Issue 47, 2021

An alginate-confined peroxygenase-CLEA for styrene epoxidation

Abstract

Oxyfunctionalisation reactions in neat substrate still pose a challenge for biocatalysis. Here, we report an alginate-confined peroxygenase-CLEA to catalyse the enantioselective epoxidation of cis-β-methylstyrene in a solvent-free reaction system achieving turnover numbers of 96 000 for the biocatalyst and epoxide concentrations of 48 mM.

Graphical abstract: An alginate-confined peroxygenase-CLEA for styrene epoxidation

Supplementary files

Article information

Article type
Communication
Submitted
08 4 2021
Accepted
07 5 2021
First published
07 5 2021
This article is Open Access
Creative Commons BY license

Chem. Commun., 2021,57, 5766-5769

An alginate-confined peroxygenase-CLEA for styrene epoxidation

F. E. H. Nintzel, Y. Wu, M. Planchestainer, M. Held, M. Alcalde and F. Hollmann, Chem. Commun., 2021, 57, 5766 DOI: 10.1039/D1CC01868J

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements