biomacromolecules, 2014, 15, 1716
DOI: 10.1021/bm5001229

DPPC/poly(2-methyl-2-oxazoline)-grad-poly(2-phenyl-2-oxazoline) chimeric nanostructures as potential drug nanocarriers
Natassa Pippa, Eleni Kaditi, Stergios Pispas and Costas Demetzos
J Nanopart Res, 2013, 15
DOI: 10.1007/s11051-013-1685-3

Self-Assembly and Enzyme Responsiveness of Amphiphilic Linear-Dendritic Block Copolymers Based on Poly(N-vinylpyrrolidone) and Dendritic Phenylalanyl-lysine Dipeptides
Junwu Wei, Feng Lin, Dan You, Yangyang Qian, Yujia Wang and Yunmei Bi
Polymers, 2019, 11, 1625
DOI: 10.3390/polym11101625

The effects of protein corona on in vivo fate of nanocarriers
Qingqing Xiao, Makhloufi Zoulikha, Min Qiu, Chao Teng, Chenshi Lin, Xiaotong Li, Marwa A. Sallam, Qiaobing Xu and Wei He
Advanced Drug Delivery Reviews, 2022, 186, 114356
DOI: 10.1016/j.addr.2022.114356

Polymeric delivery systems for nucleic acid therapeutics: Approaching the clinic
Annette I.S. van den Berg, Chae-Ok Yun, Raymond M. Schiffelers and Wim E. Hennink
Journal of Controlled Release, 2021, 331, 121
DOI: 10.1016/j.jconrel.2021.01.014

Extended blood circulation and joint accumulation of a p(HPMA-co-AzMA)-based nanoconjugate in a murine model of rheumatoid arthritis
Morten F Ebbesen, Konrad Bienk, Bent W Deleuran and Kenneth A Howard
Mol and Cell Ther, 2014, 2, 29
DOI: 10.1186/2052-8426-2-29

Nanoparticle-macrophage interactions: A balance between clearance and cell-specific targeting
Rahul Rattan, Somnath Bhattacharjee, Hong Zong, Corban Swain, Muneeb A. Siddiqui, Scott H. Visovatti, Yogendra Kanthi, Sajani Desai, David J. Pinsky and Sascha N. Goonewardena
Bioorganic & Medicinal Chemistry, 2017, 25, 4487
DOI: 10.1016/j.bmc.2017.06.040

Combining Ring-Opening Multibranching and RAFT Polymerization: Multifunctional Linear–Hyperbranched Block Copolymers via Hyperbranched Macro-Chain-Transfer Agents
Lutz Nuhn, Christoph Schüll, Holger Frey and Rudolf Zentel
Macromolecules, 2013, 46, 2892
DOI: 10.1021/ma4002897

Silk Bioconjugates: From Chemistry and Concept to Application
Saphia A. L. Matthew and F. Philipp Seib
ACS Biomater. Sci. Eng., 2024, 10, 12
DOI: 10.1021/acsbiomaterials.2c01116

Cooperative Catechol-Functionalized Polypept(o)ide Brushes and Ag Nanoparticles for Combination of Protein Resistance and Antimicrobial Activity on Metal Oxide Surfaces
Jin Yoo, Alexander Birke, Joonwon Kim, Yeongseon Jang, Seuk Young Song, Seungmi Ryu, Byung-Soo Kim, Byung-Gee Kim, Matthias Barz and Kookheon Char
Biomacromolecules, 2018, 19, 1602
DOI: 10.1021/acs.biomac.8b00135

Polyglycerol Surfmers and Surfactants for Direct and Inverse Miniemulsion
Sarah Wald, Johanna Simon, Jule P. Dietz, Frederik R. Wurm and Katharina Landfester
Macromolecular Bioscience, 2017, 17
DOI: 10.1002/mabi.201700070

Size-Shifting Micelle Nanoclusters Based on a Cross-Linked and pH-Sensitive Framework for Enhanced Tumor Targeting and Deep Penetration Features
Huihui Liang, Xiaoqing Ren, Jianghui Qian, Xiulei Zhang, Lin Meng, Xiaofei Wang, Lei Li, Xiaoling Fang and Xianyi Sha
ACS Appl. Mater. Interfaces, 2016, 8, 10136
DOI: 10.1021/acsami.6b00668

The chemistry of poly(2-oxazoline)s
Bart Verbraeken, Bryn D. Monnery, Kathleen Lava and Richard Hoogenboom
European Polymer Journal, 2017, 88, 451
DOI: 10.1016/j.eurpolymj.2016.11.016

Conjugates of Superoxide Dismutase 1 with Amphiphilic Poly(2-oxazoline) Block Copolymers for Enhanced Brain Delivery: Synthesis, Characterization and Evaluation in Vitro and in Vivo
Jing Tong, Xiang Yi, Robert Luxenhofer, William A. Banks, Rainer Jordan, Matthew C. Zimmerman and Alexander V. Kabanov
Mol. Pharmaceutics, 2013, 10, 360
DOI: 10.1021/mp300496x

Polymer therapeutics as nanomedicines: new perspectives
Ruth Duncan
Current Opinion in Biotechnology, 2011, 22, 492
DOI: 10.1016/j.copbio.2011.05.507

Poly(ε-caprolactone)-block-polysarcosine by Ring-Opening Polymerization of Sarcosine N-Thiocarboxyanhydride: Synthesis and Thermoresponsive Self-Assembly
Yangwei Deng, Tao Zou, Xinfeng Tao, Vincent Semetey, Sylvain Trepout, Sergio Marco, Jun Ling and Min-Hui Li
Biomacromolecules, 2015, 16, 3265
DOI: 10.1021/acs.biomac.5b00930

Progress and Challenges in PEGylated Proteins Downstream Processing: A Review of the Last 8 Years
Ana Mayela Ramos-de-la-Peña and Oscar Aguilar
Int J Pept Res Ther, 2020, 26, 333
DOI: 10.1007/s10989-019-09840-4

Mitigating the Effects of Persistent Antipolymer Immune Reactions in Nanomedicine: Evaluating Materials-Based Approaches Using Molecular Imaging
James Humphries, Nicholas L. Fletcher, Stefan E. Sonderegger, Craig A. Bell, Kristian Kempe and Kristofer J. Thurecht
ACS Nano, 2024
DOI: 10.1021/acsnano.4c07317

Linking two worlds in polymer chemistry: The influence of block uniformity and dispersity in amphiphilic block copolypeptoids on their self‐assembly
Niklas Gangloff, Marcel Höferth, Vladimir Stepanenko, Benedikt Sochor, Bernhard Schummer, Joachim Nickel, Heike Walles, Randolf Hanke, Frank Würthner, Ronald N. Zuckermann and Robert Luxenhofer
Biopolymers, 2019, 110
DOI: 10.1002/bip.23259

Synthesis and Evaluation of Boronated 4‐Arm Polyethylene Glycol for Application in Transmucosal Drug Delivery
Oluwadamilola Miriam Kolawole, Tolulope Mathew Agbelusi and Prasopchai Patrojanasophon
ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202304781

Hydrogen Bonded Multilayer Films Based on Poly(2‐oxazoline)s and Tannic Acid
Anandhakumar Sundaramurthy, Maarten Vergaelen, Samarendra Maji, Rachel Auzély‐Velty, Zhiyue Zhang, Bruno G. De Geest and Richard Hoogenboom
Adv Healthcare Materials, 2014, 3, 2040
DOI: 10.1002/adhm.201400377

A New Way to Silicone‐Based Peptide Polymers
Said Jebors, Jeremie Ciccione, Soultan Al‐Halifa, Benjamin Nottelet, Christine Enjalbal, Céline M'Kadmi, Muriel Amblard, Ahmad Mehdi, Jean Martinez and Gilles Subra
Angew Chem Int Ed, 2015, 54, 3778
DOI: 10.1002/anie.201411065

Demonstrating the importance of polymer-conjugate conformation in solution on its therapeutic output: Diethylstilbestrol (DES)-polyacetals as prostate cancer treatment
Vanessa Giménez, Craig James, Ana Armiñán, Ralf Schweins, Alison Paul and María J. Vicent
Journal of Controlled Release, 2012, 159, 290
DOI: 10.1016/j.jconrel.2011.12.035

Engineering a Nano/Biointerface for Cell and Organ-Selective Drug Delivery
Donghui Song and Qiaobing Xu
Langmuir, 2022, 38, 9092
DOI: 10.1021/acs.langmuir.2c01609

Living Radical Polymerization by the RAFT Process – A Third Update
Graeme Moad, Ezio Rizzardo and San H. Thang
Australian Journal of Chemistry, 2012, 65, 985
DOI: 10.1071/CH12295

Polyoxazolines with a Vicinally Double-Bioactivated Terminus for Biomacromolecular Affinity Assessment
Florian Pinzner, Thorsten Keller, Jürgen Mut, Julian Bechold, Jürgen Seibel and Jürgen Groll
Sensors, 2021, 21, 3153
DOI: 10.3390/s21093153

Block Copolymer Micelles in Nanomedicine Applications
Horacio Cabral, Kanjiro Miyata, Kensuke Osada and Kazunori Kataoka
Chem. Rev., 2018, 118, 6844
DOI: 10.1021/acs.chemrev.8b00199

Supramolecular Linear-g-Hyperbranched Graft Polymers: Topology and Binding Strength of Hyperbranched Side Chains
Christian Moers, Lutz Nuhn, Marcel Wissel, René Stangenberg, Mihail Mondeshki, Elena Berger-Nicoletti, Anja Thomas, David Schaeffel, Kaloian Koynov, Markus Klapper, Rudolf Zentel and Holger Frey
Macromolecules, 2013, 46, 9544
DOI: 10.1021/ma402081h

Bridging Frontiers in Macromolecular and Supramolecular Sciences with Living Cationic Ring‐Opening Polymerization of Self‐Organizable Dendronized Cyclic‐Imino Ethers Generating Soft Frank–Kasper and Quasicrystal Arrays
Virgil Percec and Dipankar Sahoo
Macro Chemistry & Physics, 2025, 226
DOI: 10.1002/macp.202400339

Catechol End-Functionalized Polysarcosine for Insitu Synthesis and Stabilization of Silver Nanoparticles
Hailemariam Gebru and Zhenjiang Li
MRS Advances, 2020, 5, 1113
DOI: 10.1557/adv.2020.141

Cisplatin‐Rich Polyoxazoline–Poly(aspartic acid) Supramolecular Nanoparticles
Peng Zhang, Kangjun Yuan, Cheng Li, Xiaoke Zhang, Wei Wu and Xiqun Jiang
Macromolecular Bioscience, 2017, 17
DOI: 10.1002/mabi.201700206

Metabolically Active, Fully Hydrolysable Polymersomes
Yunqing Zhu, Alessandro Poma, Loris Rizzello, Virginia M. Gouveia, Lorena Ruiz‐Perez, Giuseppe Battaglia and Charlotte K. Williams
Angewandte Chemie, 2019, 131, 4629
DOI: 10.1002/ange.201814320

Polypeptoids from N-Substituted Glycine N-Carboxyanhydrides: Hydrophilic, Hydrophobic, and Amphiphilic Polymers with Poisson Distribution
Corinna Fetsch, Arlett Grossmann, Lisa Holz, Jonas F. Nawroth and Robert Luxenhofer
Macromolecules, 2011, 44, 6746
DOI: 10.1021/ma201015y

Drug Delivery Systems Based on Poly(2‐Oxazoline)s and Poly(2‐Oxazine)s
Ondrej Sedlacek and Richard Hoogenboom
Advanced Therapeutics, 2020, 3
DOI: 10.1002/adtp.201900168

How to Modulate the Chemical Structure of Polyoxazolines by Appropriate Functionalization
Brieuc Guillerm, Sophie Monge, Vincent Lapinte and Jean‐Jacques Robin
Macromol. Rapid Commun., 2012, 33, 1600
DOI: 10.1002/marc.201200266

Considering the immunogenicity of PEG: strategies for overcoming issues with PEGylated nanomedicines
Kouichi Shiraishi
Nanomedicine, 2025, 20, 2375
DOI: 10.1080/17435889.2025.2538423

Poly(glutamic acid): From natto to drug delivery systems
Leah C. Johnson, Adekunle Titus Akinmola and Carmen Scholz
Biocatalysis and Agricultural Biotechnology, 2022, 40, 102292
DOI: 10.1016/j.bcab.2022.102292

Development and optimization of solid lipid nanoparticles coated with chitosan and poly(2-ethyl-2-oxazoline) for ocular drug delivery of ciprofloxacin
Adaeze L. Onugwu, Anthony A. Attama, Petra O. Nnamani, Sabastine O. Onugwu, Ebele B. Onuigbo and Vitaliy V. Khutoryanskiy
Journal of Drug Delivery Science and Technology, 2022, 74, 103527
DOI: 10.1016/j.jddst.2022.103527

PEGylated Silk Fibroin Nanoparticles for Oral Antibiotic Delivery: Insights into Drug–Carrier Interactions and Process Greenness
Duy Toan Pham, Thi Truc Dao Le, Ngoc Yen Nguyen, Chong Kim Thien Duc, Nguyen Trong Tuan, Huynh Vu Thanh Luong, Quyen Thi Bich Tran, Manh Quan Nguyen and Bui Thi Phuong Thuy
ACS Omega, 2025, 10, 11627
DOI: 10.1021/acsomega.5c01089

Metabolically Active, Fully Hydrolysable Polymersomes
Yunqing Zhu, Alessandro Poma, Loris Rizzello, Virginia M. Gouveia, Lorena Ruiz‐Perez, Giuseppe Battaglia and Charlotte K. Williams
Angew Chem Int Ed, 2019, 58, 4581
DOI: 10.1002/anie.201814320

Polysarcosine-Based Lipids: From Lipopolypeptoid Micelles to Stealth-Like Lipids in Langmuir Blodgett Monolayers
Benjamin Weber, Christine Seidl, David Schwiertz, Martin Scherer, Stefan Bleher, Regine Süss and Matthias Barz
Polymers, 2016, 8, 427
DOI: 10.3390/polym8120427

Influence of anchoring segments on methacrylate-based comb-type hydrophilic polymer segments coated on silica surfaces using the grafting-to method
Shigehito Osawa, Masato Kashiwakura, Hiro Yamaguchi and Hidenori Otsuka
Colloid and Interface Science Communications, 2020, 36, 100258
DOI: 10.1016/j.colcom.2020.100258

Poly(2-oxazoline)s and click chemistry: A versatile toolbox toward multi-functional polymers
Kathleen Lava, Bart Verbraeken and Richard Hoogenboom
European Polymer Journal, 2015, 65, 98
DOI: 10.1016/j.eurpolymj.2015.01.014

Chiral and water‐soluble poly(2‐oxazoline)s
Robert Luxenhofer, Stephan Huber, Julia Hytry, Jing Tong, Alexander V. Kabanov and Rainer Jordan
J. Polym. Sci. A Polym. Chem., 2013, 51, 732
DOI: 10.1002/pola.26437

Synthesis and self-assembly of AB2-type amphiphilic copolymers from biobased hydroxypropyl methyl cellulose and poly(L-lactide)
Aijing Lu, Jielin Wang, Marleny Caceres Najarro, Suming Li and Andre Deratani
Carbohydrate Polymers, 2019, 211, 133
DOI: 10.1016/j.carbpol.2019.01.110

(Bio)degradable and Biocompatible Nano-Objects from Polymerization-Induced and Crystallization-Driven Self-Assembly
Chen Zhu and Julien Nicolas
Biomacromolecules, 2022, 23, 3043
DOI: 10.1021/acs.biomac.2c00230

HPMA Copolymers as Surfactants in the Preparation of Biocompatible Nanoparticles for Biomedical Application
Annette Kelsch, Stephanie Tomcin, Kristin Rausch, Matthias Barz, Volker Mailänder, Manfred Schmidt, Katharina Landfester and Rudolf Zentel
Biomacromolecules, 2012, 13, 4179
DOI: 10.1021/bm301453g

Poly(2‐oxazoline)s as Polymer Therapeutics
Robert Luxenhofer, Yingchao Han, Anita Schulz, Jing Tong, Zhijian He, Alexander V. Kabanov and Rainer Jordan
Macromol. Rapid Commun., 2012, 33, 1613
DOI: 10.1002/marc.201200354

Toward Protein-Repellent Surface Coatings from Catechol-Containing Cationic Poly(2-ethyl-2-oxazoline)
Nils Lüdecke, Marek Bekir, Stephan Eickelmann, Matthias Hartlieb and Helmut Schlaad
ACS Appl. Mater. Interfaces, 2023, 15, 19582
DOI: 10.1021/acsami.2c22518

Polymer therapeutics-prospects for 21st century: The end of the beginning
Ruth Duncan and María J. Vicent
Advanced Drug Delivery Reviews, 2013, 65, 60
DOI: 10.1016/j.addr.2012.08.012

Alendronate-Functionalized Poly(2-oxazoline)s with Tunable Affinity for Calcium Cations
María J. Sánchez-Fernández, Mikey R. Immers, Rosa P. Félix Lanao, Fang Yang, Johan C. M. E. Bender, Jasmin Mecinović, Sander C. G. Leeuwenburgh and Jan C. M. van Hest
Biomacromolecules, 2019, 20, 2913
DOI: 10.1021/acs.biomac.9b00104

Detailed characterization of poly(2‐ethyl‐2oxazoline)s by energy variable collision‐induced dissociation study
Esra Altuntas, Christine Weber and Ulrich S. Schubert
Rapid Comm Mass Spectrometry, 2013, 27, 1095
DOI: 10.1002/rcm.6542

Molecular weight distribution and endgroup functionality of poly(2-ethyl-2-oxazoline) prepolymers
O. Celebi, S.R. Barnes, G.S. Narang, D. Kellogg, S.J. Mecham and J.S. Riffle
Polymer, 2015, 56, 147
DOI: 10.1016/j.polymer.2014.11.005

Near-infrared activatable phthalocyanine-poly-L-glutamic acid conjugate: increased cellular uptake and light–dark toxicity ratio toward an effective photodynamic cancer therapy
Lik Voon Kiew, Hoay Yan Cheah, Siew Hui Voon, Elena Gallon, Julie Movellan, Kia Hui Ng, Serkan Alpugan, Hong Boon Lee, Fabienne Dumoulin, María J. Vicent and Lip Yong Chung
Nanomedicine: Nanotechnology, Biology and Medicine, 2017, 13, 1447
DOI: 10.1016/j.nano.2017.02.002

Green Capping Agents and Digestive Ripening for Size Control of Magnetite for Magnetic Fluid Hyperthermia
Heba Kahil, Ismail Abd El-Rahim Ali and Hadir Ebraheem
CNM, 2024, 9, 239
DOI: 10.2174/2405461508666230606124615

Synthesis of Heterotelechelic Poly(N‐ethylglycine) Polymers: from Polypeptoid Lipid Conjugates to Protein‐Polymer Conjugates
Ewout Buijs, Zlata Nagorna, Joachim F. R. Van Guyse and Matthias Barz
Macromol. Rapid Commun., 2025, 46
DOI: 10.1002/marc.202500422

Glucose-Functionalized, Serum-Stable Polymeric Micelles from the Combination of Anionic and RAFT Polymerizations
Ligeng Yin, Molly C. Dalsin, Antons Sizovs, Theresa M. Reineke and Marc A. Hillmyer
Macromolecules, 2012, 45, 4322
DOI: 10.1021/ma300218n

Poly(2‐oxazoline) Hydrogels: State‐of‐the‐Art and Emerging Applications
Tim R. Dargaville, Jong‐Ryul Park and Richard Hoogenboom
Macromolecular Bioscience, 2018, 18
DOI: 10.1002/mabi.201800070

An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications
Matthias Kuhlmann, Jonas B.R. Hamming, Anders Voldum, Georgia Tsakiridou, Maja T. Larsen, Julie S. Schmøkel, Emil Sohn, Konrad Bienk, David Schaffert, Esben S. Sørensen, Jesper Wengel, Daniel M. Dupont and Kenneth A. Howard
Molecular Therapy - Nucleic Acids, 2017, 9, 284
DOI: 10.1016/j.omtn.2017.10.004

Facile Generation of Heterotelechelic Poly(2‐Oxazoline)s Towards Accelerated Exploration of Poly(2‐Oxazoline)‐Based Nanomedicine
Joachim F. R. Van Guyse, Saed Abbasi, Kazuko Toh, Zlata Nagorna, Junjie Li, Anjaneyulu Dirisala, Sabina Quader, Satoshi Uchida and Kazunori Kataoka
Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202404972

Polysarcosine-containing copolymers: Synthesis, characterization, self-assembly, and applications
Alexander Birke, Jun Ling and Matthias Barz
Progress in Polymer Science, 2018, 81, 163
DOI: 10.1016/j.progpolymsci.2018.01.002

Direct Photomodification of Polymer Surfaces: Unleashing the Potential of Aryl‐Azide Copolymers
Anita Schulz, Antonio Stocco, Audrey Bethry, Jean‐Philippe Lavigne, Jean Coudane and Benjamin Nottelet
Adv Funct Materials, 2018, 28
DOI: 10.1002/adfm.201800976

Evaluating the impact of chaotropic salts on protein corona formation on polyethylene glycol-b-polylactic acid polymersomes
Owen Tabah, Daniel Nichols, Ashley Blake, Grace Witt, Chau-wen Chou and Jessica Larsen
Journal of Colloid and Interface Science, 2025, 699, 138195
DOI: 10.1016/j.jcis.2025.138195

Functionalization of Active Ester-Based Polymersomes for Enhanced Cell Uptake and Stimuli-Responsive Cargo Release
Martin Scherer, Cinja Kappel, Nicole Mohr, Karl Fischer, Philipp Heller, Romina Forst, Frank Depoix, Matthias Bros and Rudolf Zentel
Biomacromolecules, 2016, 17, 3305
DOI: 10.1021/acs.biomac.6b01049

Patterned Polypeptoid Brushes
Maximilian Schneider, Zian Tang, Marcus Richter, Claudia Marschelke, Paul Förster, Erik Wegener, Ihsan Amin, Heike Zimmermann, Dieter Scharnweber, Hans‐Georg Braun, Robert Luxenhofer and Rainer Jordan
Macromolecular Bioscience, 2016, 16, 75
DOI: 10.1002/mabi.201500314

Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery
Piotr S. Kowalski, Arnab Rudra, Lei Miao and Daniel G. Anderson
Molecular Therapy, 2019, 27, 710
DOI: 10.1016/j.ymthe.2019.02.012

Towards development of biobetter: L-asparaginase a case study
Rajan K. Tripathy, J. Anakha and Abhay H. Pande
Biochimica et Biophysica Acta (BBA) - General Subjects, 2024, 1868, 130499
DOI: 10.1016/j.bbagen.2023.130499

Poly(2-Hydroxyethyl Methacrylate)-b-Poly(L-Lysine) Cationic Hybrid Materials for Non-Viral Gene Delivery in NIH 3T3 Mouse Embryonic Fibroblasts
Renjith P. Johnson, Saji Uthaman, Johnson V. John, Min Seon Heo, In Kyu Park, Hongsuk Suh and Il Kim
Macromol. Biosci., 2014, 14, 1239
DOI: 10.1002/mabi.201400071

Impact of Polymer Bioconjugation on Protein Stability and Activity Investigated with Discrete Conjugates: Alternatives to PEGylation
Josefine Morgenstern, Gabriela Gil Alvaradejo, Nicolai Bluthardt, Ana Beloqui, Guillaume Delaittre and Jürgen Hubbuch
Biomacromolecules, 2018, 19, 4250
DOI: 10.1021/acs.biomac.8b01020

One to one comparison of cell-free synthesized erythropoietin conjugates modified with linear polyglycerol and polyethylene glycol
Paria Pouyan, Anne Zemella, Jeffrey L. Schloßhauer, Ruben M. Walter, Rainer Haag and Stefan Kubick
Sci Rep, 2023, 13
DOI: 10.1038/s41598-023-33463-x

Studying the colloidal behavior of chimeric liposomes by cryo-TEM, micro-differential scanning calorimetry and high-resolution ultrasound spectroscopy
Natassa Pippa, Diego Romano Perinelli, Stergios Pispas, Giulia Bonacucina, Costas Demetzos, Aleksander Forys and Barbara Trzebicka
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, 555, 539
DOI: 10.1016/j.colsurfa.2018.07.025

Cellular recycling-driven in vivo half-life extension using recombinant albumin fusions tuned for neonatal Fc receptor (FcRn) engagement
Maja Thim Larsen, Helen Rawsthorne, Karen Kræmmer Schelde, Frederik Dagnæs-Hansen, Jason Cameron and Kenneth A. Howard
Journal of Controlled Release, 2018, 287, 132
DOI: 10.1016/j.jconrel.2018.07.023

Harnessing Guanidinium and Imidazole Functional Groups: A Dual-Charged Polymer Strategy for Enhanced Gene Delivery
Prosper P. Mapfumo, Liên S. Reichel, Katharina Leer, Jan Egger, Andreas Dzierza, Kalina Peneva, Dagmar Fischer and Anja Traeger
ACS Macro Lett., 2024, 13, 1000
DOI: 10.1021/acsmacrolett.4c00321

Electrospinning a highly antibacterial polylactic acid/fibroin nanofiber membrane for wound dressings
Shuyi Zhou, Zixuan Liu, Yujuan Jin, Yansong Huang, Huafeng Tian and Hua Wu
International Journal of Biological Macromolecules, 2025, 310, 143230
DOI: 10.1016/j.ijbiomac.2025.143230

Functional Poly(2-oxazoline)s by Direct Amidation of Methyl Ester Side Chains
Maarten A. Mees and Richard Hoogenboom
Macromolecules, 2015, 48, 3531
DOI: 10.1021/acs.macromol.5b00290

The Label Matters: μPET Imaging of the Biodistribution of Low Molar Mass 89Zr and 18F-Labeled Poly(2-ethyl-2-oxazoline)
Mathias Glassner, Luca Palmieri, Bryn D. Monnery, Thomas Verbrugghen, Steven Deleye, Sigrid Stroobants, Steven Staelens, Leonie wyffels and Richard Hoogenboom
Biomacromolecules, 2017, 18, 96
DOI: 10.1021/acs.biomac.6b01392

Increasing the Hydrophilicity of Cyclic Ketene Acetals Improves the Hydrolytic Degradation of Vinyl Copolymers and the Interaction of Glycopolymer Nanoparticles with Lectins
Théo Pesenti, Emilie Gillon, Seika Ishii, Samir Messaoudi, Yohann Guillaneuf, Anne Imberty and Julien Nicolas
Biomacromolecules, 2023, 24, 991
DOI: 10.1021/acs.biomac.2c01419

Drug delivery’s quest for polymers: Where are the frontiers?
Hans P. Merkle
European Journal of Pharmaceutics and Biopharmaceutics, 2015, 97, 293
DOI: 10.1016/j.ejpb.2015.04.038

Isolation of Polyethylene Glycol with Larger Molecular Weights via Metal–Organic Frameworks
Yali Huang, Ziye Ren, Ziwen Fan, Hanwen Zhang, Yueyue Wu, Yue Wang, Zhuoyi Hu, Xueheng Quan, Zhao Wang and Zheng Niu
Macromol. Rapid Commun., 2024, 45
DOI: 10.1002/marc.202400535

Beyond Poly(ethylene glycol): Linear Polyglycerol as a Multifunctional Polyether for Biomedical and Pharmaceutical Applications
Anja Thomas, Sophie S. Müller and Holger Frey
Biomacromolecules, 2014, 15, 1935
DOI: 10.1021/bm5002608

Azo-capped polysarcosine-b-polylysine as polypeptide gene vector: A new strategy to improve stability and easy optimization via host–guest interaction
Jianwei Du, Ce Tian, Yajie Liu, Jun Ling and Youxiang Wang
Colloids and Surfaces B: Biointerfaces, 2015, 130, 31
DOI: 10.1016/j.colsurfb.2015.03.061

Site-Specific DBCO Modification of DEC205 Antibody for Polymer Conjugation
Simone Beck, Jennifer Schultze, Hans-Joachim Räder, Regina Holm, Meike Schinnerer, Matthias Barz, Kaloian Koynov and Rudolf Zentel
Polymers, 2018, 10, 141
DOI: 10.3390/polym10020141

A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform
Julian Schmidt, Anna‐Lena Ziegler, Florian T. Kaps, Laura J. Rosenberger, Matthias Bros, Holger Frey and Robert Luxenhofer
Macromol. Rapid Commun., 2025
DOI: 10.1002/marc.202500781

Directed Interactions of Block Copolypept(o)ides with Mannose‐binding Receptors: PeptoMicelles Targeted to Cells of the Innate Immune System
Philipp Heller, Nicole Mohr, Alexander Birke, Benjamin Weber, Angelika Reske‐Kunz, Matthias Bros and Matthias Barz
Macromolecular Bioscience, 2015, 15, 63
DOI: 10.1002/mabi.201400417

Poly(2‐oxazoline)s: a comprehensive overview of polymer structures and their physical properties—an update
Somdeb Jana and Richard Hoogenboom
Polymer International, 2022, 71, 935
DOI: 10.1002/pi.6426

Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: Preparation, in vitro and in vivo evaluation
Zhijian He, Anita Schulz, Xiaomeng Wan, Joshua Seitz, Herdis Bludau, Daria Y. Alakhova, David B. Darr, Charles M. Perou, Rainer Jordan, Iwao Ojima, Alexander V. Kabanov and Robert Luxenhofer
Journal of Controlled Release, 2015, 208, 67
DOI: 10.1016/j.jconrel.2015.02.024

Poly(2‐Oxazoline)s – Are They More Advantageous for Biomedical Applications Than Other Polymers?
Ondrej Sedlacek, Bryn D. Monnery, Sergey K. Filippov, Richard Hoogenboom and Martin Hruby
Macromol. Rapid Commun., 2012, 33, 1648
DOI: 10.1002/marc.201200453

Tuning the Thermogelation and Rheology of Poly(2-Oxazoline)/Poly(2-Oxazine)s Based Thermosensitive Hydrogels for 3D Bioprinting
Malik Salman Haider, Taufiq Ahmad, Mengshi Yang, Chen Hu, Lukas Hahn, Philipp Stahlhut, Jürgen Groll and Robert Luxenhofer
Gels, 2021, 7, 78
DOI: 10.3390/gels7030078

Introducing PeptoPlexes: Polylysine‐block‐Polysarcosine Based Polyplexes for Transfection of HEK 293T Cells
Philipp Heller, Alexander Birke, David Huesmann, Benjamin Weber, Karl Fischer, Angelika Reske‐Kunz, Matthias Bros and Matthias Barz
Macromolecular Bioscience, 2014, 14, 1380
DOI: 10.1002/mabi.201400167

Self-Assembly of Peptide Bioconjugates: Selected Recent Research Highlights
Ian W. Hamley and Valeria Castelletto
Bioconjugate Chem., 2017, 28, 731
DOI: 10.1021/acs.bioconjchem.6b00284

Oxygen-Promoted Suzuki-Miyaura Reaction for Efficient Construction of Biaryls
Chun Liu and Xinmin Li
The Chemical Record, 2016, 16, 84
DOI: 10.1002/tcr.201500218

ABA and BAB Triblock Copolymers Based on 2‐Methyl‐2‐oxazoline and 2‐n‐Propyl‐2‐oxazoline: Synthesis and Thermoresponsive Behavior in Water
Anna Zahoranová, Miroslav Mrlík, Katarína Tomanová, Juraj Kronek and Robert Luxenhofer
Macro Chemistry & Physics, 2017, 218
DOI: 10.1002/macp.201700031

Thermoresponsive Poly(2‐oxazoline) Molecular Brushes by Living Ionic Polymerization: Kinetic Investigations of Pendant Chain Grafting and Cloud Point Modulation by Backbone and Side Chain Length Variation
Ning Zhang, Robert Luxenhofer and Rainer Jordan
Macro Chemistry & Physics, 2012, 213, 973
DOI: 10.1002/macp.201200015

Administration, distribution, metabolism and elimination of polymer therapeutics
Ela Markovsky, Hemda Baabur-Cohen, Anat Eldar-Boock, Liora Omer, Galia Tiram, Shiran Ferber, Paula Ofek, Dina Polyak, Anna Scomparin and Ronit Satchi-Fainaro
Journal of Controlled Release, 2012, 161, 446
DOI: 10.1016/j.jconrel.2011.12.021

Synthesis, Characterization, and In Vitro Properties of Zwitterionic Dendrimers with a Reactive Focal Functionality for Biomedical Applications
Mingxuan Zhang, Masoud Zamani, Yafei Su, Ashley Miles, Ziwen Zhang, Emmanuel M. Nsengiyumva, Scott M. Grayson, Yun Wu and Chong Cheng
Langmuir, 2025, 41, 18229
DOI: 10.1021/acs.langmuir.5c02200

Design attributes of long-circulating polymeric drug delivery vehicles
Moritz Beck-Broichsitter, Julien Nicolas and Patrick Couvreur
European Journal of Pharmaceutics and Biopharmaceutics, 2015, 97, 304
DOI: 10.1016/j.ejpb.2015.03.033

Polymer-mediated protein/peptide therapeutic stabilization: Current progress and future directions
Rajalakshmi P. Sivasankaran, Katherine Snell, Grace Kunkel, Panagiotis G. Georgiou, Ellie G. Puente and Heather D. Maynard
Progress in Polymer Science, 2024, 156, 101867
DOI: 10.1016/j.progpolymsci.2024.101867

An assessment of biopolymer‐ and synthetic polymer‐based scaffolds for bone and vascular tissue engineering
Nowsheen Goonoo, Archana Bhaw‐Luximon, Gary L Bowlin and Dhanjay Jhurry
Polymer International, 2013, 62, 523
DOI: 10.1002/pi.4474

Analyses of functional polymer-modified nanoparticles for protein sensing by surface-assisted laser desorption/ionization mass spectrometry coupled with HgTe nanomatrices
Hsiang-Yu Chang, Ming-Feng Huang, Chia-Lun Hsu, Chih-Ching Huang and Huan-Tsung Chang
Colloids and Surfaces B: Biointerfaces, 2015, 130, 157
DOI: 10.1016/j.colsurfb.2015.04.001

Surface grafted glycopolymer brushes to enhance selective adhesion of HepG2 cells
Sergey Chernyy, Bettina E.B. Jensen, Kyoko Shimizu, Marcel Ceccato, Steen Uttrup Pedersen, Alexander N. Zelikin, Kim Daasbjerg and Joseph Iruthayaraj
Journal of Colloid and Interface Science, 2013, 404, 207
DOI: 10.1016/j.jcis.2013.04.025

Highly Defined Multiblock Copolypeptoids: Pushing the Limits of Living Nucleophilic Ring‐Opening Polymerization
Corinna Fetsch and Robert Luxenhofer
Macromol. Rapid Commun., 2012, 33, 1708
DOI: 10.1002/marc.201200189

Rare Earth Metal-Mediated Group-Transfer Polymerization: From Defined Polymer Microstructures to High-Precision Nano-Scaled Objects
Ning Zhang, Stephan Salzinger, Benedikt S. Soller and Bernhard Rieger
J. Am. Chem. Soc., 2013, 135, 8810
DOI: 10.1021/ja4036175

Poly(2-oxazoline)s as materials for biomedical applications
Victor R. de la Rosa
J Mater Sci: Mater Med, 2014, 25, 1211
DOI: 10.1007/s10856-013-5034-y

Polyglycidol of Linear or Branched Architecture Immobilized on a Solid Support for Biomedical Applications
Marcelina Bochenek, Natalia Oleszko-Torbus, Wojciech Wałach, Daria Lipowska-Kur, Andrzej Dworak and Alicja Utrata-Wesołek
Polymer Reviews, 2020, 60, 717
DOI: 10.1080/15583724.2020.1720233

Synthesis, structure, and optical properties of Fe2O3:PVA/PVP/PEG polymeric nanocomposite sheets for low-cost optical limiters under laser and solar visible lights
T. H. AlAbdulaal, W. Abdullah and I. S. Yahia
J Mater Sci: Mater Electron, 2025, 36
DOI: 10.1007/s10854-025-15871-z

Polymer–drug conjugates as nano-sized medicines
Fabiana Canal, Joaquin Sanchis and María J Vicent
Current Opinion in Biotechnology, 2011, 22, 894
DOI: 10.1016/j.copbio.2011.06.003

Novel development of Poly(2-ethyl-2-oxazoline)-based mucoadhesive buccal film for poorly water-soluble drug delivery via hot-melt extrusion
Ziru Zhang, Sheng Feng, Rasha El-Kanayati, Indrajeet Karnik, Sateesh Kumar Vemula and Michael A. Repka
European Journal of Pharmaceutics and Biopharmaceutics, 2025, 210, 114686
DOI: 10.1016/j.ejpb.2025.114686

Poly(2-oxazoline)-Based Nanogels as Biocompatible Pseudopolypeptide Nanoparticles
Camille Legros, Anne-Laure Wirotius, Marie-Claire De Pauw-Gillet, Kam Chiu Tam, Daniel Taton and Sébastien Lecommandoux
Biomacromolecules, 2015, 16, 183
DOI: 10.1021/bm501393q

Image‐guided tumor surgery: will there be a role for fluorescent nanoparticles?
Tanner K. Hill and Aaron M. Mohs
WIREs Nanomed Nanobiotechnol, 2016, 8, 498
DOI: 10.1002/wnan.1381

On the design of precision nanomedicines
Xiaohe Tian, Stefano Angioletti-Uberti and Giuseppe Battaglia
Sci. Adv., 2020, 6
DOI: 10.1126/sciadv.aat0919

Polymerization of Ethylene Oxide, Propylene Oxide, and Other Alkylene Oxides: Synthesis, Novel Polymer Architectures, and Bioconjugation
Jana Herzberger, Kerstin Niederer, Hannah Pohlit, Jan Seiwert, Matthias Worm, Frederik R. Wurm and Holger Frey
Chem. Rev., 2016, 116, 2170
DOI: 10.1021/acs.chemrev.5b00441

Recent developments in the use of gold and silver nanoparticles in biomedicine
George Pasparakis
WIREs Nanomed Nanobiotechnol, 2022, 14
DOI: 10.1002/wnan.1817

Free PEG Suppresses Anaphylaxis to PEGylated Nanomedicine in Swine
Limei Shen, Zhongbo Li, Alice Ma, Carlos Cruz-Teran, Anne Talkington, Steven T. Shipley and Samuel K. Lai
ACS Nano, 2024, 18, 8733
DOI: 10.1021/acsnano.3c11165

Poly(S-ethylsulfonyl-l-cysteines) for Chemoselective Disulfide Formation
Olga Schäfer, David Huesmann and Matthias Barz
Macromolecules, 2016, 49, 8146
DOI: 10.1021/acs.macromol.6b02064

Poly(2-oxazoline) block copolymer nanoparticles for curcumin loading and delivery to cancer cells
Radhika Raveendran, Kathleen M. Mullen, R. Mark Wellard, Chandra P. Sharma, Richard Hoogenboom and Tim R. Dargaville
European Polymer Journal, 2017, 93, 682
DOI: 10.1016/j.eurpolymj.2017.02.043

Polyaminoacid-based nanocarriers: a review of the latest candidates for oral drug delivery
Sandra Robla, Maria José Alonso and Noemi S. Csaba
Expert Opinion on Drug Delivery, 2020, 17, 1081
DOI: 10.1080/17425247.2020.1776698

Modulation of immunogenicity of poly(sarcosine) displayed on various nanoparticle surfaces due to different physical properties
Cheol Joo Kim, Eri Hara, Naoki Watabe, Isao Hara and Shunsaku Kimura
Journal of Peptide Science, 2017, 23, 889
DOI: 10.1002/psc.3053

Not Just for Tumor Targeting: Unmet Medical Needs and Opportunities for Nanomedicine
Elise Lepeltier, Lutz Nuhn, Claus-Michael Lehr and Rudolf Zentel
Nanomedicine (Lond.), 2015, 10, 3147
DOI: 10.2217/nnm.15.132

Impact of the polymer backbone chemistry on interactions of amino-acid-derived zwitterionic polymers with cells
Meike N. Leiske, Bruno G. De Geest and Richard Hoogenboom
Bioactive Materials, 2023, 24, 524
DOI: 10.1016/j.bioactmat.2023.01.005

Complexity and Simplification in the Development of Nanomedicines
Matthias Barz
Nanomedicine (Lond.), 2015, 10, 3093
DOI: 10.2217/nnm.15.146

Facile Generation of Heterotelechelic Poly(2‐Oxazoline)s Towards Accelerated Exploration of Poly(2‐Oxazoline)‐Based Nanomedicine
Joachim F. R. Van Guyse, Saed Abbasi, Kazuko Toh, Zlata Nagorna, Junjie Li, Anjaneyulu Dirisala, Sabina Quader, Satoshi Uchida and Kazunori Kataoka
Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202404972

A New Way to Silicone‐Based Peptide Polymers
Said Jebors, Jeremie Ciccione, Soultan Al‐Halifa, Benjamin Nottelet, Christine Enjalbal, Céline M'Kadmi, Muriel Amblard, Ahmad Mehdi, Jean Martinez and Gilles Subra
Angewandte Chemie, 2015, 127, 3849
DOI: 10.1002/ange.201411065

On the biodegradability of polyethylene glycol, polypeptoids and poly(2-oxazoline)s
Juliane Ulbricht, Rainer Jordan and Robert Luxenhofer
Biomaterials, 2014, 35, 4848
DOI: 10.1016/j.biomaterials.2014.02.029

Sweet Polymers: Poly(2-ethyl-2-oxazoline) Glycopolymers by Reductive Amination
Maarten A. Mees, Christiane Effenberg, Dietmar Appelhans and Richard Hoogenboom
Biomacromolecules, 2016, 17, 4027
DOI: 10.1021/acs.biomac.6b01451

Reduction Sensitive Poly(l-glutamic acid) (PGA)-Protein Conjugates Designed for Polymer Masked–Unmasked Protein Therapy
Marina Talelli and María J. Vicent
Biomacromolecules, 2014, 15, 4168
DOI: 10.1021/bm5011883

Recent developments in polymer–block–polypeptide and protein–polymer bioconjugate hybrid materials
Renjith P. Johnson, Johnson V. John and Il Kim
European Polymer Journal, 2013, 49, 2925
DOI: 10.1016/j.eurpolymj.2013.04.017

Amphiphilic nonionic block and gradient copoly(2-oxazoline)s based on 2-methyl-2-oxazoline and 2-phenyl-2-oxazoline as efficient stabilizers for the formulation of tailor-made emulsions
Valentin Bardoula, Loïc Leclercq, Richard Hoogenboom and Véronique Nardello-Rataj
Journal of Colloid and Interface Science, 2023, 632, 223
DOI: 10.1016/j.jcis.2022.11.018

Combining Core Cross-Linking and π–π-Interactions in Polymer Micelles Based on Polypept(o)ide AB3 Miktoarm Star Polymers
David T. Schwiertz, Gabriela Schäfer and Matthias Barz
Macromolecules, 2025, 58, 4225
DOI: 10.1021/acs.macromol.4c02708

Anionic flow polymerizations toward functional polyphosphoesters in microreactors: Polymerization and UV-modification
Evelien Baeten, Stephanie Vanslambrouck, Christine Jérôme, Philippe Lecomte and Tanja Junkers
European Polymer Journal, 2016, 80, 208
DOI: 10.1016/j.eurpolymj.2016.02.012

Side-Chain Cysteine-Functionalized Poly(2-oxazoline)s for Multiple Peptide Conjugation by Native Chemical Ligation
Michael Schmitz, Matthias Kuhlmann, Oliver Reimann, Christian P. R. Hackenberger and Jürgen Groll
Biomacromolecules, 2015, 16, 1088
DOI: 10.1021/bm501697t

Nanoparticle Probes for the Detection of Cancer Biomarkers, Cells, and Tissues by Fluorescence
Alyssa B. Chinen, Chenxia M. Guan, Jennifer R. Ferrer, Stacey N. Barnaby, Timothy J. Merkel and Chad A. Mirkin
Chem. Rev., 2015, 115, 10530
DOI: 10.1021/acs.chemrev.5b00321

Poly(Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes
Stefan Bleher, Jonas Buck, Christian Muhl, Sandro Sieber, Sabine Barnert, Dominik Witzigmann, Jörg Huwyler, Matthias Barz and Regine Süss
Small, 2019, 15
DOI: 10.1002/smll.201904716

Poly(2‐oxazoline) Hydrogel Monoliths via Thiol‐ene Coupling
Tim R. Dargaville, Rebecca Forster, Brooke L. Farrugia, Kristian Kempe, Lenny Voorhaar, Ulrich S. Schubert and Richard Hoogenboom
Macromol. Rapid Commun., 2012, 33, 1695
DOI: 10.1002/marc.201200249

Role of Hydrophilicity and Length of Diblock Arms for Determining Star Polymer Physical Properties
Lisa E. Felberg, David H. Brookes, Teresa Head-Gordon, Julia E. Rice and William C. Swope
J. Phys. Chem. B, 2015, 119, 944
DOI: 10.1021/jp506203k

Improving aqueous solubility of paclitaxel with polysarcosine-b-poly(γ-benzyl glutamate) nanoparticles
Coralie Lebleu, Laetitia Plet, Florène Moussy, Gaëtan Gitton, Rudy Da Costa Moreira, Ludmilla Guduff, Barbara Burlot, Rodolphe Godiveau, Aïnhoa Merry, Sébastien Lecommandoux, Gauthier Errasti, Christiane Philippe, Thomas Delacroix and Raj Chakrabarti
International Journal of Pharmaceutics, 2023, 631, 122501
DOI: 10.1016/j.ijpharm.2022.122501

Recent Developments and Perspectives on Gene Therapy Using Synthetic Vectors
Florian Schlenk, Stefan Grund and Dagmar Fischer
Therapeutic Delivery, 2013, 4, 95
DOI: 10.4155/tde.12.128

Synthesis and Self‐Assembly of Perylene Imide‐Containing Hydrophilic Polymers in Water
Sébastien Berruée, Jutta Rieger and Lydia Sosa Vargas
Chemistry A European J, 2026, 32
DOI: 10.1002/chem.202503564

Thermoresponsive Poly(2‐Oxazoline) Molecular Brushes by Living Ionic Polymerization: Modulation of the Cloud Point by Random and Block Copolymer Pendant Chains
Ning Zhang, Robert Luxenhofer and Rainer Jordan
Macro Chemistry & Physics, 2012, 213, 1963
DOI: 10.1002/macp.201200261

Anti-Cancer Activity Based on the High Docetaxel Loaded Poly(2-Oxazoline)s Micelles
Min Xu, Chong Yao, Wei Zhang, Shen Gao, Hao Zou and Jing Gao
IJN, 2021, Volume 16, 2735
DOI: 10.2147/IJN.S298093

Functionalizable Hydrophilic Polycarbonate, Poly(5-methyl-5-(2-hydroxypropyl)aminocarbonyl-1,3-dioxan-2-one), Designed as a Degradable Alternative for PHPMA and PEG
Sangho Cho, Gyu Seong Heo, Sarosh Khan, Amelia M. Gonzalez, Mahmoud Elsabahy and Karen L. Wooley
Macromolecules, 2015, 48, 8797
DOI: 10.1021/acs.macromol.5b01974

Complementary Supramolecular Functionalization Enhances Antifouling Surfaces: A Ureidopyrimidinone-Functionalized Phosphorylcholine Polymer
Antonio J. Feliciano, Eduardo Soares, Anton W. Bosman, Clemens van Blitterswijk, Lorenzo Moroni, Vanessa L. S. LaPointe and Matthew B. Baker
ACS Biomater. Sci. Eng., 2023, 9, 4619
DOI: 10.1021/acsbiomaterials.3c00425

Investigation of α-amino acid N-carboxyanhydrides by X-ray diffraction for controlled ring-opening polymerization
Olga Schäfer, Dieter Schollmeyer, Alexander Birke, Regina Holm, Kerstin Johann, Christian Muhl, Christine Seidl, Benjamin Weber and Matthias Barz
Tetrahedron Letters, 2019, 60, 272
DOI: 10.1016/j.tetlet.2018.12.028

Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles
Mark J. Ernsting, Mami Murakami, Aniruddha Roy and Shyh-Dar Li
Journal of Controlled Release, 2013, 172, 782
DOI: 10.1016/j.jconrel.2013.09.013

PEG-Lipids: Quantitative Study of Unimers and Aggregates Thereof by the Methods of Molecular Hydrodynamics
Ilya Anufriev, Stephanie Hoeppener and Ivo Nischang
Anal. Chem., 2023, 95, 10795
DOI: 10.1021/acs.analchem.3c01999

Novel triphilic block copolymers based on poly(2-methyl-2-oxazoline)–block–poly(2-octyl-2-oxazoline) with different terminal perfluoroalkyl fragments: Synthesis and self-assembly behaviour
Leonid I. Kaberov, Bart Verbraeken, Martin Hruby, Anna Riabtseva, Lubomir Kovacik, Sami Kereïche, Jiri Brus, Petr Stepanek, Richard Hoogenboom and Sergey K. Filippov
European Polymer Journal, 2017, 88, 645
DOI: 10.1016/j.eurpolymj.2016.10.016

Model-Based Visualization and Understanding of Monomer Sequence Formation in Gradient Copoly(2-oxazoline)s On the basis of 2-Methyl-2-oxazoline and 2-Phenyl-2-oxazoline
Paul H. M. Van Steenberge, Bart Verbraeken, Marie-Françoise Reyniers, Richard Hoogenboom and Dagmar R. D’hooge
Macromolecules, 2015, 48, 7765
DOI: 10.1021/acs.macromol.5b01642

Formulation of Carbopol®/Poly(2-ethyl-2-oxazoline)s Mucoadhesive Tablets for Buccal Delivery of Hydrocortisone
Leire Ruiz-Rubio, María Alonso, Leyre Pérez-Álvarez, Rosa Alonso, Jose Vilas and Vitaliy Khutoryanskiy
Polymers, 2018, 10, 175
DOI: 10.3390/polym10020175

Hyperbranched aliphatic polyether polyols
Martina Schömer, Christoph Schüll and Holger Frey
J. Polym. Sci. A Polym. Chem., 2013, 51, 995
DOI: 10.1002/pola.26496

Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging
E. Johanna L. Stéen, Jesper T. Jørgensen, Ida N. Petersen, Kamilla Nørregaard, Szabolcs Lehel, Vladimir Shalgunov, Alexander Birke, Patricia E. Edem, Elina T. L'Estrade, Hanne D. Hansen, Jonas Villadsen, Maria Erlandsson, Tomas Ohlsson, Abdolreza Yazdani, John F. Valliant, Jesper L. Kristensen, Matthias Barz, Gitte M. Knudsen, Andreas Kjær and Matthias M. Herth
Bioorganic & Medicinal Chemistry Letters, 2019, 29, 986
DOI: 10.1016/j.bmcl.2019.02.014

Soft Hydrogel Zwitterionic Coatings Minimize Fibroblast and Macrophage Adhesion on Polyimide Substrates
Dušana Trel’ová, Alice Rita Salgarella, Leonardo Ricotti, Guido Giudetti, Annarita Cutrone, Petra Šrámková, Anna Zahoranová, Dušan Chorvát, Daniel Haško, Claudio Canale, Silvestro Micera, Juraj Kronek, Arianna Menciassi and Igor Lacík
Langmuir, 2019, 35, 1085
DOI: 10.1021/acs.langmuir.8b00765

Multireactive Poly(2-oxazoline) Nanofibers through Electrospinning with Crosslinking on the Fly
Ozlem I. Kalaoglu-Altan, Bart Verbraeken, Kathleen Lava, Tugce Nihal Gevrek, Rana Sanyal, Tim Dargaville, Karen De Clerck, Richard Hoogenboom and Amitav Sanyal
ACS Macro Lett., 2016, 5, 676
DOI: 10.1021/acsmacrolett.6b00188

Polypeptoid Materials: Current Status and Future Perspectives
Donghui Zhang, Samuel H. Lahasky, Li Guo, Chang-Uk Lee and Monika Lavan
Macromolecules, 2012, 45, 5833
DOI: 10.1021/ma202319g

Aldehyde-functional copolymers based on poly(2-oxazoline) for post-polymerization modification
Camille Legros, Marie-Claire De Pauw-Gillet, Kam Chiu Tam, Sébastien Lecommandoux and Daniel Taton
European Polymer Journal, 2015, 62, 322
DOI: 10.1016/j.eurpolymj.2014.08.026

Secondary Structure-Driven Self-Assembly of Thiol-Reactive Polypept(o)ides
Tobias A. Bauer, Jan Imschweiler, Christian Muhl, Benjamin Weber and Matthias Barz
Biomacromolecules, 2021, 22, 2171
DOI: 10.1021/acs.biomac.1c00253

Terminal end groups of poly(ethylene glycol) reduce antigenicity
Kouichi Shiraishi
Polym J, 2026, 58, 461
DOI: 10.1038/s41428-025-01128-3

Chemische Ansätze für synthetische Wirkstofftransportsysteme für systemische Anwendungen
Daniel Braatz, Mariam Cherri, Michael Tully, Mathias Dimde, Guoxin Ma, Ehsan Mohammadifar, Felix Reisbeck, Vahid Ahmadi, Michael Schirner and Rainer Haag
Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202203942

Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models
Nils-Jørgen K. Dal, Gabriela Schäfer, Andrew M. Thompson, Sascha Schmitt, Natalja Redinger, Noelia Alonso-Rodriguez, Kerstin Johann, Jessica Ojong, Jens Wohlmann, Andreas Best, Kaloian Koynov, Rudolf Zentel, Ulrich E. Schaible, Gareth Griffiths, Matthias Barz and Federico Fenaroli
Journal of Controlled Release, 2023, 354, 851
DOI: 10.1016/j.jconrel.2023.01.037

Peptide‐Assisted Design of Precision Polymer Sequences: On the Relevance of the Side‐Chain Sequences and the Variability of the Backbone
Sensu Celasun, Eva Maron and Hans G. Börner
Macromolecular Bioscience, 2020, 20
DOI: 10.1002/mabi.201900244

A head-to-head comparison of poly(sarcosine) and poly(ethylene glycol) in peptidic, amphiphilic block copolymers
David Huesmann, Adrian Sevenich, Benjamin Weber and Matthias Barz
Polymer, 2015, 67, 240
DOI: 10.1016/j.polymer.2015.04.070

Bio-inspired hemocompatible surface modifications for biomedical applications
Megan Douglass, Mark Garren, Ryan Devine, Arnab Mondal and Hitesh Handa
Progress in Materials Science, 2022, 130, 100997
DOI: 10.1016/j.pmatsci.2022.100997

Peptide-Based Polymer Therapeutics
Aroa Duro-Castano, Inmaculada Conejos-Sánchez and María Vicent
Polymers, 2014, 6, 515
DOI: 10.3390/polym6020515

Building better biobetters: From fundamentals to industrial application
Karin M. Torres-Obreque, Giovanna P. Meneguetti, Jorge J. Muso-Cachumba, Valker A. Feitosa, João H.P.M. Santos, Sónia P.M. Ventura and Carlota O. Rangel-Yagui
Drug Discovery Today, 2022, 27, 65
DOI: 10.1016/j.drudis.2021.08.009

First Symposium on Poly(2‐oxazoline)s and Related Pseudo‐Polypeptide Structures
Victor R. de la Rosa, Petra J. M. Bouten and Richard Hoogenboom
Macro Chemistry & Physics, 2012, 213, 2669
DOI: 10.1002/macp.201200534

Investigating the stability of RNA-lipid nanoparticles in biological fluids: Unveiling its crucial role for understanding LNP performance
Heyang Zhang and Matthias Barz
Journal of Controlled Release, 2025, 381, 113559
DOI: 10.1016/j.jconrel.2025.02.055

Long-term biodistribution study of HPMA- ran -LMA copolymers in vivo by means of 131 I-labeling
Karolin Wagener, Dorothea Moderegger, Mareli Allmeroth, Achim Reibel, Stefan Kramer, Barbara Biesalski, Nicole Bausbacher, Rudolf Zentel, Oliver Thews and Frank Rösch
Nuclear Medicine and Biology, 2018, 58, 59
DOI: 10.1016/j.nucmedbio.2017.12.002

Amphiphilic gradient copolymers of 2‐methyl‐ and 2‐phenyl‐2‐oxazoline: self‐organization in aqueous media and drug encapsulation
Yanna Milonaki, Eleni Kaditi, Stergios Pispas and Costas Demetzos
J. Polym. Sci. A Polym. Chem., 2012, 50, 1226
DOI: 10.1002/pola.25888

Pharmacokinetics of nanotechnology-based formulations in pediatric populations
Venkata K. Yellepeddi, Andrea Joseph and Elizabeth Nance
Advanced Drug Delivery Reviews, 2019, 151-152, 44
DOI: 10.1016/j.addr.2019.08.008

Zwitterionic Amino‐Acid‐Derived Polyacrylamides with a Betaine Twist – Synthesis and Characterization
Jonas De Breuck, Valérie Jérôme, Ruth Freitag and Meike N. Leiske
Macromol. Rapid Commun., 2025, 46
DOI: 10.1002/marc.202400623

Agile delivery of protein therapeutics to CNS
Xiang Yi, Devika S. Manickam, Anna Brynskikh and Alexander V. Kabanov
Journal of Controlled Release, 2014, 190, 637
DOI: 10.1016/j.jconrel.2014.06.017

Sulfolane as Common Rate Accelerating Solvent for the Cationic Ring-Opening Polymerization of 2-Oxazolines
Maarten Vergaelen, Bart Verbraeken, Bryn D. Monnery and Richard Hoogenboom
ACS Macro Lett., 2015, 4, 825
DOI: 10.1021/acsmacrolett.5b00392

Single-Chain Studies Reveal that Neutral Poly(2-ethyl-2-oxazoline) Exhibits Polyelectrolyte-like Behavior in Aqueous Solutions
Wentao Yuan, Hongyu Ju, Lu Qian, Lei Zhang, Hu-jun Qian, Zhong-yuan Lu, Yu Bao and Shuxun Cui
Polymer Science & Technology, 2025
DOI: 10.1021/polymscitech.5c00051

Liquid crystalline nanoparticles for drug delivery: The role of gradient and block copolymers on the morphology, internal organisation and release profile
Maria Chountoulesi, Diego Romano Perinelli, Aleksander Forys, Giulia Bonacucina, Barbara Trzebicka, Stergios Pispas and Costas Demetzos
European Journal of Pharmaceutics and Biopharmaceutics, 2021, 158, 21
DOI: 10.1016/j.ejpb.2020.08.008

The Topology of Poly(2-methyl-2-oxazine) Shells on Nanoparticles Determines Their Interaction with Serum and Uptake by Immune Cells
Maria Morbidelli, Matteo Romio, Yashoda Chandorkar, Alexander Gogos, Cordula Hirsch, Barbora Kolrosova, Lucca Trachsel, Francesca Lorandi, Denis Badocco, Paolo Pastore, Giorgio Arrigoni, Cinzia Franchin, Regina Tavano, Richard Hoogenboom, Emanuele Papini and Edmondo M. Benetti
Biomacromolecules, 2025, 26, 556
DOI: 10.1021/acs.biomac.4c01340

Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood
Meike N. Leiske, May Lai, Thakshila Amarasena, Thomas P. Davis, Kristofer J. Thurecht, Stephen J. Kent and Kristian Kempe
Biomaterials, 2021, 274, 120843
DOI: 10.1016/j.biomaterials.2021.120843

PLA‐b‐SMA as an Amphiphilic Diblock Copolymer for Encapsulation of Lipophilic Cargo
Lauren E. Ball, Rueben Pfukwa, Raoni P. Siqueira, Vanessa C. F. Mosqueira and Bert Klumperman
Macro Chemistry & Physics, 2023, 224
DOI: 10.1002/macp.202200212

Synergistic Combinations of Multiple Chemotherapeutic Agents in High Capacity Poly(2-oxazoline) Micelles
Yingchao Han, Zhijian He, Anita Schulz, Tatiana K. Bronich, Rainer Jordan, Robert Luxenhofer and Alexander V. Kabanov
Mol. Pharmaceutics, 2012, 9, 2302
DOI: 10.1021/mp300159u

Boronic Ester Cross-Linked Star Polyoxazoline Hydrogels with Self-Healing and Stimuli-Responsive Behavior
Sophia Loeffelsend and Juergen Groll
Biomacromolecules, 2026, 27, 337
DOI: 10.1021/acs.biomac.5c01466

The roles of polymers in mRNA delivery
Pei Huang, Hongzhang Deng, Yongfeng Zhou and Xiaoyuan Chen
Matter, 2022, 5, 1670
DOI: 10.1016/j.matt.2022.03.006

Amphiphilic Zwitterionic Bioderived Block Copolymers from Glutamic Acid and Cholesterol – Ability to Form Nanoparticles and Serve as Vectors for the Delivery of 6‐Mercaptopurine
Meike N. Leiske, Christopher Kuenneth, Jonas De Breuck, Bruno G. De Geest and Richard Hoogenboom
Macro Chemistry & Physics, 2023, 224
DOI: 10.1002/macp.202300200

Polypept(o)ides – Origins, synthesis, applications and future directions
Tobias Alexander Bauer, Leon Simić, Joachim F.R. Van Guyse, Aroa Duro-Castaño, Vicent J. Nebot and Matthias Barz
Progress in Polymer Science, 2024, 158, 101889
DOI: 10.1016/j.progpolymsci.2024.101889

PEG-Free Polyion Complex Nanocarriers for Brain-Derived Neurotrophic Factor
James M. Fay, Chaemin Lim, Anna Finkelstein, Elena V. Batrakova and Alexander V. Kabanov
Pharmaceutics, 2022, 14, 1391
DOI: 10.3390/pharmaceutics14071391

New Perspectives of HPMA‐based Copolymers Derived by Post‐Polymerization Modification
Lutz Nuhn, Matthias Barz and Rudolf Zentel
Macromolecular Bioscience, 2014, 14, 607
DOI: 10.1002/mabi.201400028

Synthesis of Amphiphilic Block Copolypept(o)ides by Bifunctional Initiators: Making PeptoMicelles Redox Sensitive
Regina Holm, Kristina Klinker, Benjamin Weber and Matthias Barz
Macromol. Rapid Commun., 2015, 36, 2083
DOI: 10.1002/marc.201500402

Next‐Generation Polymeric Nanomedicines for Oncology: Perspectives and Future Directions
Nicholas L. Fletcher, Kristian Kempe and Kristofer J. Thurecht
Macromol. Rapid Commun., 2020, 41
DOI: 10.1002/marc.202000319

A Transient Initiator for Polypeptoids Postpolymerization α‐Functionalization via Activation of a Thioester Group
Solomiia Borova, Christine Schlutt, Joachim Nickel and Robert Luxenhofer
Macro Chemistry & Physics, 2022, 223
DOI: 10.1002/macp.202100331

Synthetic chemical ligands and cognate antibodies for biorthogonal drug targeting and cell engineering
Pere Monge, Ane Bretschneider Søgaard, Dante Guldbrandsen Andersen, Rona Chandrawati and Alexander N. Zelikin
Advanced Drug Delivery Reviews, 2021, 170, 281
DOI: 10.1016/j.addr.2021.01.010

Interpolyelectrolyte Complexes as an Emerging Technology for Pharmaceutical Delivery of Polypeptides
James M. Fay and Alexander V. Kabanov
rev. and adv. in chem., 2022, 12, 137
DOI: 10.1134/S2634827622600177

H-bonding binary organocatalysis promoted amine-initiated ring-opening polymerizations of lactide from polysarcosine to diblock copolymers
Siming Chen, Yaya Liu, Zhenjiang Li, Xin Wang, He Dong, Herui Sun, Kun Yang, Hailemariam Gebru and Kai Guo
European Polymer Journal, 2017, 97, 389
DOI: 10.1016/j.eurpolymj.2017.10.030

Advance in Hybrid Peptides Synthesis
Jingcheng Zou, Min Zhou, Ximian Xiao and Runhui Liu
Macromol. Rapid Commun., 2022, 43
DOI: 10.1002/marc.202200575

Makromolekulare Chemie 2011

Nachr Chem, 2012, 60, 332
DOI: 10.1002/nadc.201290123

Poly(2-oxazoline)s based biomaterials: A comprehensive and critical update
Thomas Lorson, Michael M. Lübtow, Erik Wegener, Malik S. Haider, Solomiia Borova, Daniel Nahm, Rainer Jordan, Marina Sokolski-Papkov, Alexander V. Kabanov and Robert Luxenhofer
Biomaterials, 2018, 178, 204
DOI: 10.1016/j.biomaterials.2018.05.022

Micelles with Sheddable Dendritic Polyglycerol Sulfate Shells Show Extraordinary Tumor Targetability and Chemotherapy in Vivo
Yinan Zhong, Mathias Dimde, Daniel Stöbener, Fenghua Meng, Chao Deng, Zhiyuan Zhong and Rainer Haag
ACS Appl. Mater. Interfaces, 2016, 8, 27530
DOI: 10.1021/acsami.6b09204

The future of poly(2-oxazoline)s
Richard Hoogenboom
European Polymer Journal, 2022, 179, 111521
DOI: 10.1016/j.eurpolymj.2022.111521

Polypeptoid-block-polypeptide Copolymers: Synthesis, Characterization, and Application of Amphiphilic Block Copolypept(o)ides in Drug Formulations and Miniemulsion Techniques
Alexander Birke, David Huesmann, Annette Kelsch, Martin Weilbächer, Jing Xie, Matthias Bros, Tobias Bopp, Christian Becker, Katharina Landfester and Matthias Barz
Biomacromolecules, 2014, 15, 548
DOI: 10.1021/bm401542z

Nucleic Acids as a Nature‐Inspired Scaffold for Macromolecular Prodrugs of Nucleoside Analogues
Franziska Krüger, Vipin Kumar, Pere Monge, Carina Conzelmann, Nikaïa Smith, Kurt V. Gothelf, Martin Tolstrup, Jan Münch and Alexander N. Zelikin
Advanced Science, 2019, 6
DOI: 10.1002/advs.201802095

Customization of protein corona to reprogram cancer nanomedicines: Mechanistic insights and therapeutic implications
Yiming Lu, Yixin Sun, Dongyu Zhang, Zhonggui He, Bingjun Sun and Jin Sun
Journal of Controlled Release, 2025, 386, 114154
DOI: 10.1016/j.jconrel.2025.114154

Advances in Bioactive Hydrogels to Probe and Direct Cell Fate
Cole A. DeForest and Kristi S. Anseth
Annu. Rev. Chem. Biomol. Eng., 2012, 3, 421
DOI: 10.1146/annurev-chembioeng-062011-080945

Design of Poly(ethylene Glycol)-Functionalized Hydrophilic Carbon Clusters for Targeted Therapy of Cerebrovascular Dysfunction in Mild Traumatic Brain Injury
Daniela C. Marcano, Brittany R. Bitner, Jacob M. Berlin, Jane Jarjour, Juhye M. Lee, Aakash Jacob, Roderic H. Fabian, Thomas A. Kent and James M. Tour
Journal of Neurotrauma, 2013, 30, 789
DOI: 10.1089/neu.2011.2301

Blending Carbohydrate and Quinine-Based Polymers Imparts Colloidal Stability, Improved Performance, and Cell Specificity for mRNA Delivery
Nicholas W. Kreofsky, Punarbasu Roy, Ruma Ghosh, Sidharth Panda, Can Sarisozen and Theresa M. Reineke
Biomacromolecules, 2025, 26, 6635
DOI: 10.1021/acs.biomac.5c00901

RAFT Agent Design and Synthesis
Daniel J. Keddie, Graeme Moad, Ezio Rizzardo and San H. Thang
Macromolecules, 2012, 45, 5321
DOI: 10.1021/ma300410v

Hydroxyl Group Tolerated Polymerization of N-Substituted Glycine N-Thiocarboxyanhydride Mediated by Aminoalcohols: A Simple Way to α-Hydroxyl-ω-aminotelechelic Polypeptoids
Xinfeng Tao, Botuo Zheng, Tianwen Bai, Baoku Zhu and Jun Ling
Macromolecules, 2017, 50, 3066
DOI: 10.1021/acs.macromol.7b00309

Poly(2-oxazoline) hydrogels as next generation three-dimensional cell supports
Tim R Dargaville, Brett G Hollier, Ali Shokoohmand and Richard Hoogenboom
Cell Adhesion & Migration, 2014, 8, 88
DOI: 10.4161/cam.28205

Polymer Nanocompartments in Broad-Spectrum Medical Applications
Adrian Najer, Dalin Wu, Daniela Vasquez, Cornelia G Palivan and Wolfgang Meier
Nanomedicine, 2013, 8, 425
DOI: 10.2217/nnm.13.11

Think Beyond the Core: Impact of the Hydrophilic Corona on Drug Solubilization Using Polymer Micelles
Malik Salman Haider, Michael M. Lübtow, Sebastian Endres, Stefan Forster, Vanessa J. Flegler, Bettina Böttcher, Vladimir Aseyev, Ann-Christin Pöppler and Robert Luxenhofer
ACS Appl. Mater. Interfaces, 2020, 12, 24531
DOI: 10.1021/acsami.9b22495

Poly(2-oxazoline)-derived star-shaped polymers as potential materials for biomedical applications: A review
Meike N. Leiske
European Polymer Journal, 2023, 185, 111832
DOI: 10.1016/j.eurpolymj.2023.111832

Biodegradable zwitterionic polymers as PEG alternatives for drug delivery
Ziwen Zhang, Haotian Sun, Justin Giannino, Yun Wu and Chong Cheng
Journal of Polymer Science, 2024, 62, 2231
DOI: 10.1002/pol.20230916

Uni‐molecular nanoparticles of poly(2‐oxazoline) showing tunable thermoresponsive behaviors
Yuehuan Chu, Huaan Li, Huahua Huang, Houbo Zhou, Yi Chen, Böckler Andreas, Lixin Liu and Yongming Chen
J. Polym. Sci. Part A: Polym. Chem., 2018, 56, 174
DOI: 10.1002/pola.28889

Codelivery of miR-4638–5p and Docetaxel Based on Redox-Sensitive Polypeptide Micelles as an Improved Strategy for the Treatment of Castration-Resistant Prostate Cancer
Wenjun Jiang, Yuan Gao, Zhuo Wang, Chunai Gong, Chuling Hu, Xueying Ding, Lei Qiang, Shen Gao and Fuzheng Ren
Mol. Pharmaceutics, 2019, 16, 437
DOI: 10.1021/acs.molpharmaceut.8b01074

Determination of ω -end functionalities in tailored poly(2-alkyl-2-oxazoline)s by liquid chromatography and mass spectrometry
Nora Engel, Michael Dirauf, Justyna A. Czaplewska, Ivo Nischang, Michael Gottschaldt and Ulrich S. Schubert
R. Soc. Open Sci., 2024, 11
DOI: 10.1098/rsos.231008

Application of Sortase‐Mediated Ligation for the Synthesis of Block Copolymers and Protein‐Polymer Conjugates
Johannes Martin, Marcus Michaelis, Saša Petrović, Anne‐Catherine Lehnen, Yannic Müllers, Petra Wendler, Heiko M. Möller, Matthias Hartlieb and Ulrich Glebe
Macromolecular Bioscience, 2025, 25
DOI: 10.1002/mabi.202400316

Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo
Paul Strasser, Bianca Montsch, Silvia Weiss, Haider Sami, Christoph Kugler, Sonja Hager, Hemma Schueffl, Robert Mader, Oliver Brüggemann, Christian R. Kowol, Manfred Ogris, Petra Heffeter and Ian Teasdale
Small, 2023, 19
DOI: 10.1002/smll.202300767

1,1,3,3-Tetramethylguanidine-Promoted Ring-Opening Polymerization of N-Butyl N-Carboxyanhydride Using Alcohol Initiators
Brandon A. Chan, Sunting Xuan, Matthew Horton and Donghui Zhang
Macromolecules, 2016, 49, 2002
DOI: 10.1021/acs.macromol.5b02520

Systematic Study of Perfluorocarbon Nanoemulsions Stabilized by Polymer Amphiphiles
Rachael A. Day, Daniel A. Estabrook, Carolyn Wu, John O. Chapman, Alyssa J. Togle and Ellen M. Sletten
ACS Appl. Mater. Interfaces, 2020, 12, 38887
DOI: 10.1021/acsami.0c07206

Zwitterionic Amino Acid-Derived Polyacrylates as Smart Materials Exhibiting Cellular Specificity and Therapeutic Activity
Meike N. Leiske, Zihnil. A. I. Mazrad, Aykut Zelcak, Kanu Wahi, Thomas P. Davis, Joshua A. McCarroll, Jeff Holst and Kristian Kempe
Biomacromolecules, 2022, 23, 2374
DOI: 10.1021/acs.biomac.2c00143

Hetero‐Diels–Alder Cycloaddition with RAFT Polymers as Bioconjugation Platform
Ana Beloqui, Shivshankar R. Mane, Marcel Langer, Mathias Glassner, Dennis M. Bauer, Ljiljana Fruk, Christopher Barner‐Kowollik and Guillaume Delaittre
Angew Chem Int Ed, 2020, 59, 19951
DOI: 10.1002/anie.202005747

Bioactive mesoglobules of poly(di(ethylene glycol) monomethyl ether methacrylate)–peptide conjugate
Roza Trzcinska, Dawid Szweda, Stanislav Rangelov, Piotr Suder, Jerzy Silberring, Andrzej Dworak and Barbara Trzebicka
J. Polym. Sci. A Polym. Chem., 2012, 50, 3104
DOI: 10.1002/pola.26097

Aqueous solution behavior of comb‐shaped poly(2‐ethyl‐2‐oxazoline)
Christine Weber, Sarah Rogers, Antje Vollrath, Stephanie Hoeppener, Tobias Rudolph, Nicole Fritz, Richard Hoogenboom and Ulrich S. Schubert
J. Polym. Sci. A Polym. Chem., 2013, 51, 139
DOI: 10.1002/pola.26332

A Sugar Decorated Macromolecular Bottle Brush by Carbohydrate-Initiated Cationic Ring-Opening Polymerization
Christine Weber, Justyna A. Czaplewska, Anja Baumgaertel, Esra Altuntas, Michael Gottschaldt, Richard Hoogenboom and Ulrich S. Schubert
Macromolecules, 2012, 45, 46
DOI: 10.1021/ma202401x

A Polymer Prodrug Strategy to Switch from Intravenous to Subcutaneous Cancer Therapy for Irritant/Vesicant Drugs
Alexandre Bordat, Tanguy Boissenot, Nada Ibrahim, Marianne Ferrere, Manon Levêque, Léa Potiron, Stéphanie Denis, Sébastien Garcia-Argote, Olivia Carvalho, Jérôme Abadie, Catherine Cailleau, Grégory Pieters, Nicolas Tsapis and Julien Nicolas
J. Am. Chem. Soc., 2022, 144, 18844
DOI: 10.1021/jacs.2c04944

POx as an Alternative to PEG? A Hydrodynamic and Light Scattering Study
Mandy Grube, Meike N. Leiske, Ulrich S. Schubert and Ivo Nischang
Macromolecules, 2018, 51, 1905
DOI: 10.1021/acs.macromol.7b02665

Well-Defined Aminooxy Terminated N-(2-Hydroxypropyl) Methacrylamide Macromers for Site Specific Bioconjugation of Glycoproteins
Pradeep K. Dhal, Steven C. Polomoscanik, Diego A. Gianolio, Patrick G. Starremans, Michelle Busch, Kim Alving, Bo Chen and Robert J. Miller
Bioconjugate Chem., 2013, 24, 865
DOI: 10.1021/bc300472e

Protein PEPylation: A New Paradigm of Protein–Polymer Conjugation
Yingqin Hou and Hua Lu
Bioconjugate Chem., 2019, 30, 1604
DOI: 10.1021/acs.bioconjchem.9b00236

Unravelling Heterogeneities in Complement and Antibody Opsonization of Individual Liposomes as a Function of Surface Architecture
Rasmus Münter, Camilla Stavnsbjerg, Esben Christensen, Mikkel E. Thomsen, Allan Stensballe, Anders E. Hansen, Ladan Parhamifar, Kasper Kristensen, Jens B. Simonsen, Jannik B. Larsen and Thomas L. Andresen
Small, 2022, 18
DOI: 10.1002/smll.202106529

The Elusive Seven-Membered Cyclic Imino Ether Tetrahydrooxazepine
Bart Verbraeken, Jan Hullaert, Joachim van Guyse, Kristof Van Hecke, Johan Winne and Richard Hoogenboom
J. Am. Chem. Soc., 2018, 140, 17404
DOI: 10.1021/jacs.8b10918

Rare Earth Metal-Mediated Precision Polymerization of Vinylphosphonates and Conjugated Nitrogen-Containing Vinyl Monomers
Benedikt S. Soller, Stephan Salzinger and Bernhard Rieger
Chem. Rev., 2016, 116, 1993
DOI: 10.1021/acs.chemrev.5b00313

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li and Zhiyong Tang
Cancer Nexus, 2026
DOI: 10.1002/cnx2.70021

How To Tune the Gene Delivery and Biocompatibility of Poly(2-(4-aminobutyl)-2-oxazoline) by Self- and Coassembly
Meike N. Leiske, Fabian H. Sobotta, Friederike Richter, Stephanie Hoeppener, Johannes C. Brendel, Anja Traeger and Ulrich S. Schubert
Biomacromolecules, 2018, 19, 748
DOI: 10.1021/acs.biomac.7b01535

Reversible Bioconjugation: Biodegradable Poly(phosphate)‐Protein Conjugates
Tobias Steinbach, Greta Becker, Alina Spiegel, Tamiris Figueiredo, Daniela Russo and Frederik R. Wurm
Macromolecular Bioscience, 2017, 17
DOI: 10.1002/mabi.201600377

Therapeutic potential of polypeptide-based conjugates: Rational design and analytical tools that can boost clinical translation
Tetiana Melnyk, Snežana Đorđević, Inmaculada Conejos-Sánchez and María J. Vicent
Advanced Drug Delivery Reviews, 2020, 160, 136
DOI: 10.1016/j.addr.2020.10.007

Poly(2‐Hydroxymethyl‐2‐Oxazoline) as Super‐Hydrophilic Antifouling Polymer
Somdeb Jana, Milan Roels, Meike N. Leiske, Yann Bernhard, Bruno G. De Geest., Kristof Van Hecke and Richard Hoogenboom
Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202424873

Polymerization of N-Substituted Glycine N-Thiocarboxyanhydride through Regioselective Initiation of Cysteamine: A Direct Way toward Thiol-Capped Polypeptoids
Xinfeng Tao, Botuo Zheng, Tianwen Bai, Min-Hui Li and Jun Ling
Macromolecules, 2018, 51, 4494
DOI: 10.1021/acs.macromol.8b00259

Tunable degradation of polyethylene glycol‐like polymers based on imine and oxime bonds
Joe Collins, Zeyun Xiao and Luke A. Connal
J. Polym. Sci. Part A: Polym. Chem., 2017, 55, 3826
DOI: 10.1002/pola.28856

Cylindrical Brush Polymers with Polysarcosine Side Chains: A Novel Biocompatible Carrier for Biomedical Applications
Christian Hörtz, Alexander Birke, Leonard Kaps, Sandra Decker, Eva Wächtersbach, Karl Fischer, Detlef Schuppan, Matthias Barz and Manfred Schmidt
Macromolecules, 2015, 48, 2074
DOI: 10.1021/ma502497x

Subcutaneous drug delivery from nanoscale systems
Lorenzo Tomasini, Marianne Ferrere and Julien Nicolas
Nat Rev Bioeng, 2024, 2, 501
DOI: 10.1038/s44222-024-00161-w

Synthesis and Investigation of Chiral Poly(2,4-disubstituted-2-oxazoline)-Based Triblock Copolymers, Their Self-Assembly, and Formulation with Chiral and Achiral Drugs
Mengshi Yang, Malik Salman Haider, Stefan Forster, Chen Hu and Robert Luxenhofer
Macromolecules, 2022, 55, 6176
DOI: 10.1021/acs.macromol.2c00229

Synthesis and Characterization of Stimuli‐Responsive Star‐Like Polypept(o)ides: Introducing Biodegradable PeptoStars
Regina Holm, Benjamin Weber, Philipp Heller, Kristina Klinker, Dana Westmeier, Dominic Docter, Roland H. Stauber and Matthias Barz
Macromolecular Bioscience, 2017, 17
DOI: 10.1002/mabi.201600514

Protein‐Polymer Bioconjugates Prepared by Post‐Polymerization Modification of Alternating Copolymers
Samantha Saxer, Omer Erdogan, Cédric Paniagua, Alain Chavanieu, Xavier Garric and Vincent Darcos
Eur J Org Chem, 2022, 2022
DOI: 10.1002/ejoc.202100576

Biodegradable Polysarcosine with Inserted Alanine Residues: Synthesis and Enzymolysis
Peng Zhou, Tianlun Shen, Wanli Chen, Jihong Sun and Jun Ling
Biomacromolecules, 2022, 23, 1757
DOI: 10.1021/acs.biomac.2c00001

Low Fouling Polysulfobetaines with Variable Hydrophobic Content
Lisa Schardt, Alejandro Martínez Guajardo, Julian Koc, Jessica L. Clarke, John A. Finlay, Anthony S. Clare, Harrison Gardner, Geoffrey W. Swain, Kelli Hunsucker, André Laschewsky and Axel Rosenhahn
Macromol. Rapid Commun., 2022, 43
DOI: 10.1002/marc.202100589

Controlled synthesis of polypeptides
Yang Liu, Di Li, Jianxun Ding and Xuesi Chen
Chinese Chemical Letters, 2020, 31, 3001
DOI: 10.1016/j.cclet.2020.04.029