Self-contained microfluidic systems: a review

Mitchell Boyd-Moss, Sara Baratchi, Martina Di Venere and Khashayar Khoshmanesh

Lab Chip, 2016, 16, 3177
DOI: 10.1039/C6LC00712K

Correcting the effect of hematocrit in whole blood coagulation analysis on paper-based lateral flow device

Hua Li, Daewoo Han, Giovanni M. Pauletti, Michael A. Hegener and Andrew J. Steckl

Anal. Methods, 2018, 10, 2869
DOI: 10.1039/C8AY00192H

Designing and prototyping a novel biosensor based on a volumetric bar-chart chip for urea detection

Mahdi Samadi Khezri, Mohammad Reza Housaindokht and Mojtaba Firouzi

Lab Chip, 2024, 24, 2298
DOI: 10.1039/D3LC00730H

All-printed semiquantitative paper-based analytical devices relying on QR code array readout

Aya Katoh, Kento Maejima, Yuki Hiruta and Daniel Citterio

Analyst, 2020, 145, 6071
DOI: 10.1039/D0AN00955E

Microfluidic devices based on textile threads for analytical applications: state of the art and prospects

Deonir Agustini, Fábio Roberto Caetano, Reverson Fernandes Quero, José Alberto Fracassi da Silva, Márcio Fernando Bergamini, Luiz Humberto Marcolino-Junior and Dosil Pereira de Jesus

Anal. Methods, 2021, 13, 4830
DOI: 10.1039/D1AY01337H

Paper-based microfluidics for experimental design: screening masking agents for simultaneous determination of Mn(ii) and Co(ii)

Nathan A. Meredith, John Volckens and Charles S. Henry

Anal. Methods, 2017, 9, 534
DOI: 10.1039/C6AY02798A

Integrated paper-based microfluidic devices for point-of-care testing

Tian Tian, Yunpeng Bi, Xing Xu, Zhi Zhu and Chaoyong Yang

Anal. Methods, 2018, 10, 3567
DOI: 10.1039/C8AY00864G

A simple thermometer-based photothermometric assay for alkaline phosphatase activity based on target-induced nanoprobe generation

Honghong Rao, Huiyi Huang, Xinyuan Zhang, Xin Xue, Mingyue Luo, Haixia Liu and Zhonghua Xue

New J. Chem., 2020, 44, 17753
DOI: 10.1039/D0NJ03920A

“Dip-and-read” paper-based analytical devices using distance-based detection with color screening

Kentaro Yamada, Daniel Citterio and Charles S. Henry

Lab Chip, 2018, 18, 1485
DOI: 10.1039/C8LC00168E

Microfluidic platforms for DNA methylation analysis

Ryoji Kurita and Osamu Niwa

Lab Chip, 2016, 16, 3631
DOI: 10.1039/C6LC00829A

Design of Raman reporter-embedded magnetic/plasmonic hybrid nanostirrers for reliable microfluidic SERS biosensors

Bingfang Zou, Shiyun Lou, Jie Duan, Shaomin Zhou and Yongqiang Wang

Nanoscale, 2023, 15, 8424
DOI: 10.1039/D3NR00303E

Quantitative and equipment-free paper-based agglutination assay of bacterial cells

Mohammad Al-Tamimi, Shahed Altarawneh, Minas A. Mustafa, Mariam El-sallaq and Penelope Shihab

RSC Adv., 2024, 14, 20516
DOI: 10.1039/D4RA03001J

An on-chip valve-assisted microfluidic chip for quantitative and multiplexed detection of biomarkers

Binfeng Hu, Yong Liu, Jinqi Deng, Lei Mou and Xingyu Jiang

Anal. Methods, 2018, 10, 2470
DOI: 10.1039/C8AY00682B

A portable polymeric electrochromism-based visual biosensing device with distance readout

Xujing Feng, Lijun Ding, Yi Zou, Huadong Heng, Kezuo Di, Zhiying Shao, Nan Hao and Kun Wang

Chem. Commun., 2024, 60, 2200
DOI: 10.1039/D3CC06316J

Converting colour to length based on the coffee-ring effect for quantitative immunoassays using a ruler as readout

Dagan Zhang, Bingbing Gao, Yangtian Chen and Hong Liu

Lab Chip, 2018, 18, 271
DOI: 10.1039/C7LC01127J

Diagnosis of disease relevant nucleic acid biomarkers with off-the-shelf devices

Lijuan Qi and Yan Du

J. Mater. Chem. B, 2022, 10, 3959
DOI: 10.1039/D2TB00232A

The CRISPR–Cas toolbox for analytical and diagnostic assay development

Yanan Tang, Lu Gao, Wei Feng, Chen Guo, Qianfan Yang, Feng Li and X. Chris Le

Chem. Soc. Rev., 2021, 50, 11844
DOI: 10.1039/D1CS00098E

Traffic light type paper-based analytical device for intuitive and semi-quantitative naked-eye signal readout

Sera Ohta, Ryuya Hiraoka, Yuki Hiruta and Daniel Citterio

Lab Chip, 2022, 22, 717
DOI: 10.1039/D1LC01060C

Wettability alteration in a functional capillary tube for visual quantitative point of care testing

Yansheng Li, Xiangyu Jiao, Xin Du, Fang Wang, Qianhui Wei, Yongqiang Wen and Xueji Zhang

Analyst, 2018, 143, 3001
DOI: 10.1039/C8AN00735G

A distance-based paper sensor for the determination of chloride ions using silver nanoparticles

Kamonchanok Phoonsawat, Nalin Ratnarathorn, Charles S. Henry and Wijitar Dungchai

Analyst, 2018, 143, 3867
DOI: 10.1039/C8AN00670A

A paper/polymer hybrid CD-like microfluidic SpinChip integrated with DNA-functionalized graphene oxide nanosensors for multiplex qLAMP detection

Maowei Dou, Sharma T. Sanjay, Delfina C. Dominguez, Sihui Zhan and XiuJun Li

Chem. Commun., 2017, 53, 10886
DOI: 10.1039/C7CC03246C

Quantitative injection strip platform using water-soluble paper and magnet based on a lateral flow assay

Yewon Kwon, Dami Kim and Sanghyo Kim

Anal. Methods, 2023, 15, 4168
DOI: 10.1039/D3AY01021J

Portable visual quantitative detection of aflatoxin B1using a target-responsive hydrogel and a distance-readout microfluidic chip

Yanli Ma, Yu Mao, Di Huang, Zhe He, Jinmao Yan, Tian Tian, Yuanzhi Shi, Yanling Song, Xingrui Li, Zhi Zhu, Leiji Zhou and Chaoyong James Yang

Lab Chip, 2016, 16, 3097
DOI: 10.1039/C6LC00474A

Hand-powered centrifugal microfluidic platform inspired by the spinning top for sample-to-answer diagnostics of nucleic acids

Lu Zhang, Fei Tian, Chao Liu, Qiang Feng, Tingxuan Ma, Zishan Zhao, Tiejun Li, Xingyu Jiang and Jiashu Sun

Lab Chip, 2018, 18, 610
DOI: 10.1039/C7LC01234A

A new sequential dual flow lab-on-a-chip with a lyophilized one-component chemiluminescence substrate for high-sensitive microchannel lateral flow assay (mLFA)

Supreeth Setty, Heeyeong Jang, Jungyoup Han, Joo Youn Park, Nogi Park, Keun Seok Seo and Chong Ahn

Sens. Diagn., 2025, 4, 320
DOI: 10.1039/D4SD00352G

Double inner standard plot model of an electrophoresis titration chip for a portable and green assay of protein content in milk

Cunhuai Wang, Qiang Zhang, Xiaoping Liu, Guoqing Li, Hao Kong, Muhammad Idrees Khan, Hua Xiao, Yuxing Wang, Weiwen Liu and Chengxi Cao

Lab Chip, 2019, 19, 484
DOI: 10.1039/C8LC01015C

Sandwich-type aptamer-based biosensors for thrombin detection

Somayeh Sahraneshin Samani, Elham Sameiyan, Farideh Tabatabaei Yazdi, Sayed Ali Mortazavi, Mona Alibolandi, Mohammad Ramezani, Seyed Mohammad Taghdisi and Khalil Abnous

Anal. Methods, 2024, 16, 1985
DOI: 10.1039/D3AY02196C

Toward practical application of paper-based microfluidics for medical diagnostics: state-of-the-art and challenges

Kentaro Yamada, Hiroyuki Shibata, Koji Suzuki and Daniel Citterio

Lab Chip, 2017, 17, 1206
DOI: 10.1039/C6LC01577H

Hydraulic–electric analogy for design and operation of microfluidic systems

Zhenglin Li, Chao Liu and Jiashu Sun

Lab Chip, 2023, 23, 3311
DOI: 10.1039/D3LC00265A

Paper-based chemometer device for the estimation of α-amylase—a biomarker for pancreatitis

Bethuel Daurai and Manashjit Gogoi

RSC Adv., 2024, 14, 24365
DOI: 10.1039/D4RA03804E

Humidity-enhanced microfluidic plasma separation on Chinese Xuan-papers

Xianchang Wu, Shuqiang Min, Tonghuan Zhan, Yange Huang, Hui Niu and Bing Xu

Lab Chip, 2024, 24, 4379
DOI: 10.1039/D4LC00393D

The outputs of molecular sensors detectable by human senses

Maria S. Rubel, Tatiana Zemerova and Dmitry M. Kolpashchikov

Chem. Commun., 2025, 61, 3472
DOI: 10.1039/D4CC06384H

Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of l-lactate

Wenjuan Wang, Danrong Chen, Yujiao Cai, Zijing Liu, Hongfen Yang, Hongbin Xie, Jinquan Liu and Shengyuan Yang

Anal. Methods, 2024, 16, 2077
DOI: 10.1039/D4AY00041B

A distance-based capillary biosensor using wettability alteration

Yansheng Li, Xiujin Men, Guowei Gao, Ye Tian, Yongqiang Wen and Xueji Zhang

Lab Chip, 2021, 21, 719
DOI: 10.1039/D0LC01147A

Paper-based microfluidic devices for food adulterants: Cost-effective technological monitoring systems

Rohitraj Ray, Anusha Prabhu, Dinesh Prasad, Vijay kumar Garlapati, Tejraj M. Aminabhavi, Naresh Kumar Mani and Jesus Simal-Gandara

Food Chemistry, 2022, 390, 133173
DOI: 10.1016/j.foodchem.2022.133173

Nano-Structural Superwetting Surfaces for Highly Reliable On-Site Detection of Bisphenol A

Li Dai, Zhihao Liu, Hai Zhu, Yanyan Wang, Ying Shen, Lunche Wang, Yu Huang and Fan Xia

Anal. Chem., 2023, 95, 16263
DOI: 10.1021/acs.analchem.3c03109

ARM-microcontroller based portable nitrite electrochemical analyzer using cytochrome c reductase biofunctionalized onto screen printed carbon electrode

Paulraj Santharaman, Krishna Arun Venkatesh, Kanagavel Vairamani, Alby Robson Benjamin, Niroj K. Sethy, Kalpana Bhargava and Chandran Karunakaran

Biosensors and Bioelectronics, 2017, 90, 410
DOI: 10.1016/j.bios.2016.10.039

A fully integrated distance readout ELISA-Chip for point-of-care testing with sample-in-answer-out capability

Dan Liu, Xingrui Li, Junkai Zhou, Shibo Liu, Tian Tian, Yanling Song, Zhi Zhu, Leiji Zhou, Tianhai Ji and Chaoyong Yang

Biosensors and Bioelectronics, 2017, 96, 332
DOI: 10.1016/j.bios.2017.04.044

A review on sensing mechanisms and strategies for telomerase activity detection

Danni Wang, Wanyi Xue, Xiuyan Ren and Zhangrun Xu

TrAC Trends in Analytical Chemistry, 2021, 134, 116115
DOI: 10.1016/j.trac.2020.116115

Mechano‐Based Transductive Sensing for Wearable Healthcare

Ting Wang, Hui Yang, Dianpeng Qi, Zhiyuan Liu, Pingqiang Cai, Han Zhang and Xiaodong Chen

Small, 2018, 14
DOI: 10.1002/smll.201702933

Exosome aggregation mediated stop‐flow paper‐based portable device for rapid exosome quantification

Boonta Chutvirasakul, Nantana Nuchtavorn, Leena Suntornsuk and Yong Zeng

Electrophoresis, 2020, 41, 311
DOI: 10.1002/elps.201900323

Visual and quantitative detection of E. coli O157:H7 by coupling immunomagnetic separation and quantum dot-based paper strip

Zhaohui Qiao, Qiqi Cai, Yingchun Fu, Chunyang Lei and Wenge Yang

Anal Bioanal Chem, 2021, 413, 4417
DOI: 10.1007/s00216-021-03395-4

Developing a point-of-care System for Determination of Dopamine, Ascorbic and Uric Acids in Biological Fluids Using a Screen-Printed Electrode Modified by Three Dimensional Graphene/Carbon Nanotube Hybrid

Ali Farahani and Hassan Sereshti

International Journal of Electrochemical Science, 2019, 14, 6195
DOI: 10.20964/2019.07.47

Distance-based quantitative determination of pyrophosphate ions with a Haus-made microfluidic paper-based device using the metal–organic framework NH2-MIL-88 (Fe)

Lili Yuan, Yongkang Yan, Yiyue Tang, Xueer Huang, Jiajing Liao, Jianmei Zou, Jinfang Nie, Lang Zhang, Shan Liao and Yun Zhang

Microchemical Journal, 2024, 203, 110871
DOI: 10.1016/j.microc.2024.110871

Portable biosensing devices for point-of-care diagnostics: Recent developments and applications

Mohammad Zarei

TrAC Trends in Analytical Chemistry, 2017, 91, 26
DOI: 10.1016/j.trac.2017.04.001

Simple Way To Fabricate Novel Paper-Based Valves Using Plastic Comb Binding Spines

Jinglong Han, Anjin Qi, Junrui Zhou, Guan Wang, Bowei Li and Lingxin Chen

ACS Sens., 2018, 3, 1789
DOI: 10.1021/acssensors.8b00518

Engineering Strategies for Advancing Optical Signal Outputs in Smartphone‐Enabled Point‐of‐Care Diagnostics

Kexin Fan, Weiran Liu, Yuchen Miao, Zhen Li and Guozhen Liu

Advanced Intelligent Systems, 2023, 5
DOI: 10.1002/aisy.202200285

Smartphone-Based Fully Automated Optofluidic Device with Laser Irradiation-Induced Image Whitening

M. Jalal Uddin, Nabil H. Bhuiyan, Jun. H. Hong and Joon S. Shim

Anal. Chem., 2021, 93, 6394
DOI: 10.1021/acs.analchem.0c05387

Recent progress of microfluidic reactors for biomedical applications

Huanhuan Shi, Kaixuan Nie, Bo Dong, Mengqiu Long, Hui Xu and Zhengchun Liu

Chemical Engineering Journal, 2019, 361, 635
DOI: 10.1016/j.cej.2018.12.104

A versatile capillaric circuits microfluidic viscometer

Claude Meffan, Julian Menges, Daniel Mak, Fabian Dolamore, Conan Fee, Volker Nock and Renwick C.J. Dobson

Sensors and Actuators A: Physical, 2023, 359, 114497
DOI: 10.1016/j.sna.2023.114497

Protein Determination by Distance and Color Changing via PEG-Based Hydrogels

Yanawut MANMANA, Takuya KUBO and Koji OTSUKA

CHROMATOGRAPHY, 2023, 44, 27
DOI: 10.15583/jpchrom.2022.015

A dual-mode assay kit using a portable potentiostat connected to a smartphone via Bluetooth communication and a potential-power angle-based paper device susceptible for low-cost point-of-care testing of iodide and dopamine

Mina Fotouhi, Shahram Seidi, Yasaman Razeghi and Shahab Torfinezhad

Analytica Chimica Acta, 2024, 1287, 342127
DOI: 10.1016/j.aca.2023.342127

Development of an Integrated Biochip System Consisting of a Magnetic Particle Washing Station and a Markerless Volumetric Biochip

Ho Seon Choi, Yong-Ho Jang and Suk-Jung Choi

BioChip J, 2023, 17, 68
DOI: 10.1007/s13206-022-00084-x

Current and future prospects for nanotechnology in animal production

Emily K. Hill and Julang Li

J Animal Sci Biotechnol, 2017, 8
DOI: 10.1186/s40104-017-0157-5

Instrument-free argentometric determination of chloride via trapezoidal distance-based microfluidic paper devices

Mohammad Rahbar, Brett Paull and Mirek Macka

Analytica Chimica Acta, 2019, 1063, 1
DOI: 10.1016/j.aca.2019.02.048

Disposable Paper-Based Analytical Device for Visual Speciation Analysis of Ag(I) and Silver Nanoparticles (AgNPs)

Qinlei Liu, Yao Lin, Jing Xiong, Li Wu, Xiandeng Hou, Kailai Xu and Chengbin Zheng

Anal. Chem., 2019, 91, 3359
DOI: 10.1021/acs.analchem.8b04609

Distance-Based Fluorescent Immunosensor for Point-of-Care Test of Illegal Additives through the Gas-Producing Nanozyme

Guosheng Cui, Yongbin Huang, Haoran Shen, Aori Qileng, Weipeng Liu and Yingju Liu

Anal. Chem., 2024, 96, 18221
DOI: 10.1021/acs.analchem.4c04427

Multicolor and photothermal dual-mode assay of alkaline phosphatase based on the UV light-assisted etching of gold nanorods

Tianran Lin, Shendong Liu, Juanjuan Huang, Chunsuo Tian, Li Hou, Fanggui Ye and Shulin Zhao

Analytica Chimica Acta, 2021, 1181, 338926
DOI: 10.1016/j.aca.2021.338926

A visual cardiovascular biomarker detection strategy based on distance as readout by the coffee-ring effect on microfluidic paper

Xin Wang, Weiguang Zhang, Sen Wang, Wei Liu, NaiFeng Liu and Dagan Zhang

Biochemical Engineering Journal, 2021, 176, 108176
DOI: 10.1016/j.bej.2021.108176

Recent Advancements on Hydrodynamics and Mass Transfer Characteristics for CO2 Absorption in Microreactors

Mohsin Pasha, Saier Liu, Jin Zhang, Min Qiu and Yuanhai Su

Ind. Eng. Chem. Res., 2022, 61, 12249
DOI: 10.1021/acs.iecr.2c01982

Multiplexed instrument-free meningitis diagnosis on a polymer/paper hybrid microfluidic biochip

Maowei Dou, Sharma T. Sanjay, Delfina C. Dominguez, Peng Liu, Feng Xu and XiuJun Li

Biosensors and Bioelectronics, 2017, 87, 865
DOI: 10.1016/j.bios.2016.09.033

A Self‐Powered Minimalistic Glucometer: A Lean Approach to Sustainable Single‐Use Point‐of‐Care Devices

Irene Merino‐Jimenez, Anna Llorella, Marina Navarro‐Segarra, Jordi Agramunt, Anna Grandas, Shelley D. Minteer, Juan Pablo Esquivel and Neus Sabaté

Adv Materials Technologies, 2021, 6
DOI: 10.1002/admt.202001051

Smartphone-deployable and all-in-one machine vision for visual quantification analysis based on distance readout of electrophoresis titration biosensor

Zehua Guo, Yiren Cao, Youli Tian, Liuyin Fan, Weiwen Liu, Yixin Ma, Qiang Zhang and Chengxi Cao

Biosensors and Bioelectronics, 2025, 267, 116832
DOI: 10.1016/j.bios.2024.116832

Simply converting color signal readout into thermal signal readout for breaking the color resolution limitation of colorimetric sensor

Mingyue Luo, Xin Xue, Honghong Rao, Hongqiang Wang, Xiuhui Liu, Xibin Zhou, Zhonghua Xue and Xiaoquan Lu

Sensors and Actuators B: Chemical, 2020, 309, 127707
DOI: 10.1016/j.snb.2020.127707

A perspective on flexible sensors in developing diagnostic devices

Lili Wang, Kai Jiang and Guozhen Shen

Applied Physics Letters, 2021, 119
DOI: 10.1063/5.0057020

Distance-based detection in analytical flow devices: From gas detection tubes to microfluidic chips and microfluidic paper-based analytical devices

Nantana Nuchtavorn, Tomas Rypar, Lukas Nejdl, Marketa Vaculovicova and Mirek Macka

TrAC Trends in Analytical Chemistry, 2022, 150, 116581
DOI: 10.1016/j.trac.2022.116581

An all-in-a-syringe immunoassay using autoinjected visual distance readout for simple quantitative testing of cancer biomarkers

Cuili Li, Maojie Xiang, Jie Liu and Guanglei Fu

Sensors and Actuators B: Chemical, 2025, 441, 138002
DOI: 10.1016/j.snb.2025.138002

Integrating of analytical techniques with enzyme-mimicking nanomaterials for the fabrication of microfluidic systems for biomedical analysis

Sherzod Shukhratovich Abdullaev, Raed H Althomali, Ahmad Raza Khan, Hijran Sanaan Jabbar, Munther abosoda, Ali ihsan, Saurabh Aggarwal, Yasser Fakri Mustafa, Ibrahim Hammoud Khlewee and Abeer mhussan jabbar

Talanta, 2024, 273, 125896
DOI: 10.1016/j.talanta.2024.125896

In situ Raman enhancement strategy for highly sensitive and quantitative lateral flow assay

Haicong Shen, Eunyeong Song, Yang Wang, Lingyan Meng, Jing Dong, Bingqian Lin, Di Huang, Zhichao Guan, Chaoyong Yang and Zhi Zhu

Anal Bioanal Chem, 2022, 414, 507
DOI: 10.1007/s00216-021-03419-z

Tutorial: design and fabrication of nanoparticle-based lateral-flow immunoassays

Claudio Parolo, Amadeo Sena-Torralba, José Francisco Bergua, Enric Calucho, Celia Fuentes-Chust, Liming Hu, Lourdes Rivas, Ruslan Álvarez-Diduk, Emily P. Nguyen, Stefano Cinti, Daniel Quesada-González and Arben Merkoçi

Nat Protoc, 2020, 15, 3788
DOI: 10.1038/s41596-020-0357-x

Detection and analysis of moving reaction boundary-based electrophoresis distance using smartphone images

Xinqiao SONG, Zehua GUO, Weiwen LIU, Genhan ZHA, Liuyin FAN, Chengxi CAO and Qiang ZHANG

CJCSP, 2023, 41, 752
DOI: 10.3724/SP.J.1123.2023.06001

Battery-powered distance-based electrochemical sensor using a longitudinally-oriented silver band electrode

Mahadurage Sachintha Wijesinghe, Karen Batchelder, Dhanushka Wickramasinghe, Jung-Min Oh and Kwok-Fan Chow

Sensors and Actuators B: Chemical, 2020, 308, 127684
DOI: 10.1016/j.snb.2020.127684

Recent applications of paper‐based point‐of‐care devices for biomarker detection

Worapot Suntornsuk and Leena Suntornsuk

Electrophoresis, 2020, 41, 287
DOI: 10.1002/elps.201900258

Development of a morphological color image processing algorithm for paper-based analytical devices

Vahid Hamedpour, Paolo Oliveri, Cristina Malegori and Tsuyoshi Minami

Sensors and Actuators B: Chemical, 2020, 322, 128571
DOI: 10.1016/j.snb.2020.128571

Paper-Based DNA Reader for Visualized Quantification of Soil-Transmitted Helminth Infections

Alex Guan Wang, Tianyu Dong, Hayam Mansour, Gabriela Matamoros, Ana L. Sanchez and Feng Li

ACS Sens., 2018, 3, 205
DOI: 10.1021/acssensors.7b00857

Afi-Chip: An Equipment-Free, Low-Cost, and Universal Binding Ligand Affinity Evaluation Platform

Yanling Song, Yuanzhi Shi, Xingrui Li, Yanli Ma, Mingxuan Gao, Dan Liu, Yu Mao, Zhi Zhu, Hui Lin and Chaoyong Yang

Anal. Chem., 2016, 88, 8294
DOI: 10.1021/acs.analchem.6b02140

Visual detection of chiral arginine enantiomer based on Fabry-Pérot resonator with BSA grafted polymer brush insulator as transducer

Weishun Zhu, Shunsheng Ye, Kewei Li, Jinqiu Lv, Fuqiang Fan, Liying Zhang, Xuemin Zhang, Yu Fu and Tieqiang Wang

Sensors and Actuators B: Chemical, 2024, 412, 135842
DOI: 10.1016/j.snb.2024.135842

Semi-quantitative visual detection of loop mediated isothermal amplification (LAMP)-generated DNA by distance-based measurement on a paper device

Irin Hongwarittorrn, Nuntaree Chaichanawongsaroj and Wanida Laiwattanapaisal

Talanta, 2017, 175, 135
DOI: 10.1016/j.talanta.2017.07.019

Biomarkers—A General Review

Jeffrey K. Aronson and Robin E. Ferner

CP Pharmacology, 2017, 76
DOI: 10.1002/cpph.19

An ITO-based point-of-care colorimetric immunosensor for ochratoxin A detection

Xiang Ren, Peng Lu, Rui Feng, Tong Zhang, Yong Zhang, Dan Wu and Qin Wei

Talanta, 2018, 188, 593
DOI: 10.1016/j.talanta.2018.06.004

Fabrication of microwell plates and microfluidic devices in polyester films using a cutting printer

Nikaele S. Moreira, Cyro L.S. Chagas, Karoliny A. Oliveira, Gerson F. Duarte-Junior, Fabrício R. de Souza, Murilo Santhiago, Carlos D. Garcia, Lauro T. Kubota and Wendell K.T. Coltro

Analytica Chimica Acta, 2020, 1119, 1
DOI: 10.1016/j.aca.2020.04.047

Compact common-path polarisation holographic microscope for measuring spatially-resolved Jones matrix parameters of dynamic samples in microfluidics

Gui-Xiang Chen, Ying-Ying Zhang, Yang Yang, Hong-Yi Huang, Qing-Yang Yue and Cheng-Shan Guo

Optics Communications, 2022, 503, 127460
DOI: 10.1016/j.optcom.2021.127460

Development of a wireless passive capacitively coupled contactless conductivity detection (WPC4D) for fluidic flow detection utilizing 3D printing and PCB technologies

Bao-Anh Hoang, Van-Anh Bui, Kien Do Trung, Hang Bui Thu, Trinh Chu Duc, Tung Thanh Bui and Loc Do Quang

Instrumentation Science & Technology, 2023, 51, 591
DOI: 10.1080/10739149.2023.2182791

A chromogenic reaction-free distance-based paper device for facile detection of microRNA via viscosity amplification and surface hydrophobicity modulation

Lang Zhang, Jun Chen, Huihui Yang, Zhenning Yu, Yuzhi Xu, Si-Yang Liu, Zong Dai and Xiaoyong Zou

Sensors and Actuators B: Chemical, 2022, 359, 131570
DOI: 10.1016/j.snb.2022.131570

Simple Chip Electrophoresis Titration of Neutralization Boundary with EDTA Photocatalysis for Distance-Based Sensing of Melamine in Dairy Products

Wen-Lin Li, Fan-Zhi Kong, Qiang Zhang, Wei-Wen Liu, Hao Kong, Xiao-Ping Liu, Muhammad-Idrees Khan, Amir Wahid, Shah Saud, Hua Xiao, Cheng-Xi Cao and Liu-Yin Fan

Anal. Chem., 2018, 90, 6710
DOI: 10.1021/acs.analchem.8b00543

True lab-in-a-syringe technology for bioassays

Lenka Hárendarčíková, Daniel Baron, Andrea Šebestová, Jan Rozsypal and Jan Petr

Talanta, 2017, 174, 285
DOI: 10.1016/j.talanta.2017.06.017

Equipment‐Free Quantitative Readout in Paper‐Based Point‐of‐Care Testing

Zedong Li, Minli You, Yuemeng Bai, Yan Gong and Feng Xu

Small Methods, 2020, 4
DOI: 10.1002/smtd.201900459

Innovative technologies for point‐of‐care testing of viral hepatitis in low‐resource and decentralized settings

L. Duchesne and K. Lacombe

Journal of Viral Hepatitis, 2018, 25, 108
DOI: 10.1111/jvh.12827

A fluorescent and colorimetric dual-channel sensor based on acid phosphatase–triggered blocking of internal filtration effect

Fanpeng Ran, Chen Ma, Yueci Xiang, Yixuan Xu, Xiaoyan Liu and Haixia Zhang

Microchim Acta, 2021, 188
DOI: 10.1007/s00604-021-04951-6

Geometrical Alignment of Multiple Fabrication Steps for Rapid Prototyping of Microfluidic Paper-Based Analytical Devices

Mohammad Rahbar, Pavel N. Nesterenko, Brett Paull and Mirek Macka

Anal. Chem., 2017, 89, 11918
DOI: 10.1021/acs.analchem.7b03796

Paper-based optical nanosensors – A review

Forough Ghasemi, Nafiseh Fahimi-Kashani, Arafeh Bigdeli, Azad H. Alshatteri, Samira Abbasi-Moayed, Sabah H. Al-Jaf, Mariam Y. Merry, Khalid M. Omer and M. Reza Hormozi-Nezhad

Analytica Chimica Acta, 2023, 1238, 340640
DOI: 10.1016/j.aca.2022.340640

What Is New in Point-of-Care Testing?

Michalis Kantartjis and Stacy E.F. Melanson

Point of Care, 2018, 17, 1
DOI: 10.1097/POC.0000000000000157

Double-Enzymes-Mediated Bioluminescent Sensor for Quantitative and Ultrasensitive Point-of-Care Testing

Yiping Chen, Yunlei Xianyu, Jing Wu, Mingling Dong, Wenshu Zheng, Jiashu Sun and Xingyu Jiang

Anal. Chem., 2017, 89, 5422
DOI: 10.1021/acs.analchem.7b00239

Integrated Distance-Based Origami Paper Analytical Device for One-Step Visualized Analysis

Tian Tian, Yuan An, Yiping Wu, Yanling Song, Zhi Zhu and Chaoyong Yang

ACS Appl. Mater. Interfaces, 2017, 9, 30480
DOI: 10.1021/acsami.7b09717

Toward Quantitative Chemical Analysis Using a Ruler on Paper: An Approach to Transduce Color to Length Based on Coffee-Ring Effect

Dagan Zhang, Biao Ma, Litianyi Tang and Hong Liu

Anal. Chem., 2018, 90, 1482
DOI: 10.1021/acs.analchem.7b03790

Use of an ether-derived 3-hydroxy-4-pyridinone chelator as a new chromogenic reagent in the development of a microfluidic paper-based analytical device for Fe(III) determination in natural waters

Tânia Moniz, Chelsea R. Bassett, M. Inês G.S. Almeida, Spas D. Kolev, Maria Rangel and Raquel B.R. Mesquita

Talanta, 2020, 214, 120887
DOI: 10.1016/j.talanta.2020.120887

A Variety of Bio-nanogold in the Fabrication of Lateral Flow Biosensors for the Detection of Pathogenic Bacteria

Nan Cheng, Zhansen Yang, Weiran Wang, Xinxian Wang, Wentao Xu and Yunbo Luo

CTMC, 2019, 19, 2476
DOI: 10.2174/1568026619666191023125020

A Snapshot of Microfluidics in Point‐of‐Care Diagnostics: Multifaceted Integrity with Materials and Sensors

Garbis Atam Akceoglu, Yeşeren Saylan and Fatih Inci

Adv Materials Technologies, 2021, 6
DOI: 10.1002/admt.202100049

Flexible Substrate-Based Devices for Point-of-Care Diagnostics

ShuQi Wang, Thiruppathiraja Chinnasamy, Mark A. Lifson, Fatih Inci and Utkan Demirci

Trends in Biotechnology, 2016, 34, 909
DOI: 10.1016/j.tibtech.2016.05.009

Silicon based solvent immersion imprint lithography for rapid polystyrene microfluidic chip prototyping

Jingdong Chen, Wenjie Wang, Weibang Ji, Shaoding Liu, Qiushu Chen, Bimin Wu, Rhima Coleman and Xudong Fan

Sensors and Actuators B: Chemical, 2017, 248, 311
DOI: 10.1016/j.snb.2017.03.146

Intelligent Platform for Simultaneous Detection of Multiple Aminoglycosides Based on a Ratiometric Paper-Based Device with Digital Fluorescence Detector Readout

Lumin Wang, Fawei Zhu, Yuqiu Zhu, Siqi Xie, Miao Chen, Yu Xiong, Qi Liu, Hua Yang and Xiaoqing Chen

ACS Sens., 2019, 4, 3283
DOI: 10.1021/acssensors.9b01845

On-Chip Stochastic Detection of Silver Nanoparticles without a Reference Electrode

Pedro G. Figueiredo, Leroy Grob, Philipp Rinklin, Kay J. Krause and Bernhard Wolfrum

ACS Sens., 2018, 3, 93
DOI: 10.1021/acssensors.7b00559

Microfluidic paper-based analytical devices with instrument-free detection and miniaturized portable detectors

Takashi Kaneta, Waleed Alahmad and Pakorn Varanusupakul

Applied Spectroscopy Reviews, 2019, 54, 117
DOI: 10.1080/05704928.2018.1457045

Recent Progress in Microfluidics-Based Biosensing

Yanling Song, Bingqian Lin, Tian Tian, Xing Xu, Wei Wang, Qingyu Ruan, Jingjing Guo, Zhi Zhu and Chaoyong Yang

Anal. Chem., 2019, 91, 388
DOI: 10.1021/acs.analchem.8b05007

Fundamentals of Image-Based Assay (IBA) System for Affordable Point of Care Diagnostics

Shahila Parween, Amit Asthana and Pradip Nahar

Microchemical Journal, 2023, 186, 108345
DOI: 10.1016/j.microc.2022.108345

Unveiling the state of the art: a systematic review and meta-analysis of paper-based microfluidic devices

Rodrigo García-Azuma, Karen Werner, Cristina Revilla-Monsalve, Oscar Trinidad, Nelly F. Altamirano-Bustamante and Myriam M. Altamirano-Bustamante

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1421831

Distance-based quantification of miRNA-21 by the coffee-ring effect using paper devices

Dagan Zhang, Chao Wu, Chengxin Luan, Peng Gao, Huan Wang, Junjie Chi and Tiantian Kong

Microchim Acta, 2020, 187
DOI: 10.1007/s00604-020-04500-7

Manipulating the hydrophobicity of DNA as a universal strategy for visual biosensing

Zhong Feng Gao, Rui Liu, Jinhua Wang, Jun Dai, Wei-Hua Huang, Mingjie Liu, Shutao Wang, Fan Xia, Shusheng Zhang and Lei Jiang

Nat Protoc, 2020, 15, 316
DOI: 10.1038/s41596-019-0235-6

A comprehensive overview on alkaline phosphatase targeting and reporting assays

Samy M. Shaban, Sae Byeok Jo, Eslam Hafez, Jeong Ho Cho and Dong-Hwan Kim

Coordination Chemistry Reviews, 2022, 465, 214567
DOI: 10.1016/j.ccr.2022.214567

Sandwich-type Surface Stress Biosensor Based on Self-Assembled Gold Nanoparticles in PDMS Film for BSA Detection

Dong Zhao, Qiang Zhang, Yixia Zhang, Yan Liu, Zhen Pei, Zhongyun Yuan and Shengbo Sang

ACS Biomater. Sci. Eng., 2019, 5, 6274
DOI: 10.1021/acsbiomaterials.9b01073

Translating in vitro diagnostics from centralized laboratories to point-of-care locations using commercially-available handheld meters

JingJing Zhang, Tian Lan and Yi Lu

TrAC Trends in Analytical Chemistry, 2020, 124, 115782
DOI: 10.1016/j.trac.2019.115782

Advances in gas pressure-based portable biosensing

Lu Shi, Chaoyong Yang and Yan Jin

TrAC Trends in Analytical Chemistry, 2024, 180, 117897
DOI: 10.1016/j.trac.2024.117897

Polarization holographic microscope slide for birefringence imaging of anisotropic samples in microfluidics

Yang Yang, Hong-Yi Huang and Cheng-Shan Guo

Opt. Express, 2020, 28, 14762
DOI: 10.1364/OE.389973

A self-powered rotating paper-based analytical device for sensing of thrombin

Qingling Li, Yuehan Xu, Ji Qi, Xiaoli Zheng, Shudi Liu, Dong Lin, Liangwei Zhang, Ping Liu, Bowei Li and Lingxin Chen

Sensors and Actuators B: Chemical, 2022, 351, 130917
DOI: 10.1016/j.snb.2021.130917

Microfluidic devices with simplified signal readout

Yingzhou Tao, Haicong Shen, Kunyue Deng, Huimin Zhang and Chaoyong Yang

Sensors and Actuators B: Chemical, 2021, 339, 129730
DOI: 10.1016/j.snb.2021.129730

Distance-based carcinoembryonic antigen assay on microfluidic paper immunodevice

Ying Chen, Weiru Chu, Wei Liu and Xiaoyan Guo

Sensors and Actuators B: Chemical, 2018, 260, 452
DOI: 10.1016/j.snb.2017.12.197

Distance-based microfluidic assays for instrument-free visual point-of-care testing

Mashooq Khan, Binglu Zhao, Wenli Wu, Mei Zhao, Yanhui Bi and Qiongzheng Hu

TrAC Trends in Analytical Chemistry, 2023, 162, 117029
DOI: 10.1016/j.trac.2023.117029

Development of an immunoassay lollipop using syringe-autoinjected visual distance readout for point-of-care testing

Cuili Li, Maojie Xiang, Jie Liu, Shuting Zhang, Haojie Li and Guanglei Fu

Anal Bioanal Chem, 2025
DOI: 10.1007/s00216-025-06039-z

Analysis of free chlorine in aqueous solution at very low concentration with lateral flow tests

K. Uta Schwenke, Dieter Spiehl, Marcel Krauße, Laura Riedler, Anna Ruppenthal, Klaus Villforth, Tobias Meckel, Markus Biesalski, Daniel Rupprecht and Gerhard Schwall

Sci Rep, 2019, 9
DOI: 10.1038/s41598-019-53687-0

Point-of-care-testing of nucleic acids by microfluidics

Lu Zhang, Baozhi Ding, Qinghua Chen, Qiang Feng, Ling Lin and Jiashu Sun

TrAC Trends in Analytical Chemistry, 2017, 94, 106
DOI: 10.1016/j.trac.2017.07.013

Fabrication of cost-effective and efficient paper-based device for viscosity measurement

Anirudh Rayaprolu, Saurabh Kumar Srivastava, Ketan Anand, Lavleen Bhati, Amit Asthana and Ch Mohan Rao

Analytica Chimica Acta, 2018, 1044, 86
DOI: 10.1016/j.aca.2018.05.036

An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology

Yongyuan Liang, Mingsheng Ma, Faqiang Zhang, Feng Liu, Zhifu Liu, Dong Wang and Yongxiang Li

Sensors, 2019, 19, 1189
DOI: 10.3390/s19051189

Development of a C-reactive protein quantification method based on flow rate measurement of an ink solution pushed out by oxygen gas generated by catalase reaction

Kuizhi Qu, Kazuhiro Morioka, Konoka Nakamura, Shoji Yamamoto, Akihide Hemmi, Atsushi Shoji and Hizuru Nakajima

Microchim Acta, 2024, 191
DOI: 10.1007/s00604-023-06108-z

Recent Advances in Electrochemical Immunosensors

Wei Wen, Xu Yan, Chengzhou Zhu, Dan Du and Yuehe Lin

Anal. Chem., 2017, 89, 138
DOI: 10.1021/acs.analchem.6b04281

Naked-Eye Readout Distance Quantitative Lateral Flow Assay Based on the Permeability Changes of Enzyme-Catalyzed Hydrogelation

Jia Liu, Mengran Li, Qiuhong Man, Li-hao Huang, Jiaxi Wang, Mingxia Gao and Xiangmin Zhang

Anal. Chem., 2023, 95, 8011
DOI: 10.1021/acs.analchem.3c00892

Facile and Low-Cost Fabrication of a Thread/Paper-Based Wearable System for Simultaneous Detection of Lactate and pH in Human Sweat

Gang Xiao, Jing He, Yan Qiao, Feng Wang, Qingyou Xia, Xin Wang, Ling Yu, Zhisong Lu and Chang-Ming Li

Adv. Fiber Mater., 2020, 2, 265
DOI: 10.1007/s42765-020-00046-8

Towards microfluidic-based exosome isolation and detection for tumor therapy

Jie Wang, Peng Ma, Daniel H. Kim, Bi-Feng Liu and Utkan Demirci

Nano Today, 2021, 37, 101066
DOI: 10.1016/j.nantod.2020.101066

Distance-based detection of calcium ions with hydrogels entrapping exhaustive ion-selective nanoparticles

Xinfeng Du, Jingying Zhai, Dingxuan Zeng, Fangyi Chen and Xiaojiang Xie

Sensors and Actuators B: Chemical, 2020, 319, 128300
DOI: 10.1016/j.snb.2020.128300

Development of an Inkless, Visual Volumetric Chip Operated with a Micropipette

Hyogu Han and Suk-Jung Choi

BioChip J, 2021, 15, 179
DOI: 10.1007/s13206-021-00021-4

Ion-Exchange Based Immobilization of Chromogenic Reagents on Microfluidic Paper Analytical Devices

Mohammad Rahbar, Aaron R. Wheeler, Brett Paull and Mirek Macka

Anal. Chem., 2019, 91, 8756
DOI: 10.1021/acs.analchem.9b01288

A Distance-Based Microfluidic Paper-Based Biosensor for Glucose Measurements in Tear Range

Samira Allameh and Mohsen Rabbani

Appl Biochem Biotechnol, 2022, 194, 2077
DOI: 10.1007/s12010-022-03817-8

A portable pencil-like immunosensor for point-of-care testing of inflammatory biomarkers

Rongbin Nie, Jingwen Huang, Xuexue Xu and Li Yang

Anal Bioanal Chem, 2020, 412, 3231
DOI: 10.1007/s00216-020-02582-z

Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip

Ji Qi, Bowei Li, Dong Lin, Zhiqiang Du, Longwen Fu, Xiaoyan Wang, Zhiyang Zhang, Liqiang Luo and Lingxin Chen

Anal. Chem., 2023, 95, 10486
DOI: 10.1021/acs.analchem.3c00947

Mass transfer and kinetic characteristics for CO2 absorption in microstructured reactors using an aqueous mixed amine

Mohsin Pasha, Guangxiao Li, Minjing Shang, Saier Liu and Yuanhai Su

Separation and Purification Technology, 2021, 274, 118987
DOI: 10.1016/j.seppur.2021.118987

Distance and Color Change Based Hydrogel Sensor for Visual Quantitative Determination of Buffer Concentrations

Renjie Wang, Xinfeng Du, Jingying Zhai and Xiaojiang Xie

ACS Sens., 2019, 4, 1017
DOI: 10.1021/acssensors.9b00186

Ultrasensitive Detection of miRNA via CRISPR/Cas12a Coupled with Strand Displacement Amplification Reaction

Shaoqiong Feng, Hanjun Chen, Ziao Hu, Tingting Wu and Zhihong Liu

ACS Appl. Mater. Interfaces, 2023, 15, 28933
DOI: 10.1021/acsami.3c03399

Experimental study of carbon dioxide desorption from ethanolamine/non-aqueous CO2-rich absorbent solvent using microchannel

Dan Gao, Youwei Qi, Jiaxi Yang and Heng Zhang

Separation and Purification Technology, 2024, 331, 125651
DOI: 10.1016/j.seppur.2023.125651

High-throughput deposition of chemical reagents via pen-plotting technique for microfluidic paper-based analytical devices

Mohammad Rahbar, Pavel N. Nesterenko, Brett Paull and Mirek Macka

Analytica Chimica Acta, 2019, 1047, 115
DOI: 10.1016/j.aca.2018.09.006

A microfluidic immunosensor for visual detection of foodborne bacteria using immunomagnetic separation, enzymatic catalysis and distance indication

Gaozhe Cai, Lingyan Zheng, Ming Liao, Yanbin Li, Maohua Wang, Ning Liu and Jianhan Lin

Microchim Acta, 2019, 186
DOI: 10.1007/s00604-019-3883-x

Novel Wax Valves To Improve Distance-Based Analyte Detection in Paper Microfluidics

Chang Chen, Litao Zhao, Han Zhang, Xiaoshuang Shen, Yonggang Zhu and Huaying Chen

Anal. Chem., 2019, 91, 5169
DOI: 10.1021/acs.analchem.8b05764

A quantitative foam immunoassay for detection of Escherichia coli O157:H7 based on bimetallic nanocatalyst‑gold platinum

Lu Liu, Jing Liu, Hui Huang, Yongxin Li, Guangying Zhao and Wenchao Dou

Microchemical Journal, 2019, 148, 702
DOI: 10.1016/j.microc.2019.05.016

Application of some nanoparticles in the field of veterinary medicine

Fady Sayed Youssef, Hossny Awad El-Banna, Hesham Youssef Elzorba and Ahmed Mohamed Galal

International Journal of Veterinary Science and Medicine, 2019, 7, 78
DOI: 10.1080/23144599.2019.1691379

An Open Pit Nanofluidic Tool: Localized Chemistry Assisted by Mesoporous Thin Film Infiltration

Magalí Mercuri, Karina A. Pierpauli, Claudio L. A. Berli and Martín G. Bellino

ACS Appl. Mater. Interfaces, 2017, 9, 16679
DOI: 10.1021/acsami.7b03080

Nanomaterials-driven paper-based biosensors for food contaminants detection: Classification, mechanism and applications

Yang Song, Xiaoyun Xu and Hengyi Xu

Coordination Chemistry Reviews, 2025, 532, 216512
DOI: 10.1016/j.ccr.2025.216512

Visual detection of the prostate specific antigen via a sandwich immunoassay and by using a superwettable chip coated with pH-responsive silica nanoparticles

Jian Bang Gao, Ei Ei Sann, Xin Yu Wang, Cui Ye, Rui Liu and Zhong Feng Gao

Microchim Acta, 2019, 186
DOI: 10.1007/s00604-019-3662-8

Paper-Based Device for Naked Eye Urinary Albumin/Creatinine Ratio Evaluation

Ryuya Hiraoka, Kento Kuwahara, Yun-Chiao Wen, Tzung-Hai Yen, Yuki Hiruta, Chao-Min Cheng and Daniel Citterio

ACS Sens., 2020, 5, 1110
DOI: 10.1021/acssensors.0c00050

Application of Microfluidics for Bacterial Identification

Fraser Daniel, Delaney Kesterson, Kevin Lei, Catherine Hord, Aarti Patel, Anastasia Kaffenes, Harrshavasan Congivaram and Shaurya Prakash

Pharmaceuticals, 2022, 15, 1531
DOI: 10.3390/ph15121531

The development of a paper-based distance sensor for the detection of Pb2+ assisted with the target-responsive DNA hydrogel

Jinpeng Liu, Yanhui Bi, Wenjun Tai, Yong Wei, Qiang Zhang, Anna Liu, Qiongzheng Hu and Li Yu

Talanta, 2023, 257, 124344
DOI: 10.1016/j.talanta.2023.124344

A low-fouling electrochemical immunosensor based on reduced graphene oxide and terbium@amine-functionalized fibrous silica-modified screen-printed carbon electrodes for ratiometric detection of carcinoembryonic antigen (CEA) in serum samples

Ali A. Majeed, Ibrahim Saeed Gataa, Zaman Abdalhussein Ibadi Alaridhee, Mohammed B. Alqaraguly, Soud Khalil Ibrahim, Shoira Formanova, Hayder Hamid Abbas Al-Anbari, Majid S. Jabir, Hasan Majdi, Yahya Yahya Zaki Fareed, Muthena Kariem and Mosleh Mohammad Abomughaid

Microchemical Journal, 2025, 210, 112928
DOI: 10.1016/j.microc.2025.112928

Paper chip-based colorimetric biosensor for glucose by using CuFe2O4@GO as nanozyme

Yueran Ren, Xiaomin Zuo, Ziqiang Liu, Minghui Yu, Bingqian Zhou, Yangyang Xue, Lili Zhu and Rui Yang

Microchemical Journal, 2024, 206, 111504
DOI: 10.1016/j.microc.2024.111504

Read-by-eye quantification of aluminum (III) in distance-based microfluidic paper-based analytical devices

Michael P. Nguyen, Sydney P. Kelly, John B. Wydallis and Charles S. Henry

Analytica Chimica Acta, 2020, 1100, 156
DOI: 10.1016/j.aca.2019.11.052