Issue 24, 2016

Decorated self-assembling β3-tripeptide foldamers form cell adhesive scaffolds

Abstract

A popular strategy to control cellular growth and differentiation is the employment of self-assembling peptides as biomaterials. In this study we decorated ultrashort helical N-acetylated β-tripeptides with cell adhesion signals IKVAV and RGD, which spontaneously self-assemble to give nanofibres with multiple signals, and form a bioscaffold that supports the growth of cells.

Graphical abstract: Decorated self-assembling β3-tripeptide foldamers form cell adhesive scaffolds

  • This article is part of the themed collection: Foldamers

Supplementary files

Article information

Article type
Communication
Submitted
11 1 2016
Accepted
29 2 2016
First published
29 2 2016

Chem. Commun., 2016,52, 4549-4552

Decorated self-assembling β3-tripeptide foldamers form cell adhesive scaffolds

K. Luder, K. Kulkarni, H. W. Lee, R. E. Widdop, M. P. Del Borgo and M. Aguilar, Chem. Commun., 2016, 52, 4549 DOI: 10.1039/C6CC00247A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements