Issue 17, 2016

Boronic acids for fluorescence imaging of carbohydrates

Abstract

“Fluorescence imaging” is a particularly exciting and rapidly developing area of research; the annual number of publications in the area has increased ten-fold over the last decade. The rapid increase of interest in fluorescence imaging will necessitate the development of an increasing number of molecular receptors and binding agents in order to meet the demand in this rapidly expanding area. Carbohydrate biomarkers are particularly important targets for fluorescence imaging given their pivotal role in numerous important biological events, including the development and progression of many diseases. Therefore, the development of new fluorescent receptors and binding agents for carbohydrates is and will be increasing in demand. This review highlights the development of fluorescence imaging agents based on boronic acids a particularly promising class of receptors given their strong and selective binding with carbohydrates in aqueous media.

Graphical abstract: Boronic acids for fluorescence imaging of carbohydrates

Article information

Article type
Feature Article
Submitted
17 10 2015
Accepted
23 11 2015
First published
23 11 2015
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 3456-3469

Boronic acids for fluorescence imaging of carbohydrates

X. Sun, W. Zhai, J. S. Fossey and T. D. James, Chem. Commun., 2016, 52, 3456 DOI: 10.1039/C5CC08633G

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements