From gut to skin: exploring the potential of natural products targeting microorganisms for atopic dermatitis treatment

Hang Zhao, Xin Ma, Jiankun Song, Jingsi Jiang, Xiaoya Fei, Yue Luo, Yi Ru, Ying Luo, Chunjie Gao, Le Kuai and Bin Li

Food Funct., 2023, 14, 7825
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Pharmacokinetic/pharmacodynamic profiles of baicalin against Mycoplasma gallisepticum in an in vivo infection model

Jiaxin Bao, Zhiyong Wu, Muhammad Ishfaq, Jian Wang, Yusong Miao, Dong Niu, Rui Li, Jichang Li and Chunli Chen

Poultry Science, 2021, 100, 101437
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circ0066187 promotes pulmonary fibrogenesis through targeting STAT3-mediated metabolism signal pathway

Bo Liu, Weili Liu, Hongbo Li, Nailiang Zhai, Changjun Lv, Xiaodong Song and Shuanying Yang

Cell. Mol. Life Sci., 2025, 82
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Exosomal miR-181a-5p reduce Mycoplasma gallisepticum (HS strain) infection in chicken by targeting PPM1B and activating the TLR2-mediated MyD88/NF-κB signaling pathway

Yingfei Sun, Yingjie Wang, Yabo Zhao, Mengyun Zou and Xiuli Peng

Molecular Immunology, 2021, 140, 144
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Polypharmacology-based approach for screening TCM against coinfection of Mycoplasma gallisepticum and Escherichia coli

Jiaxin Bao, Yuan Wang, Shun Wang, Dong Niu, Ze Wang, Rui Li, Yadan Zheng, Muhammad Ishfaq, Zhiyong Wu and Jichang Li

Front. Vet. Sci., 2022, 9
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Mycoplasma gallisepticum induced inflammation-mediated Th1/Th2 immune imbalance via JAK/STAT signaling pathway in chicken trachea: Involvement of respiratory microbiota

Yusong Miao, Dong Niu, Ze Wang, Jian Wang, Zhiyong Wu, Jiaxin Bao, Wanying Hu, Yuquan Guo, Rui Li, Muhammad Ishfaq and Jichang Li

Veterinary Microbiology, 2022, 265, 109330
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Effects of fermented brewer's spent grains on growth performance, intestinal development and liver metabolism in broilers

Yuanfeng Li, Mintao Dong, Yan Wang and Qi Liu

Journal of Agriculture and Food Research, 2025, 23, 102156
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Baicalin ameliorates Mycoplasma gallisepticum-induced inflammatory injury via inhibiting STIM1-regulated ceramide accumulation in DF-1 cells

Xueping Chen, Muhammad Ishfaq and Jian Wang

Poultry Science, 2023, 102, 102687
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Avian safety guardian: Luteolin restores Mycoplasma gallisepticum-induced immunocompromise to improve production performance via inhibiting the IL-17/NF-kB pathway

Tengfei Wang, Guangyang Jiang, Shan Lv, Yufei Xiao, Changyong Fan, Mengyun Zou, Yingjie Wang, Qiao Guo, Md. Ahsanul Kabir and Xiuli Peng

International Immunopharmacology, 2023, 124, 110946
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Baicalin Protects Broilers against Avian Coronavirus Infection via Regulating Respiratory Tract Microbiota and Amino Acid Metabolism

Haipeng Feng, Jingyan Zhang, Xuezhi Wang, Zhiting Guo, Lei Wang, Kang Zhang and Jianxi Li

IJMS, 2024, 25, 2109
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A multi-dimensional validation strategy of pharmacological effects of Radix Isatidis Mixtures against the co-infection of Mycoplasma gallisepticum and Escherichia coli in poultry

Xiaodi Jin, Jinhai Huo, Yecheng Yao, Rui Li, Mengqing Sun, Jichang Li and Zhiyong Wu

Poultry Science, 2025, 104, 104576
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Bacillus subtilis KC1 prevents Mycoplasma gallisepticum-induced lung injury by enhancing intestinal Bifidobacterium animalis and regulating indole metabolism in chickens

Xueping Chen, Muhammad Ishfaq, Fangyuan Hu, Qian Zheng, Xiang Hu, Jian Wang and Nairui Huo

Poultry Science, 2023, 102, 102824
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Extracellular Vesicles From Mycoplasma gallisepticum: Modulators of Macrophage Activation and Virulence

Yingjie Wang, Shiying Li, Tengfei Wang, Mengyun Zou and Xiuli Peng

The Journal of Infectious Diseases, 2024, 229, 1523
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Lactobacillus salivarius ameliorates Mycoplasma gallisepticum-induced inflammation via the JAK/STAT signaling pathway involving respiratory microbiota and metabolites

Kexin Wang, Yusong Miao, Weiqi Liu, Ishfaq Muhammad, Jiaxin Bao, Xiaodi Jin, Zhiyong Wu, Rui Li, Chunli Chen and Jichang Li

Poultry Science, 2024, 103, 103942
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Gut Microbiota and SCFAs Play Key Roles in QingFei Yin Recipe Anti-Streptococcal Pneumonia Effects

Xiaozhou Sun, Dandan Wang, Lina Wei, Lizhong Ding, Yinan Guo, Zhongtian Wang, Yibu Kong, Jingjing Yang, Liwei Sun and Liping Sun

Front. Cell. Infect. Microbiol., 2021, 11
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In vitro absorption and lipid-lowering activity of baicalin esters synthesized by whole-cell catalyzed esterification

Mengmeng Zhang, Xuan Xin, Guanglei Zhao, Yucong Zou and Xiao-Feng Li

Bioorganic Chemistry, 2022, 120, 105628
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Hydroxysafflor Yellow A modulation of metabolite networks and inhibition of JAK2/STAT1 pathway in sepsis

Bingbing Pan, Fengting Chen, Siyan Shen, Yu Jiang, Ying Yang, Jia Wang, Yanjuan Liu, Lai Wei, Jitong Liu, Gaoyin Kong, Xuan He and Bing Guo

Sci Rep, 2025, 15
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Probiotic cocktails accelerate baicalin metabolism in the ileum to modulate intestinal health in broiler chickens

Mingkun Gao, Chaoyong Liao, Jianyang Fu, Zhonghua Ning, Zengpeng Lv and Yuming Guo

J Animal Sci Biotechnol, 2024, 15
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Baicalin and lung diseases

Zeina W. Sharawi, Islam M. Ibrahim, Esraa K. Abd-alhameed, Hanan S. Althagafy, Fatima A. Jaber, Steve Harakeh and Emad H. M. Hassanein

Naunyn-Schmiedeberg's Arch Pharmacol, 2024, 397, 1405
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Pharmacological effects of baicalin in lung diseases

Duoning Wang and Yi Li

Front. Pharmacol., 2023, 14
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Amino acid profiling as a screening and prognostic biomarker in active tuberculosis patients

Yunmei Sun, Yunli Liao, Nating Xiong, Xing He, Huihua Zhang, Xiaomin Chen, Guohui Xiao, Zhaoqin Wang, Weiqiao Rao and Guoliang Zhang

Clinica Chimica Acta, 2023, 548, 117523
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Saikosaponin A alleviates depressive-like behavior induced by reserpine in mice by regulating gut microflora and inflammatory responses

Menglin Wang, Haojun Li, Wenjing Zhang, Li Zhang, Shun Wang, Miao Jia, Lu Jia, Yu Zhang, Haifei Gao, Xianwu Zhang, Zhaohui Yin and Peng Zhong

PLoS ONE, 2025, 20, e0311207
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Immune Evasion of Mycoplasma gallisepticum: An Overview

Yang Liu, Yongqiang Wang and Shijun J. Zheng

IJMS, 2024, 25, 2824
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Extracellular HMGB1 as Inflammatory Mediator in the Progression of Mycoplasma Gallisepticum Infection

Yingjie Wang, Lulu Wang, Fuli Hu, Mengyun Zou, Ronglong Luo, Yingfei Sun, Tengfei Wang, Qiao Guo and Xiuli Peng

Cells, 2022, 11, 2817
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Herbal medicine in the treatment of COVID-19 based on the gut–lung axis

Qiaoyu He, Yumeng Shi, Qian Tang, Hong Xing, Han Zhang, Mei Wang and Xiaopeng Chen

Acupuncture and Herbal Medicine, 2022, 2, 172
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Naringin dihydrochalcone alleviates sepsis-induced acute lung injury via improving gut microbial homeostasis and activating GPR18 receptor

Siqi He, Yuzhen Zhuo, Lingzhi Cui, Sijia Zhang, Zhengwei Tu, Mukuo Wang, Xinyue Lv, Lixiu Ge, Jianping Lin, Lei Yang and Ximo Wang

International Immunopharmacology, 2024, 137, 112418
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Dietary administration of Bacillus subtilis KC1 improves growth performance, immune response, heat stress tolerance, and disease resistance of broiler chickens

Jian Wang, Muhammad Ishfaq, Yusong Miao, Zhongyuan Liu, Mengting Hao, Changyu Wang, Jiaqi Wang and Xueping Chen

Poultry Science, 2022, 101, 101693
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Methylsulfonylmethane ameliorates inflammation via NF-κB and ERK/JNK-MAPK signaling pathway in chicken trachea and HD11 cells during Mycoplasma gallisepticum infection

Yusong Miao, Dong Niu, Ze Wang, Jian Wang, Zhiyong Wu, Jiaxin Bao, Xiaodi Jin, Rui Li, Muhammad Ishfaq and Jichang Li

Poultry Science, 2022, 101, 101706
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Intestinal microbiota analysis and network pharmacology reveal the mechanism by which Lianhua Qingwen capsule improves the immune function of mice infected with influenza A virus

Ping Xu, Zhu Yang, Shuangqiu Du, Zongyuan Hong and Shuzhi Zhong

Front. Microbiol., 2022, 13
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Interactions between gut microbiota and polyphenols: A mechanistic and metabolomic review

Hao Cheng, Dandan Zhang, Jing Wu, Juan Liu, Yaochuan Zhou, Yuzhu Tan, Wuwen Feng and Cheng Peng

Phytomedicine, 2023, 119, 154979
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Research progress on pharmacological effects and new dosage forms of baicalin

Minglong Bao, Yunfei Ma, Mei Liang, Xinyi Sun, Xianghong Ju, Yanhong Yong and Xiaoxi Liu

Veterinary Medicine & Sci, 2022, 8, 2773
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Baicalin ameliorates the gut barrier function and intestinal microbiota of broiler chickens

Shuangxiu Wan, Linzheng Wang, Zhili Hao, Lin Zhu, Xiaoxia Mao, Hongquan Li, Panpan Sun, Wei Yin, Kuohai Fan, Hailong Zhang, Beibei Li, Wansen Nie, Zongjie Li and Na Sun

ABBS, 2024
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Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis

Lei Li, Herong Cui, Yue Zhang, Wei Xie, Ying Lin, Yufei Guo, Tingxuan Huang, Bei Xue, Wenbo Guo, Zhenfeng Huang, Tian Man, Huiyong Yu, Zhiguang Zhai, Miao Cheng, Mingzhe Wang, Haimin Lei and Chengxiang Wang

Biomedicine & Pharmacotherapy, 2023, 162, 114660
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Modified Montmorillonite Improved Growth Performance of Broilers by Modulating Intestinal Microbiota and Enhancing Intestinal Barriers, Anti-Inflammatory Response, and Antioxidative Capacity

Qi Wang, Xiaoli Zhan, Baikui Wang, Fei Wang, Yuanhao Zhou, Shujie Xu, Xiang Li, Li Tang, Qian Jin, Weifen Li, Li Gong and Aikun Fu

Antioxidants, 2022, 11, 1799
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Christensenella minuta Alleviates Acetaminophen-Induced Hepatotoxicity by Regulating Phenylalanine Metabolism

Ting Yao, Liyun Fu, Youhe Wu and Lanjuan Li

Nutrients, 2024, 16, 2314
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Gut Microbiota Dysbiosis Aggravates Mycoplasma gallisepticum Colonization in the Chicken Lung

Jian Wang, Xueping Chen, Jichang Li and Muhammad Ishfaq

Front. Vet. Sci., 2021, 8
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Quercetin restores respiratory mucosal barrier dysfunction in Mycoplasma gallisepticum-infected chicks by enhancing Th2 immune response

Shun Wang, Liyang Guo, Fuhua Gu, Jiaxin Bao, Yuquan Guo, Yongjie Zhang, Ze Wang, Rui Li, Zhiyong Wu and Jichang Li

Phytomedicine, 2024, 133, 155953
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The Influence of Heat Stress on Chicken Immune System and Mitigation of Negative Impacts by Baicalin and Baicalein

Vladimir Zmrhal, Andrea Svoradova, Eva Venusova and Petr Slama

Animals, 2023, 13, 2564
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Necroptosis in Pneumonia: Therapeutic Strategies and Future Perspectives

Xiuzhen Mei, Yuchen Zhang, Shu Wang, Hui Wang, Rong Chen, Ke Ma, Yue Yang, Ping Jiang, Zhixin Feng, Chao Zhang and Zhenzhen Zhang

Viruses, 2024, 16, 94
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Divergent impacts on the gut microbiome and host metabolism induced by traditional Chinese Medicine with Cold or Hot properties in mice

Bingbing Li, Xin Tao, Lili Sheng, Yan Li, Ningning Zheng and Houkai Li

Chin Med, 2022, 17
DOI: 10.1186/s13020-022-00697-2

Biological effects of baicalin on the ovine mammary cells and regulatory mechanism study by transcriptomic analysis

Chunwei Wang, Liqiang Chen, Sijia Ma, Ruixue Bai, Quanzhong Xu, Rui Feng, Chao Bian, Liguo Zhang and Xiaohu Su

Genomics, 2025, 117, 111012
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