Jiaqi He, Chunguang Zhang, Chao Liang, Wenchi Xue, Yongheng Li, Lili Dai, Chunyuan Liu, Wan-Ru Zhuang, Xianbin Ma, Ran Cheng, Yao Lei, Weidong Nie and Hai-Yan Xie

Cell Reports Medicine, 2025, 6, 102510
DOI: 10.1016/j.xcrm.2025.102510

Deciphering endogenous CD8+ T cell interactions using an engineered sortase A system

Jiaqi He, Chunguang Zhang, Xin-He Yu, Wan-Ru Zhuang, Chao Liang, Wenchi Xue, Wanting Zhang, Yao Lei, Weidong Nie and Hai-Yan Xie

Cell Biomaterials, 2026, 100454
DOI: 10.1016/j.celbio.2026.100454

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen and Hong Chen

Advanced Science, 2026, 13
DOI: 10.1002/advs.202505387

A smart polymer-based nanoplatform potentiates cancer ferroptosis-immunotherapy via perturbing metabolic compensation

Yongjuan Li, Mengzhe Zhang, Xiao Weng, Yichen Guo, Guodong Zhao, Yayun Wang, Xinxin Wang, Jinjie Zhang, Rong Ma, Xiaocao Gong, Xiaoyuan Chen and Weijing Yang

Journal of Controlled Release, 2026, 395, 115001
DOI: 10.1016/j.jconrel.2026.115001

In vivo magnetic resonance imaging of glucose via interfacial enzyme-catalyzed signal-amplifying probes

Weitao Yang, Zhuoyao Wu, Ruizhuo Ouyang, Chenyu Dai, Yan Xu, Hui Wang, Gongyao Yu, Panpan Zhu, Dinghua Liu, Yanjing Yun, Youyi Yu and Bingbo Zhang

Cell Biomaterials, 2026, 100367
DOI: 10.1016/j.celbio.2026.100367

Mitochondria-localized photocatalyst of biomimetic organic semiconductor nanoparticles for NIR-activatable photocatalytic immunotherapy

Yu Wang, Yijian Gao, Yuliang Yang, Jie Zhang, Yingpeng Wan, Xiliang Li, Ning Li, Guangtao Fu, Yuhui Yang, Zeng Li, Qi Zhao, Yuanfeng Chen and Shengliang Li

Sci. Adv., 2025, 11
DOI: 10.1126/sciadv.adx4850

Advances in Nanotechnology‐Enabled Optical Biosensors for Dengue Virus Detection: A Systematic Review

Marta Quero‐Delgado, Helena Codina, Rafael Gómez, Francisco José Terán, M. A. Muñoz‐Fernández, José Luis Jiménez, Salvador Resino, Daniel Sepúlveda‐Crespo and Isidoro Martínez

Medicinal Research Reviews, 2026, 46, 70
DOI: 10.1002/med.70006

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

Na Hang, Runkang Zhao, Fan Zhang, Dandan Guo, Qing Li, Zhijun Shen, Ruiqing Gao, Chenyu Gao, Zhao Xie, Sentao Fu, Peng Luo, Bufu Tang and Ling Wang

MedComm, 2026, 7
DOI: 10.1002/mco2.70749

Metabolic Reprogramming of Tumors: Induced Immunosuppression and Therapeutic Prospects of Nanoscale Drug Delivery Systems

Qianwen Li, Fansu Meng, Lina Yang, Alicia Marcelina Díaz García, Marina Parkhats, Jaiwoo Lee, Kosuke Kusamori, Makiya Nishikawa, Honghui Gu, Qi Li, Gareth R. Williams, Zhenjiang Yang and Yu Cai

Mol. Pharmaceutics, 2025, 22, 5193
DOI: 10.1021/acs.molpharmaceut.5c00342

A UHPLC-Orbitrap-MS Metabolomics Strategy Reveals Glycerophospholipid Metabolic Remodeling Is Associated with the Anti-Arthritic Effect of Glycyrrhiza Protein–Paeoniflorin Nanoparticles via PI3K/AKT/NLRP3 Axis

Na Zhang, Xiaoyun Yang, Cui Li, Miaoxin Huo, Yuan Gao, Dong Bai and Yuqin Yang

Molecules, 2026, 31, 554
DOI: 10.3390/molecules31030554

Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy

Yifei Jiang, Huizhen Yang, Guoping Jia, Wangxi Hai, Rongyi Huang, Peng Wang, Min Zhang, Danni Li, Yizhou Chen, Xiao Li, Biao Li and Chunfu Zhang

Exploration, 2026, 6
DOI: 10.1002/exp2.70144

Close and Enhance the Cancer‐Immunity Cycle by Engineered Dual‐Targeted Nano‐Adaptors

Pengkai Wu, Ziqu Fang, Longhui Wang, Yong Zhu, Weiwei Long, Mingshan Wang, Zhihao Sun, Zulipikaer Wusiman, Qiang Wang, Kaikai Wang, Dan Ding, Dengqiu Xu and Beicheng Sun

Advanced Materials, 2026, 38
DOI: 10.1002/adma.202521444

Nanomaterials-Guided Metabolism–Immunity Crosstalk for Boosting Cancer Immunotherapy

Yongjuan Li, Nannan Sun, Yichen Guo, Xiao Weng, Yayun Wang, Mengzhe Zhang, Rong Ma, Sheng Wang, Fenghua Meng and Weijing Yang

Biomacromolecules, 2026
DOI: 10.1021/acs.biomac.6c00312

Biomimetic Nanoparticles for Targeted Lung Cancer Immunotherapy via Specific Clearance of High Potassium

Jiaqi You, Jie Shen, Wenwen Liu, Juan Zhou, Yimin Yu, Chengyu Liu, Feng Wang, Ang Li and Jianou Qiao

ACS Appl. Nano Mater., 2025, 8, 3787
DOI: 10.1021/acsanm.4c06240

Immune inflammation and metabolic interactions in the pathogenesis of diabetic nephropathy

Guangjian Hou, Youzi Dong, Yuehua Jiang, Wenbo Zhao, Le Zhou, Shengnan Cao and Wei Li

Front. Endocrinol., 2025, 16
DOI: 10.3389/fendo.2025.1602594

Targeted ROS Scavenging for Disease Therapies Using Nanomaterials

Yajie Zhang, Ye Zhang, Ruizheng Liang, Jianhua Zou, Renjun Pei and Xiaoyuan Chen

Advanced Materials, 2025, 37
DOI: 10.1002/adma.202504435

Nanomedicine-mediated modulation of tumor metabolism for enhanced immunotherapy

Yanjun Liu, Dongqi Sun, Wenshi Li, Zhixiao Zhang, Ce Li, Xiaofang Che and Shenwu Zhang

Journal of Controlled Release, 2026, 390, 114587
DOI: 10.1016/j.jconrel.2025.114587

Highly Active Strontium Peroxide Nanoparticles Induce Alkalization/Oxidation to Potentiate Cancer Immuno-Metabolic Therapy

Qiu-Yi Duan, Liying Wang, Xi Cheng, Shuwen Qiu, Yuemei Wang, Dongliang Huo, Jiadie Yu, Chang Liu, Minfeng Huo and Jianlin Shi

ACS Nano, 2026, 20, 3030
DOI: 10.1021/acsnano.5c19350

Breaking Glycolysis Barriers to Immunotherapy with Nanomedicines

Miya Zhang, Yanhong Ren, Jiaping Li, Jiaji Yu, Qianqi Li, Heng Zhao, Zheng Wang, Xiaoyuan Chen and Junjie Cheng

ACS Nano Med., 2026, 1, 149
DOI: 10.1021/acsnanomed.5c00042

Nanomedicines Reshape the Tumor Microenvironment: Multidimensional Strategies from Modulating “Barriers” to Metabolic Intervention

Xinming Zhao, Dequan Liu, Guandu Li, Wenfei Xu and Guangzhen Wu

IJN, 2026, Volume 21, 1
DOI: 10.2147/IJN.S570411

Black phosphorus-based nanomedicines

Yijie Fan, Liyuan Chen, Jingning Zhang, Cong Liu, Linsu Liu, Ruizeng Luo, Shiwang Xie, Zhou Li, Yan Liu and Dan Luo

Matter, 2026, 9, 102634
DOI: 10.1016/j.matt.2025.102634

A Bone Marrow-Targeted Nanomodulator as a Histone Lactylation Inhibitor for Reversing Immune Tolerance in Multiple Myeloma

Wei Wu, Cheng-Ling Zhang, Yu-Ling Yang, Li Gao, Yunjing Zeng, Zhong Luo, Xue Dong, Xi Zhang and Xiaoyuan Chen

ACS Nano, 2026, 20, 12918
DOI: 10.1021/acsnano.5c21396

Metabolic Inhibitor Loaded Metal–Phenolic Nanocapsules Enable Synergistic Cancer Therapy through Cuproptosis and Immunometabolic Reprogramming

Bin Li, Houyang Hu, Songyan Li, Xuechun Wang, Zilin Ma, Wen Zhao, Yunxuan Song, Jianwei Jiao, Fenglei Xu, Xiuying Duan and Guiqiang Zhang

ACS Appl. Mater. Interfaces, 2025, 17, 51659
DOI: 10.1021/acsami.5c10711

Turning cold tumors into hot tumors to ignite immunotherapy

Yuan-Tong Liu, Yun-Long Wang, Shuo Wang, Jia-Jun Li, Wei He, Xin-Juan Fan and Xiang-Bo Wan

Mol Cancer, 2025, 24
DOI: 10.1186/s12943-025-02477-6

Porosity Engineering of MXene Architectures: Toward High‐Performance Aqueous Electrochemical Energy Storage

Shude Liu, Jieming Chen, Xue Peng, Huilin Zhang, Ling Kang, Ming Ma, Zhaoling Li, Yusuke Yamauchi and Bin Ding

Advanced Materials, 2026
DOI: 10.1002/adma.202515392

Tumor-Associated Macrophages: Polarization, Immunoregulation, and Immunotherapy

Abdullah Farhan Saeed

Cells, 2025, 14, 741
DOI: 10.3390/cells14100741

Oxamate Nanoparticles for Enhanced Tumor Immunotherapy through Blocking Glycolysis Metabolism and Inducing Pyroptosis

Kuo He, Binbin Ding, Jing Li, Qi Meng, Hao Chen, Ziyao Li, Jiashi Zhang, Xinyu Ma, Junhao Shao, Ping’an Ma and Jun Lin

Nano Lett., 2025, 25, 10053
DOI: 10.1021/acs.nanolett.5c01811

Lymphocyte‐Mimicking Sonosensitizers Boost Cancer Immunotherapy via Sequential Ultrasound Activation

Jiawei Zhu, Xiaorui Wang, Runtao Li, Tian Zhang, Lei An, Xuejiao Song, Xiaochen Dong and Yu Cai

Adv Funct Materials, 2025, 35
DOI: 10.1002/adfm.202509057

Cyclodextrin-based nanotherapeutics: A promising strategy for enhanced cancer therapy

Menglin Zhang, Fanpeng Ran, Yun Zhang, Xiaoli Zhang, Zhigang Xu and Xiaoxiao Shi

Chinese Chemical Letters, 2026, 37, 111232
DOI: 10.1016/j.cclet.2025.111232

Intranasal hybrid vesicles delivering personalized in situ nano-vaccines induce glioblastoma remodeling to sensitize immunotherapy

Xue Wang, Hanwen Zhang, Mingzhi Han, Fucai Chen, Yingjie Zhang, Kuanhan Feng, Jinghuang Wang, Yali Shi, Peng Cao, Liuqing Di and Ruoning Wang

Nano Today, 2025, 65, 102840
DOI: 10.1016/j.nantod.2025.102840

Nanovaccines: Antigen selection, stabilization, adjuvantation, formulation, and evaluation

Lisen Lu, Muyang Yang, Deqiang Deng, Xiujuan Shi, Jonathan F. Lovell and Honglin Jin

Coordination Chemistry Reviews, 2025, 541, 216806
DOI: 10.1016/j.ccr.2025.216806

Redirecting Tryptophan Metabolism Through Host‐Microbial Crosstalk to Enhance Precise Bioorthogonal Chemoimmunotherapy

Yue Sun, Congcong Huang, Chenglong Ma, Chuanqi Zhao, Mengmeng Liu, Zitong Zhu, Yanjie Zhang, Jinsong Ren and Xiaogang Qu

Advanced Materials, 2026, 38
DOI: 10.1002/adma.202517934

Emerging nano-immunotherapeutic strategies achieve metastatic colorectal cancer precision therapy

Songsong Jiang, Ziheng Zhang, Yongfei Mao, Xiangwei Xia, Jing Luo, Yang Zhang and Yihang Yuan

J Nanobiotechnol, 2026, 24
DOI: 10.1186/s12951-025-03933-7

A hypoxia-activated copper ion nanoexchanger for cancer immunotherapy by in situ precise production of immunogenic cell death inducer

Xinlu Zhang, Yongxin Liu, Huan Li, Shutong Chen, Guocheng Wang, Xu Zhang, Chen Cao, Xiaoyuan Chen and Sheng Wang

Chinese Chemical Letters, 2026, 37, 111404
DOI: 10.1016/j.cclet.2025.111404

Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li and Hao Yu

Int J Mol Med, 2025, 57, 1
DOI: 10.3892/ijmm.2025.5712

Tumor Microenvironment Metabolism‐Modulating Nanomedicines for Enhancing Anti‐Tumor Immunity

Jiajie Chen, Simiao Fei, Zhihao Cao, Xinchun Liu, Weizhi Ji, Hangrong Chen, Yuyu Niu and Zebin Yang

Small, 2025, 21
DOI: 10.1002/smll.202509685

MOF-based nanozymes: Rational design and biomedical applications

Rui Chen, Ying Bao, Rong Huang, Huan Liu, Yang Luo and Dinglin Zhang

Biomaterials, 2026, 333, 124201
DOI: 10.1016/j.biomaterials.2026.124201

Ultrasound-activated miR-195-5p/shikonin nanobubbles remodel immunosuppressive microenvironment via immunogenic cell death to potentiate PD-1/PD-L1 blockade in hepatocellular carcinoma

Yandi Tan, Qiao Xu, Yezi Chen, Yun Liu, Chaoqi Liu, Xinwu Cui and Yun Zhao

Materials Today Bio, 2025, 34, 102216
DOI: 10.1016/j.mtbio.2025.102216

Self‐Trapped Excitons in Carbon Quantum Dots with Large NIR‐II Photo‐Thermoelectric Catalysis Induce Pyroptosis for Cancer Therapy

Tesen Zhang, Qingcheng Wang, Quansheng Cheng, Han Wang, He Feng, Hui Zhang, Mengbo Lin, Feili Cai, Zheng Fang, Ruo Wang and Gang Chen

Advanced Science, 2026, 13
DOI: 10.1002/advs.202514249

Piezodynamic Therapy: Unleashing Mechanical Energy and Featuristic Next Generation Therapeutic Paradigms for Glioblastoma

Sibtain Muhammad, Madappa C. Maridevaru, Shubham Roy, Dongxiang Chen, Wenjun Zeng, Longhu Sun, Yinghe Zhang and Bing Guo

ACS Nano, 2025, 19, 33008
DOI: 10.1021/acsnano.5c11629

Revolutionizing Breast Cancer Treatment: Harnessing Ehrlich Ascites Carcinoma Model, Cancer Metabolism, and Nanotechnology-Enhanced Chemotherapy for Improved Patient Outcomes

Amira T. Khattab, Mai M. El-Keey, Doha M. Beltagy and Maha M. Salem

Cell Biochem Biophys, 2025, 84, 341
DOI: 10.1007/s12013-025-01929-6

Next-generation supramolecular photosensitizers based on coordination-driven self-assembly for therapeutic applications

Chonglu Li, Junhua Zhang, Qiao Song, Yuting Wang, Yanping Liu, Jingxin Wang and Yao Sun

Acta Biomaterialia, 2026, 210, 549
DOI: 10.1016/j.actbio.2025.12.039

Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy

Xiaosu Zhou, Ruibing Deng, Zunde Liao, Xiaoyu Huang, Junting Huang, Hanlou Yang, Kam W. Leong and Yiling Zhong

Advanced Science, 2025, 12
DOI: 10.1002/advs.202510004

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli and Cécilia Ménard‐Moyon

Advanced Science, 2026
DOI: 10.1002/advs.202522864

Emerging nanodelivery systems for cuproptosis induction: design strategies and multidimensional regulatory mechanisms

Zhao Yang, Sun Qingquan, Sun Baoyuan, Fan Shiwang, Wang Yu, Mu Hongjie and Chu Yongchao

International Journal of Pharmaceutics, 2026, 690, 126547
DOI: 10.1016/j.ijpharm.2025.126547

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Qingfei Zhang, Gaizhen Kuang, Wenzhao Li and Yuanjin Zhao

Advanced Science, 2025, 12
DOI: 10.1002/advs.202504986

Turning Foe into Friend: Bridging Neutrophil Biological Characteristics and Neutrophil‐Based Oncolytic Nanotherapeutics

Sitong Chen, Tao Zhang, Lihang Qu, Shuwen Han, Mengchi Sun and Xi Yang

Adv Funct Materials, 2026, 36
DOI: 10.1002/adfm.202515201

Targeting Age-Associated Immune Senescence via Nanoparticle-Based Metabolic Reprogramming

Preethi Gopalakrishnan Nair, Unnikrishnan Babukuttan Sheela, Vishnu Vijay Vijayan, Susan E. Howlett, Pieter Cullis and Shashi Gujar

ACS Nano, 2026
DOI: 10.1021/acsnano.5c18638

T-Cell “Rejuvenation” Nanovaccine: Enhancing Immunological Memory and Antitumor Responses through Telomere Extension

Xiuping Cao, Tao Zeng, Shiyan Bai, Shiqing Li, Yana Liu, Liyang Fang, Xiao Fang, Qi Chen, Chunhua Lu and Huanghao Yang

J. Am. Chem. Soc., 2026, 148, 4706
DOI: 10.1021/jacs.5c21977

Cathepsin B-Ignited Nanorocket To Blast Tumor Lysosomes for TLR-Fortified Lysosomal Immunotherapy with Dual-Switchable Fluorescence/Magnetic Resonance Imaging

Yue Chen, Qinyi Chen, Yuanyuan Ma, Xinge Su, Cheng Zhang, Kejing Li, Meiyi Liang, Minghao Sun, Liyuan Zhang, Xihe Kuang, Teng Zhang, Junjie Zhang, Ran Yan, Shenghong Ju and Wenpei Fan

J. Am. Chem. Soc., 2025, 147, 24884
DOI: 10.1021/jacs.5c07105

Cell Membrane‐Targeted J‐Aggregation Strategy for Synergistic Immune Checkpoint Degradation and Immunogenic Pyroptosis to Augment Tumor Immunotherapy

Xiaona Xu, Hao Zhang, Yahui Cao, Weiqing Liu, Zihui Chen and Changhua Li

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202516014

Remodeling the Tumor Microenvironment: Targeted Metal-Based Nanomaterials for Precision Theranostics of Pancreatic Ductal Adenocarcinoma

Pingting Luo, Pengli Zhang, Fengzheng Tang, Manxiang Wu, Guozhu Yang, Liangchen Luo, Jie Lin, Xuehua Ma, Changyong Gao, Guohua Li, Tianxiang Chen, Aiguo Wu and Qiang Li

ACS Materials Lett., 2026
DOI: 10.1021/acsmaterialslett.5c01559

Construction of Diverse Calcium‐Based Nanomaterials through a Microemulsion Method for Pyroptosis‐Initiated Antitumor Immunotherapy

Jing Li, Binbin Ding, Pan Zheng, Qi Meng, Hao Chen, Jia Tan, Wenying Zhang, Xinyu Ma, Jiashi Zhang, Ping'an Ma and Jun Lin

Advanced Materials, 2026, 38
DOI: 10.1002/adma.202516225