Issue 27, 2024

Tuneable redox-responsive albumin-hitchhiking drug delivery to tumours for cancer treatment

Abstract

This paper outlines a novel drug delivery system for highly cytotoxic mertansine (DM1) by conjugating to an albumin-binding Evans blue (EB) moiety through a tuneable responsive disulfide linker, providing valuable insights for the development of effective drug delivery systems toward cancer therapy.

Graphical abstract: Tuneable redox-responsive albumin-hitchhiking drug delivery to tumours for cancer treatment

Supplementary files

Article information

Article type
Communication
Submitted
06 4 2024
Accepted
11 6 2024
First published
20 6 2024
This article is Open Access
Creative Commons BY-NC license

J. Mater. Chem. B, 2024,12, 6563-6569

Tuneable redox-responsive albumin-hitchhiking drug delivery to tumours for cancer treatment

S. Fu, A. Zheng, L. Wang, J. Chen, B. Zhao, X. Zhang, V. A. A. McKenzie, Z. Yang, R. M. Leblanc, R. Prabhakar and F. Zhang, J. Mater. Chem. B, 2024, 12, 6563 DOI: 10.1039/D4TB00751D

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